ACS Omega
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2026
·
IF 5.2
Yuzhen Dong,Jingwu Zhao,Yang Lv,Chunhao Wang,Mingshuo Mao,Zhongxin Ping,Yinghui Yang,Wanting Xu,Lankun Zhang,Fangxiao Kan,Fang Xie
Liquid-metal-based magnetic droplet robot attract considerable attentions due to their noncontact operation, rapid response, strong maneuverability, and deformability. However, prolonged use leads to gradual alloying between the liquid-metal and magnetic particles, which causes a progressive decline in magnetic performance until complete loss. In this work, we report a strategy to address both the alloying and interfacial nonwettability between the liquid-metal and magnetic particles via a poly(methyl methacrylate) (PMMA) layer onto the magnetic particles via atom transfer radical polymerization (ATRP). Subsequently, liquid-metal-based magnetic droplet robot was constructed to perform rapid locomotion and targeted cargo transport in complex environments under actuation of external magnetic field. Finally, liquid-metal-based magnetic droplet robot can achieve reversible circuit switching or long-term repair of damaged circuits. This work presents a new methodology for fabricating liquid-metal-magnetic particle composites. The resultant droplet robot exhibit outstanding performance, thereby holding significant promise for future use in biomedical, electronic, and related fields.
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PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
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2016
·
IF 3.014
Qian Feng,Dongyan Tang,Haitao Lv,Weile Zhang,Wenbo Li
We reported on the fabrication of thermo-responsive polymers of poly( N -isopropylacrylamide) (PNIPAM) graft ZnO by surface-initiated atom transfer radical polymerization (SI-ATRP) to contribute the characteristics of the grafted PNIPAM, meanwhile, without sacrificing the properties of ZnO. The structures of nanoparticles and the grafted polymer were confirmed by XRD and FT-IR and the interactions between the two components were studied by XPS . The morphology of ZnO NPs-PNIPAM nanocomposites was observed by SEM images and a thin layer of polymers (2 nm) formed around NPs was measured by TEM. EDS mapping images revealed the even distribution polymers on the surface of ZnO NPs. Based on the TG results, the grafting density of ATRP initiators at the surface of ZnO NPs was estimated to be 0.7 nm 2 /initiator. Furthermore, photodegradation of Rhodamine B (Rh-B) in the presence of nanocomposites revealed that ZnO NPs-PNIPAM exhibited photocatalysis , temperature-controlled switching and good recycling performance, indicating the significant potential applications in the practical applications.
研究领域:
材料科学
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化学工程
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环境科学
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DOI
高影响因子
International Journal of Nanomedicine
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2018
·
IF 4.37
Jiao Liu,Jie Cao,Jianhua Cao,Shangcong Han,Yan Liang,Mingfeng Bai,Yong Sun
Introduction Nanoparticles are increasingly used as drug carriers for oral administration. The delivery of drug molecules is largely dependent on the interaction of nanocarriers and gastrointestinal (GI) mucus, a critical barrier that regulates drug absorption. It is therefore important to understand the effects of physical and chemical properties of nanocarriers on the interaction with GI mucus. Unfortunately, most of the nanoparticles are unable to be prepared with satisfactory structural monodispersity to comprehensively investigate the interaction. With controlled size, shape, and surface chemistry, copolymers are ideal candidates for such purpose. Materials and methods We synthesized a series of diblock copolymers via the atom transfer radical polymerization method and investigated the GI mucus permeability in vitro and in vivo. Results Our results indicated that uncharged and hydrophobic copolymers exhibited enhanced GI absorption. Conclusion These results provide insights into developing optimal nanocarriers for oral administration.
