JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2023
·
IF 9.9
Li Wang,Ya Jiao,Kaixin Zhao,Guohao Cheng,Lin Liu,Yongli Liu,Guifen Zhu
Molecularly imprinted polymers (MIPs) synthesized from chain functional monomers are restricted by spatial extension and exhibit relatively poor affinity and selectivity; this results in unsatisfactory applications in complex media. In this study, we prepared unique spherical carbonized polymer dots (CPDs-OH) via the incomplete carbonization of 1-allyl-3-vinylimidazolium bromide and ethylene glycol, and used it as a functional monomer to prepare a newly imprinted polymer (CPDs-OH@MIP) in aqueous media. As a result, the CPDs-OH@MIP exhibited effective recognition of oxytetracycline with an impressive imprinting factor of 6.17, surpassing MIPs prepared with chain functional monomers (1–3). Furthermore, CPDs-OH@MIP exhibited excellent adsorption for oxytetracycline (278.52 mg g −1 ) and achieved equilibrium in 30 min, with stronger resistance to coexisting cations, anions, and humic acid. Compared to other MIPs and adsorbents, the recognition performance of CPDs-OH@MIP improved 2–4 times; this polymer could remove >92.1% of oxytetracycline in real water samples with at least 10 cycle times. CPDs-OH@MIP prepared using the special spherical monomer forms a denser structure with fewer nonimprinted regions and precisely imprinted sites, remarkably improving the affinity and selectivity of MIPs combined via hydrogen bonds and electrostatic and π-π interactions. Our proposed strategy provides an effective basis for breakthroughs in the practical application of MIPs.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Lan Tang,Jiamei Huang,Chuanyan Zhuang,Sining Zhou,Lianpeng Sun,Hui Lu
Efficient high-strength antibiotic production wastewater treatment is a significant challenge that restricts sustainable pharmaceutical industry development. A novel ozone micronano-bubble (MNB) treatment system has been firstly developed to enhance oxytetracycline (OTC) degradation primarily by ozone and singlet oxygen. For practical applications employing pretreatment combined with biological treatment for raw OTC production wastewater, it is necessary to clarify the treatment performance (including the removal of parent OTC, toxicity, and organic fraction), and the potential impact on following bioprocesses. In this study, three pretreatment technologies (i.e., MNB ozonation, conventional ozonation, and thermal hydrolysis) were developed to treat real raw OTC production wastewater and were comprehensively compared. Conventional ozonation requires treatment time of over 14 h for complete removal of OTC and toxicity. Under the high-temperature operating condition (85°C), thermal hydrolysis achieves the shortest treatment time (3 h) for complete OTC removal from production wastewater without toxic substance generation. Nevertheless, the hydrolysis products and high-concentration dissolved organic matter (DOM) cannot undergo further transformation. Despite the formation of some toxic oxygen-rich transformation products, these products can be rapidly degraded to innoxious substances with lower molecular weights within 8 h via MNB ozonation. In addition, MNB ozonation can promote a 30.0% organic fraction transformation to produce more methane (584.0 mL) during the anaerobic inhibition tests than thermal hydrolysis (356.0 mL). Consequently, MNB ozonation technology is more conducive to combination with biological post-treatment. This study demonstrates the promising application potential of MNB ozonation as an efficient pretreatment technology for OTC production wastewater, and provides comprehensive insight into different pretreatment technologies to obtain an optimal treatment strategy for practical applications.
