APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
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2018
·Vol. 124
·期 6
·1-8
·
IF 1.604
Lin Changwei,Tang Yu,Song Jun,Han Lei,Yu Jingbo,Lu Anxian
In the present study, series of garnet-type Li 6.75+ x La 3− x Sr
x
Zr 1.75 Nb 0.25 O 12 solid electrolytes [LLSZN with various Sr contents ( x = 0.05–0.25)] have been prepared via conventional solid-state method. The effects of Sr contents on their phase structure and ionic conductivity have been systematically investigated on the combined measurements of X-ray diffraction and scanning electron microscopy and alter current impedance spectroscopy. Our results reveal that a phase transition from tetragonal to cubic structure occurs when both Sr and Nb elements is introduced, and such a cubic structure can be stable over the whole Sr contents variation, which is suggested to provide a beneficial impact on the performance of LLSZN. Accordingly, both relative density and total ionic conductivity exhibit a favorable tendency of increasing first and then decreasing with increased Sr contents, wherein a peak value at 93.46% and 5.09 × 10 −4 S cm −1 , respectively, can be well achieved. Particularly, the maximum ionic conductivity is almost twice that of the compared sample (2.93 × 10 −4 S cm −1 ), and possess the minimum activation energy ~ 0.30 eV. Such a modification method, featured with higher efficiency and lower cost, is expected to be helpful for the development of solid electrolyte.
研究领域:
材料科学
·
电化学
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DOI
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Jingjing Liu,Bi Zhou,Yuliang Guo,Amin Zhang,Kai Yang,Yu He,Jianbo Wang,Yingsheng Cheng,Daxiang Cui
Cardiovascular and cerebrovascular diseases induced by atherosclerosis (AS) have become the dominant cause of disability and mortality throughout the world. The typical early pathological process of AS involves the activation of inflammatory macrophages in the vulnerable plaque. In this work, we first employed chitosan-coated carbon nanocages (CS-CNCs) as nanocarriers to load Chlorin e6 (Ce6) and then linked dextran sulfate (DS) to the outermost layer by electrostatic adsorption to create a multifunctional therapeutic nanoplatform, CS-CNCs@Ce6/DS. The DS of the nanoplatform can recognize and bind to the type A scavenger receptor (SR-A), which is expressed only on the activated macrophages of the arterial plaque, so the proposed nanoplatform selectively targets these macrophages and accumulates there. Furthermore, DS can competitively inhibit cellular endocytosis of oxidized low-density lipoproteins via blocking of SR-A. The rapid photothermal conversion capability of CS-CNCs enables efficient therapeutic delivery during photothermal therapy (PTT). Interestingly, near-infrared-accelerated drug release induced by initial 808-nm laser irradiation was observed, thus enhancing the Ce6 concentration in the atherosclerotic plaque area and the efficiency of photodynamic therapy (PDT). Sequential photothermal/photodynamic ablation of the activated macrophages reduced pro-inflammatory cytokine secretion and alleviated the proliferation and migration of smooth muscle cells. These finally resulted in the stabilization and shrinkage of atherosclerotic plaques, further inhibiting the development and exacerbation of AS. Therefore, this work achieved a “1 + 1 greater than 2” effect by providing a novel approach to the treatment of atherosclerotic plaques, which is promising for the prevention of AS-related diseases.
