Analytical Methods
·
2015
·Vol. 8
·期 18
·3768-3773
·
IF 1.821
Shuguang Yan,Rongcai Song,Yurong Tang
Ag2Te nanocrystals (NCs) were prepared from inexpensive and environmentally friendly raw materials by a facile route using liquid precursors at low temperatures under atmospheric pressure. The as-prepared Ag2Te NCs have been characterized by UV-vis spectroscopy, TEM and XPS. We have demonstrated that the enhancement of resonance Rayleigh scattering (RRS) was observed when sulfide ions were injected into the prepared Ag2Te NCs through the interaction between sulfide ions and Ag2Te NCs. A result which leads to a change in the conformation of the Ag2Te NCs and formed nanocomposite Ag2S/Ag2Te NCs was derived, and a novel RRS system for direct detection of sulfide was established. The possible enhancement RRS mechanism is discussed in this work. The resulting RRS sensor enables the detection of sulfide ions with a limit of detection reaching 7.8 ng mL−1 (3σ/K) in a wide linear range from 0.026 μg mL−1 (10σ/K) to 9.87 μg mL−1. The practicality of this probe for the detection of sulfide ions in urban river water samples has been validated and its advantages of simplicity, sensitivity, selectivity, and low cost have been demonstrated. The recovery of spiked sulfide ions in urban river water samples ranges from 96% to 103%. The relative standard deviation (RSD) for eleven replicate detections is 2.6%.
研究领域:
分析化学
·
环境科学
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DOI
高影响因子
ACS Omega
·
2025
·
IF 4.3
Wenwen Chen,Rong Chen,Yutong Sun,Han Wang,Zhenyu Chen,Liqun Chen,Guoming Huang,Guifang Lin,Dengke Hong
The gut bacteria not only play a crucial role in maintaining human health but also exhibit close associations with the occurrence of numerous diseases. Understanding the physiological and pathological functions of gut bacteria and enabling early diagnosis of gut diseases heavily relies on accurate knowledge about their in vivo distribution. Consequently, there is a significant demand for noninvasive imaging techniques capable of providing real-time localization information regarding gut bacteria. In this work, we developed a second near-infrared (NIR-II) fluorescent nanoprobe labeling-based visualization strategy for real-time tracking of the biodistribution of Gram-negative bacteria in the gastrointestinal tract of mice. By utilizing positively charged silver sulfide quantum dots (Ag2S QDs) as NIR-II nanoprobes and exploiting electrostatic interactions to efficiently label the Gram-negative probiotic Escherichia coli Nissle 1917 with negative surface charges, we have achieved rapid and effective labeling. Leveraging the exceptional NIR-II fluorescent performance of Ag2S QDs, our approach enables high spatiotemporal resolution visualization via NIR-II imaging in mouse gastrointestinal areas where Ag2S QD-labeled probiotics are present, facilitating real-time in vivo tracking capabilities for these labeled probiotics. This work not only establishes a powerful intestinal bacterial imaging strategy but also introduces novel concepts for constructing nanomaterial-bacteria hybrid systems.
CAS / MDL:
研究领域:
生物医学工程
·
微生物学
·
分子影像学
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DOI
PubMed
高影响因子
DALTON TRANSACTIONS
·
2013
·Vol. 43
·期 10
·3990-3998
·
IF 3.806
Junli Wang,Hui Feng,Kangmin Chen,Weiling Fan,Qing Yang
A facile catalytic growth route was developed for the low-temperature solution synthesis of Ag2S–CdS matchstick-like heteronanostructures in oleylamine, which are composed of a Ag2S spherical head and a CdS rod-like stem. Ag2S nanoseeds acted as an effective catalyst for the growth of CdS nanorods and remained at the tip of the resultant nanorods, leading to the formation of Ag2S–CdS heterostructures with a matchstick shape. The diameter of the Ag2S heads and the length of the CdS stems could be easily controlled by varying the molar ratios of the Ag/Cd precursors. The differential scanning calorimetry (DSC) and variable-temperature X-ray diffraction (XRD) studies confirmed that Ag2S catalytic seeds underwent a phase change, that is, they were in a high-temperature superionic conducting cubic structure during the CdS nanorod growth and then converted to a low-temperature monoclinic crystal structure as the reaction was cooled to room temperature. The influence of synthetic temperature on the product morphology was investigated and the morphological evolution at different growth stages was monitored using transmission electron microscopy (TEM). Furthermore, the growth kinetics of the Ag2S–CdS matchstick-like heteronanostructures, including the dissolution, nucleation and growth of CdS within the Ag2S catalyst, was reasonably discussed on the basis of the structural characteristics of the superionic cubic Ag2S catalyst and the low solubility of CdS in Ag2S derived from the Ag2S–CdS binary phase diagram.
