ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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2020
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IF 4.872
Yilin Zhang,Dongwei Liu,Zhangsuo Liu
Background Evidence shows that individuals who are under long-term exposure to environmental PM 2.5 are at increased risk of chronic kidney disease. Various laboratory experiments also suggest several mechanistic links between PM 2.5 exposure and kidney injury. Polycyclic aromatic hydrocarbons (PAHs) are common organic chemicals existing in PM 2.5 . However, whether benzo [b]fluoranthene (BbF), the most potent carcinogens and the highest content of PAHs, plays an important role in podocyte injury via reducing autophagy, have not been reported. Methods Podocytes were exposed to different concentrations and times of BbF. Cell viability was assessed by using CCK-8. Morphological phenotypes were detected by using optical microscopy. Cytoskeletons were detected by using immunofluorescence assay. Expression of podocyte injury markers were determined by Western blot. Podocytes were observed under TEM, autophagic activity was evaluated by Western blot analysis and immunofluorescence assay. A possible effect of an inhibitor (CQ, chloroquine) or an inducer (rapamycin) of autophagy on BbF-induced podocyte injury also was examined. Results BbF changed cellular morphology, decreased cell viability and rearranged cytoskeleton. The proteins' expression level of autophagy and the numbers of autophagosomes under TEM was decreased and the proteins’ expression level of slit diaphragm was increased in a dose- and time-dependent manner. In addition, BbF-induced podocyte injury was enhanced by inhibition of autophagy and inhibited by activation of autophagy in podocytes. Conclusions Taken together, our data suggest that BbF is toxic to podocytes, as well as reduce autophagy. Furthermore, inhibition of autophagy plays a regulatory role in BbF-induced podocyte injury.
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高影响因子
Materials Today Communications
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2020
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IF 2.678
Xueyan Liu,Lingxiao Li,An Chen,Chengyou Kan,Jianhong Xu
A polymerizable rhodamine-based monomer 2-(3-(2-(3′,6′-bis(diethylamino)-3-oxospiro[isoindoline-1,9′-xanthen]-2-yl)ethyl)ureido)ethyl acrylate (RhBUEA) is first designed and synthesized, and then used in the preparation of a new water-soluble P(AM-co-RhBUEA) through precipitation polymerization of it with acrylamide (AM). Influence of the RhBUEA content on the polymerization process is investigated, and the chemical structure and composition of the copolymers are confirmed by FTIR and UV–vis spectral analysis. According to the off-on switch between spirolactam and ring-opened form of rhodamine derivative, P(AM- co -RhBUEA) prepared with 15 wt.% RhBUEA exhibits a highly sensitive and selective recognition towards Fe 3+ in aqueous solution with 0.073 μM of detection limit, accompanied with a remarkable spectral and color change. Furthermore, the spectral response is reversible by the alternating addition of Fe 3+ and EDTA to the copolymer, and the test strips prepared by P(AM-co-RhBUEA) can detect Fe 3+ colorimetrically and portably, which makes the water-soluble polymer a promising Fe 3+ sensor in the field of on-site detection.
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高影响因子
CERAMICS INTERNATIONAL
·
2020
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IF 3.83
Junxiao Tang,Wei Ji,Jingjing Xie,Yunwei Shi,Yuexu Zhu,Qianglong He,Weimin Wang
In this study, B 6.5 C-TiB 2 -SiC-BN composite was fabricated via reactive hot pressing from a powder mixture of TiCN, B, and Si. The reaction process of the powder mixture was investigated by heat treatment at elevated temperatures. The as-reacted powder products possessed a core-shell structure of TiB 2 surrounded by h-BN. During densification, the h-BN in this structure acts as a diffusion channel and lubricant, which promoted the densification process. The extremely small size, fresh surface of in-situ formed phases, and uniform dispersion in synthesized powders also contributed to sintering. The designed reactive hot-pressing sintering effectively resolves the difficulty of obtaining uniformly-dispersed BN. The obtained bulk B 6.5 C-TiB 2 -SiC-BN composite ceramic shows high relative density (98.8%) and good comprehensive mechanical properties including hardness, bending strength , and fracture toughness of 19.6 GPa, 801 MPa, and 5.31 MPa m 1/2 , respectively.
