AUSTRALIAN JOURNAL OF CHEMISTRY
·
2014
·Vol. 68
·期 5
·806-813
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IF 1.644
Liandong Feng,Xinyu Hu,Aming Xie,Hao Yu,Yangyang Liu,Jianfa Zhang,Wei Dong,Liandong Feng,Xinyu Hu,Aming Xie,Hao Yu,Yangyang Liu,Jianfa Zhang,Wei Dong
Polymer vesicles have attracted extensive interest for a variety of biomedical applications. Herein, novel polymer vesicles are prepared by the self-assembly of amphiphilic polyethyleneimine-g-poly(disulfide amine)-g-polyethyleneimine (PEI-g-PSSA-g-PEI) for gene delivery. To investigate the effect of hydrophobicity on transfection efficiency, a small series of PEI-g-PSSA-g-PEI were prepared under uniform conditions containing PEI fragments of the same molecular weight. The hydrophobicity of PEI-g-PSSA-g-PEI was adjusted by varying the hydrophobic content in the poly(disulfide amine) backbone and by choosing hydrophobic monomers ranging in length from C12 to C16. The hydrophobicity of polymers was also related to DNA binding affinity. Polymer vesicles obtained from the water-insoluble polymers condensed with DNA into polyplexes with sizes below 200 nm and surface charge ranging from +10 to +35 mV that were suitable for cell endocytosis. DNA polyplexes exhibited an inverted hexagonal structure, observed by transmission electron microscopy. The results of in vitro transfection demonstrate that the hydrophobic–hydrophilic balance of copolymers greatly affects their transfection properties. The top-performing polymer, II-70 %, showed improved transfection efficiency and significantly lower cytotoxicity on COS-7 cells when compared with commercial reagents polyethyleneimine (PEI 25K) and Lipofectamine 2000. These results indicate that cationic polymer vesicles with tunable hydrophobicity are promising materials for gene delivery.
研究领域:
生物医学
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基因治疗
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材料科学
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DOI
高影响因子
CERAMICS INTERNATIONAL
·
2011
·
IF 1.472
Xinghong Zhang,Yang Hou,Ping Hu,Wenbo Han,Junting Luo
The dispersion and co-dispersion behavior of ZrB 2 and SiC nanopowders in ethanol solution was studied by sedimentation test, particle size measurement and transmission electron microscope (TEM) analysis. The dispersion behavior of ZrB 2 and SiC nanopowders in ethanol solution was strongly dependent on the pH values, types and amounts of dispersant. PEI was found to be effective for the dispersion of both ZrB 2 and SiC nanopowders in ethanol solution. With the addition of PEI, the isoelectric points of ZrB 2 and SiC nanopowders in ethanol solution were at pH 10 and pH 9.5, and shift to pH 13 and pH 12.3, respectively. The stability of ZrB 2 suspension increased with the dispersant content increasing until reached 0.7 wt% and well-dispersed SiC slurry can be obtained with more than 2.5 wt% PEI. The suitable pH value for the dispersion of ZrB 2 and SiC nanopowders should be lower than 12 and 10, respectively. The well co-dispersed ZrB 2 and SiC nanocomposite powders can be achieved by using 1 wt% or more PEI below pH 10.
研究领域:
材料科学
·
化学工程
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DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Zi-han Chang,Xing-yu Long,Jing-wen Gu,Mei Zhang,Jiang-qun Zhang,Ting-mei Wang,Yan Zhang,Hui Xie,Yang Li,Pin-hua Xia
Based on the unique affinity interaction between amino (NH 2 ) and metal oxides (MOs) with phosphate groups (PO 4 3− ), herein, Fe 3+ , Fe 2+ and Sm 3+ were respectively usedas metal ion source, polyethyleneimine (PEI) as functional monomer, together with ammonia as precipitant to prepare a novel PEI-functional magnetic rare earth samarium metal oxide composite nano material (PEI/Fe 3 O 4 -Sm 2 O 3 , denoted as PFS) using a “one pot method” for the adsorption study of simulating high concentration glyphosate (GLY) in waterbodies emergency pollution. Consequently, the PFS adsorbent was characterized and analysed successfully using techniques such as SEM, TEM, EDS, BET, XRD, XPS, VSM and so on. A single-factor adsorption experiment was performed to explore how factors like the initial concentration of GLY ( C 0 ), solution pH, adsorbent dosage ( m ), and oscillation time affect PFS's adsorption of GLY. Under the optimized conditions, the adsorption of GLY by PFS could reach up to 92.3 % with a maximum saturated adsorption capacity Q max = 178.5 mg/g. Furthermore, PFS had a certain recyclability after 4 cycles adsorption-desorption of GLY. In addition, the Langmuir model ( R 2 = 0.962) could be better described the adsorption process as examined by isothermal adsorption modelling. The kinetic model fit the pseudo-secondary dynamics well ( R 2 = 0.999), and the adsorption process was spontaneous and endothermic. Besides, we the possible mechanisms of GLY adsorption by PFS were preliminarily explored, which was synergistically promoted by three main adsorption mechanisms, including electrostatic interaction and hydrogen bonding as well as covalent bonding. Morever, PEI-functional magnetic nano-Sm 2 O 3 with high affinity was first used as an adsorbent for GLY due to the synergistic interaction between Sm 2 O 3 and -HPO 3 − , NH 4 + and -HPO 3 − /-COO − . Finally, PFS was used to remove residual GLY in real world water environment (Baiyun lake, Siya river and farmland water) using a convenient and rapid magnetic separation process. The adsorption and removal of GLY in adding standard samples experiments on different substrate waters were above 95 % and could avoid the adverse effects of GLY residues on the aquatic environment. The above results indicated that PEI/Fe 3 O 4 -Sm 2 O 3 , which is a new and excellent nano adsorbent, exhibits a excellent adsorption capacity for GLY, demonstrating a large potential for practical water applications, especially for urgently water bodies polluted with high concentrations of GLY.