研究领域:
材料化学
·
纳米科学与技术
·
无机化学
·
物理化学
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半导体材料
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DOI
高影响因子
ACS Applied Materials & Interfaces
·
2026
·
IF 7.8
Hong Mingdong,Yang Shengyi,Zou Guanzhen,Liu Mingzhu,Wang Yao,Bai Haoran,Fan Yaoyao,Tao Mengyao,Zou Bingsuo,Jiang Yurong
High-performance infrared photodetection is essential for emerging applications such as optical communication and night vision; however, extending the spectral response range beyond intrinsic bandgap limits remains a significant challenge for traditional crystalline materials. Herein, a facile synthesis of silver sulfide (Ag 2 S) crystalline nanodots (CNDs) and Ag 2 S amorphous nanodots (ANDs) to extend the responsive wavelength beyond the bandgap limits of conventional Ag 2 S colloidal quantum dots (CQDs) is reported. As compared to Ag 2 S-CNDs as the active layer, our dual-band infrared photodetector ITO/ZnO/PbS/Ag 2 S-ANDs/MXene/Au, in which the active layer of Ag 2 S-ANDs is in amorphous nanodots, exhibited dramatically superior performance of 100-fold higher photocurrent under 15.6 mW/cm 2 1550 nm illumination. As a result, a high specific detectivity of 2.32 × 10 13 Jones with a responsivity of 1.05 A/W is obtained from the photodetector ITO/ZnO/PbS/Ag 2 S-ANDs/MXene/Au under 0.2 μW/cm 2 980 nm illumination at 0 V, as well as a high specific detectivity of 4.47 × 10 11 Jones with a responsivity of 0.01 A/W under 8.5 μW/cm 2 1550 nm illumination, showing its higher performance among the top PbS CQD-based photodetectors. Therefore, this work demonstrates that amorphous inorganic nanomaterials offer a highly promising strategy for broadening the detection wavelength range for high-performance photodetectors.
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高影响因子
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
·
2020
·
IF 2.985
Feng Lu,Wenwen Ju,Ning Zhao,Ting Zhao,Chen Zhan,Qi Wang,Quli Fan,Wei Huang
With significantly decreased light scattering and tissue autofluorescence , fluorescence imaging in the second near infrared (NIR-II, 1000-1700 nm) region has been heavily explored in biomedical field recently. Silver sulfide quantum dots (Ag 2 S QDs) with unique optical properties were one of the most classic NIR-II imaging probes. However, the Ag 2 S QDs for in vivo purpose were mainly obtain by oil phase-based high-temperature route at present. Here, we proposed a mild aqueous route to prepare NIR-II emissive Ag 2 S QDs for in vivo tumor imaging. Original Ag 2 S QDs was obtained by mixing sodium sulfide and silver nitrate in a thiol-terminated polyethylene glycol (mPEG-SH) solution. Treating the original Ag 2 S QDs with extra mPEG-SH ligands produced highly PEGyalted Ag 2 S QDs. These re-PEGylated Ag 2 S QDs exhibited much better blood circulation and tumor accumulation in vivo comparing with the original ones, which can serve as excellent tumor imaging probes. The whole-body blood vessel imaging of living mice was achieved with high resolution, the bio-distribution of these QDs were studied by NIR-II imaging as well. This work also highlighted the importance of ligand density for tumor targeting.
研究领域:
生物医学工程
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材料科学
·
纳米技术
·
癌症研究
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成像科学
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DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2022
·
IF 6.371
Zhentao Song,Limin Wang
In this work, the heterostructure of CoS x /Ag/Ag 2 S/ZnIn 2 S 4 (CAAZ) was synthesized by photodeposition reaction, cation exchange and low temperature solvothermal reaction. The degradation kinetic constants of TC and MO by CAAZ-3 within 60 min were 2.5 and 7.1 times that of pure ZnIn 2 S 4 , respectively, and CAAZ-3 still maintained good catalytic activity after 5 cycles. ZnIn 2 S 4 nanosheet is attached to the surface of CoS x hollow structure, which increases the reactive active site and improves the efficiency of light utilization. Notably, the introduction of Ag/Ag 2 S nanoparticles accelerates the conduction rate of photogenerated charge between the interfaces, which is consistent with the results of photochemical tests. It was found that the synergistic interaction of •O 2 - and h + played an important role in the degradation process of TC molecules. This study focuses on the development of photocatalysts for the efficient degradation of organic pollutants and theoretically demonstrates the importance of optimizing conductive interfaces for improving photocatalytic activity.
