FOOD CHEMISTRY
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2024
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IF 8.5
Xinhui Shu,Ping Guo,Gan Zhang,Wei Zhang,Hong Hu,Juan Peng,Yonghua Xiong,Bingfeng Ma,Weihua Lai
Pyrimethanil (PYR) is a fungicide that is harmful to consumers when present in foods at concentrations greater than maximum permitted residue levels. High-performance immunoprobes and dual-readout strategy may be useful for constructing sensitive lateral flow immunoassay (LFIA). Herein, the prepared litchi-like Au–Ag bimetallic nanospheres (LBNPs) exhibited high mass extinction coefficients and fluorescence quenching constants. Benefiting from LBNPs and dual-readout mode, the limits of detection of LBNPs-CM-LFIA and LBNPs-FQ-LFIA for PYR were 0.957 and 0.713 ng mL −1 , which were 2.54- and 3.41-fold lower than that of gold nanoparticles-based LFIA, respectively. The limits of quantitation of LBNPs-CM-LFIA and LBNPs-FQ-LFIA were 3.740 and 1.672 ng mL −1 , respectively. LBNPs-LFIA was applied to detect PYR in cucumber and grape samples with satisfactory recovery (90%–111%). LBNPs-LFIA showed good agreement with LC-MS/MS for the detection of PYR in the samples. Accordingly, this sensitive and accurate dual-readout LFIA based on LBNPs can be effectively applied for food safety.
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高影响因子
Foods
·
2024
·Vol. 13
·期 12
·1845
·
IF 4.7
Yiming Zhao,Baoshan He,Danyang Li,Leyan Gao,Wenjie Ren
In the realm of analysis, the lateral flow immunoassay (LFIA) is frequently utilized due to its capability to be fast and immediate. However, the biggest challenge of the LFIA is its low detection sensitivity and tolerance to matrix interference, making it impossible to enable accurate, qualitative analyses. In this study, we developed a new LFIA with higher affinity and sensitivity, based on a nanobody (G8-DIG) and CuS nanoflowers-Au (CuS NFs-Au), for the detection of aflatoxin B1(AFB1) in maize. We synthesized the immunoprobe G8-DIG@CuS NFs-Au, stimulated the in situ development of Au nanoparticles (Au NPs) on Cu NFs by electrical displacement, and obtained Cu NFs-Au for fixing the G8-DIG. G8-DIG@CuS NFs-Au probe-based LFIAs may, in ideal circumstances, use a strip chromatography reader to accomplish sensitive quantitative detection and qualitative visualization. AFB1has a detection range of 2.82–89.56 µg/L and a detection limit of 0.87 µg/L. When compared with an LFIA based on CuS NFs, this sensitivity is increased by 2.76 times. The practical application of this method in corn flour demonstrated a recovery rate of 81.7% to 117%. Therefore, CuS NFs-Au show great potential for detecting analytes.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2024
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IF 8.1
Jin Wu,Yunlong Chen,Xianzhi Hu,Futing Zi,Yue Lin,Yufang Li
Developing an efficient and cleaner technology to recover gold (III) from aqueous media is vital for both economic and environmental perspectives. Herein, Cu 2 S was first found with well Au (III) recovery ability. Rod and flower-like Cu 2 S nanoparticles prepared by dynamic modulation, with jaggy micro-surface and relatively hard-wearing shape, was found with well Au (III) affinity. Results proved that this adsorbent could work better over a relatively wide pH from 2 to 5, and temperature from 25 to 55 °C, and that attained high gold capacity of 5,582 mg/g which obviously exceeded other reported adsorbents, indicating well application potential. XRD, TEM, and XPS studies demonstrated that adsorbed Au (III) was reduced as Au (0) by Cu 2 S. DFT studies verified that Au (III) recovery is related with the formation of “Cu-S-Au” bridge-like linkage and the unceasingly produced new adsorption sites after adsorbed Au atom’s migration and agglomeration. Au (III) recovery ability and selectivity in the actual sample was proved to be well too. Also, more than 90% gold on Cu 2 S could be recovered with HNO 3 . This study is of great theoretical and practical significance for cleaner Au (III) recovery from various aqueous media.