研究领域:
心血管疾病
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纳米技术
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治疗递送系统
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炎症
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生物医学工程
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DOI
PubMed
高影响因子
International Journal of Nanomedicine
·
2018
·
IF 4.37
Yong Huang,Xue Shen,Haixia Qiao,Hao Yang,Xuejiao Zhang,Yiyao Liu,Hejie Yang
Background Two frequent problems associated with titanium (Ti) surfaces of bone/dental implants are their corrosion and lack of native tissue integration.Methods Here, we present an anodization-hydrothermal method for coating Ti surfaces with a layer of silicon (Si)- and strontium (Sr)-loaded titania nanotubes (TNs). The Ti surfaces coated with such a layer (Si–Sr-TNs) were characterized with different techniques.Results The results indicate that the Si4+ and Sr2+ ions were evenly incorporated into the TNs and that the Si–Sr-TN layer provides good protection against corrosive media like simulated body fluid. The excellent cytocompatibility of the coating was confirmed in vitro by the significant growth and differentiation of MC3T3-E1 osteoblastic cells.Conclusion Being easily and economically fabricated, the Si–Sr-TN surfaces may find their niche in clinical applications, thanks to their excellent biological activity and corrosion resistance.
研究领域:
生物材料学
·
医学工程
·
组织工程
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DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2015
·
IF 2.999
Renping Cao,Yunling Cao,Ting Fu,Shenhua Jiang,Wensheng Li,Zhiyang Luo,Jingwei Fu
Novel red phosphors R 3 P 4 O 13 :Bi 2+ (R = Sr and Ba) are synthesized by solid state reaction method in air, and their crystal structures and fluorescence properties are characterized. The excitation bands peaking at ∼440 nm match with the blue LED chip, and their red emission band peaking at ∼658 and 686 nm within the range 580–800 nm owing to 2 P 3/2 (1) → 2 P 1/2 the transition of Bi 2+ ions can be observed, respectively. The relation between Bi 2+ doping concentration and emission intensity is discussed and the optimal Bi 2+ ion doping concentration is ∼3.0 mol%. Decay curves and time-resolved spectra confirm that R 3 P 4 O 13 :Bi 2+ (R = Sr and Ba) phosphors have only single Bi 2+ center. The luminous mechanism is explained by energy level diagram of Bi 2+ . The luminescence properties indicate that R 3 P 4 O 13 :Bi 2+ (R = Sr and Ba) phosphors have a potential to be used as red emitting phosphor candidate for white LEDs based on ∼440 nm blue LED chip.
研究领域:
材料科学
·
光学
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DOI
高影响因子
MATERIALS CHARACTERIZATION
·
2021
·
IF 4.342
Kangkang Yuan,Qing Cui,Jie Li,Xiaotong Jin,Chengshun Li,Xingxiang Ji,Zhongjian Tian,Xinqiang Wang
A compositionally complex (Ca, Sr, Ba)ZrO 3 (CC-CSBZ) fibrous membrane with perovskite structure was successfully prepared via a simple electrospinning method. The formation, phase transformation and microstructure evolution of CC-CSBZ fibers were fully discussed. X-ray diffraction, Raman spectra and transmission electron microscopy analyses confirmed the formation and phase transformation of CC-CSBZ solid solution at high temperatures. Scanning electron microscopy results indicated that a slower grain growth rate and more stable high-temperature microstructure were achieved for CC-CSBZ fibers compared with previous BaZrO 3 and CaZrO 3 fibers. CC-CSBZ fibrous membrane also exhibited excellent flexibility at 1000 °C and high thermal stability at 1200 °C. Furthermore, an average near infrared reflectivity of 98% at least at room temperature was obtained for CC-CSBZ fibrous membrane heat-treated from 800 to 1400 °C. For the slow grain growth rate, excellent high-temperature stability and near infrared reflectance, CC-CSBZ fibrous membrane would be a promising and novel ceramic fiber product for high temperature applications.