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EUROPEAN JOURNAL OF PHARMACOLOGY
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2021
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IF 4.432
Dong Wang,Xiaona Lu,Enbo Wang,Liangang Shi,Chi Ma,Xiaodong Tan
The cellular and tissue damage induced by oxidative stress (OS) contribute to a variety of human diseases, which include gastrointestinal diseases. Salvianolic acid B (Sal B), which is a natural polyphenolic acid in Salvia miltiorrhiza , exhibits prominent antioxidant properties. However, its precise function and molecular mechanisms in protecting normal intestine epithelium from OS-induced damage are still poorly defined. In this study, we tried to clarify this relationship. Here, we found Sal B addiction in the rat intestinal epithelial cell, IEC-6, prevented H 2 O 2 -induced cell viability decrease and apoptosis induction, ameliorated H 2 O 2 -induced intestinal epithelial barrier dysfunction and mitochondrial dysfunction, and suppressed H 2 O 2 -induced production of ROS to varying degrees, ranging from 10% to 30%. Moreover, by employing an ischemia reperfusion model of rats, we also discovered that Sal B treatment reversed ischemia and a reperfusion-caused decrease in villus height and crypt depth, decreased proliferation of enterocytes, and increased the apoptotic index in the jejunum and ileum. Mechanistically, Sal B treatment up-regulated the phosphorylated level of Akt and GSK3β in enterocytes in vitro and in vivo , and PI3K inhibitor LY294002 treatment abrogated the protective effects of Sal B. Meanwhile, the inactivation of GSK3β reversed the oxidative stress-induced apoptosis and mitochondrial dysfunction in IEC-6 cells. Together, our results demonstrated that the damage of intestinal epithelial cells in in vitro and in vivo models were both attenuated by Sal B treatment, and such antioxidant activity might very possibly be attributed to the activation of Akt/GSK3β signaling.
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RESEARCH ON CHEMICAL INTERMEDIATES
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2021
·Vol. 47
·期 10
·4173-4192
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IF 2.914
Fu Fengping,He Qian,Zhao Shizheng,Zhu Ting,Liao Fang
The design and fabricate new metal-free photocatalysts is one of the topics in current chemistry. In this paper, we demonstrate the ultrahigh photocatalytic performance of visible light-driven metal-free photocatalyst for selective catalytic reduction of nitro-compounds. The synthesis of 1.5–4.5-nm m-phenylenediamine-Rhodamine B copolymer dots (PmRDs) via simple hydrothermal reaction of Rhodamine B and m-phenylenediamine mixed solution. The obtained PmRDs can be used as visible light-driven metal-free photocatalyst with ultrahigh photocatalytic performance for elective catalytic reduction of nitro-compounds. Due to the hydrogen-bond and specific C–N–N bonding model between the m-phenylenediamine-Rhodamine B copolymer dots (PmRDs) and nitro-compounds, the PmRDs show high photocatalytic activity and selectivity for catalytic reduction of nitro-compounds. Under the irradiation of xenon lamp, 40 ml of 1 mM 4-nitrophenol (4-PN) could be catalyzed by 12 mg catalyst within 5 min, by calculating the rate constants up to 0.766 min −1 (25 °C). In the same way, the PmRDs are also excellent photocatalytic activity and selectivity for different nitro-compounds. Meanwhile, the efficient fast photoinduced electron transfer between the m-phenylenediamine and the Rhodamine B progress significantly improved the photocatalytic performance of PmRDs which is much higher than metal-based (such as: Ag, Ni and Cu) or metallic composite photocatalysts.
