Advanced Science
·
2025
·
IF 14.1
Haomiao Bai,Sujun Ding,Yanfei Dai,Jiefu Liu,Huangjing Chen,Wei Feng,Dehong Yu,Yu Chen,Xuejun Ni
Piezoelectric semiconductor nanomaterials have attracted considerable interest in piezocatalytic tumor treatment. However, piezocatalytic therapy encounters obstacles such as suboptimal piezoelectric responses, rapid electron-hole recombination, inefficient energy harvesting, and the complexities of the tumor microenvironment. In this study, sulfur vacancy-engineered cobalt (Co) single-atom doped molybdenum disulfide (SA-Co@MoS 2 ) nanoflowers are strategically designed, which exhibit enhanced piezoelectric effects. Specifically, the introduction of Co single atom not only induces lattice distortion and out-of-plane polarization but also leads to the formation of numerous sulfur vacancies. These changes collectively narrow the intrinsic bandgap of the material, facilitating effective separation and migration of charge carriers, and enabling efficient production of reactive oxygen species under ultrasound stimulation. Additionally, the SA-Co@MoS 2 nanoflowers demonstrate improved enzymatic activity and exhibit glutathione depletion capabilities attributed to the mixed valence states of Co, intensifying oxidative stress in tumor cells, and leading to cell cycle arrest and apoptosis, while the inactivation of glutathione peroxidase 4 induces ferroptosis. Both in vitro and in vivo results indicate that SA-Co@MoS 2 nanoflowers can significantly eliminate tumor cells. This study offers valuable insights into the exploration of single-atom doping-enhanced piezoelectric sonosensitizers for cancer treatment, potentially paving the way for advancements in the field of piezocatalytic synergistic enzyodynamic therapy.
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高影响因子
TALANTA
·
2024
·
IF 5.6
Cuiyun Kou,Haiguo Hu,Ying Tang,Yiyu Luo,Chenggong Han,Yu Bao,Zhinan Guo,Li Niu
Ag + , as a good bactericidal reagent, has been extensively used to prevent the growth and spread of bacteria and viruses. However, overcommit of Ag + would leave residues in environments, which is toxic to the human body even under minimal exposure. In this case, a fast and high selective sensing method based on field effect transistors (FET) has been proposed for monitoring Ag + in aqueous solutions. Through coordination interaction, Ag + could be spontaneously adsorbed on the surface of the sensing material MoS 2 and affect its electronic carrier transport behavior. The MoS 2 -based FET sensor show outstanding sensing performance to Ag + including short response time (60 s), good linear relationship (R 2 = 0.97), low detection limit (10 −10 mol/L) and high selectivity, which could meet the permissible criterion of Ag + in drinking water by the World Health Organization (0.93 × 10 −6 mol/L). This study will promote the application of FET sensors in environmental analysis, and provide important guidance to realize rapid, on-site or in-situ monitoring of heavy metals in aqueous solutions.
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高影响因子
IEEE TRANSACTIONS ON ELECTRON DEVICES
·
2024
·Vol. 71
·期 10
·6336-6342
·
IF 2.9
Jianwen Song,Lei Liang,Xiao Yong,Xinpeng Chen,Shibu Zhu,Zuquan Wu
In this article, molybdenum disulfide (MoS
2
)/cellulose nanocrystal (CNC) nanocomposites are coated on silver electrodes of the quartz crystal microbalance (QCM) by the drop-coating method for humidity sensing. The performance of QCM humidity sensors of MoS
2
, CNC, and MoS
2
/CNC thin films is investigated in the relative humidity (RH) range of 11.31%–97.59%. The experimental results reveal that MoS
2
/CNC humidity sensor has high sensitivity (ca. 36.03 Hz/%RH), which is higher than CNC (ca. 1.25 times) and MoS
2
(ca. 2.5 times). Meanwhile, the sensor has excellent repeatability, high stability, and low humidity hysteresis (ca. 3.3%RH). Moreover, the Langmuir isotherm adsorption model is also used to investigate the humidity-sensitive mechanism of MoS
2
/CNC humidity sensors. In addition, MoS
2
/CNC humidity sensor can be well applicable for respiration monitoring which has good application prospect.