研究领域:
材料科学
·
环境科学
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DOI
高影响因子
JOURNAL OF NANOPARTICLE RESEARCH
·
2014
·Vol. 16
·期 12
·1-10
·
IF 2.278
Zhao Qian,Chen Shenna,Zhang Lingyang,Huang Haowen,Liu Fengping,Liu Xuanyong
Abstract In this paper, a facile approach for preparation of AuAgS/Ag 2 S nanoclusters was developed. The unique AuAgS/Ag 2 S nanoclusters capped with biomolecules exhibit interesting excellent optical and catalytic properties. The fluorescent AuAgS/Ag 2 S nanoclusters show tunable luminescence depending on the nanocluster size. The apoptosis assay demonstrated that the AuAgS/Ag 2 S nanoclusters showed low cytotoxicity and good biocompatibility. Therefore, the nanoclusters can be used not only as a probe for labeling cells but also for their photocatalytic activity for photodegradation of organic dye. Moreover, a highly selective and sensitive assay for detection of mercury including Hg 2+ and undissociated mercury complexes was developed based on the quenching fluorescent AuAgS/Ag 2 S nanoclusters, which provides a promising approach for determining various forms of Hg in the mercury-based compounds in environment. These unique nanoclusters may have potential applications in biological labeling, sensing mercury, and photodegradation of various organic pollutants in waste water. Graphical Abstract
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高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Xin Huang,Jiawei Zhu,Chuhuang Dong,Yuqing Li,Qing Yu,Xuan Wang,Zhejie Chen,Jiabei Li,Yu Yang,Haifang Wang
Ag2S quantum dots (QDs) show superior optical properties in the NIR-II region and display significant clinical potential with favorable biocompatibility. However, inherent defects of low targeting and poor solubility necessitate practical modification methods to achieve the theranostics of Ag2S QDs. Herein, we used rolling circle amplification (RCA) techniques to obtain long single-stranded DNA containing the PD-L1 aptamer and C-rich DNA palindromic sequence. The C-rich DNA palindromic sequences can specifically chelate Ag2+ and thus serve as a template to result in biomimetic mineralization and formation of pApt-Ag2S QDs. These QDs enable specific targeting and illuminate hot tumors with high PD-L1 expression effectively, serving as excellent molecular targeted probes. In addition, due to the high NIR-II absorption of Ag2S QDs, pApt-Ag2S QDs exhibit remarkable photothermal properties. And besides, polyvalent PD-L1 aptamers can recognize PD-L1 protein and effectively block the inhibitory signal of PD-L1 on T cells, enabling efficient theranostics through the synergistic effect of photothermal therapy and immune checkpoint blocking therapy. Summary, we enhance the biological stability and antibleaching ability of Ag2S QDs using long single-stranded DNA as a template, thereby establishing a theranostic platform that specifically targets PD-L1 high-expressing inflamed tumors and demonstrates excellent performance both in vitro and in vivo.
研究领域:
生物医学工程
·
肿瘤学
·
纳米医学
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DOI
PubMed
高影响因子
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
·
2025
·
IF 3.2
Sima Ruirui,Zhong Jiaqi,Xiao Feiyan,Hao Hongshun S.,Zhang Gongliang,Hou Hongman,Bi Jingran,Yan Shuang
Given the limitations of traditional antimicrobial strategies and the pressing demand for efficient, biocompatible sterilization, photochemistry-mediated approaches have emerged as promising solutions, leveraging light-matter interactions for targeted pathogen elimination. In this study, A nanocomposite was engineered through the integration of the excellent near-infrared (NIR) photothermal properties of MXene (V₂CT x ) with biocompatible Ag 2 S nanoparticles. Subsequent to this, surface modification with polydopamine (PDA) was carried out via self-polymerization. The abundant functional groups of PDA not only enhanced biocompatibility but also amplified NIR photothermal conversion, synergizing with the intrinsic photothermal activity of V₂CT x . The Ag 2 S/V 2 CT x @PDA nanocomposite demonstrated dual functionality under 808 nm NIR light, efficiently converting photon energy into heat (reaching a temperature of 50.2 °C) and generating photocatalytic reactive oxygen species (ROS). Experimental results revealed an exceptional sterilization efficiency of 99.99% against Staphylococcus aureus ( S. aureus ) within 25 min of irradiation at a power density of 0.74 W/cm 2 using the optimal Ag 2 S-30%/V 2 CT x @PDA composite. This high-performance antibacterial effect is attributed to the synergistic combination of photothermal conversion and photocatalytic ROS generation, providing a rapid antibacterial strategy.