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CHEMISTRY OF MATERIALS
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2024
·
IF 7.2
Xiao-Mei Yu,Yihu Ke,Xue Wang,Hai Liu,Hong Yuan
The specific structure of the support and the interactions between the catalyst components can lead to electron transfer, which in turn could affect the catalytic performance in heterogeneous catalytic reactions. In this paper, we have successfully prepared MnxOyCz composite materials from the calcination of the Mn-organic framework. Then bimetallic Au–Pt nanoparticles (NPs) were supported onto MnxOyCz via the colloidal-deposition method. These catalysts were tested in the selective oxidation of glycerol to glyceric acid under basic conditions. The results demonstrated that the catalytic activity of the bimetallic Au–Pt/MnxOyCz catalyst is considerably superior to those of the monometallic (Au and Pt) supported catalysts. Under the optimized conditions, 100% of glycerol can convert with 57.3% selectivity of glyceric acid. Multicharacterizations showed that the strong interaction between Au and Pt in the Au–Pt/MnxOyCz catalyst can enhance the dispersion of Au–Pt alloy NPs, promoting the electronic coupling effect on the metal surface. At the same time, the rich oxygen vacancies in this catalyst can facilitate the activation of oxygen, which causes the Au–Pt/MnxOyCz catalyst to show better catalytic activity. Specifically, the interaction between Au and Pt not only decreases the particle size of the Au–Pt alloy NPs but also promotes the reduction of Mn-based oxides and the mobility of oxygen. The absence of Au leads to a decrease in Pt 4f7/2 binding energy, resulting in an enrichment of electrons at the Pt active site and enhancing the oxidation ability of the primary hydroxyl group. In addition, the Au–Pt/MnxOyCz catalyst showed excellent stability without substantial loss of activity after being recycled five times. The insights and methodology may provide some new guidance for the reasonable design of bimetallic catalysts for the catalytic oxidation of biopolyols under mild conditions.
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JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
·
2018
·Vol. 29
·期 2
·232-239
·
IF 1.444
Zhao Yanling,Xie Xianmei
As a kind of important water pollutant, heavy metal ions have a detrimental effect on the health of human. In this study, Au@Ag core-shell nanoparticles were synthesized by simple reduction of Ag + around Au nanoparticles and functionalized by DNAzyme. Based on thymine-Hg2+-thymine binding mode, a sensitive aptamer biosensor was constructed by utilizing functionalized Au@Ag core-shell nanoparticles as labels, and the sensitivity was enhanced by DNAzyme due to the catalysis toward H2O2. Under optimal conditions, square wave voltammetry was carried out to measure the current derived from Au@Ag nanoparticles labels. The current response of biosensor increased with the increasing of Hg2+ concentration, which presented linear relation in the range of 0.002-20 μg L -1 with limit of detection of 0.006 μg L -1. Meanwhile, the electrochemical biosensor showed superior reversibility, stability, repeatability, and selectivity.
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Weiqian Cai,Youqun Wang,Linshan Xiong,Yingjie Zheng,Zhibin Zhang,Xiaohong Cao,Yunhai Liu
Cuprous oxide (Cu 2 O), a promising semiconductor material, has been less employed in the photocatalytic removal of uranium. In this work, silver and gold nanoparticles were introduced on the surface of Cu 2 O. HR-TEM, XRD and XPS were applied in characterized the physic-chemical properties of composite. In comparison to Cu 2 O, Au modified Cu 2 O (Au/Cu 2 O-N) demonstrated a significantly enhanced uranium removal rate, reaching 100% within 120 minutes. This represents a 2-fold increase in the uranium removal rate compared to pure Cu 2 O-N. The reason con be interpreted including the red-shift of the absorption band from 600nm-800nm, the formation of Schottky junction between Au and Cu 2 O, the electron traps constructed by Au itself. Consequently, the rate of photogenerated electron-hole complexation is significantly diminished. Free trapping and EPR prove that reactive radicals are O 2 - . This has led to the development of a novel approach, namely the synergistic strategy of noble metal loading and nitrogen-doped cuprous oxide, which has the potential to facilitate the visible light removal of U(VI) from toxic wastewater.
