CHEMICAL PAPERS
·
2019
·Vol. 73
·期 7
·1753-1759
·
IF 1.246
Xu Li,Zhang Ya-Nan,Ji Xing-Hu,He Zhi-Ke
Silicon nanodots (SiNDs) as an excellent fluorescent nanomaterial have got more and more applications. In this work, the terbium-modified silicon nanodots (SiNDs-Tb) were synthesized and successfully applied to the detection of dipicolinic acid (DPA), a biomarker of anthrax spores. Here, SiNDs serve as scaffolds and a fluorescence reference ( F 445 ), coordinating with Tb 3+ ions, while terbium ions as specific recognition elements and response signals ( F 490 and F 547 ) with zero background fluorescence. The sensing process was easily operated in aqueous media and can be finished in a short time. With a concentration range of 0.2–10 μM of DPA, the fluorescence intensity ratio ( F 547 / F 445 ) correspondingly generated quantitative changes and the limit of detection was 24 nM. It is a rapid and sensitive sensing system and provides a new approach for full exploitation of SiNDs in fluorescence assay.
✓ 已验证
产品关联
DOI
高影响因子
Scientific Reports
·
2019
·Vol. 9
·期 1
·1-10
·
IF 4.011
Zhang Xingyuan,Guo Zhao,Zhang Xiao,Gong Linji,Dong Xinghua,Fu Yanyan,Wang Qing,Gu Zhanjun
Developing robust and high-efficient synthesis approaches has significant importance for the expanded applications of upconversion nanoparticles (UCNPs). Here, we report a high-throughput synthesis strategy to fabricate water-dispersible core-shell structured UCNPs. Firstly, we successfully obtain more than 10 grams core UCNPs with high quality from one-pot reaction using liquid rare-earth precursors. Afterwards, different core-shell structured UCNPs are fabricated by successive layer-by-layer strategy to get enhanced fluorescence property. Finally, the hydrophobic UCNPs are modified with poly(ethylene glycol) monooleate (PEG-OA) though a novel physical grinding method. On the basis of mass-production, we use the as-prepared PEG-UCNPs to construct an 808-nm stimuli photodynamic therapy agent, and apply them in cancer therapy and bio-imaging.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR NEUROSCIENCE
·
2019
·Vol. 68
·期 2
·181-190
·
IF 2.577
Yan Penghui,Wu Xuejian,Liu Xiaokang,Cai Yingchun,Shao Chenglong,Zhu Guangduo
Microglial activation and inflammatory response played an important role in the secondary injury of spinal cord injury (SCI). Several microRNAs were associated with this procedure, but the underlying molecular mechanism was poorly understood. Sprague-Dawley (SD) rats were divided into four groups: SCI group ( n = 7), agomiR-325-3p group ( n = 7), and their control groups. Expression of miR-325-3p and proteins in epidermal growth factor receptor (EGFR)/mitogen-activated protein kinase (MAPK) signaling pathway was evaluated in microglia from SCI rats and primary microglia/BV2 cells activated by lipopolysaccharide (LPS). Concentrations of interleukin-1β (IL-1β) and tumor necrosis factor α (TNF-α) in supernatants were measured by ELISA. Low expression of miR-325-3p and activation of EGFR/MAPK was observed in microglia of SCI and LPS-induced primary microglia. Overexpression of miR-325-3p in LPS-induced BV2 cells inhibited microglial activation and release of TNF-α and IL-1β. Luciferase reporter assay confirmed that miR-325-3p negatively regulated EGFR by targeting its 3′-untranslated regions. Additionally, agomiR-325-3p inhibited the activation of microglia and EGFR/MAPK, alleviating the inflammatory response. These results indicated that miR-325-3p attenuated secondary injury after SCI through inhibition of EGFR/MAPK signaling pathway, the microglial activation, and the release of inflammatory cytokines, suggesting that miR-325-3p may be employed as a therapeutic target for SCI.