✓ 已验证
DOI
高影响因子
FISH & SHELLFISH IMMUNOLOGY
·
2023
·
IF 4.7
Ju Wang,Lei Wang,Qi Wang,Changhong Liu,Lei Zheng
Zebrafish possesses robust caudal fin regeneration which depends on multiple factors to maintain body integrity. However, it is uncertain whether the caudal fin regeneration is related to gut microbiota . Here, we investigated the effect of Lacticaseibacillus rhamnosus GG (LGG) on the regeneration of caudal fin under oxytetracycline (OTC) exposure. The results demonstrated that 1000 μg/L OTC exposure for 4 days decreased reactive oxygen species (ROS) production at 1 and 3 h post amputation (hpa), increased neutrophil recruitment at 6 hpa, enhanced the number of apoptotic cells at 1, 3, 6 and 12 hpa and inhibited Wnt signaling pathway at 48 hpa in wound site. Furthermore, OTC exposure caused dysbacteriosis by elevating level of Proteobacteria and decreasing the abundance of Firmicutes , particularly Lacticaseibacillus , thereby negatively impacting wound healing and repair. Additionally, the administration of 10 6 CFU/mL of LGG for 48 h could improve intestinal environment through increasing the colonization rate of LGG in OTC-treated larvae intestines. The regenerative process restored by LGG was accompanied with increased ROS production at 1, 3 and 6 hpa, inhibited neutrophil recruitment at 6 hpa, decreased the number of apoptotic cells at 1 hpa, and activated Wnt signaling pathway at 48 hpa in OTC-treated fish. LGG is a promising bacterium for restoring fin regeneration and provides new insights regarding the correlation among the gut microbiota and fin regeneration.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMOSPHERE
·
2023
·
IF 8.8
Yang Wu,Jia-wen Bai,Jing-ying Zhu,Zhi-hao Li,Yi-fan Shao,Qing-qing Xiao
It has been previously reported that pre-magnetization could enhance the efficacy of zero-valent iron (ZVI) in removing contaminants. However, little is known about the effects and persistence of different magnetization methods on pre-magnetized ZVI (Pre-ZVI) when used in advanced oxidation processes (AOPs). Gaining a comprehensive understanding of the durability of various pre-magnetization methods in enhancing the removal efficiency of different pollutants will significantly impact the widespread utilization of Pre-ZVI in practical engineering. Herein, we investigated the efficiency of dry and wet Pre-ZVI-activated peroxymonosulfate (PMS) in eliminating oxytetracycline (OTC) and evaluated the durability of Pre-ZVI. Additionally, we examined several factors that influence the degradation process's efficiency. Our results found that the reaction constant k values corresponding to the dry Pre-ZVI/PMS system at the pH values of 3, 7, and 9 varied from approximately 0.0384, 0.0331, and 0.0349 (day 1) to roughly 0.0297, 0.0278, and 0.0314 (day 30), respectively. Meanwhile, the wet Pre-ZVI/PMS system exhibited k values ranging from approximately 0.0392, 0.0349, and 0.0374 (day 1) to roughly 0.0380, 0.0291, and 0.0322 (day 30), respectively. Moreover, we proposed four OTC degradation pathways using LC-MS/MS and density functional theory calculations. The toxicity of the degradation products was assessed using the ecological structure activity relationship and the toxicity estimation software tool . Overall, this study provides insights into the application of Pre-ZVI/PMS that can be selectively used to eliminate tetracycline antibiotics from water.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Physical Chemistry C
·
2023
·
IF 3.7
Huan-Yu Chen,Xing-Biao Liu,Qi-Xin Guan,Can-Jun Zou,Ping-Ping Fang
The detection of antibiotics has attracted great attention among scientists and health researchers in the past decades. However, it is still difficult to realize the sensitive and selective detection of antibiotics with similar structures. Herein, the antibiotic molecules of oxytetracycline (OTC) can be sensitively and selectively detected by surface-enhanced Raman spectroscopy (SERS) on NH2–UiO-66(Zr)@Au nanoparticles (NPs). The SERS substrate of NH2–UiO-66(Zr)@Au NPs realizes a detection sensitivity of 1 × 10–12 g·L–1 for 4-mercaptobenzoic acid, indicating its high SERS activity. A high detection sensitivity of 10–11 g·L–1 is obtained for OTC on such a SERS substrate. Besides the high sensitivity, NH2–UiO-66(Zr)@Au NPs can also selectively detect OTC from streptomycin sulfate, salicylic acid, and ofloxacin by SERS on NH2–UiO-66(Zr)@Au NPs, with a selective detection limit of 10–10 g·L–1. Furthermore, OTC can be selectively detected in a real sample of river water with a detection limit of 1.0 × 10–10 g·L–1. Therefore, this study provides an effective way to enrich and detect antibiotics in real samples in the environment.