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DOI
高影响因子
PLANT CELL REPORTS
·
2025
·Vol. 44
·期 2
·1-15
·
IF 4.5
Li Xue,Zhou Yue,Chen Hang,Guo Zetian,Zhang Jinlian,Chen Wenli
Key message The three SDEs of C Las were expressed in citrus leaves by AuNPs-PEI mediated transient expression system, and promoted the proliferation of C Las and inhibited citrus immunity. Huanglongbing (HLB) is the most severe bacterial disease of citrus caused by Candidatus Liberibacter asiaticus ( C Las). C Las suppress host immune responses and promote infection by sec-dependent effectors (SDEs), thus insight into HLB pathogenesis is urgently needed to develop effective management strategies. In this study, we focused on the roles of SDE4310 , SDE4435 and SDE4955 in citrus. We found that the expression of SDE4310 , SDE4435 and SDE4955 to increase with increasing citrus immune genes CsPR1 , CsPR2 , CsPR5 , CsNPR1 , CsRBOHD , CsMAP3K and CsBIK1 , suggesting that the level of citrus immunity could be judged by the expression of SDE. To further explore the relationship between these three SDEs and citrus immunity, we established a transient expression system in citrus leaves, using gold nanoparticle-polyethyleneimine (AuNPs-PEI) to deliver recombinant plasmid containing SDE4310 , SDE4435 or SDE4955 respectively into citrus leaves. Results showed that SDE4310 , SDE4435 and SDE4955 were successfully expressed in citrus leaves using this transient expression system, and found that SDE4310 , SDE4435 and SDE4955 could promote the C Las proliferation by decreasing the immune gene expression of the citrus. Additionally, we used AuNPs-PEI to deliver siRNA 4310 to citrus cells, significantly reducing the expression of SDE4310 within 3 days. Although the suppression of SDE4310 expression did not inhibit the C Las proliferation, it increased the expression level of CsPR1 , CsNPR1 and CsBIK1 . This is also the first time that AuNPs-PEI has been found to be able to deliver exogenous plasmids into citrus cells and express the target protein, providing a new method for future studies on citrus HLB.
研究领域:
植物病理学
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分子生物学
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产品关联
DOI
PubMed
高影响因子
NANO
·
2024
·
IF 1
Xuecong Ma,Linlin Geng,Yu Li,Jianwen Wei,Lei Liao,Dunqiu Wang
Micro/mesoporous materials are low-cost functional materials with the potential for CO 2 adsorption. Modifying micro/mesoporous materials is significant for enhancing CO 2 adsorption and their high-value utilization. Herein, the micro/mesoporous material of composite molecular sieve ZSM-5/MCM-48 (ZM) was synthesized by a two-step crystallization method using cetyltrimethylammonium bromide as a template, tetraethyl orthosilicate as a silicon source and ZSM-5 seed as part of silicon aluminum source. Tetraethylenepentamine (TEPA) and polyethyleneimine (PEI) were used as impregnation modifiers to modify ZM with amine groups. The results showed that with the increase of amine loadings, both ZM-T60 (Impregnated with TEPA) and ZM-P60 (Impregnated with PEI) functionalized adsorbents exhibited the best adsorption capacities of 4 . 9 7 mmol ⋅ g − 1 and 3 . 2 8 mmol ⋅ g − 1 at 60, respectively, when the loading of ZM sample was 60%. The adsorption kinetic analysis showed that the adsorption of CO 2 by ZM-T60 and ZM-P60 was a chemisorption-dominated process accompanied by physical adsorption. After 10 adsorption/desorption cycles, the CO 2 adsorption capacity of ZM-T60 and ZM-P60 decreased by 8.7% and 2.6%, respectively. This work demonstrates that impregnation modification of the composite molecular sieve to achieve efficient CO 2 adsorption has practical application significance.
