Molecular Catalysis
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2023
·
IF 4.6
Yuanning Yue,Ying Liao,Jiarong Lu,Yue Pan,Meiyu Zhang,Guiyue Chen,Xin Zhou,Xinyu Kuang,Hui Zhao,Xiaobo Chen,Xiang Feng,Hao Yan,Yibin Liu,Chaohe Yang
Recognizing and modifying the acid property-dependent catalytic characteristics of catalysts are of great importance for Prins condensation reaction. Herein, a series of metal-doped M-NH 4 -PW catalysts ( M =Pt, Fe, Ir, Ru) are successfully synthesized for Prins condensation reaction of formaldehyde and propylene to produce 4-methyl-1,3-dioxane. Our findings demonstrate that the catalytic performance of M-NH 4 -PW catalysts is influenced by the chemical nature of metal site properties with different electron transfer abilities. Specifically, the new Lewis acid decorated by Pt metal on 4-H site is more favorable for the selective adsorption of formaldehyde and activation of its C O bond. Additionally, the synergistic effect between Pt metal sites and nearby O in [PW 12 O 40 ] 3− promotes the formation of C C bonds between protonated formaldehyde and propylene. Consequently, the Pt-NH 4 -PW catalyst exhibits high conversion (> 80 %) and simultaneous selectivity towards 4-methyl-1,3-dioxane selectivity (65 %). This strategy may provide valuable insights for developing efficient multifunctional catalysts for Prins condensation reactions.
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BIORESOURCE TECHNOLOGY
·
2021
·
IF 9.642
Qiang Chen,Mingzhao Guo,Yuexin Bi,Ge Qu,Zhoutong Sun,Yujun Wang,Guangsheng Luo
This work aims to synthesize S -(4-chlorophenyl)-(pyridin-2-yl) methanol ( S -CPMA) in a green, economic, and efficient way. In the water–cyclohexane liquid–liquid system, recombinant Escherichia coli ( E. coli ) was used as a whole-cell catalyst and retained > 60% of its catalytic activity after five reuse cycles. In situ accumulation of the substrate/product in the organic phase effectively improves substrate tolerance and reduces product inhibition and toxicity. Meanwhile, a microreaction system consisting of membrane dispersion and three-dimensional (3D) bending-microchannel was developed to successfully generate droplet swarms with an average diameter of 30 μm. Large specific surface area provided high mass transfer efficiency between phases. While the analogous reaction in a traditional stirred tank required > 270 min to achieve a yield of > 99%, in this biphasic microreaction system, the yield reached 99.6% with a high enantiomeric excess (ee) of > 99% in only 80 min. Efficient synthesis was achieved by reducing the time by 70%.
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JOURNAL OF POROUS MATERIALS
·
2021
·Vol. 28
·期 4
·1005-1009
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IF 2.496
Zhang Jianhui,Chen Jin,Cheng Lei,Wang Yu,Fu Jing
A facile and effective synthetic route has been utilized to synthesize nanoporous carbons (NPCs)/cobalt nanoparticles (CoNPs) composites by direct carbonization of a Co-MOF. The combination of various spectroscopic tools demonstrated that the CoNPs (about 5 nm in diameter) in the resultant composites were evenly installed in the carbon matrix without any aggregations. Furthermore, the size of the CoNPs can be easily controlled by adjusting the temperature of the hydrothermal treatment. Results of UV–Visible spectrophotometer demonstrated the significant effects of the obtained structure on the reduction of the targeted pollutant 4-nitrophenol (4-NP). The high reaction activity catalysed by CoNPs with the presence of sodium borohydride is attributed to nanostructure advantage and the high surface area.