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2019
·Vol. 54
·期 10
·7651-7664
·
IF 3.442
Tian Chenfeng,Yuan Li,Liang Guozheng,Gu Aijuan
High thermal conductivity and high flame retardancy become necessary properties of thermally resistant thermosetting resins for many cutting-edge fields. However, building a phosphorus-free sustainable strategy is still a challenge; besides, sometimes high thermal conductivity and flame retardancy could not be simultaneously achieved, while sometimes they promote to each other, and no report focuses on explicating their relationship and mechanism. Herein, new resins with high thermal conductivity and greatly improved flame retardancy are developed through building phosphorus-free cross-linked network with three-dimensional porous framework based on boron nitride (BN) skeleton (sBN) and bismaleimide resin (BD). With the same loading of BN, sBN/BD has much higher thermal conductivity than the composite based on BN powders (BN/BD). For composites with 12.53 wt% of fillers (sBN or BN powders), the thermal conductivity of 5sBN/BD reaches 1.53 Wm −1 K −1 , about 2.4 and 9.4 times of those of 5BN/BD and BD resin, respectively. The exploring relationship between flame retardancy and thermal conductivity shows that sBN/BD composites are somewhat easier to be ignited, and the flame propagation is faster, but under continuous heating, sBN/BD has much weaker burn strength and fewer smoke releasing compared with BN/BD. 5sBN/BD has about 51.9%, 47.5%, 42.5% and 54.8% lower peak heat release rate, total smoke release, specific extinction area and maximum smoke density than BD resin, respectively. The mechanism behind these interesting results is intensively discussed.
✓ 已验证
产品关联
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2019
·Vol. 26
·期 9
·8768-8778
·
IF 2.914
Sun Yufeng,Liu Zongtang,Fei Zhenghao,Li Changshun,Chun Yuan,Zhang Aimin
Fe-Ni bimetallic nanoparticles supported on CNTs (Fe-Ni/CNTs) were synthesized, characterized, and applied for removal of 2,4-dichlorophenol (2,4-DCP) in aqueous solution. The removal performance was enhanced drastically on Fe-Ni/CNTs with respect to monometallic Fe/CNTs. The synergistic effect between Fe-Ni nanoparticles and CNTs has been studied in detail. The research results indicated that the doping of Ni played an important role in promoting the catalytic degradation of 2,4-DCP. And the presence of CNTs not only could effectively reduce the aggregation of nanoparticles but also facilitate the mass transfer of 2,4-DCP and the formation of active atomic hydrogen during the catalytic process. In addition, the removal kinetics of 2,4-DCP by Fe-Ni/CNTs were in agreement with a pseudo-first-order model, and the rate constants were dependent on a number of factors including the initial concentration of 2,4-DCP, the dosage of Fe-Ni/CNTs, pH value of the solution, and doping amount of Ni. The degradation mechanism involved the adsorption by CNTs and catalytic reduction by Fe under the stimulating of Ni, and the preferred dechlorination followed the order of para-Cl > ortho-Cl. The study confirmed that Fe-Ni/CNTs had a potential to be a promising catalytic material for removal of chlorophenol and had a great prospect for practical application.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2019
·Vol. 411
·期 20
·5175-5186
·
IF 3.286
Wei Lu,Zhang Yanhui,Eziz Nurguzal,Yang Yaru,Li Guixin,Guan Ming
An ultrasensitive electrochemiluminescence (ECL) immunosensor for alpha-fetoprotein (AFP) detection based on a poly(aniline-luminol)/graphene oxide nanocomposite was developed. The nanocomposite, which was prepared using a fast and simple chemical oxidation strategy for the first time, showed excellent ECL performance. This outstanding ECL performance is due to the formation of poly(aniline-luminol) on the graphene oxide (GO) surface and the excellent electron-transfer properties of GO. Moreover, the poly(aniline-luminol)/graphene oxide nanocomposite has abundant amino groups at its surface, making it a good platform for biomacromolecule labeling. Using the nanocomposite, a novel ECL immunosensor for the determination of AFP was successfully developed. Anti-AFP was immobilized on the surface of a poly(aniline-luminol)/graphene oxide nanocomposite-modified electrode using a glutaraldehyde crosslinking method to form the ECL immunosensor. The AFP was then captured at the modified electrode surface through an antigen–antibody immunoreaction. When the AFP was captured by its antibody, the ECL intensity decreased. This ECL immunosensor for the detection of AFP exhibited a linear range of 1.7 × 10 −12 to 1.7 × 10 −8 mg mL −1 and a detection limit of 5 × 10 −13 mg mL −1 , indicating high sensitivity and linearity across a wide concentration range. Furthermore, the immunosensor was successfully applied to determine AFP in a real-world human serum sample.