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高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
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2021
·Vol. 25
·期 8
·2443-2454
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IF 2.647
Liu Xiaopeng,Liu Yan,Wang Yun,Yuan Dingzhong,Wang Changfu,Liu Jinbiao
In this paper, polyphosphazene was synthesized as precursors using benzene-1,4-diboronic acid and hexachlorocyclotriphosphazene (HCCP) by a simple one-step ultrasonic method. Furthermore, B, N, and P co-doped carbon materials containing phosphate functional groups (denoted as BNPCs-PO 4 ) was obtained by the carbonization and functionalization of precursors at high temperature. Through the structural characterization and the investigation of electrochemical and electrosorption properties, it can be proved that BNPCs-PO 4 has excellent porous structure and electrosorption properties with the maximum electrosorption capacity of 750 ± 40 mg/g for U(VI) and the equilibrium time of 24 min. The optimal pH and applied potential for electrosorption were 5.0 and 0.9 V, respectively. Meanwhile, it also showed high selectivity under the coexistence of multiple metal ions and excellent recyclability after six cycles. The results showed the introduction of heteroatoms improved the electrosorption properties of carbon materials and BNPCs-PO 4 can be utilized as electrode for the removal of U(VI) in aqueous solution.
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高影响因子
DALTON TRANSACTIONS
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2021
·Vol. 50
·期 42
·15057-15061
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IF 4.39
Ming-Yang Cao,Chun-Li Hu,Fang Kong,Zhe-Yao Xiong,Jiang-Gao Mao
Exploration of new types of borates is important because of their promising applications in diverse fields. Two new boroselenites, namely, M(B(SeO3)3)H2O (M = Al, Ga), which represent the first IIIA metal boroselenite, were synthesized by hydrothermal reactions. M(B(SeO3)3)H2O (M = Al, Ga) possesses a unique sandwich like double-layer structure formed by two 2D [MSe2O8]5− layers interconnected by 1D [BSeO5]3− chains. More interestingly, both compounds display large band gaps (4.86/4.79 eV) and moderate birefringences (Δn = 0.063/0.064 at 1064 nm) based on density functional theory (DFT) calculations.
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高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
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2019
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IF 4.175
Yang Zhao,Hui-Long Wang,Hui-Ping Qi,De-Ying Zhao,Xin-Kui Wang
Based on the superior photocatalytic activity of low crystalline BiOCl (LCB) and temperature responsive character of poly( N -isopropylacrylamide) (PNIPAM), the novel BiOCl/GO@PNIPAM photocatalyst (PGOB) was successfully synthesized in this work by employing LCB as a photocatalytic core material, graphene oxide (GO) as a carrier for LCB, and PNIPAM as a thermo-sensitive shell material of the photocatalyst. Compared with the high crystalline BiOCl nanoplates (NPB), the core material LCB in PGOB exhibited superior photocatalytic activity and could be prepared simply by a mannitol complexation-assisted method under ambient conditions without any post-treatment. The interactions between mannitol and bismuth caused changes in chemical environment of bismuth in LCB. The morphology, crystallization, structure features and chemical compositions of the as-prepared samples were investigated by various techniques. The results showed that the prepared PGOB sample exhibited good temperature-responsive performance, excellent adsorption capacity and superior photocatalytic activities, the higher activity of which could be attributed to the effective separation and longer survival of the photogenerated carriers.
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高影响因子
ACS Sustainable Chemistry & Engineering
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2019
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IF 6.97
Shuting Qiu,Zehong Chen,Hao Zhuo,Yijie Hu,Qingzhong Liu,Xinwen Peng,Linxin Zhong
B, N co-doped porous carbon is fabricated by using chitosan as a carbon precursor, boric acid as a boron source and porogen, and ferric chloride as a multifunctional reagent (i.e., solvent, template, and activator). This strategy results in large amounts of micropores and especially mesopores that are beneficial for electrolyte ions diffusion. The as-synthesized carbon has abundant micropores and mesopores, desirable pore distribution, partial graphite structure, and dual heteroatoms doping, and thus outstanding supercapacitance performances. In a three-electrode system, the B, N co-doped porous carbon shows a high specific capacitance of 393 F g–1 at 0.5 A g–1. In a two-electrode system, the porous carbon exhibits a high capacitance of 205 F g–1 at 1.0 A g–1, and its energy density is high up to 19.1 Wh kg–1 at a power density of 400 W kg–1. Furthermore, the porous carbon exhibits excellent supercapacitance in ionic liquid electrolyte. In addition, the porous carbon possesses excellent cycling stability.