研究领域:
材料科学
·
纳米技术
·
光催化
·
抗菌治疗
·
生物医学工程
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DOI
PubMed
高影响因子
Nanoscale
·
2018
·Vol. 10
·期 35
·16581-16590
·
IF 7.233
Ying Zhang,Ning Zhao,Yeshan Qin,Fengxia Wu,Zhihua Xu,Tian Lan,Zhen Cheng,Ping Zhao,Hongguang Liu
Photoacoustic imaging (PAI) is a new and attractive imaging modality, and it has strong potential for application in the early detection of tumors through the use of optically absorbing targeted contrast agents. Ag2S quantum dots (QD) are a promising bionanomaterial and have attracted significant attention in the field of bioimaging. In this study, water-soluble and carboxylic acid group-coated Ag2S QDs with an ultrasmall size (∼8 nm) were synthesized via a one-step method. Their surface plasmon resonance wavelength was determined to be ∼800 nm, which is ideal for PAI. Ag2S QDs were then modified with the epidermal growth factor receptor 1 (EGFR) targeted small protein affibody ZEGFR:1907. The resulted nanoprobe, ZEGFR:1907-Ag2S QDs, was then used for targeted PAI of EGFR-overexpressed tumors. The biodistribution of the nanoprobe was further measured by ex vivo near infrared fluorescence (NIRF) imaging of the dissected tissues. The PAI results showed that ZEGFR:1907-Ag2S QDs specifically image EGFR positive tumors. The biodistribution study revealed that the nanoprobe mainly accumulated in the liver, spleen and tumors; tissue H&E staining studies indicated that the probe has good biocompatibility. Overall, the affibody-functionalized Ag2S QDs are a novel targeted nanoprobe that can be used for specific PAI of tumors.
研究领域:
生物医学工程
·
纳米技术
·
癌症研究
·
分子影像
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DOI
PubMed
高影响因子
Journal of Materials Chemistry A
·
2018
·Vol. 6
·期 17
·7959-7966
·
IF 9.931
Yuanhu Zhu,Jesús Carrete,Qing-Long Meng,Zhiwei Huang,Natalio Mingo,Peng Jiang,Xinhe Bao
Single-crystal SnSe has been reported to exhibit ultralow thermal conductivity and high thermoelectric performance. For future large-scale thermoelectric applications, however, polycrystalline SnSe would offer more advantages. Unfortunately, its thermoelectric figure of merit (ZT) is much poorer than that of single crystal. Improvements are challenging because the reduction in thermal conductivity is usually accompanied by a degradation in the power factor. Here we report how the thermal conductivity of polycrystalline SnSe can be reduced by Ag2S addition and nanostructuring while avoiding this downside. We investigated the thermoelectric properties of Ag2S-added SnSe polycrystals in the range from 300 to 773 K. We obtained a peak ZT of 0.88 in SnSe with 1% Ag2S addition (SS1), twice as high as pristine SnSe (SS). The thermal conductivity is depressed even further in a nanostructured SnSe + 0.01Ag2S sample (SS1-Nano). More importantly, at high temperature the power factor remains as high as that of the SS1 sample. Due to a minimum thermal conductivity of 0.30 W m−1 K−1, we obtained a maximum ZT of 1.13 in the SS1-Nano sample at 773 K.
研究领域:
材料科学
·
热电学
·
纳米材料
·
能量转换
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DOI
高影响因子
MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 6
·417
·
IF 5.4
Xue Huiling,Cheng Guorong,Zhang Bing,Zhan Ying,Zhao Zhihuan,Lin Jianying,Cheng Yan
Carbohydrate antigen 19 − 9 (CA19-9) is a critical biomarker in clinical oncology, as its serum concentration is closely associated with tumor detection and therapeutic monitoring. In this study, a novel colorimetric immunoassay was developed for the sensitive detection of CA19-9, utilizing g-C₃N₄/Ag₂S nanocomposites as a photoactive signal probe. The nanocomposites, synthesized via a hydrothermal method, demonstrated strong absorption in the visible region and high photocatalytic activity. In the immunoassay, antibody-functionalized magnetic beads were used to capture the target antigen, followed by labeling with detection probes based on the g-C₃N₄/Ag₂S nanocomposites. Under visible light irradiation, the nanocomposites catalyzed the oxidation of 3,3’,5,5’-tetramethylbenzidine (TMB), producing a distinct color change that was quantitatively analyzed via UV–vis spectroscopy. The method exhibited a wide linear detection range from 4.0 to 400 U/mL, with a detection limit of 1.86 U/mL, and demonstrated excellent specificity, stability, and reproducibility. Successful application to human serum samples further validated the reliability and practical utility of the assay, highlighting its promising potential for clinical cancer diagnosis and screening. Graphical abstract The alternative text for this image may have been generated using AI.
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PubMed
高影响因子
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