研究领域:
药学
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材料科学
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生物医学工程
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PubMed
高影响因子
CELLULOSE
·
2019
·Vol. 26
·期 9
·5305-5319
·
IF 3.917
Bai Liangjiu,Jiang Xinyan,Sun Zhixiang,Pei Zhaoxia,Ma Anyao,Wang Wenxiang,Chen Hou,Yang Huawei,Yang Lixia,Wei Donglei
Abstract Self-healing hydrogels with excellent toughness and mechanical strength are particularly desirable for practical application. In this paper, green and environmentally friendly cellulose nanocrystals (CNCs) were successfully modified on the surface via metal-free photoinduced electron transfer atom transfer radical polymerization (PET-ATRP). Surface-initiated PET-ATRP was achieved by using 4-vinylpyridine (4VP) as functional monomer, 10-phenylphenothiazine (Ph-PTZ) as photocatalyst and ultraviolet light (365 nm) as light source, respectively. The prepared P4VP-CNCs hybrid materials (CNCs@P4VP) were used as green reinforcement to obtain self-healing nanocomposite hydrogels by electrostatic interactions. As a result, the nanocomposite hydrogels displayed outstanding mechanical (6.6 MPa at a strain of 921.6%) and self-healing (85.9% after repairing 6 h) properties. This work provides a promising green method for designing novel self-healing nanocomposite hydrogels with high strength. Graphical abstract
研究领域:
材料科学
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化学工程
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纳米技术
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Zian Wang,Shuqiang Peng,Lixin Wu,Zixiang Weng
Benefiting from its low surface energy, low surface tension and high efficiency of droplet mobility, Slippery liquid infused porous surfaces (SLIPS) are being applied in the fields like self-cleaning, anti-icing, thermal transfer etc . Nevertheless, the short service life and the complex preparation procedures are still hindering its further practical applications. In this work, with the combination of UV-curing technique and atom transfer radical polymerization (ATRP) treatment, superhydrophobic surface (SHS) with a chemical stability in a corrosive environment and an excellent mechanical resistance is prepared in a facile way. Profiting from the ultra-high affinity between SHS and lubricant oil, as-prepared SLIPS based on SHS exhibited an ultra-long service life. Compared with other commonly used SLIPS, the service life of resultant SLIPS in this work extends 50 times, which can bear a 3000 mL of continuous water droplet washing. As-prepared SLIPS is a promising candidate for the application in self-cleaning.
研究领域:
材料科学
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化学工程
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DOI
高影响因子
CERAMICS INTERNATIONAL
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2015
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IF 2.605
Na Sun,Xiangjun Meng,Zhenggang Xiao
In order to improve the dispersibility of nanoparticles in polymer matrix , a feasible processing way for grafting high density hydrophobic polymer on the surface of silicon nitride (Si 3 N 4 ) nanoparticles was carried out by an atom transfer radical polymerization (ATRP) method. The ATRP initiators were first immobilized on the surface of Si 3 N 4 nanoparticles by using 3-aminopropyltriethoxysilane coupling agent and 2-bromoisobutyryl bromide, and then the polymerization of methyl methacrylate was initiated and propagated on the surface of Si 3 N 4 nanoparticles by ATRP reaction. The chemical groups, size, morphology, grafting content, and colloidal thermal stability of PMMA–Si 3 N 4 particles were studied by Fourier transform infrared (FTIR), transmission electron microscopy (TEM) and thermogravimetric analysis (TGA). Results indicate that the grafting of polymer on the surface of Si 3 N 4 nanoparticles is successful and the grafting content of PMMA reaches 60.4%. Moreover, the grafted polymer chains have changed the surface properties of Si 3 N 4 nanoparticles and enhanced their dispersibility in organic media.
研究领域:
材料科学
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高分子化学
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DOI
高影响因子
ACS Applied Materials & Interfaces
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2017
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IF 7.504
Wei Jiang,Xinghuo Wang,Jiawen Chen,Ying Liu,Haobo Han,Yi Ding,Quanshun Li,Jun Tang
An enzyme mimic harboring iron porphyrin (DhHP-6) embedded in zeolite imidazolate framework-8 (ZIF-8) was constructed through a biomimetic mineralization approach to obtain composite DhHP-6@ZIF-8. The composite was then used as a catalyst in the atom transfer radical polymerization (ATRP) of poly(ethylene glycol) methyl ether methacrylate (PEGMA500) in which poly(PEGMA500) could be synthesized with monomer conversion of 76.1% and Mn of 45 900 g/mol, stronger than that obtained when using free DhHP-6 as a catalyst. More importantly, it could efficiently overcome the drawbacks of free DhHP-6 and achieve the easy separation of DhHP-6 from the catalytic system and the elimination of iron residues in the synthesized polymer. In addition, it exhibited an enhanced recyclability with monomer conversion of 75.7% after five cycles and favorable stability during the ATRP reaction with <3.0% of DhHP-6 release within 100 h. Thus, the enzyme mimic–ZIF-8 composite developed through biomimetic mineralization can be potentially used as an effective catalyst for preparing well-defined polymers with biomedical applications.