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MOLECULES
·
2021
·Vol. 26
·期 6
·1545
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IF 4.412
Xia Niu,Xiaomei Wang,Bingyu Niu,Guoqing Li,Xinyi Yang,Yucheng Wang,Guiling Li
Background: Liver fibrosis, as a common and refractory disease, is challenging to treat due to the lack of effective agents worldwide. Recently, we have developed a novel compound, N-(3,4,5-trichlorophenyl)-2(3-nitrobenzenesulfonamide) benzamide (IMB16-4), which is expected to have good potential effects against liver fibrosis. However, IMB16-4 is water-insoluble and has very low bioavailability. Methods: Mesoporous silica nanoparticles (MSNs) were selected as drug carriers for the purpose of increasing the dissolution of IMB16-4, as well as improving its oral bioavailability and inhibiting liver fibrosis. The physical states of IMB16-4 and IMB16-4-MSNs were investigated using nitrogen adsorption, thermogravimetric analysis (TGA), HPLC, UV-Vis, X-ray diffraction (XRD) and differential scanning calorimetry (DSC). Results: The results show that MSNs enhanced the dissolution rate of IMB16-4 significantly. IMB16-4-MSNs reduced cytotoxicity at high concentrations of IMB16-4 on human hepatic stellate cells LX-2 cells and improved oral bioavailability up to 530% compared with raw IMB16-4 on Sprague–Dawley (SD) rats. In addition, IMB16-4-MSNs repressed hepatic fibrogenesis by decreasing the expression of hepatic fibrogenic markers, including α-smooth muscle actin (α-SMA), transforming growth factor-beta (TGF-β1) and matrix metalloproteinase-2 (MMP2) in LX-2 cells. Conclusions: These results provided powerful information on the use of IMB16-4-MSNs for the treatment of liver fibrosis in the future.Keywords:mesoporous silica nanoparticle;liver fibrosis;oral bioavailability;TGF-β1;dissolution rate
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2021
·Vol. 32
·期 7
·9005-9017
·
IF 2.478
Mathivanan D.,Mohan A.,Yang Yaling
Nowadays, dopamine (DA) receives huge attention because it plays an importance role in chemical transmitter for peripheral and central nervous systems. 4-Nitrophenol (4-NP) is one of the common hazardous waste, because it can cause various serious diseases to humans and environment. Herein, a simple and highly efficient technique for the detection DA and 4-NP using nitrogen–ferric-doped carbon dots (N/Fe-CDs) was reported in this article. The N/Fe-CDs were prepared using microwave digestion technique with a high quantum yield of 49.52%. The N/Fe-CDs exhibited excellence selectivity toward the detection of DA and 4-NP. Based on the quenched fluorescence between N/Fe-CDs and DA and 4-NP to detect DA and 4-NP, the linear range of DA was 0.5 - 300 µM with a detection limit of 0.07 µM (S/N =3), while the linear range of 4-NP was 0.1 - 250 µM with a detection limit of 0.02μM. Additionally, the anticipated sensing technique has been successfully applied for real sample analysis such as human serum and urine samples for DA, lake water and tap water for 4-NP with satisfactory results. So, the proposed fluorescent probe is more precise detection for biological and environmental applications.
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CATALYSIS LETTERS
·
2021
·Vol. 151
·期 9
·2513-2526
·
IF 3.186
Cui Kai,Qian Wei,Shao Zhengjiang,Zhao Xiuge,Gong Honghui,Wei Xinjia,Wang Jiajia,Chen Manyu,Cao Xiaoming,Hou Zhenshan
Furfural (FFR) is one of the most important biomass-derived chemicals. Its large-scale availability calls for the exploration of new transformation methods for further valorization. Herein, we demonstrate that Ru nanoparticles (Ru NPs)-supported on a sulfonated carbon layer coated SBA-15 can be employed as an efficient bi-functional catalyst for one step conversion of FFR into 1,4-pentanediol (1,4-PeDO). The optimum bi-functional catalyst can afford the full the conversion of FFR and 86% selectivity to 1,4-PeDO. The catalysts have been characterized thoroughly by using a complementary combination of powder X-ray diffraction, N 2 adsorption–desorption, scanning/transmission electron microscopy, Fourier transform infrared spectroscopy, elemental analysis, and X-ray photoelectron spectroscopy. The characterization revealed that acidic groups (–SO 3 H) have been introduced on the surface of the carbon layer coated SBA-15 support after sulfonation with 98% H 2 SO 4 and the surface acidity can be tuned facilely by the sulfonating time. Meantime, Ru(0) sites was highly dispersed via an impregnation and sequential reduction and directly adjacent to the surface –SO 3 H group. There existed an electronic interaction between Ru(0) sites and sulfonic groups, in which the electronic transfer from sulfonic sites to Ru(0) sites occurred. Brönsted acid sites (–SO 3 H) have a significant influence on the FFR conversion and the selectivity to 1,4-PeDO. The ordered mesoporous structure, the appropriate density of acid sites and the electron-rich Ru(0) sites accounted for the the excellent performance of the catalyst for an efficient production of 1,4-PeDO from FFR. Graphic Abstract
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CHEMICAL ENGINEERING JOURNAL
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2020
·
IF 10.652
Xue-Qi Zhang,Rong-Fang Shen,Xiao-Jing Guo,Xi Yan,Yan Chen,Jiang-Tao Hu,Wan-zhong Lang
Herein, a convenient and environment-friendly grafting and reduction strategy was used to anchor bimetallic Ag-Cu nanoparticles on polypropylene (PP) fabrics. The as-prepared samples were characterized by various techniques including FE-SEM, XRD, EDX, XPS and FT-IR. The as-prepared sample exhibits excellent activity on the catalytic reduction of highly concentrated 4-NP, and the synergistic effect between Ag and Cu nanoparticles was proved. The entire catalytic reduction was generally considered to obey pseudo-order kinetics, affording high conversion even after 15 successive recycles. These results showed that the PP based composite with Ag-Cu nanoparticles effectively provided superb catalytic efficiency and stability in 4-nitrophenol reduction, and the PP based composites were suitable in practical applications for the treatment of diverse waste water.