✓ 已验证
产品关联
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2020
·
IF 10.257
Xinyu Bai,Yao Zhang,Wenkai Gao,Danyang Zhao,Dapeng Yang,Nengqin Jia
A novel hollow ZnS–CdS nanocage-based molecularly imprinted photoelectrochemical (ZnS–CdS/rMIP PEC) sensor was designed for sensitive detection of oxytetracycline (OTC). O-phenylenediamine was electropolymerized onto hollow ZnS–CdS nanocages to form a polymer film, and then OTC molecules were imprinted on the polymer film through hydrogen bonding . When OTC was eluted, many specific recognition sites were formed on the polymer membrane for detecting OTC in samples. It is worth noting that the rhombohedral dodecahedral structure of hollow ZnS–CdS nanocage can provide large specific surface area, allowing more OTC molecules to be imprinted into the polymer film. Moreover, the unique hollow structure and the heterojunction formed by ZnS and CdS can significantly enhance the photocurrent response. Furthermore, molecular imprint polymer (MIP) technology greatly improves the selectivity and sensitivity of the constructed PEC sensor for detection of OTC. Under optimal conditions, the ZnS–CdS/rMIP PEC sensor has prominent linear relationship in the range of OTC concentration from 1 nmol L −1 to 3 μmol L −1 , and the detection limit is 0.10 nmol L −1 (S/N = 3). It is gratifying that the fabricated ZnS–CdS/rMIP PEC sensor displays excellent selectivity for OTC detection when interferences with similar structure exist. It also exhibits superior reproducibility and stability as well as high recovery in the investigation of actual water samples. The combination of PEC and MIP technology will provide significant reference value for effective and rapid detection of other pollutants in the environment.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2021
·
IF 5.909
Yiwu Tang,Jin Kang,Min Wang,Chongyue Jin,Jiayun Liu,Mei Li,Siyan Li,Zhilin Li
In this work, FeVO 4 nanorods were successfully synthesized and employed as peroxymonosulfate (PMS) activators for oxytetracycline (OTC) degradation. The obtained FeVO 4 nanorods exhibited excellent catalytic performance for PMS activation because of the synchronous transformations of Fe 3+ /Fe 2+ , V 5+ /V 4+ and Fe 3+ /V 4+ , and abundant adsorbed oxygen (O ads ). Almost 100% of OTC can be decomposed via FeVO 4 activating PMS in 40 min and the reaction rate constant (k) was 0.1073 min −1 , being 5.65 times of commercial Co 3 O 4 (0.0219 min −1 ). Meanwhile, FeVO 4 exhibited a good stability and reusability. In addition, the impacts of experimental parameters (catalysts and PMS dosage, temperature, pH, and co-existing anions) on OTC degradation were detected in detail. It was proved that •O 2 − , •OH and 1 O 2 were generated and the contribution role in OTC degradation followed the sequence” •OH > 1 O 2 ≈ •O 2 − . The possible mechanism of PMS activation by FeVO 4 was deeply explored and the OTC degradation pathway was deduced according to the detected degradation intermediates. This study develops one new environmental-friendly, low cost, high efficiency and stable PMS activator for the efficient removal of antibiotics.