研究领域:
材料科学
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生物医学工程
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DOI
PubMed
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
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2016
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IF 3.902
Xingxing Jin,Jiang Yuan,Jian Shen
A low-fouling zwitterionic surface strategy has been proven to be promising and effective for repelling nonspecific adsorption of proteins, cells and bacteria, which may eventually induce adverse pathogenic problems such as thrombosis and infection. Herein, a multi-step process was developed by a combination of mussel-inspired chemistry and surface-initiated atom transfer radical polymerization (SI-ATRP) technique for improving hemocompatible and anti-biofouling properties. Polyethylene terephthalate (PET) sheets were first treated with dopamine, and then the bromoalkyl initiators were immobilized on the poly(dopamine) functionalized surfaces, followed by surface-initiated activators regenerated by electron transfer atom transfer radical polymerization (ARGET ATRP) of 2-(dimethylamino) ethyl methacrylate (DMAEMA) monomer. Subsequently, the resulting PET sheets were ring-opening reacted with 1,3-propiolactone (PL) and 1,3-propanesultone (PS) to afford polycarboxybetaine and polysulfobetaine brushes, respectively. Characterizations of the PET sheets were undertaken by attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR), atomic force microscope (AFM), water contact angle (WCA) measurements, and X-ray photoelectron spectroscopy (XPS) analysis, respectively. The conversion rates of PDMAEMA to polyzwitterions were evaluated by XPS analysis. The remained PDMAEMA(weak cationic) and formed zwitterions(neutral) would form a synergetic antifouling and antibacterial surface. Hemocompatible and anti-biofouling properties were evaluated by total adsorption of protein as well as the adhesion of platelet, cell and bacterium. Zwitterionic polymer brushes grafted PET sheets showed outstanding hemocompatibility featured on reduced platelet adhesion and repelled protein adsorption. Meanwhile, the grafted PET sheets exerted excellent anti-biofouling property characterized by the resisted adhesion of Escherichia coli and 3T3 cells. In summary, zwitterionic polymer brushed modified PET sheets have a great potential for biomedical applications.
研究领域:
材料科学
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生物医学工程
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高分子化学
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DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
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2013
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IF 4.093
Wen-Wen Yue,Hui-Juan Li,Tao Xiang,Hui Qin,Shu-Dong Sun,Chang-Sheng Zhao
Zwitterionic polymer of poly(sulfobetaine methacrylate) (PSBMA) was grafted from polysulfone (PSf) membrane via surface-initiated atom transfer radical polymerization (SI-ATRP). The polysulfone- graft -poly(sulfobetaine methacrylate) (PSf- g -PSBMA) membrane was characterized by scanning electron microscopy (SEM), atomic force microscopy (AFM), attenuated total reflectance-Fourier transform infrared spectra (ATR-FTIR), X-ray photoelectron spectroscopy (XPS), and static water contact angle (WCA) measurement. The membrane showed excellent protein antifouling property though the water flux decreased to some content; nevertheless, the protein rejection ratio of the modified membrane was not change. The biocompatibility of the membrane was characterized by protein adsorption, hemolysis assay, platelet adhesion, plasma recalcification time, activated partial thromboplastin time (APTT), thrombin time (TT) and cytotoxicity experiments, and the results indicated that the modified PSf membrane had good blood compatibility and cytocompatibility.