研究领域:
材料科学
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环境科学
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化学工程
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DOI
高影响因子
RSC Advances
·
2021
·Vol. 11
·期 53
·33202-33207
·
IF 3.361
Wen Wen,Zhongping Li,Xu Wang,Xiaoyan Du,Guangming Wen,Li Li
Metal nanoclusters (NCs) have recently emerged as a novel class of luminescent nanomaterials and held significant potential in analytical chemistry. In this work, novel polyethyleneimine stabilized palladium nanoclusters (PEI–Pd NCs) were synthesized by chemical reduction at 60 °C for 6 h, and used as a fluorescent nanosensor for the detection of oxytetracycline (OTC). The spectral characteristics, surface structure and morphology of the Pd NCs were studied. The selectivity and stability of the nanosensor were also investigated. The experimental results showed that the Pd NCs had good biocompatibility, stability and photobleaching resistance in aqueous solution. The fluorescence quenching effect showed a good linear relationship with the degree of fluorescence quenching of Pd NCs and OTC in the range of 25–440 nM, with a correlation coefficient of 0.99. The limit of detection (LOD) of the proposed nanosensor for OTC was calculated to be 22 nM. The mechanism of determination was thought to be an inner filter effect (IFE) between OTC and Pd NCs. Based on this, we have established a new nanosensing analysis method for detecting OTC.
研究领域:
分析化学
·
纳米材料科学
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DOI
高影响因子
DESALINATION
·
2024
·
IF 8.3
Peng Zhao,Fei Guo,Lingfeng Wang,Huange Zhen,Ning Zhang,Shaohua Yin,Guoli Zhou,Xuehua Ruan,Gaohong He,Xiaobin Jiang
Nanofiltration membranes with high selectivity and long-term stability for magnesium and lithium ions are crucial to efficiently enriching lithium resources in salt lake brines. Herein, a nano-gradient-structured nanofiltration membrane was fabricated, in which PEI with different molecular weights and TMC were utilized in a gradient interfacial polymerization process to construct the target active layer. Via this facile strategy, the grafting density of PEI and the amino group introduced were properly adjusted, and the pore size distribution and surface charge of the active layer were optimized. The fabricated active layer simultaneously possesses sub-nanometer pore size with a modified gradient structure and high interfacial positive charges, which can accurately screen lithium and magnesium. The successful grafting of secondary PEI and the high positive charge and continuity of the active layer have been demonstrated. After 150 hour operation (Mg/Li ratio of 50), PEI-70000/PA/PES nanofiltration membrane achieved a lithium‑magnesium separation factor (S Li/Mg ) as high as 150 while maintaining the stable permeation flux of approximately 20 L·m −2 ·h −1 ·MPa −1 , and the terminal Mg/Li ratio on the permeable side falls to 0.32, which exhibits significant potential for extracting Li from salt lake brines with high Mg/Li ratio with promising long-term stability.
研究领域:
材料科学
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环境工程
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化学工程
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DOI
高影响因子
Results in Engineering
·
2024
·
IF 6
Thi Thi Mar,Yunlong Xue,Yu Chang,Zijian Yu,Zhongxiao Du,Bing Cao,Rui Zhang
Pervaporation emerges as a promising technique for brine treatment. In this investigation, we employed a PVDF substrate layer and applied various coating solutions using a simple spray technique to produce a composite pervaporation membrane. The composite membrane's chemical structure, morphology, hydrophilicity, swelling property, surface roughness, and crosslinking conditions were thoroughly investigated. Notably, the PVDF/PEI/P(SS-MA) composite membrane exhibited outstanding desalination performance, demonstrating high salt rejection and flux of 308.7 ± 13.8 kg m −2 h −1 when subjected to a 3.5 wt% sodium chloride solution. Even at an elevated brine concentration of 20 wt%, the membrane maintained a commendable flux of 88.76 ± 5.4 kg m −2 h −1 at 72 °C. These findings underscore the efficacy of the developed composite membrane for brine desalination applications.
