JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
·
2023
·
IF 6.1
Qin Zhang,Lijiao Fan,Wenbin Liu,Yuming Xie,Jiangang Li,Guolin Huang
The core–shell structure UiO-66-NH 2 @Ni-MOF was prepared by in-diffusion growth of 2D Ni-MOF on UiO-66-NH 2 using PVP (polyvinylpyrrolidone) as a structural guide. It was applied to the adsorption of U(VI) in aqueous solution. The materials were characterized by powder X-ray diffraction (PXRD), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and energy dispersive spectrometer (EDS). The UiO-66-NH 2 @Ni-MOF adsorption to U(VI) was investigated experimentally. The study showed that the adsorption of U(VI) onto UiO-66-NH 2 @Ni-MOF was endothermic and spontaneous. At pH 5.00 and 308 K, the adsorption capacity was 581.40 mg/g according to Langmuir model. In addition, the adsorption process can be described by the pseudo-second-order kinetic model. The adsorption capacity was kept at 83.83% of its original one after five sorption–desorption cycles, a promising indication for repetitive usage.
研究领域:
材料科学
·
环境科学
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DOI
高影响因子
Advanced Healthcare Materials
·
2021
·Vol. 10
·期 23
·2101618
·
IF 9.933
Ning Zhao,Fei-Er Yang,Cong-Ying Zhao,Shi-Wen Lv,Jin Wang,Jing-Min Liu,Shuo Wang
It is of great significance to eliminate excessive reactive oxygen species (ROS) for treating inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo 2 O 4 @PVP is constructed via a step-by-step strategy. Noticeably, the existence of oxygen vacancy in the NiCo 2 O 4 @PVP is helpful for capturing oxygenated compounds, while both redox couples of Co 3+ /Co 2+ and Ni 3+ /Ni 2+ will offer richer catalytic sites. As expected, the obtained NiCo 2 O 4 @PVP exhibits pH-dependent multiple mimic enzymatic activities. Benefiting from the introduction of polyvinylpyrrolidone (PVP), the NiCo 2 O 4 @PVP possesses good physiological stability and excellent biosafety in stomach and intestines’ environment. Meanwhile, the NiCo 2 O 4 @PVP also presents strong scavenging activities to ROS in vitro, including • O 2 − , H 2 O 2 , as well as • OH. Furthermore, a dextran sodium sulfate (DSS)-induced colitis model is established for evaluating the anti-inflammatory activity of NiCo 2 O 4 @PVP in vivo. Based on the size-mediated and charge-mediated mechanisms, the nanozyme can pass through the digestive tract and target the inflamed site for oral-administrated anti-inflammatory therapy. More interestingly, compared with the model group, the expression levels of inflammatory factors (e.g., Interleukin- 6 (IL-6), Interleukin- 1β (IL-1 β) , tumor necrosis factor-α (TNF- α ), and inducible nitric oxide synthase (iNOS)) in colon of mice show a significant decrease after nanozyme intervention, thereby inhibiting the development of IBD. In short, current work provides an alternative therapy for patients suffering from IBD.
研究领域:
纳米技术
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生物医学工程
·
药学
·
炎症研究
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DOI
PubMed
高影响因子
ACS Omega
·
2022
·
IF 4.132
Yifan Hao,Bo Peng,Chao Si,Bo Wang,Chengfeng Luo,Menghao Chen,Cheng Luo,Baijuan Gong,Zhimin Li
Malignant tumors are one of the main causes of human death. The clinical treatment of malignant tumors is usually surgery, chemotherapy, radiotherapy, and so forth. Radiotherapy, as a traditional and effective treatment method for cancer, is widely used in clinical practice, but the radiation resistance of tumor cells and the toxic side effects to normal cells are still the Achilles heel of radiotherapy. Multifunctional inorganic high-atom nanomaterials are expected to enhance the effect of tumor radiotherapy. Tungsten and bismuth, which contain elements with high atomic coefficients, have strong X-ray energy attenuation capability. We synthesized Bi2WO6 nanosheets (NSs) using a hydrothermal synthesis method and modified polyvinylpyrrolidone (PVP) on their surface to make them more stable. PVP–Bi2WO6 NSs have a variety of effects after absorbing X-rays (such as the photoelectric effect and Compton effect) and release a variety of particles such as photoelectrons, Compton electrons, auger electrons, and so forth, which can react with organic molecules or water in cells, generate a large number of free radicals, and promote cell apoptosis, thereby improving the effect of radiotherapy. We show through γ-H2AX and DCFH-DA probe analysis experiments that PVP–Bi2WO6 NSs can effectively increase cell DNA damage and reactive oxygen species formation under X-ray irradiation. Clone formation analysis showed that PVP–Bi2WO6 NSs can effectively suppress cell colony formation under X-ray irradiation. These versatile functions endow PVP–Bi2WO6 NSs with enhanced radiotherapy efficacy in animal models. In addition, PVP–Bi2WO6 NSs can also be used as contrast agents for X-ray computed tomography (CT) imaging with obvious effects. Therefore, PVP–Bi2WO6 NSs can be used as CT imaging contrast agents and tumor radiotherapy sensitizers and have potential medical applications.