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APPLIED SURFACE SCIENCE
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2019
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IF 5.155
Yong Zhang,Keding Li,Jun Liao
The multifunctional reduced-graphene-oxide/rare-earth-metal-oxide (RGO/REMO) aerogels with three-dimensional (3D) interconnected networks were fabricated through a facile one-step hydrothermal method and freeze-drying process. It was proved that REMO nanoparticles could be easily deposited on graphene sheets in gentle conditions. To further investigate the effect of REMO on the adsorption of dyes, RGO/Nd 2 O 3 , RGO/Pr 2 O 3 and RGO/Ce 2 O 3 aerogels were used to adsorb the Rhodamine-B (RhB). The RGO/REMO aerogels all exhibited high adsorption capacity for RhB and the maximal adsorption capacity was as high as 243.4 mg·g −1 . In particular, RGO/Ce 2 O 3 aerogel had a significant adsorption efficiency for RhB, and the adsorption capacity of RGO/Ce 2 O 3 aerogel for RhB reached 130.1 mg·g −1 only in one hour. Furthermore, as for RGO/Ce 2 O 3 aerogel, the removal-rate of RhB was still more than 92% after nine repeated regeneration. The excellent adsorption capacity and high repeated utilization rate of RGO/REMO aerogels indicated that the composite adsorbent possessed potential practical application in the treatment of wastewater containing RhB.
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JOURNAL OF AOAC INTERNATIONAL
·
2019
·Vol. 99
·期 3
·760-765
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IF 1.201
Zhang Jing,Zhang Liu,Wang Wenchang,Chen Zhidong
A sensitive and convenient electrochemical method was developed for the determination of rhodamine B by a silica-pillared zirconium phosphate/nafion composite (SPZP/NAF) modified glassy carbon electrode. The SPZP was characterized with scanning electron microscopy and X-ray diffraction. Because of the layer structure and large specific surface area of SPZP, the SPZP/NAF modified glassy carbon electrode showed high electrocatalytic activity toward the oxidation of rhodamine B. Under optimal experimental conditions, the SPZP/NAF modified electrode exhibited a wide linear response to rhodamine B ranging from 0.01 to 5.0 μM and a low detection limit down to 4.3 nM (S/N = 3). This method showed good accuracy, acceptable precision, and reproducibility. This electrode had been applied in the determination of rhodamine B in preserved fruit and chili powder samples. The proposed method provided a useful tool for the assay of rhodamine B in food samples.
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高影响因子
APPLIED SURFACE SCIENCE
·
2019
·
IF 5.155
Xianlong Zhang,Dong An,Dexin Feng,Fengbing Liang,Zhen Chen,Weimin Liu,Zhenzhen Yang,Mo Xian
Herein, in situ surfactant-free synthesis of ultrathin BiOCl/g-C 3 N 4 (BOC/CN) nanosheets for enhanced visible-light photodegradation of rhodamine B was described. The formation procedure, microstructural morphology, structure, optical properties , and photocatalytic activity were researched in detail. The results show that ultrathin BOC/CN heterojunctions nanosheets were successfully constructed via one-step surfactant-free solvothermal method by introducing CN into the synthesis system of BOC, and the thickness of BOC/CN nanosheets was ~3.5 nm. The ultrathin 2D/2D BOC/CN heterojunctions significantly enhanced the photodegradation of RhB dye under visible-light irradiation. The best-performing sample BOC/CN-60 had 3.9 and 12.8 times higher photocatalytic efficiency for visible-light RhB removal compared to pure BOC and CN, respectively. The large enhancement in the photodegradation activity should be attributed to the synergistic effect of BOC and CN in BOC/CN nanosheets. The synergism reflects in the widened optical window for effective light absorption , enlarged interfacial area for more efficient electron-hole separation, and a shorter diffusion distance for facilitated charge transfer. A possible visible-light RhB photodegradation mechanism was proposed, based on theoretical analysis and active species trapping experiments.
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