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SENSORS
·
2025
·Vol. 25
·期 3
·623
·
IF 3.5
Yuzhen Wang,Ningna Shi,Xiaoyue Kang,Qiliang Pan,Maozhong Tian,Yanfeng Wang,Yunfeng Bai
A sensitive and specific competitive electrochemical immunosensor for the detection of Hg (II) using a modified electrode based on molybdenum disulfide/reduced graphene oxide/gold (MoS2/rGO/Au) nanocomposites was developed in this study. The nanocomposites were characterized and assembled with an antibody against Hg (II) for the immunosensor, demonstrating good electrical activity, high affinity and high specificity. Free Hg (II) in a solution can be measured by the competitive reaction of the Hg element in the sample and the antigen with the antibody fixed on the electrode. A differential pulse voltammetry (DPV) method was used, and the competitive current changed in accordance with the concentration of Hg (II). Under optimal conditions, the sensor showed a linear relationship from 0.1 to 600 ng/mL, and the limit of detection (LOD) was 63 pg/mL. The proposed immunosensor showed an acceptable recovery from 98.4% to 100.3% in spiked samples. Satisfactory stability and reproducibility were obtained. Competitive species, including Zn (II), Mg (II), Al (III), Cu (II), Pb (II), Ba (II), Cd (II), Ag (I), MNA, CH3Hg (I) and CH3Hg-MNA, were selected and applied according to the procedure of the assay, and their significantly different response compared to Hg (II) indicated that the assay displayed not only high sensitivity but also high selectivity. This immunosensor offers a useful model for the detection of Hg (II).
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Mingming Chang,Ruiru Yang,Xiaojing Lai,Xinzhi Wang,Aike Liu,Jing Jiang
Exploiting efficient solar evaporators with photothermic-catalytic bifunctionality has been identified as a reliable strategy for alleviating pollutant enrichment when using organic wastewater as a water source to produce freshwater during solar evaporation. Herein, a new boron-doped molybdenum disulfide (B-MoS 2 ) is introduced as a photoabsorber and catalytic unit to create bifunctional solar evaporator, which demonstrates synergistic process of photothermal conversion and catalytic activation to achieve simultaneous freshwater production and antibiotic destruction in tetracycline (TC)-containing wastewater with peroxymonosulfate (PMS). The B-MoS 2 evaporator displays a superior evaporation rate of ∼ 2.31 kg·m −2 ·h −1 and a high degradation efficiency of 80.7 % within one hour for TC solution under 1-sun irradiation. The combined radical/nonradical pathways are found to dominate the TC degradation, and efficient detoxification is realized over the PMS-coupled B-MoS 2 evaporator. This work provides new avenues to produce freshwater from wastewater sources with the alleviated pollutant enrichment during solar evaporation.
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TALANTA
·
2024
·
IF 5.6
Sen Wang,Zhongjun Yan,Fei Shen,Lihui Du,Guanglei Li,Qian Yang,Qiuhui Hu
Endotoxins , also known as lipopolysaccharides (LPS), are present within the cell walls of Gram-negative bacteria and are released upon cellular death, which can pose a significant risk to human and animal health. Due to the minimal amount of endotoxin required to trigger an inflammatory response in human body, the demand for sensitive methods with low endotoxin detection limits is essential necessary. This paper presents a straightforward aptamer sensor which can enhance the conductivity and specific surface area of molybdenum disulfide (MoS 2 ) by incorporating carboxylated multi-walled carbon nanotubes (MWCNTs-COOH) and polyaniline (PANI). Doping with gold nanoparticles (AuNPs) improves biocompatibility and sensitivity while providing binding sites for thiolated endotoxin-binding aptamers (LBA). This biosensor achieved a remarkable detection limit as low as 0.5 fg mL −1 , enabling trace-level identification of LPS. It also exhibits excellent repeatability, selectivity , and stability, facilitating rapid and accurate LPS detection. Moreover, this method demonstrates high recovery rates and specificity for LPS analysis in food samples, showcasing its promising application prospects in trace-level LPS detection within the food industry.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Hongxiang Shu,Hankui Sang,Congming Tang,Kai Ma,Xinli Li