✓ 已验证
产品关联
DOI
高影响因子
ENVIRONMENTAL POLLUTION
·
2019
·
IF 5.714
Wenqi Jiang,Jing Gao,Zheng Cheng,Wangjing Zhai,Donghui Liu,Zhiqiang Zhou,Peng Wang
Pesticide residues most likely coexist with antibiotics due to the application of animal-based fertilizers in agriculture. In this study, the degradation and enantioselectivity of beta-cypermethrin in soil and chicken manure-amended soil were investigated. The effects of oxytetracycline on the soil microbial community were also estimated. The results showed that the half-life of beta-cypermethrin in the soil was 16.9 days and that the (+)-enantiomer was degraded preferentially in both pairs of enantiomers. The metabolites cis/trans-DCCA(3-(2′,2′-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid) and 3-PBA (3-Phenoxybenzoic acid) were detected. The trans-DCCA concentrations ranged from 0.094 to 0.120 mg/kg, which were higher than the concentrations of cis-DCCA (0.091–0.120 mg/kg) and 3-PBA (0.022–0.061 mg/kg). In the presence of oxytetracycline, beta-cypermethrin degradation was inhibited slightly, while the enantioselectivity was not affected. Oxytetracycline increased the enrichment and persistence of the metabolites. Addition of chicken manure decreased the cis-DCCA residue levels in the soil and alleviated the effect of oxytetracycline; however, chicken manure increased the accumulation and persistence of 3-PBA. In addition, oxytetracycline perturbed the structure of the soil microbial community. The abundance of Proteobacteria increased, while the abundances of Firmicutes and Actinobacteria decreased. These changes might affect the biodegradation of beta-cypermethrin and its metabolites. Combined pollution with antibiotics should be considered for its potential impact on pesticide residues.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2019
·
IF 3.218
Jiaxin Lv,Xinli Chen,Susu Chen,He Li,Hong Deng
In this paper, an ultrasensitive photoelectrochemical sensor was developed for the detection of oxytetracycline , which was based on BaTiO 3 sensitized Cu 3 Mo 2 O 9 nano-composites with excellent visible-light photoelectrochemical activity. Cu 3 Mo 2 O 9 nanocrystals (NCs) with popsicle-like morphologies were synthesized through hydrothermal method and showed a very high photoelectrochemical signal. To achieve larger photocurrent density, nanostructured BaTiO 3 was then deposited on the surface of Cu 3 Mo 2 O 9 photocathodes, which led to 3-fold enhancement of the photocurrent as compared to pristine Cu 3 Mo 2 O 9 NCs. In order to obtain the specific response to oxytetracycline, oxytetracycline aptamer was fixed on the Au/BaTiO 3 /Cu 3 Mo 2 O 9 /FTO. Under visible light irradiation , the obtained aptamer/Au/BaTiO 3 /Cu 3 Mo 2 O 9 /FTO exhibited high sensitivity, good selectivity , outstanding reproducibility and low cost for detecting oxytetracycline. Furthermore, there was a linear relationship between detected signal and the oxytetracycline in the concentration range from 5 × 10 −10 to 10 −7 M, with a detection limit (3 S/N) of 4.6 × 10 −11 M under the optimal conditions. It is expected that this new photoelectric active material may have potential applications in biosensors, photocatalysis and other related fields.