研究领域:
材料科学
·
陶瓷工程
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DOI
高影响因子
SOLID STATE SCIENCES
·
2023
·
IF 3.5
Dong Gao,Fuqiang Chen,Hongping Wu,Zhanggui Hu,Jiyang Wang,Yicheng Wu,Hongwei Yu,P Shiv Halasyamani
Heteroanionic materials are of current research interest owing to their varied structural chemistry and properties. Recently, a number of heteroanionic materials have been synthesized that can be used for water splitting, battery materials, thermoelectrics , and nonlinear optical applications. Birefringent heteroanionic materials are still rarely researched. Herein, we report a series of new oxychalcogenides, AGe 2 O 4 Q (A = Ba, Sr; Q = S, Se), that are synthesized by solid-state reactions in fused silica tubes with their structures determined by single-crystal X-ray diffraction. Optical property measurements show that AGe 2 O 4 Q (A = Ba, Sr; Q = S, Se) exhibit large birefringences , 0.13–0.19 @ 1064 nm. These are one-order of magnitude larger than their single-anionic homologue, BaGe 2 O 5 - 0.03 @ 1064 nm. This suggests that constructing heteroanions through using chalcogenides to partially substitute O in tetrahedral foundation building units (FBUs) is a viable method for designing new birefringent materials. Furthermore, the crystal structures, UV–vis–NIR diffuse reflectance spectra, infrared and Raman spectra as well as the first-principles calculations for AGe 2 O 4 Q (A = Ba, Sr; Q = S, Se) are also reported.
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高影响因子
Advanced Science
·
2024
·
IF 14.3
Jin Liu,Yilin Shi,Yajun Zhao,Yue Liu,Xiaoru Yang,Kai Li,Weiwei Zhao,Jianmin Han,Jianhua Li,Shaohua Ge
Surface modification is an important approach to improve osseointegration of the endosseous implants, however it is still desirable to develop a facile yet efficient coating strategy. Herein, a metal–phenolic network (MPN) is proposed as a multifunctional nanocoating on titanium (Ti) implants for enhanced osseointegration through early immunomodulation. With tannic acid (TA) and Sr 2+ self-assembled on Ti substrates, the MPN coatings provided a bioactive interface, which can facilitate the initial adhesion and recruitment of bone marrow mesenchymal stem cells (BMSCs) and polarize macrophage toward M2 phenotype. Furthermore, the TA-Sr coatings accelerated the osteogenic differentiation of BMSCs. In vivo evaluations further confirmed the enhanced osseointegration of TA-Sr modified implants via generating a favorable osteoimmune microenvironment. In general, these results suggest that TA-Sr MPN nanocoating is a promising strategy for achieving better and faster osseointegration of bone implants, which can be easily utilized in future clinical applications.
研究领域:
生物材料
·
组织工程
·
免疫学
·
骨科
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DOI
PubMed
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
·
2021
·
IF 7.328
Yujie Zhang,Chuanfeng An,Yang Zhang,Haoyue Zhang,Abdullah Faqeer Mohammad,Qiao Li,Weijian Liu,Fei Shao,Jiayi Sui,Changle Ren,Kai Sun,Fang Cheng,Jia Liu,Huanan Wang
Cell microenvironment is a collection of dynamic biochemical and biophysical cues which functions as the key factor in determining cell behavior. Encapsulating single cell into micrometer-scale hydrogels which mimics the cell microenvironment can be used for single cell analysis, cell therapies, and tissue engineering. Here, we developed a microfluidics-based platform to engineer the niche environment at single cell level using alginate microgels crosslinked by different metal ions to regulate stem cell behavior for bone regeneration. Specifically, we revealed that Ca 2+ in the engineered microenvironment promoted osteogenic differentiation of encapsulated stem cells and substantially accelerated the matrix mineralization compared to Sr 2+ in vitro . However, the superior osteoinductive capacity of Ca 2+ compared with Sr 2+ led to comparable bone healing in a rat bone defect model. This attributed to Sr 2+ in microgels to inhibit the osteoclast activity and bone resorption after implantation. In summary, the present study demonstrates metal ions as a critical factor in the environmental cues to affect cell behavior and influence the efficacy of stem cell-based therapy in tissue regeneration, and provides new insights to engineer an expecting microenvironment for regenerative medicine.