Solar-driven interfacial evaporation for seawater and other wastewater is widely viewed as green, environmental technology to generate clean water. Herein, the sulfur vacancy-rich MoS 2 -sodium alginate-filter cotton aerogel evaporator was designed to purify seawater, heavy metal wastewater and dyestuff wastewater for production of clean water. From analysis of XPS spectra, 2H-MoS 2 dominates in B MoS 2 (bulk MoS 2 ) while 1 T-MoS 2 becomes a major phase in SS MoS 2 (ultrathin and sulfur vacancy-rich MoS 2 ). EPR measurement reveals that SS MoS 2 possesses far richer sulfur vacancies than B MoS 2 . SS MoS 2 displays a stronger broadband absorption ability and lower reflectance than B MoS 2 . As a result, SS MoS 2 -based evaporator offered more excellent water evaporation performance than B MoS 2 -based evaporator. Under irradiation of 1 sun, the SS MoS 2 -based evaporator achieves a high evaporation rate of 2.03 kg m −2 h −1 which is higher than the B MoS 2 -based evaporator with 1.58 kg m −2 h −1 , demonstrating that sulfur vacancy has an enhanced effect for photothermal conversion. The SS MoS 2 -based evaporator also displays an excellent evaporation rate of seawater, close to pure water. Besides, this evaporator shows an excellent durability for seawater desalination, and maintains a self-cleaning effect. In addition, this evaporator offers an excellent performance for purifying heavy metal wastewater, in which the heavy metal ionic concentration of the purified water is far lower than drinking water stated by the standard of World Health Organization. Encouragingly, this evaporator can also purify dyestuff wastewater to generate clean water by evaporation, adsorption and photocatalysis. This work presents a novel strategy for desalination of seawater and purification of heavy metal wastewater and dyestuff wastewater to generate clean water by integrating the defected MoS 2 into sodium alginate aerogel evaporator.
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2D Materials
·
2021
·Vol. 8
·期 3
·035049
·
IF 7.103
Mahsa Jalali,Zhaoli Gao,Ye Yu,Roozbeh Siavash Moakhar,Yao Ding,Minghao Zhuang,Nan Zhou,Tobias König,Andreas Fery,Sara Mahshid,Zhengtang Luo
Enhancing photoluminescence (PL) of semiconducting 2D materials is proven essential for many applications related to optoelectronics and sensing. Here, we demonstrate synergistic PL enhancement in 2D materials by incorporating silver plasmonic nanodiscs in defect-induced monolayer molybdenum disulfide (MoS2) for luminescent quench sensing of dopamine with high accuracy and selectivity. We develop a hole-array perforated 2D MoS2 embedded with plasmonic silver dimers to harmonize the surface plasmon resonance with the PL wavelength of monolayer MoS2, which enhance it by 56-fold. We implemented the optimized perforated MoS2/dimers platform as a catalytic assay for on-chip PL quenching detection of dopamine, achieving a low limit of detection of 9.3 nM. This approach opens avenues of high-performance molecular sensing applications by improving the PL emission of 2D materials.
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ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2023
·
IF 6.8
Caixia Jin,Jingxin Cao,Kai Zhang,Xingli Zhang,Zhiguo Cao,Wei Zou
The rapid development of nanotechnology has aroused considerable attentions toward understanding the effects of engineered nanomaterials (ENMs) on the propagation of antibiotic resistance. Molybdenum disulfide (MoS 2 ) is an extensively used ENM and poses potential risks associated with environmental exposure; nevertheless, the role of MoS 2 toward antibiotic resistance genes (ARGs) transfer remains largely unknown. Herein, it was discovered that MoS 2 nanosheets accelerated the horizontal transfer of RP4 plasmid across Escherichia coli in a dose-dependent manner (0.5–10 mg/L), with the maximum transfer frequency 2.07-fold higher than that of the control. Integration of physiological, transcriptomics, and metabolomics analyses demonstrated that SOS response in bacteria was activated by MoS 2 due to the elevation of oxidative damage, accompanied by cell membrane permeabilization. MoS 2 promoted bacterial adhesion and intercellular contact via stimulating the secretion of extracellular polysaccharides. The ATP levels were maximally increased by 305.7 % upon exposure to MoS 2 , and the expression of plasmid transfer genes was up-regulated, contributing to the accelerated plasmid conjugation and increased ARG abundance in soil. Our findings highlight the roles of emerging ENMs (e.g., MoS 2 ) in ARGs dissemination, which is significant for the safe applications and risk management of ENMs under the development scenarios of nanotechnology.
