RSC Advances
·
2015
·Vol. 5
·期 111
·91206-91212
·
IF 3.84
Wen Long Li,Hong Yan Zou,Jing Lan,Qiang Wang,Yuan Fang Li,Cheng Zhi Huang
Hollow nanostructures have been diversely applied in many fields and efforts have been made to develop their various synthesis methodologies. Herein, homogeneous hollow Cu2−xSeyS1−y/reduced graphene oxide (rGO) nanocomposites were prepared for the first time via a facile and green aqueous chemical approach using H2S gas bubble templates as soft templates at room temperature. It is found that 2D hexagonal Cu2−xSeyS1−y nanosheets assemble around the gas–liquid interface of H2S bubbles to form hollow nanospheres on the rGO sheets, wherein rGO sheets as molecular templates play a critical role in maintaining the structural integrity of single-crystal hollow Cu2−xSeyS1−y nanospheres. Increasing the S content in the precursors, i.e., increasing the amount of H2S bubbles, both the diameter and chalcogen composition (S/Se molar ratio) of hollow Cu2−xSeyS1−y/rGO nanocomposites gradually increase. The near-infrared (NIR) localized surface plasmon resonance (LSPR) in Cu2−xSeyS1−y/rGO nanocomposites, arising from the free carriers (holes) in Cu2−xSeyS1−y, gets red shifts with increasing the S content, due to the higher carrier mass and assembly degree of Cu2−xSeyS1−y.
研究领域:
材料科学
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纳米技术
·
化学工程
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产品关联
DOI
高影响因子
ANALYST
·
2018
·Vol. 144
·期 2
·716-721
·
IF 3.864
Qing Juan Guo,Zi Yu Pan,Chen Men,Wen Yi Lv,Hong Yan Zou,Cheng Zhi Huang
A simple protocol for in situ growth of Cu2−xSe nanoparticles on graphene oxide hybrids (Cu2−xSe/rGO) acting as an efficient nanozyme is developed and thus a sensitive visual detection method of cancer cells is proposed. The Cu2−xSe/rGO heterogeneous nanomaterials have been proven to exhibit high peroxidase-like activity to catalyze the reaction of the peroxidase substrate in the presence of hydrogen peroxide. Herein, we used Cu2−xSe/rGO as a signal transducer to develop a colorimetric assay for the direct detection of cancer cells and a total of 63 cancer cells (MCF-7) can be distinguished by naked-eye observation. The results showed that the Cu2−xSe/rGO hybrids could be the promising nanozyme mimetics for potential applications in bioanalytical fields.
研究领域:
生物化学
·
纳米医学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
·
2025
·
IF 7.8
Yingjun Gao,Yinyan Guan,Jiyan Liang,Lei Yu,Yumeng Ye,Shengnan Chen,Jiayu Lv,Dehong Cheng
To address the demands for heavy metal wastewater treatment and copper resource recycling, hybrid capacitive deionization (HCDI) technology offers advantages of low energy consumption and ion selectivity. However, the practical application of HCDI is limited by the insufficient adsorption performance and stability of electrode materials. In this study, flower-like copper sulfide (CuS) was synthesized via a hydrothermal method and used as CDI electrodes, with polyvinylidene fluoride (PVDF) and polyvinyl butyral/polyvinylpyrrolidone (PVB/PVP) as binders. The effects of the two binders on electrode structure and performance were investigated, focusing on elucidating the selective adsorption mechanism of CuS as an HCDI cathode. The CuS-PVDF electrodes exhibited superior conductivity and higher Cu 2+ adsorption capacity (551.49 mg·g −1 at 1.0 V), attributed to the polar stabilization effect of rigid molecular chains and low surface energy of PVDF, which facilitated efficient utilization of CuS active sites. In contrast, the PVB-PVP binder caused shielding of active sites on CuS, and delayed charge transport due to encapsulation by flexible polymer chains. Moreover, the CuS electrodes exhibited selective adsorption of Cu 2+ in the HCDI system. The selectivity of Cu 2+ exceeded 70 % in a mixture of multiple heavy metal ions. This selective mechanism can be attributed to pK sp (CuS) = 40.3 and redox-mediated phase transformation (CuS→Cu 2 S/Cu 2 O/Cu).