✓ 已验证
产品关联
DOI
高影响因子
Materials
·
2018
·Vol. 11
·期 6
·962
·
IF 2.467
Mohammed Awad Abedalwafa,Yan Li,De Li,Xiaojun Lv,Lu Wang
Driven by economic interests, the abuse of antibiotics has become a significant concern for humans worldwide. As one of the most commonly used antibiotics, oxytetracycline (OTC) residue in animal-derived foods occurs occasionally, which has caused danger to humanity. However, there is still no simple and efficient solution to detect OTC residue. Here, an easily-operated colorimetric strategy for OTC detection was developed based on nickel ions (Ni2+) immobilized carboxymethylcellulose/polyacrylonitrile nanofibrous membranes (Ni@CMC/PAN NFMs). Owing to numerous O- and N-containing groups OTC has a strong tendency to complex with Ni2+on the strips, inducing a color change from light green to yellow visible to the naked eye. The NFMs structural features, CMC functionalization process, and Ni2+immobilization amount was carefully regulated to assure OTC detection whilst maintaining the inherent characteristics of NFMs. With the benefits of the large specific surface area (SSA) and small pore size of NFMs, the strips not only exhibited a rapid response (2 min), and low detection limit (5 nM) but also performed with good reversibility and selectivity concerning OTC detection over other antibiotics. The successful development of such enchanting nanofibrous materials may provide a new comprehension into the design and improvement of colorimetric strips.Keywords:nanofibrous membranes;nickel ions;colorimetric strips;oxytetracycline detection
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of the Taiwan Institute of Chemical Engineers
·
2016
·
IF 2.848
Yuanfeng Qi,Bibo Dai,Shengbing He,Suqing Wu,Jungchen Huang,Fei Xi,Yucheng Ma,Meng Meng
In order to solve disposal problems of hazardous solid wastes, oxytetracycline mycelia residue (OMR) and dredged heavy metal-contaminated sediments (DS) from Tai Lake were utilized as raw materials to produce ultra-lightweight ceramsite (ULC). Effects of mass ratios of organic matters/SiO 2 +Al 2 O 3 (O/SA) and MgO+Fe 2 O 3 +CaO/SiO 2 +Al 2 O 3 (MFC/SA) on characteristics of the ceramsite were investigated to optimize the ULC production process. Our results show that OMR and DS were suitable materials for ULC production, while the optimal mass ratios of O/SA and MFC/SA were 0.180–0.296 and 0.115–0.185, respectively. The addition of MFC lowered down the softening temperature and the viscosity of glass phase in ceramsite, promoting the crystallization in the glass phase. A proper MFC/SA ratio of 0.105–0.165 promoted the glass phase and increased the porosity of ceramsite. Al 2 O 3 and SiO 2 played a significant role in the formation process of crystals. However, the varying O/SA ratios only slightly impacted the variation of major crystalline phases and the viscosity of the glass phase. High MFC/SA ratios (≥0.205) decreased the crystallization of quartz, mullite and kyanite, but increased more complex crystalline phases. Additionally, the sintering process immobilized the heavy metals and could be a promising technology to control OMR pollution.
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SOIL ECOLOGY
·
2024
·
IF 4.8
Kiran Yasmin Khan,Yi Tang,Pengfei Cheng,Yunliang Song,Xinyu Li,Jiabao Lou,Babar Iqbal,Xin Zhao,Rashida Hameed,Guanlin Li,Daolin Du
Microplastics and antibiotics are emerging contaminants that can elicit considerable adverse effects on carbon and nitrogen cycles and greenhouse gas emissions. The effect of the combined occurrence of antibiotics and different types of microplastics on soil ecosystem is poorly understood. We investigated the effects of oxytetracycline (OTC), polylactic acid (PLA) microplastics, and polyethylene (PE) microplastics alone and in combination on plant root growth traits, soil extracellular enzymatic activity, and nitrous oxide (N 2 O) and carbon dioxide (CO 2 ) emissions from the soil. Plant root growth traits including root area, root surface area, root volume and root branches were negatively affected by all treatments; soil extracellular enzymatic activity was also negatively affected by all treatments expect for the cellobiohydrolase. The results showed that CO 2 emission increased in all treatments, with a maximum increase of 505 % in the PLA treatment; however, N 2 O emissions increased in the OTC treatment by 44 % but decreased in all other treatments as compared to the control. Furthermore, partial least squares path modeling analysis suggested that soil extracellular enzymes significantly influenced soil N 2 O and CO 2 emissions ( P < 0.05) and had a strong correlation with root growth traits ( P < 0.05). We thus concluded that changes in soil extracellular enzymatic activities and plant root growth traits, which were affected by different microplastic and antibiotic treatments, influenced soil CO 2 and N 2 O gas emissions.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）