A new poly(aniline-luminol)/graphene oxide nanocomposite was prepared using a fast and simple strategy for the first time, and an ultrasensitive electrochemiluminescence (ECL) immunosensor for alpha-fetoprotein (AFP) detection based on this nanocomposite was developed
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
·
2019
·Vol. 103
·期 2
·267-273
·
IF 1.65
Wang Chengcheng,Zheng Shenghui,Zou Xiaoyan,Sun Xia,Zhang Hongwu
The development of nanotechnology has drawn increased attention to the risks of nanoparticles (NPs). In this work, the near-infrared persistent luminescence imaging technique was used to track the biodistribution of NPs in vivo in zebrafish. Zebrafish were used as a vertebrate animal model to show NPs distribution and the effects of exposure. ZnGa 2 O 4 :Cr (ZGOC) was chosen as the probe in this work. In continuous exposure experiments, the results showed more particles accumulated in the intestines than in the gills in both groups. In both the gills and abdomen, the NPs contents were greater in the ZGOC–NH 2 -treated groups than in the ZGOC groups, and the NPs caused damage to the gills and intestines. Removal exposure experiments indicated that ZGOC and ZGOC–NH 2 could be excreted from the body. The metabolism, excretion of NPs, the quantification and monitoring of NPs behavior in biological systems should be examined in further studies.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2019
·Vol. 30
·期 11
·10516-10523
·
IF 2.195
Zhao Xiaoli,Qi Shuhua,Liu Jianjun,Han Xiao,Zhang Fan
Known as a new kind of two dimensional materials, Mxene has attracted much attention in applications in polymer based composites because of their unique mechanical, thermal, and electrical properties. In this work, we report on the synergistic enhancement of Ti 3 C 2 T x Mxene nanosheets coated on carbon fiber (CF/Mxene) to epoxy resin. Ti 3 C 2 T x Mxene nanosheets were synthesized by HF etching and sonicating and used as surface sizing agent to modify NH 2 -CF by electrostatic self-assembly. NH 2 -CF/Mxene reinforced epoxy resin (NH 2 -CF/Mxene/EP) composites were prepared using a solution blending method. Their structure, morphology and performance were investigated. It is observed that Mxene possesses nanosheet structure and functional groups which are responsible for improving interfacial adhesion between NH 2 -CF and EP resin. The structural characterization showed that Mxene nanosheets are successfully attached to the NH 2 -CF surfaces. Importantly, the tensile strength, flexural strength, shear strength, and impact strength of NH2-CF/Mxene/EP composites have respectively increased by 40.8, 45.9, 38.5, and 74.4% compared to those of pristine CF/EP composites, suggesting that Ti 3 C 2 T x Mxene nanosheets use is a promising approach for improving the mechanical properties of EP-based composites.
✓ 已验证
产品关联
DOI
高影响因子
COLLOID AND POLYMER SCIENCE
·
2019
·Vol. 297
·期 5
·705-717
·
IF 1.906
Yan Qing,Liu Lulu,Wang Ting,Wang Henan
An interpenetrating double network hydrogel based on cellulose backbone and poly-dopamine dendritic structure was successfully prepared with the advantages of controlled hydrophobic drug loading, pH-responsive ability, and long-term bacteriostatic property. 13 C-NMR was used to process the structural characterization and explain the mechanism of hydrogel system’s construction. Hydrophobic drug of ciprofloxacin with carbonyl group can evenly carry in the hydrogel system, and the highest loaded ratio of ciprofloxacin was reach to 80.56%. Besides, the swelling property and the controlled drug loading ability of our prepared hydrogel were carefully studied, which showed a close relation with the hydrogel design. Moreover, the in vitro drug release experiments demonstrated that the hydrogel had an obvious pH-responsive release property of ciprofloxacin, and the result of bacteriostatic experiment also showed a long-term bacteriostatic effect on Escherichia coli , which showed potential application on biological and medical fields, including wound treatment.