研究领域:
癌症治疗
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纳米技术
·
医学成像
·
放射生物学
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DOI
PubMed
高影响因子
LUMINESCENCE
·
2026
·Vol. 41
·期 3
·e70462
·
IF 2.8
Rui Tian,Yuhui Yang,Duo Li,Jiamin Chai,Rui Zhang,Hua Yang,Haoyu Li,Xuehua Sun
Polyvinylpyrrolidone (PVP) and cysteine (Cys) double-ligand–modified copper nanoclusters (PVP-Cys CuNCs) were synthesized by a one-pot method. The addition of Cys can protect copper nanoclusters (CuNCs) more effectively and enhance its fluorescence intensity, compared with the single-ligand-modified PVP CuNCs; the double-ligand-modified PVP-Cys CuNCs showed higher fluorescence intensity and sensing ability. Based on the internal filtration and dynamic quenching effect of berberine (BBR) on PVP-Cys CuNCs, a novel, simple, and sensitive method for BBR detection has been established. This method exhibits a good linear response to BBR within the linear range of 1.09 × 10 −7 –4.26 × 10 −6 mol · L −1 , and with a limit of detection (LOD) of 3.67 × 10 −8 mol · L −1 . It has been successfully applied to the determination of BBR in practical pharmaceutical samples.
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DOI
PubMed
高影响因子
Materials
·
2024
·Vol. 17
·期 8
·1917
·
IF 3.1
Zhihong Zhang,Zhaoxia Han,Shuhui Ding,Yujing Jing,Zhenjie Wei,Dawei Zhang,Ruijin Hong,Chunxian Tao
Fluorescent carbon dots (CDs) are a new type of photoluminescent nanomaterial. Solid-state CDs usually undergo fluorescence quenching due to direct π-π* interactions and superabundant energy resonance transfer. Therefore, the preparation of solid-state fluorescent CDs is a challenge, especially the preparation of long wavelength solid-state CDs. In this research, long wavelength emission CDs were successfully synthesized by solvothermal methods, and the prepared CDs showed good hydrophobicity. The composite solid-state CDs/PVP (Polyvinyl pyrrolidone) can emit strong red fluorescence, and the quantum yield (QY) of the CDs/PVP powder reaches 18.9%. The prepared CDs/PVP solid-state powder was successfully applied to latent fingerprint detection. The results indicate that the latent fingerprints developed by CDs/PVP powder have a fine definition and high contrast visualization effect, which proves that the prepared CDs/PVP has great application potential in latent fingerprint detection. This study may provide inspiration and ideas for the design of new hydrophobic CDs.
研究领域:
材料科学
·
法医学
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DOI
PubMed
高影响因子
TALANTA
·
2020
·
IF 5.339
Zhixia Yao,Hanmeng Liu,Yaosheng Liu,Yongxing Diao,Guangxing Hu,Qifang Zhang,Zhuang Li
A novel fluorometric strategy is proposed for detecting curcumin by polyvinyl pyrrolidone-templated Cu NCs (PVP–Cu NCs) as a fluorescent probe which exhibits excitation/emission peaks at 380/510 nm. The fluorescent excitation and emission spectra of PVP-Cu NCs have a striking overlap with the UV–vis spectrum of curcumin, and the fluorescence lifetime of PVP-Cu NCs decreases after the addition of curcumin. Curcumin leads to fluorescence quenching based on fluorescence resonance energy transfer . This method allows for the determination of curcumin in the range of 0.1–10 μg mL −1 and the detection limit is 21 ng mL −1 . Furthermore, this method displays good selectivity and is successfully applied for real sample analysis.