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JOURNAL OF INORGANIC BIOCHEMISTRY
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2020
·
IF 3.212
Han-Long Cheng,Hai-Ling Guo,An-Jian Xie,Yu-Hua Shen,Man-Zhou Zhu
At present, cancer has become a major disease threatening human health worldwide. Therefore, developing targeting guided multimode synergetic therapy has become one of the hot spots in current antitumor research and is also a great challenge. Herein, a new Fe 3 O 4 /g-C 3 N 4 @PPy-DOX nanocomposite containing magnetic iron oxide (Fe 3 O 4 ) nanoparticles (NPs), lamellar structure of graphite-like carbon nitride (g-C 3 N 4 ) and polypyrrole (PPy) shell with the loaded anti-tumor drug doxorubicin hydrochloride (DOX) was designed and prepared. The monodisperse Fe 3 O 4 nanoparticles (NPs) with the diameter of 20 nm endowed the nanocomposite with the magnetic targeting ability, reducing damage to normal tissues. It is very interesting that the Fe 3 O 4 NPs also possessed photosensitizer function for photodynamic therapy (PDT). The g-C 3 N 4 sheets as the photocatalysis towards the degradation of water for generating O 2 could effectively improve the hypoxia of solid tumors and increase the efficiency of PDT. In addition, PPy has high light-to-heat conversion efficiency, so was chosen for the cancer photothermal therapy (PTT). Finally, an anticancer drug (DOX) was loaded on the nanocomposite because the presence of mesoporous structure. Thus, the prepared Fe 3 O 4 /g-C 3 N 4 @PPy-DOX nanocomposites exhibit synergetic chemotherapy/PTT/enhanced PDT antitumor effect. This study provides an inspiration for combining targeting and multimodality to improve the anticancer efficiency.
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2020
·
IF 3.807
Xinyu Liu,Hongxue Li,Huaxu Zhou,Junjie Liu,Lequn Li,Jiyang Liu,Fei Yan,Tao Luo
4-Aminophenol (4-AP) served as the drug intermediates has been widely used or found in pharmaceutical preparations. Therefore, direct and rapid determination of 4-AP content in pharmaceuticals is highly important for human health. In this work, we demonstrate a simple and fast electrochemical method for direct analysis of 4-AP in pharmaceuticals by using the indium tin oxide (ITO) electrode modified with vertically-ordered mesoporous silica-nanochannel films (VMSF). Arising from the vertically-aligned nanochannels and high porosity of VMSF, 4-AP could permeate the VMSF and transfer to the underlying electrode surface, ultimately giving rise to the electrochemical signal. By using the differential pulse voltammetry (DPV) method, the VMSF/ITO sensor was able to detect 4-AP in a wide linear range from 0.5 μM to 400 μM. The obtained limit of detection was calculated as 0.32 μM. Owing to the good anti-fouling and anti-interference ability of VMSF, direct analysis of 4-AP in pharmaceuticals was achieved, without any complex sample pretreatments.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2020
·
IF 4.65
Xiaolong Zhang,Lei Chen,Yang Liu,Yaxin Wang,Qian Duan
We report a facile one-step, co-chemical reduction controlled synthesis of Co x Pt 100-x (x = 25, 35, 50, 65, 75) alloy nanoparticles (NPs). Alloy NPs with Co to Pt atomic ratios of 25/75, 50/50 and 75/25 were found to exhibit a pure phase and superpara-magnetism with a small NP size distribution. The saturation magnetization for Co 75 Pt 25 NPs (55.17 emu/g) was highest than that for Co 25 Pt 75 NPs (47.58 emu/g) and Co 50 Pt 50 NPs (32.38 emu/g), confirmed the best magnetic response of Co 75 Pt 25 NPs. Furthermore, the average crystallite sizes for Co x Pt 100- x (x = 25, 50, 75) alloy NPs is 5.72 nm, 5.43 nm and 5.6 nm, respectively. The observation of an obviously reduced catalytic reduction time and increased rate constant confirmed that the Co x Pt 100- x (x = 25, 50, 75) alloy NPs exhibit intensive performance for the catalytic reduction of 4-nitrophenol (4-NP). Moreover, compared with Co 25 Pt 75 and Co 50 Pt 50 alloy NPs, the Co 75 Pt 25 alloy NPs exhibit short reaction times for catalytic reduction due to their stability in aqueous solution and short induction time. The recycling ability of the alloy catalysts was certified with high yields in four reaction cycles.