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JOURNAL OF MATERIALS SCIENCE
·
2020
·Vol. 55
·期 15
·6637-6647
·
IF 3.553
Lin Qing,Dong Xiaoli,Wang Yu,Zheng Nan,Zhao Yilin,Xu Wenwen,Ding Tao
Layered transition metal dichalcogenides especially MoS 2 is favorable to be the low-cost alternative to Pt-based electrocatalysts for water splitting. Defect-rich MoS 2 nanosheets exhibiting enlarged interlayer spacing of 9.2 Å were synthesized via a solvothermal method, in which trithiocyanuric acid (TTCA) was used as a sulfur source. In addition, we synthesized MoS 2 with L -cysteine for comparison. To improve the conductivity and quantity of active exposed sites of MoS 2 nanosheets, the rGO nanosheets were introduced to hybridize with MoS 2 . With the addition of rGO, the MoS 2 /rGO hybrids exhibit different morphologies and larger interlayer spacing of 9.5 Å. Furthermore, the enhanced performance for hydrogen evolution reaction is attributed to the synergistic effect between the MoS 2 nanosheets and rGO substrates. MoS 2 /rGO-2 possesses an onset overpotential of 118 mV, a small Tafel slope of 51 mV/dec, high double-layer capacitance ( C dl ) of 15.27 mF/cm 2 , and superior cycling stability over 1000 cycles in acidic conditions.
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NANO
·
2022
·
IF 1.438
Lei Zheng,Di Xu,Dongdong Zhang
In this paper, a simple method has been used to synthesize silver-molybdenum disulfide nanoparticles (Ag-MoS 2 NPs) with photothermal and physical inhibition of bacteria. The MoS 2 nanocarriers were obtained by an environment-friendly liquid-phase separation method. The coated Ag NPs with high antibacterial activity and fluorescence property endowed the synthesized Ag-MoS 2 NPs with the ability to be traced. The Ag-MoS 2 NPs had photothermal properties with a maximum photothermal increase of 7 2 ∘ C. The results of the dual photothermal–chemical antibacterial activity using Ag-MoS 2 NP carriers showed that Ag-MoS 2 NPs had broad-spectrum inhibition activity with MIC values up to 5 . 2 ± 0 . 3 μ g/mL against Escherichia coli . The Ag-MoS 2 NPs were also used to destroy cell integrity by disrupting cell membranes and cell walls to achieve the inhibition of cell survival. The toxicity test in mice demonstrated the nontoxicity of Ag-MoS 2 NPs. Ag-MoS 2 NPs were studied for dual photothermal–chemical antibacterial activity, and the material reduced the amount of Ag NPs used, resulting in lower biotoxicity, hence providing a possible avenue for the clinical application of Ag NPs.
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ACS Applied Energy Materials
·
2022
·
IF 6.959
Jianjun Ding,Lili Song,Xiangyang Li,Lin Chen,Xiaoxiao Li,Jun Sun,Xian Zhang,Yuqiao Wang,Xingyou Tian
Construction of effective charge separation and transfer channels is a critical issue in photocatalytic energy conversion. In this work, ultrasmall fine Pt nanoparticles and MoS2 nanosheets were deposited on the surface of g-C3N4 as cocatalysts. The presence of MoS2 can effectively induce the structural reconstruction of g-C3N4 and the redistribution of surface charges. The enriched electrons localized in the S and N atoms were conductive to the reduction of Pt4+ and the promotion of the metal–support interaction, thus boosting charge separation and transfer. As a result, the obtained Pt/MoS2/g-C3N4 composite provided a highly photocatalytic hydrogen activity, up to 1595.3 μmol h–1 with an AQE of 30.9% at 435 nm, 87.6 times higher than g-C3N4. This work may provide some insights into the rational design of high-efficient composite photocatalysts for solar energy conversion.
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