研究领域:
分析化学
·
生物化学
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DOI
PubMed
高影响因子
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
·
2019
·Vol. 125
·期 9
·1-6
·
IF 1.784
Li Xiaoyi,Tang Zhixian,Ma Haidong,Wu Fan,Jian Ronghua
One-dimensional, single-crystalline bismuth ferrite (BiFeO 3 ) nanorods were successfully prepared by polyvinylpyrrolidone-assisted hydrothermal process. The crystal structure and morphology of the as-prepared BiFeO 3 sample were characterized by X-ray diffraction (XRD), field emission scanning electron microscope and transmission electron microscopy. The XRD analysis reveals that single-phase BiFeO 3 sample was obtained. Morphology observation shows that the as-formed BiFeO 3 nanoparticles are the shape of nanorods. The band gap of the as-prepared BiFeO 3 nanorods was identified by ultraviolet–visible diffuse reflectance spectrum. Meanwhile, the photocatalytic properties of the as-prepared BiFeO 3 nanorods were evaluated by degrading Rhodamine B. The result revealed that the as-prepared BiFeO 3 nanorods exhibit photocatalytic activity under visible light irradiation ( λ ≥ 400 nm).
研究领域:
材料科学
·
环境科学
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DOI
高影响因子
Polymers
·
2018
·Vol. 10
·期 9
·1032
·
IF 2.935
Jiazi Hou,Yihuan Wang,Hailong Xue,Yanli Dou
In this study, cellulose acetate (CA)/polyvinylpyrrolidone (PVP) core–shell nanofibers were successfully fabricated by electrospinning their homogeneous blending solution. Uniform and cylindrical nanofibers were obtained when the PVP content increased from 0 to 2 wt %. Because of the concentration gradient associated with the solvent volatilization, the composite fibers flattened when the PVP increased to 5 wt %. Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) results confirmed the existence of a hydrogen bond between the CA and PVP molecules, which enhanced the thermodynamic properties of the CA/PVP nanofibers, as shown by differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) results. To analyze the interior structure of the CA/PVP fibers, the water-soluble PVP was selectively removed by immersing the fiber membranes in deionized water. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) indicated that the PVP component, which has a low surface tension, was driven to the exterior of the fiber to form a discontinuous phase, whereas the high-content CA component inclined to form the internal continuous phase, thereby generating a core–shell structure. After the water-treatment, the CA/PVP composite fibers provided more favorable conditions for mineral crystal deposition and growth. Energy-dispersive spectroscopy (EDS) and FTIR proved that the crystal was hydroxyapatite (HAP) and that the calcium to phosphorus ratio was 1.47, which was close to the theoretical value of 1.67 in HAP. Such nanofiber membranes could be potentially applicable in bone tissue engineering.Keywords:electrospinning;core–shell;polyvinylpyrrolidone;cellulose acetate;hydroxyapatite
研究领域:
生物材料学
·
组织工程学
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DOI
PubMed
高影响因子
MACROMOLECULAR MATERIALS AND ENGINEERING
·
2018
·Vol. 303
·期 12
·1800233
·
IF 2.69
Ya Gao,Mengmeng Hou,Ruihao Yang,Lei Zhang,Zhigang Xu,Yuejun Kang,Peng Xue
Polymeric microneedles have attracted increasing interest for transdermal drug delivery owing to the unique advantages of minimal invasiveness, biocompatibility, biodegradability, and efficient drug-loading capacity. However, drug release from polymeric microneedles lacks controllability during transdermal administration. Herein, a poly(ethylene glycol) diacrylate/polyvinylpyrrolidone (PEGDA/PVP) microneedle patch with tailorable matrix constitutions is designed and fabricated using a two-step ultraviolet (UV) light-induced polymerization method. Scanning electron microscopic characterization reveals a non-uniform interior matrix of microneedles, resulting from the aggregation of PVP in the polymerized PEGDA matrix induced by UV irradiation. The fabricated microneedles are found to show sufficient mechanical strength for skin penetration and they can be removed intact after application. The controllable release property of rhodamine B (RhB)-loaded PEGDA/PVP microneedles is demonstrated in vitro by tuning the fraction of PVP content. The typical characteristics including initial burst and subsequent sustained release are attributed to the rapid dissolution of PVP and prolonged swelling of PEGDA, respectively. In addition, the microneedle insertion site can be completely recovered within 1 h on a porcine skin, indicating the minimally invasive feature of microneedle-mediated therapeutic delivery. This scalable microneedle platform may serve as a convenient and effective drug carrier for transdermal delivery of various pharmaceuticals under precise control.