研究领域:
组织工程
·
干细胞生物学
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再生医学
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生物医学工程
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DOI
PubMed
高影响因子
RSC Advances
·
2024
·Vol. 14
·期 17
·11849-11861
·
IF 3.9
Zanji Rong,Weihua Shen,Yunjin Fang
In this work, the effect of alkaline earth metal modification on the catalytic performance of activated carbon supported Cu was investigated. The experimental results showed that the introduction of Ca and Sr improved the selectivity of methyl glycolate (MG) during hydrogenation of dimethyl oxalate (DMO) in gas phase. The optimal loading amount of Ca was 0.1 wt%, and under the optimal conditions (temperature 240 °C, pressure 2 MPa, hydrogen–ester ratio of 80, feedstock 15% DMO methanol solution, and WLHSVDMO = 0.9 h−1) the selectivity of MG was as high as 94%, and the conversion of DMO was 97%. The optimal loading of Sr was 0.2 wt% with MG selectivity up to 89% and DMO conversion of 98%. The results of catalyst characterization showed that both Ca and Sr modifications were beneficial to further reduce the particle size of Cu, improve the dispersion of Cu, increase the basicity of the catalyst, and improve the stable presence of Cu+ during the reaction process. Cu+ was beneficial to the stabilization of the MG species, in which Cu+ accounted for more in the Ca-modified catalysts Cu+/(Cu+ + Cu0) = 0.65, and in the Sr-modified ones Cu+/(Cu+ + Cu0) = 0.51. Therefore, both Ca and Sr modified catalysts showed improvement in the selectivity of MG.
研究领域:
催化化学
·
材料科学
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DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Bo An,Qin Zhang,Ke Wang,Jiaqi Yang,Dongxing Song,Huijuan Su
The Gd 0.1 Ce 0.9- x Sr x O 2-δ ( x = 0, 0.01, 0.04, 0.07) electrolytes were synthesized via the citric acid-EDTA combustion method as electrolyte materials for intermediate-temperature solid oxide fuel cells (IT-SOFCs), aiming to enhance ionic conductivity and mechanical stability of SOFCs at intermediate-to-high temperatures. Sr²⁺ doping improved electrolyte densification, increased grain volume, and reduced grain boundary density, thereby enhancing the dielectric constant. These modifications decreased both intragrain and grain boundary resistances and facilitated oxygen ion migration. At 500°C, the optimized Gd 0.1 Ce 0.86 Sr 0.04 O 2-δ exhibited a 6.4-fold increase in ionic conductivity and a 50% reduction in activation energy compared to Gd 0.1 Ce 0.9 O 1.95 . This enhancement was partially attributed to the improved scavenging coefficient of Gd 0.1 Ce 0.86 Sr 0.04 O 2-δ , whose blocking factor decreased by approximately 43% relative to Gd 0.1 Ce 0.9 O 1.95 . Dielectric property analysis elucidated the contribution of Gd-Sr synergistic effects to interfacial polarization.In terms of mechanical properties, the 4GSDC sample demonstrated a 13.5% increase in Vickers hardness, 69.7% improvement in fracture toughness, and 24.91% enhancement in flexural strength compared to GDC. At 750°C, single cells with the 4GSDC electrolyte achieved a power density of 1100 mW/cm², representing a 55.4% improvement over GDC. Density functional theory (DFT) calculations revealed that Sr²⁺ incorporation effectively reduced binding energy and migration barriers. Therefore, Sr-Gd co-doping can be regarded as an effective strategy to enhance the performance of ceria-based electrolytes in IT-SOFCs.