研究领域:
环境工程
·
材料科学
·
电化学
·
水处理技术
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纳米技术
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2018
·
IF 6.042
Tong Yang,Chun Mei Li,Jia Hui He,Bin Chen,Yuan Fang Li,Cheng Zhi Huang
Increasing demands for the sensitive, selective, visual, conveniently solid-phase-sensing film for disease-related biomarkers, electrospun nanofibrous films (ENFFs) are a novel sensing paltform because of the high surface area ratios, networked structures, and facile functionalization. In this research, carbon dots (CDs) and quantum dots (QDs) were doped inside and electrostatically assembled on electrospun nanofibers (ENFs), affording ratiometrically dual-emitting fluoresecent films. Because of the FRET process between CDs and QDs on NFs and the strong quenching response of QDs to Cu2+, the as-prepared NFs can visually detect Cu2+ with high sensitivity and selectivity based on ratiometric fluorescent signals. By exploiting the release of numerous Cu2+ from CuO nanoparticles (NPs) under acidic conditions, a sandwich-type immunoassay with CuO NPs-labeled antibody was developed for the detection of biomarker proteins via the response of dual-emitting and FRET-based NFs to different Cu2+ concentrations. Taking advantage of the ratiometrically fluorescent property of these ENFFs as well as the Cu2+-mediated signal amplification strategy, alpha fetoprotein can be detected with high sensitivity (detection limit of 8.3 pg/mL) and selectivity. This strategy demonstrates a promising candidate with a point-of-care assay for clinical diagnostics and biomedical research.
研究领域:
生物传感器
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分析化学
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生物医学工程
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材料科学
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产品关联
DOI
PubMed
高影响因子
BIOMEDICINE & PHARMACOTHERAPY
·
2021
·
IF 6.53
Jinzhi Xu,Yan Xu,Lixin Sun,Bei Lu,Xi Yan,Zhonghao Wang,Tong Zhang
Introduction The development of multidrug resistance (MDR) is a major cause for the failure of chemotherapy, which requires the aid of nanomedicine. Methods Here in our study, a Cu 2+ based metal-organic framework (COF) was firstly developed and employed as a carrier for the delivery of glucose oxidase (GOx) and doxorubicin (Dox) (COF/GOx/Dox) for the therapy of MDR lung cancers. Results Our results showed that the GOx can catalyze glucose and produce H 2 O 2 . In the mean time, the Cu 2+ can react with GSH and then transform into Cu + , which resulted in GSH depletion. Afterwards, the produced Cu + and H 2 O 2 trigger Fenton reaction to generate ROS to damage the redox equilibrium of cancer cells. Both effects contributed to the reverse of MDR in A549/Dox cells and finally resulted in significantly enhanced in vitro/in vivo anticancer performance. Discussion The combination of glutathione depletion/reactive oxygen species elevation might be a promising strategy to enhance the efficacy of chemotherapy and reverse MDR in cancers.
研究领域:
纳米医学
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癌症治疗
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药学科学
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生物化学
✓ 已验证
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Jingyu Pang,Linan Zhou,Zhuang Liang,Tingting Li,Rui Yan,Fang Chai
The determination of heavy metal ions is critical to both human health, ecosystems, and the environment because it is a prerequisite for separating heavy metal pollutants. Herein, a ratiometric fluorescent strategy based on bimetallic AuAg nanoclusters and Si nanoparticles (AuAg-SiNPs) was constructed and achieved multivariate detection of Ag + , Cu 2+ , and Hg 2+ , simultaneously. The AuAg-SiNPs exhibited dual emission centered at 456 nm and 631 nm, with quantum yield of 23.48 %, and presented visual distinguishable signal for different ions. Notably, a smartphone visual platform was created to identify Ag + , Cu 2+ , and Hg 2+ with portable and accurate capturing and recognizing changing RGB values. The quantitative evaluation can be confirmed by various noticeable ratiometric evolution responses to three ions, the limits of detection were 1.61 nM, 49.94 nM, and 1.44 nM for Ag + , Cu 2+ , and Hg 2+ , respectively. Excellent environmental tolerance as well as reliability and practicability of AuAg-SiNPs enabled their test in real water samples. The synergistic effect of aggregation-caused quenching, static quenching effect, internal filtration effect, and fluorescence resonance energy transfer were revealed in process of detection. Ratiometric fluorescent probes offer great advantages in multiple identification of heavy metals in real sample. Smartphone-assisted detection greatly improves the effectiveness of visual on-site detection and has a promising application in real samples.