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FOOD CONTROL
·
2024
·
IF 5.6
Xinchen Wu,Limei Yin,Shipeng Gao,Ruiyun Zhou,Yang Zhang,Shanshan Xue,Heera Jayan,Hesham R. El-Seedi,Xiaobo Zou,Zhiming Guo
Patulin (PAT), a major contaminant in apples, poses a huge threat to human health as well as the economic sector. There is an urgent need to develop a sensitive, selective, and fast-responsive method to detect PAT in apples. However, one of the main challenges is overcoming the interferences of complex food matrices. In this study, we developed a highly sensitive competitive SERS sensor based on plasmonic nanoparticles modified by aptamers. The study utilized the formation of nanocomposites through aptamer-modified Au@Ag nanoparticles (NPs) and gold nano-stars (AuNSs) to induce high-intensity Raman signals from the SERS tag. Subsequently, in the presence of PAT, the nanocomposites underwent decomposition, evident through the significant decrease in SERS intensity. According to the standard curve established in this study, the detection limit was 0.0281 ng/mL. The competitive sensor was applied to spiked apple fruit and juice samples, indicating a recovery rate ranging from 91.98% to 102.94%. The excellent analytical performances and high sensitivity observed suggest the potential of the plasmonic nanocomposite sensing strategy in detecting PAT in real matrices.
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SENSORS AND ACTUATORS B-CHEMICAL
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2024
·
IF 8
Bin Zhang,Yiquan Liao,Yichang He,Minggang Zhao,Ye Ma
The self-assembly of gold nanoparticles (Au NPs) has attracted wide attention in the fields of sensing, catalysis and various optical devices. Compared with conventional self-assembly methods in the bulk solution or on the solid substrates, the liquid-liquid interface (LLI) provides a versatile plane with nanoscale flatness for addressable NP assembly. Here, we report a self-assembled Au NPs metasurface at the water-oil interface using a four-electrode electrochemical system that is stable, controllable, and enables dual-mode in-situ sensing. By building electrostatic energy well at LLI, a closely packed metasurface can be formed, which shows strong surface plasmon resonance (SPR) effect. In the presence of analytes, the metasurface generates significant changes in reflectance and surface-enhanced Raman scattering (SERS) spectra, which can be utilized as two sensing modes. Cu 2+ and Hg 2+ were targeted as two proof-of-concept analytes for the sensor. The limit of detection (LOD) can reach 0.147 nM and 0.421 nM, respectively, showing outstanding performance in heavy metal detection.