研究领域:
材料科学
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能源技术
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电化学
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固体氧化物燃料电池
·
陶瓷材料
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DOI
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2025
·Vol. 108
·期 8
·e20595
·
IF 3.8
Qian Qiu,Haoyu Wang,Yanghao Xu,Xinyu Chen,Xinyu Liu,Yuan Zhou,Zeyu Lv,Jinfeng Sun,Shaofei Zhang,Haibo Zhang,Abdul Manan,Gang Liu,Yan Yan
Piezoelectric ceramics, renowned for their ability to interconvert mechanical strain/stress and electrical signals, are widely utilized in diverse fields, such as electronic communications, aerospace, and national defense. Their appeal lies in their rapid response, precise motion control, and low power consumption, making them indispensable in advanced electromechanical systems. Bismuth sodium titanate (BNT)-based ceramic materials exhibit excellent strain performance and piezoelectric response, making them highly promising for applications in actuators and transducers. In this study, the piezoelectric ceramic system of (0.93− x )Bi 0.5 Na 0.5 TiO 3 −0.07BaTiO 3 − x Sr(Sn 0.5 Ta 0.4 )O 3 ( x = 0–0.02, BNBT− x SST) were synthesized using the conventional solid-state reaction method. Through a combination of composition design and phase boundary engineering, the microstructure of the ceramics is modified, and a systematic analysis of the relationship between the electrical properties and the microstructure is conducted. The results indicate that the addition of SST reduces the domain size and influences the phase evolution, gradually transitioning the ceramics from non-ergodic relaxor (NR) to ergodic relaxor (ER) state. Among all the compositions, BNBT−0.010SST exhibits outstanding performance. At a relatively low driving electric field ( E = 50 kV/cm), the maximum piezoelectric strain coefficient ( d 33 * ) reaches 632 pm/V, while under a relatively higher driving electric field ( E = 80 kV/cm), a strain response of 0.42% is achieved. This exceptional performance is believed to result from a reversible phase transition between the FE and ER states driven by the electric field. Additionally, the strain of this ceramic remains stable at over 90% within the temperature range of 30°C–100°C, demonstrating outstanding temperature-insensitive properties. At the same time, compared to other BNT-based ceramic systems, the hysteresis at room temperature has been effectively reduced, remaining below 47%. Therefore, this study provides valuable insights for improving the strain performance of NBT-based lead-free piezoelectric ceramics, offering greater possibilities for their application in piezoelectric devices.
研究领域:
材料科学
·
陶瓷与复合材料
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压电材料
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功能材料
·
固态物理
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产品关联
DOI
高影响因子
Materials Science and Engineering B-Advanced Functional Solid-State Materials
·
2025
·
IF 4.6
Zixuan Tian,Jialing Jiang,Lei Wang,Songtao Dong,Jing Luan,Hongbo Ju
BiCuSeO has attracted significant interest in the field of thermoelectric materials due to its layered crystalline structure, along with advantages such as abundant elemental availability, low thermal conductivity, and outstanding thermal stability. However, the inherently low electrical conductivity of BiCuSeOlimiting overall thermoelectricperformance. To address this, as an effective strategy to enhance thermoelectric performance, BiCuSeO was subjected to tri-element co-doping. Bi 1−3x (CaSrBa) x CuSeO (x = 0.0, 0.02, 0.03, 0.04, and 0.05) ceramics were synthesized using an advanced fabrication process that combined high-energy ball milling with hot-press sintering techniques. Substituting Ca 2+ , Sr 2+ , and Ba 2+ at the Bi 3+ sites effectively optimized the carrier concentration, increased the effective mass, and significantly enhanced the electrical conductivity from 9.67 to 91.55 S cm −1 . Notably, the power factor of the Bi 0.88 (CaSrBa) 0.04 CuSeO sample reached 476.54 μW m −1 K −2 at 323 K. and electrical conductivity. Simultaneously, the introduction of lattice defects through co-doping considerably enhanced phonon scattering, reducing the lattice thermal conductivity to 0.342 W m −1 K −1 for Bi 0.85 (CaSrBa) 0.05 CuSeO, compared with 0.447 W m −1 K −1 for the pristine sample. Consequently, a maximum dimensionless figure of merit ( ZT ) of 0.65 was achieved at 773 K for Bi 0.88 (CaSrBa) 0.04 CuSeO. These findings provide valuable insights into improving the thermoelectric performance of BiCuSeO-based materials through multi-element co-doping.
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DOI
高影响因子
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