.
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2019
·Vol. 10
·期 1
·1-11
·
IF 11.878
Lei Danni,He Yan-Bing,Huang Huijuan,Yuan Yifei,Zhong Guiming,Zhao Qiang,Hao Xiaoge,Zhang Danfeng,Lai Chen,Zhang Siwei,Ma Jiabin,Wei Yinping,Yu Qipeng,Lv Wei,Yu Yan,Li Baohua,Yang Quan-Hong,Yang Yong,Lu Jun,Kang Feiyu
Sodium metal batteries have potentially high energy densities, but severe sodium-dendrite growth and side reactions prevent their practical applications, especially at high temperatures. Herein, we design an inorganic ionic conductor/gel polymer electrolyte composite, where uniformly cross-linked beta alumina nanowires are compactly coated by a poly(vinylidene fluoride-co-hexafluoropropylene)-based gel polymer electrolyte through their strong molecular interactions. These beta alumina nanowires combined with the gel polymer layer create dense and homogeneous solid-liquid hybrid sodium-ion transportation channels through and along the nanowires, which promote uniform sodium deposition and formation of a stable and flat solid electrolyte interface on the sodium metal anode. Side reactions between the sodium metal and liquid electrolyte, as well as sodium dendrite formation, are successfully suppressed, especially at 60 °C. The sodium vanadium phosphate/sodium full cells with composite electrolyte exhibit 95.3% and 78.8% capacity retention after 1000 cycles at 1 C at 25 °C and 60 °C, respectively.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2019
·Vol. 10
·期 1
·1-12
·
IF 11.878
Zhu Huawei,Meng Hengkai,Zhang Wei,Gao Haichun,Zhou Jie,Zhang Yanping,Li Yin
Microbial biophotovoltaics (BPV) offers a biological solution for renewable energy production by using photosynthetic microorganisms as light absorbers. Although abiotic engineering approaches, e.g., electrode modification and device optimization, can enhance the electrochemical communication between living cells and electrodes, the power densities of BPV are still low due to the weak exoelectrogenic activity of photosynthetic microorganisms. Here, we develop a BPV based on a d -lactate mediated microbial consortium consisting of photosynthetic cyanobacteria and exoelectrogenic Shewanella . By directing solar energy from photons to d -lactate, then to electricity, this BPV generates a power density of over 150 mW·m −2 in a temporal separation setup. Furthermore, a spatial-temporal separation setup with medium replenishment enables stable operation for over 40 days with an average power density of 135 mW·m −2 . These results demonstrate the electron flow constrained microbial consortium can facilitate electron export from photosynthetic cells and achieve an efficient and durable power output.
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2019
·Vol. 55
·期 4
·1727-1737
·
IF 3.442
Peng Guangchun,Qiao Qianqian,Jin Lei,Zhang Bowei,Wang Yi,Huang Kang,Yao Qiong,Zhang Dongjiu,Zhang Zhan,Fang Tao,Wu Junsheng,He Yedong
A novel CeO 2 /MgAl 2 O 4 composite coating, fabricated via a cathode plasma electrolytic deposition (CPED) technique followed by hydrothermal synthesis, was developed in this study to explore its potential application as corrosion protection for AZ31 magnesium alloys. The microstructure observed through scanning electron microscopy indicated that reducing the duty cycle of the power source within a reasonable range during the CPED process was beneficial to form a uniform and dense MgAl 2 O 4 coating, which served as an ideal adhesive matrix for a uniform CeO 2 coating as the outermost layer. The results of electrochemical impedance spectra and neutral salt spray tests showed that the decoration of the CeO 2 layer significantly improved the corrosion resistance of the CeO 2 /MgAl 2 O 4 composite coating compared to the single MgAl 2 O 4 coating and bare substrate. Cross-cut tests revealed that the adhesion of the MgAl 2 O 4 coating and the CeO 2 /MgAl 2 O 4 composite coating were both excellent due to the strong binding between the MgAl 2 O 4 coating and the substrate.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）