研究领域:
分析化学
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环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
Frontiers in Immunology
·
2024
·
IF 5.7
Shen Man,Dai Xianling,Ning Dongni,Xu Hanqing,Zhou Yang,Chen Gangan,Ren Zhangyin,Chen Ming,Gao Mingxuan,Bao Jing
The treatment of wound inflammation is intricately linked to the concentration of reactive oxygen species (ROS) in the wound microenvironment. Among these ROS, H2O2 serves as a critical signaling molecule and second messenger, necessitating the urgent need for its rapid real-time quantitative detection, as well as effective clearance, in the pursuit of effective wound inflammation treatment. Here, we exploited a sophisticated 3D Cu2-xSe/GO nanostructure-based nanonzymatic H2O2 electrochemical sensor, which is further decorated with evenly distributed Pt nanoparticles (Pt NPs) through electrodeposition. The obtained Cu2-xSe/GO@Pt/SPCE sensing electrode possesses a remarkable increase in specific surface derived from the three-dimensional surface constructed by GO nanosheets. Moreover, the localized surface plasma effect of the Cu2-xSe nanospheres enhances the separation of photogenerated electron-hole pairs between the interface of the Cu2-xSe NPs and the Pt NPs. This innovation enables near-infrared light-enhanced catalysis, significantly reducing the detection limit of the Cu2-xSe/GO@Pt/SPCE sensing electrode for H2O2 (from 1.45 μM to 0.53μM) under NIR light. Furthermore, this biosensor electrode enables in-situ real-time monitoring of H2O2 released by cells. The NIR-enhanced Cu2-xSe/GO@Pt/SPCE sensing electrode provide a simple-yet-effective method to achieve a detection of ROS (H2O2、-OH) with high sensitivity and efficiency. This innovation promises to revolutionize the field of wound inflammation treatment by providing clinicians with a powerful tool for accurate and rapid assessment of ROS levels, ultimately leading to improved patient outcomes.
研究领域:
生物医学工程
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分析化学
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纳米医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2015
·
IF 6.723
Tong Yang,Hong Yan Zou,Cheng Zhi Huang
A new heterogeneous catalytic composite composed of nonstoichiometric Cu2–xSe nanoparticles (NPs) with high copper deficiency and graphene oxide (GO) is prepared by coembedding in electrospun nanofibers of a poly(vinylpyrrolidone) (PVP) support, wherein GO in the nanofibers is converted into reduced GO (rGO) via heat treatment. The as-prepared composite Cu2–xSe/rGO/PVP nanofibers have demonstrated superior catalytic activity toward the reduction of a refractory organic compound by taking 4-nitrophenol (4-NP) as an example. In the presence of NaBH4, the Cu2–xSe/rGO/PVP nanofibers display a synergetic effect between Cu2–xSe and rGO in PVP nanofibers compared to their independent components or corresponding nanofibers. Furthermore, the Cu2–xSe/rGO/PVP nanofibers exhibit a favorable water-stable property via heat treatment to solidify the hydrophilic PVP matrix, which makes the composite display good reusability, stability in aqueous solution, and separability from a water medium. This work not only presents a direct, convenient, and effective approach to doping semiconductor nanomaterials into polymer nanofibers but also provides fundamental routes for further investigations about the synergetic effect between different materials based on the platform of electrospun nanofibers.
研究领域:
材料科学
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环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2025
·
IF 4.1
Yu Rao,Penghua Liang,Chenxiao Guo,Xize Chen,Minglei Cao,Chuankun Zhang,Rui Tong,Kongjun Zhu
Metal sulfide is a promising anode material for lithium-ion batteries due to their unique layered structure and high theoretical specific capacity. However, the challenge lies in enhancing electronic conductivity and cycling stability. An effective method to enhance the rate capability and cycle performance of metal sulfide materials is to construct the hybrid structure. In this paper, the interfacial engineering of multiple sulfides is explored to develop ideal lithium-ion storage anode materials. Hence, the one-step mixed hydrothermal method was used to synthesize the Cu 2-x S/ZnS hybrid structure. The synthesized Cu 2-x S/ZnS hybrid structure exhibits better lithium storage performance and higher electronic conductivity compared with the single Cu 2-x S, which has resulted from the existence of the phase interface generating the built-in electric field and boosting Li + storage properties at the phase interfaces. In comparison with the single Cu 2-x S, the results display that the Cu 2-x S/ZnS hybrid structure shows enhanced rate capability and prominent long-term cycling performance (416.9 mAh g −1 at 1 A g −1 after 1300 cycles). This strategy demonstrates that the construction of hybrid structure can improve the electronic conductivity and structure stability for other advanced anode materials.