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JOURNAL OF CATALYSIS
·
2020
·
IF 7.888
Xiqiang Tian,Muhammad Zahid,Jiang Li,Wang Sun,Xiaoyu Niu,Yujun Zhu
The addition of a suitable co-catalyst is an encouraging way to enhance the catalytic performance of Pd based catalyst with low content. Herein, we describe an easy synthesis of Mo 2 N-TiO 2 with well-dispersed Mo 2 N nanoparticles through one pot evaporation-induced self-assembly and nitridation treatment method. Moreover, a green bio-reductive approach with Catalpa Fruit ( CF ) extract was adopted to fabricate Pd/Mo 2 N-TiO 2 catalysts for promoting selective hydrogenation of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP) as model reaction. Among these Pd/Mo 2 N-TiO 2 catalysts, 0.8 wt%Pd/Mo 2 N-TiO 2 exhibits significantly high catalytic activity for selective hydrogenation of various nitrophenols and cinnmaldehyde. Importantly, the catalytic activity of the catalyst prepared by the reduction method of the CF extract is higher than that prepared by the reduction method of NaBH 4 . A serials of characterization, including XRD, N 2 adsorption–desorption, TEM, XPS, CO chemisorption and CO-FTIR etc., was carried out to investigate the influence of the prepared method on the surface Pd species and activity. The high performance can be attributed to the specific nanostructure characteristics of the catalyst and the good synergistic effect between Pd and Mo 2 N, improving the dispersion of Pd nanoparticles atoms and the exposure of more active Pd atoms (surface Pd 0 species) on 0.8 wt%Pd/Mo 2 N-TiO 2 due to the CF extract as reductant.
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MICROCHEMICAL JOURNAL
·
2020
·
IF 3.594
Hao Guo,Tian Fan,Wenqin Yao,Wenhu Yang,Ning Wu,Hui Liu,Mingyue Wang,Wu Yang
Herein, a novel electrochemical sensor based on ZIF-67/MWCNT-COOH/Nafion composite was designed and prepared for simultaneous detection of 4-aminophenol (4-AP) and acetaminophen (AMP). The electrochemical behaviors of the 4-AP and AMP on the ZIF-67/MWCNT-COOH/Nafion electrode were explored via cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The results exhibited that the designed electrochemical sensor possessed superior electrocatalytic activity for 4-AP and AMP, which was attributed to the highly ordered porous structure of ZIF-67, the outstanding electrical conductivity and high electrocatalytic activity of MWCNT-COOH. Under optimization conditions, the DPV response of the prepared electrode depicted a wider linear response concentration range of 0.2 to 200 μM for 4-AP, and 0.1 to 100 μM for AMP, respectively. And the lower detection limits (LOD) of 0.01 and 0.07 μM were obtained for 4-AP and AMP, respectively. More importantly, the acquired electrode was applied to Yellow river water and Paracetamol tablets for analysis of 4-AP and AMP, which exhibited satisfying recovery of 98.2% ~ 106.7% for 4-AP and 94.7% ~ 99.6% for AMP, respectively. In a word, the constructed electrochemical sensing platform delivered a promising potential in real application.
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