研究领域:
材料科学
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环境工程
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
KEY ENGINEERING MATERIALS
·
2012
·
IF 0
Yang Hou,Ping Hu,Wen Bo Han
The dispersion of SiC nanopowders in ethanol solution was studied by sedimentation test, particle size measurement and TEM analysis. The dispersion behavior of SiC nanopowders in ethanol solution was strongly dependent on the pH values, types and amounts of dispersant. PEI was found to be effective for the dispersion of SiC nanopowders in ethanol solution. With the addition of PEI, the isoelectric points of SiC nanopowders in ethanol solution were at pH 9.5, and shift to pH 12.3. The stability of SiC suspension increased with the dispersant content increasing until reached 2.5 wt% PEI. The suitable pH value for the dispersion of SiC nanopowders should lower than 10.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Hanlin Shao,Zhihao Chen,Wenzhong Yang,Xinsheng Zhu,Kegui Zhang
This work presents a novel strategy for the development of boron-selective adsorbent with synergistic adsorption effects, which is achieved by using tannic acid (TA) modified MoS 2 nanosheets to graft polyethyleneimine (PEI) onto the boron-selective resin (BSR), preparing the BSR-MoS 2 -TA/PEI composite material, and leveraging the unique interlayer structure of molybdenum disulfide (MoS 2 ) nanosheets to reduce the resistance of H 2 O transport, thereby effectively exerting the synergistic adsorption effects of BSR and PEI. The influencing factors of boron adsorption by BSR-MoS 2 -TA/PEI, such as the PEI grafting amount, adsorbent dosage, pH value, and competitive anions, were investigated. The results revealed a maximum adsorption capacity of 31.10 mg·g −1 at 35°C, which is significantly higher than that of the commercial BSR (5.9–7.2 mg·g −1 ). The fitting results of adsorption kinetics, isotherms, and thermodynamics demonstrated the characteristics of boron adsorption by BSR-MoS 2 -TA/PEI, and the adsorption process conformed to the pseudo-second-order kinetic model and the Langmuir model. Owing to the outstanding stability of the BSR substrate, BSR-MoS 2 -TA/PEI could undergo at least five cycles of adsorption. The mechanism of boron adsorption mainly encompassed complexation, electrostatic attraction, and hydrogen bond formation.
研究领域:
环境科学
·
材料科学
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DOI
高影响因子
RSC Advances
·
2020
·Vol. 10
·期 35
·20504-20514
·
IF 3.119
Jianwen Wei,Siqi Chen,Yu Li,Zeyu He,Linlin Geng,Lei Liao
To find an alternative adsorbent with high adsorption performance, KIT-6 was prepared by hydrothermal crystallization synthesis using tetraethyl orthosilicate as a silicon source and triblock copolymer P123 as a template. Then the silane coupling agent (3-chloropropyl)trimethoxysilane was first grafted onto KIT-6 mesoporous material and then the polyethyleneimine (PEI) was further grafted through the substitution reaction between amino groups and chlorine atoms. The functionalized KIT-6 was denoted as PEI/KIT-6. The samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), N2 adsorption–desorption, elemental analysis (EA), Fourier transform infrared spectroscopy (FT-IR) and thermal gravimetric analysis (TGA). The Cu2+ adsorption performance was determined by inductively coupled plasma (ICP). The results showed that the average loading of the amino groups was 3.74 mmol g−1, and the modified KIT-6 still has a stable mesoporous structure without pore blockage. With the dosage of 1 g L−1 PEI/KIT-6 and at room temperature, the optimum pH value for adsorption of 100 mg L−1 Cu2+ was 6.0. The adsorption capacity of PEI/KIT-6 for Cu2+ increased with the increase of reaction temperature, and the maximum adsorption capacity of Cu2+ was 36.43 mg g−1. The adsorption capacity tends to reach equilibrium after 120 min, and the optimum adsorption temperature was 35 °C. The pseudo-second-order kinetic model was found to be well suited for the adsorption process of Cu2+. Adsorption equilibrium data could also be described well by the classical Langmuir and Freundlich isotherm models. The adsorption tends to be the chemisorption of a monolayer.
研究领域:
材料科学
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环境科学
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DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2019
·Vol. 43
·期 24
·9696-9705
·
IF 3.069
Yashi Chen,Qing Li,Xinhong Chen,Xi Xu
Although the construction process of dual functional materials for dye and oil/water separation has been developed rapidly, the postprocess of the used separation materials themselves is still a problem owing to their non-degradation in the natural environment. Herein, novel porous membranes (PLA–PEI) are successfully prepared based on the utilization of a dip-coating technique. The adsorption isotherms and kinetics present a good correlation with Langmuir isotherms and the pseudo-second-order model, respectively. The maximum adsorption capacity of PLA–PEI for methyl orange (MO) can reach 455.10 mg g−1, which is approximately 78 times as much as that of PLA (5.82 mg g−1). In addition, the separation efficiencies of three actual oils (methylbenzene, hexamethylene and soybean oil) are all higher than 99.7%. Moreover, the obtained membranes can realize high-efficiency and simultaneous removal of MO (removal efficiency > 99.8%) and oil droplets (oil rejection > 99.7%) from mixed wastewater under a permeate flux of up to 8285 L m−2 h−1 solely driven by gravity. These results suggest that PLA–PEI is a promising and competitive candidate for water purification.
研究领域:
材料科学
·
环境科学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）