研究领域:
材料科学
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生物医学工程
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高分子化学
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膜技术
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高影响因子
MICROCHIMICA ACTA
·
2021
·Vol. 188
·期 11
·1-9
·
IF 5.833
Wang Fei,Xu Yang,Han Hongliang,Ma Zhanfang
A novel biosensing interface for tumor markers was designed based on the atom transfer radical polymerization (ATRP) of poly(isopropenylphenol) (PPPL) in situ initiated by the fixing of p-chloromethyl benzoic acid on the surface of amino-modified electrodes. It was found that the electrochemical activity of PPPL itself can provide sufficient signals for these biosensors, which can avoid signal leakage and streamline the interface modification process. Cu(II) ions absorbed on the carbon spheres and then were released via acid stimulation to act as a catalyst to participate in the interface polymerization with ATRP. As the concentration of targets increased, more Cu(II) ions were released, and the electrochemical signal of polymers was enhanced. Therefore, the sensitive detection of carbohydrate antigen 19–9 (CA19-9) as a model target was achieved, with an ultralow limit of detection of 39 µU mL −1 and wide detection range from 100 µU mL −1 to 100 U mL −1 under optimal conditions. Furthermore, this method achieved satisfying performance in human blood serum with good inter-assay precision ( RSD < 6%) and satisfactory recovery of ~ 99–105%. According to the results, this work is of great significance for constructing biosensor interfaces via in situ polymerization. Graphical abstract A novel biosensing interface for tumor marker was designed based on atom transfer radical polymerization (ATRP), which poly(isopropenylphenol) with electrochemical signal was fabricated in situ on electrode.
研究领域:
分析化学
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生物传感器
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材料科学
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癌症研究
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DOI
PubMed
高影响因子
Materials Today Communications
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2023
·
IF 3.8
Jialin Li,Shanshan Zhou,Hao Pang,Yuewen Huang,Bin Wang
Star-shaped superplasticizers exhibited excellent dispersion performance on cement paste , but the molecular structure remained poorly controlled. This study develops three star-shaped block superplasticizers via atom transfer radical polymerization to investigate their effects on fluidity and early hydration in the Portland cement system. The three star-shaped block superplasticizers with acid to ether monomer ratio of 28, 36 and 100, are marked as SPCE-1, SPCE-2 and SPCE-3 respectively. Fluidity test shows that SPCE-1 and SPCE-3 with higher hydrodynamic radius exhibit better initial fluidizing effect than SPCE-2. Besides, there is competitive adsorption of SPCEs between the clinker phase and nano-ettringite in pore solution. SPCE-1 behaves best in fluidity retention due to the increase of adsorption amount over hydration time. A dispersion mechanism based on the extended-DLVO theory was proposed that SPCEs reduce hydrophobic interaction between cement grains and prevent agglomeration between cement grains and air bubbles.
研究领域:
材料科学
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化学工程
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高影响因子
Polymer Chemistry
·
2023
·Vol. 14
·期 24
·2930-2939
·
IF 4.6
Yue Zhang,Rong Zhao,Yan Qin,Jianguo Yi,Jimin Zhang,Xiaoai Chen
Light-induced metal-free atom transfer radical polymerization (ATRP) was applied in combination with the self-condensing vinyl polymerization (SCVP) to prepare hyperbranched multiarm copolymers for further peptide conjugation. Di(ethylene glycol) methyl ether methacrylate (DEGMA) was copolymerized with the inimer 2-(2-bromo-2-methylpropanoyloxy)ethyl methacrylate (BMA) through the metal-free ATRP, affording the hyperbranched polymer hPDEGMA. Further polymerization of pyridyl disulfide ethyl methacrylate (DSMA) with hPDEGMA as the macroinitiator led to the formation of the hyperbranched multiarm copolymer hPDEGMA-star-PDSMA. Glutathione as a model peptide was conjugated to hPDEGMA-star-PDSMA through the thiol-disulfide exchange reaction and the copolymer peptide conjugate hPDEGMA-star-PGS was obtained. Three hyperbranched multiarm copolymer peptide conjugates were prepared with close molecular weights but different degrees of branching (DB) and their self-assembly behaviors were studied. All three conjugates self-assembled into vesicles with narrow distributions. The conjugates with lower DB self-assembled into bilayer vesicles while the one with higher DB self-assembled into monolayer vesicles. The cysteine-modified targeting peptide HAIYPRH (T7) was also conjugated to hPDEGMA-star-PDSMA affording hPDEGMA-star-PT7. The self-assemblies of hPDEGMA-star-PT7 exhibited low toxicity towards the MCF-7 cells and could be internalized by the MCF-7 cells.
研究领域:
高分子化学
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材料科学
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纳米技术
·
生物医学工程
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DOI
高影响因子
危险品化学品经营许可证（带存储）