研究领域:
材料科学
·
电化学
·
纳米技术
·
储能
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产品关联
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2019
·Vol. 26
·期 14
·14382-14392
·
IF 2.914
Yang Zhenyu,Xing Rong,Zhou Wenjun
Biochar are widely used as adsorbents/amendments for immobilizing pollutants in contaminated soils. In this study, the effects of dissolved organic matter derived from chicken manure (CMDOM) on the adsorption of ciprofloxacin (CIP) and Cu 2+ onto biochars were investigated. The FTIR spectra indicated that π-π donor-acceptor interactions between the hydroxyl groups on the biochar surface and the fluorine group connected to the benzene ring of CIP molecule was the main adsorption mechanism for CIP. CMDOM molecules interacted with the aromatic components in biochars and thus modified the surface chemical properties of biochar. The effect of CMDOM on the adsorption of CIP onto biochars showed great dependence on the distribution of solid adsorbed CMDOM and CMDOM in aqueous solutions. The solid adsorbed CMDOM facilitated CIP adsorption owing to increase the content of –OH on biochar surface, which could provide more π-electron donors and thus strengthened π-π EDA interactions between CIP and biochars. The EDS spectra showed that the ion exchange with K + was the main adsorption mechanism for Cu 2+ onto biochars, and the presence of CMDOM enhanced complexation of Cu 2+ with adsorbed CMDOM, thus increasing Cu 2+ adsorption onto biochars. These results are useful for the application of biochars to immobilize antibiotic and heavy metals in contaminated farmland soils when animal manure fertilizers is presented in soil environment.
研究领域:
环境科学
·
土壤化学
·
污染控制
✓ 已验证
DOI
PubMed
高影响因子
RSC Advances
·
2014
·Vol. 4
·期 98
·55094-55099
·
IF 3.708
Shao Qing Lie,Hong Yan Zou,Yong Chang,Cheng Zhi Huang
In this paper, negatively charged Cu2−xSe nanoparticles (NPs), stabilized by poly(styrene sulfonic acid)sodium (PSS) (PSS–Cu2−xSe NPs), were synthesized via a simple templated method, which exhibited strong localized surface plasmon resonance (LSPR) absorption in the near-infrared (NIR) region. It was found that the prepared PSS–Cu2−xSe NPs could be aggregated by lysozymes (Lys) selectively through the electrostatic interaction, since the Lys was positively charged in a neutral medium, producing a red shift of the LSPR band starting from 980 nm to 1300 nm area. With different concentrations of Lys, the LSPR band can be dynamically tuned, and the absorbance ratio of A1300/A980 has a good linear relationship with the concentration of Lys in the range of 5–100 nM, thus supplying an effective way to tune LSPR in the NIR region of semiconductors that might be applied for sensing and photothermal conversion sciences and technologies in the NIR region.
研究领域:
材料科学
·
纳米技术
·
光学
·
生物技术
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产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Lin Gu,Shuhai Ding,Junyu Zhang,Guangxin Yang,Longlong Wang,Xiaoshen Shen,Liangliang Tian,Cong Kong
Antibiotic contamination in environmental waters often occurs at low residue levels, necessitating pre-analysis concentration. To address this, we synthesized a hydrophilic molecularly imprinted resin (MIR) using melamine, urea, and formaldehyde as monomers, with oxytetracycline as the template molecule. Enhanced adsorption efficiency was achieved by doping the resin with Cu 2+ , which forms stable complexes with oxytetracycline. This Cu 2+ -doped MIR (Cu-MIR) was employed as a selective adsorbent in solid-phase extraction (SPE) to enrich four tetracycline antibiotics (TCs) from aqueous solutions. The optimized parameters for Cu-MIR in environmental water sample analysis resulted in linear detection ranges from 0.20 to 40 ng/mL, recoveries between 80.2 % to 102.4 %, relative standard deviations ≤ 9.0 %, a detection limit of 0.1 ng/mL, and the enrichment factors were between 4.79–5.13, as determined by HPLC-MS. Given its diverse adsorption mechanisms and specificity, Cu-MIR shows promise for practical applications in real-world sample analysis.
研究领域:
环境科学
·
分析化学
·
水处理
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）