研究领域:
药物递送
·
材料科学
·
生物医学工程
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DOI
高影响因子
TALANTA
·
2020
·
IF 5.339
Kai Li,Dazhi Wang,Kuipeng Zhao,Kedong Song,Junsheng Liang
Controlled printing of biodegradable and bioresorbable polymers at desired 3D scaffold is of great importance for cell growth and tissue regeneration. In this work, a novel electrohydrodynamic jet 3D printing technology with the resultant effect of electrohydrodynamic force and thermal convection was developed, and its feasibility to fabricate controllable filament composite scaffolds was verified. This method introduces an effective thermal field under the needle to simultaneously enhance the ink viscosity, jetting morphology controllability and printing structure solidify. The fabrication mechanisms of thermal convection on jetting morphology and printed structures feature were investigated through theoretical analysis and experimental characterization. Under optimized conditions, a stable and finer jet was formed; then with the use of this jet, various 3D structures were directly printed at a high aspect ratio ~30. Furthermore, the PCL/PVP composite scaffolds with the controllable filament diameter (~10 μm) which is closed to living cells were printed. Cell culture experiments showed that the printed scaffolds had excellent cell biocompatibility and facilitated cellular proliferation in vitro. It is a great potential that the developed electrohydrodynamic jet 3D printing technology might provide a novel approach to directly print composite synthetic biopolymers into flexibly scale structures for tissue engineering applications.
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DOI
PubMed
高影响因子
NANOTECHNOLOGY
·
2018
·Vol. 30
·期 6
·065102
·
IF 3.404
Oyawale Adetunji Moses,Malik Ihsanullah Khan,Qi Fang,Liu Qin,Zia ur Rehman,Youkui Zhang,Cao Deng Feng,Yinchu Ma,XinFeng Tang,Chuanqiang Wu,Mukhtar Lawan Adam,Dake Huang,Hang Liu,Li Song
Transition metal dichalogenides (TMDCs) with unique layered structures hold promising potential as transducers for photothermal therapy. However, the low photothermal conversion efficiency and poor stability in some cases limit their practical applications. Herein, we demonstrate the fabrication of ultrathin homogeneous hybridized TMDC nanosheets and their use for highly efficient photothermal tumor ablation. In particular, the nanosheets were composed of metallic WSe2 intercalated with polyvinylpyrrolidone (PVP), which was facilely prepared through a solvothermal process from the mixture of selenourea crystals, WCl6 powder along with PVP polymeric nanogel. Our characterizations revealed that the obtained nanosheets exhibited excellent photothermal conversion efficiency, therapeutic demonstration with improved biocompatibility and physiological stability attributing to the combined merits of metallic phase of WSe2 and hydrophilic PVP insertion. Both the histological analysis of vital organs and in vitro/in vivo tests confirmed the nanosheets as actively effective and biologically safe in this phototherapeutic technique. Findings from this non-invasive experiment clearly emphasize the explorable therapeutic efficacy of the layered-based hybrid agents in future cancer treatment planning procedures.
研究领域:
纳米医学
·
癌症治疗
·
材料科学
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产品关联
DOI
PubMed
高影响因子
OPTICAL MATERIALS
·
2023
·
IF 3.9
Zhihao Zhang,Md All Amin Newton,Xue Yang,Binjie Xin
In this study, a novel red fluorescent materials were prepared by incorporating Eu/PVP/TPPO complexes into PAN substrates. An Eu/PVP/TPPO complex was synthesized by introducing polyvinylpyrrolidone (PVP) into a mixture of europium (Eu) and triphenylphosphine oxide (TPPO). Using a spin-coating technique, highly efficient and thermally stable Eu/PVP/TPPO/polyacrylonitrile (PAN) fluorescent films were prepared. The molecular interactions , surface morphology , functional groups, and elements of the Eu/PVP/TPPO/PAN fluorescent films were characterized by FT-IR, SEM, UV–Vis, and EDS analysis. The thermal stability, fluorescent properties, and chromaticity of the films were also systematically investigated. The results showed that the Eu/PVP/TPPO complex could disperse uniformly in the substrate, and the fluorescent films could emit homogeneous red light. Furthermore, the Eu/PVP/TPPO/PAN fluorescent films had a strong synergistic effect, which increased the fluorescence intensity and produced a purer red light. Based on these findings, a new type of redlight LED device was fabricated by one-step method. Due to its outstanding properties, this film has great potential in the next generation of lighting and display applications.
研究领域:
材料科学
·
光学工程
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）