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TALANTA
·
2025
·
IF 6.1
Rongjing Hu,Shilan Fu,Yongcong Zhou,Zhenyu Lin,Fengfu Fu,Yongqiang Dong
The current surface-enhanced Raman scattering (SERS) substrates typically feature a single energy level, posing challenges in coordinating electromagnetic enhancement (EM) and chemical enhancement (CM), thereby limiting the sensitive detection of numerous crucial target molecules. In this study, novel aggregated nanorings (a-NRs) hybridizing Ag, Au and AgCl are constructed as SERS substrates. On one hand, the obtained a-NRs exhibit robust localized surface plasmon resonance absorption, whose wavelength can be tuned to match three commonly used laser wavelengths (532, 633 and 785 nm) to gain strong EM effect. On the other hand, these materials possess the Fermi levels of Au nanoparticles and Au/Ag alloy, in addition to the valence band and conduction band of AgCl. The abundant energy levels of the obtained a-NRs facilitate increased charge transfer opportunities for molecules, leading to a strong CM effect. Therefore, the obtained a-NRs show ultra-high SERS sensitivity towards numerous molecules. Moreover, the unique chemical composition makes the obtained a-NRs have good long-term stability in terms of SERS activity. Besides providing high-performance SERS substrates, the valuable experience for coordinating EM and CM to construct highly active SERS substrate demonstrated in this work are expected to significantly advance the application of SERS.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Libo Sun,Qingtai Xie,Heshun Jing,Jindong Xie,Wenyu Tan,Baorong Duan,Xun Sun,Caixia Qi,Huijuan Su
The development of nanogold catalysts with high activity and high stability is of great significance for their industrial applications. In this paper, Au-PDA@Fe 3 O 4 catalysts were prepared through the gold sol adsorption method. First, micron-sized magnetic Fe 3 O 4 spheres were synthesized via a solvothermal method, serving as the core to endow the catalyst with excellent recyclability. Subsequently, a layer of polydopamine (PDA) shell was polymerized on the magnetic core surface. By controlling the timing of introducing the gold sol containing Au nanoparticles (NPs), the spatial position of Au NPs within the PDA layer was regulated, leading to a series of magnetic core-shell nano gold catalysts with varying spatial positions of Au. Using the 4-nitrophenol (4-NP) hydrogenation as the probe, the influence of Au spatial position, Au size, and other conditions on the catalytic performance was investigated. Results showed that, in the prepared Au-PDA@Fe 3 O 4 -16 catalyst, the Au NPs are encapsulated within the PDA shell and positioned close to the outer layer. This not only provides remarkable stability to the Au NPs but also maintains their proximity to the surface of the PDA shell, allowing easier access of the substrate 4-NP to the Au NPs and conferring good reactivity upon the catalyst. The strong electron metal-support interaction between PDA and Au enables PDA to effectively stabilize Au NPs. The prepared Au-PDA@Fe 3 O 4 -16 catalyst exhibits excellent stability, maintaining a high conversion rate of 91 % even after 14 cycles of use. Our findings not only deepen the understanding of the catalytic mechanisms involved but also pave the path towards the creation of highly efficient and robust gold-based catalysts, facilitating their widespread utilization in industrial applications.
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ACS Sensors
·
2025
·
IF 9.1
Shanshan Feng,Peiyi Zhang,Hui Chen,Bo Zhou,Ying Qin,Tingting Fan,Qinsheng Sun,Yan Chen,Yuyang Jiang
Colorectal cancer (CRC) is a common malignancy requiring early screening to improve patient outcomes. Current screening methods such as colonoscopy and fecal occult blood tests have several limitations including high cost, poor specificity, invasiveness, and inconvenience. Recent research has identified specific bacterial communities associated with CRC, notably Parvimonas micra (P. micra), which serves as a biomarker for early screening and diagnosis owing to its accumulation in the malignant tissues and feces of CRC patients. Herein, we employed the whole-bacterium systematic evolution of ligands by the exponential enrichment (SELEX) method to isolate high-affinity aptamers against P. micra using 17 selection cycles. These aptamers were subsequently bound to Au@Fe3O4 nanoparticles, and the interaction of P. micra and aptamers inhibited the peroxidase-like activity of Au@Fe3O4 nanoparticles, thereby blocking the 3,3′,5,5′-tetramethylbenzidine (TMB) chromogenic reaction and resulting in a measurable reduction in absorbance. This colorimetric detection strategy demonstrated a linear response across a range of 100–108 CFU/mL for P. micra with a limit of detection of 11 CFU/mL. Using a colorimetric aptasensor, we assessed the abundance of P. micra in clinical fecal samples and found significantly higher levels in the feces of CRC patients as compared to that of healthy individuals, which was consistent with the quantitative polymerase chain reaction results. This study therefore represents the first successful identification of an aptamer with high affinity and specificity for P. micra, leading to the development of a highly specific and sensitive aptasensor for its detection. The presented approach has a significant potential for CRC screening and diagnosis.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Shuaimei Li,Wenlei Zhang,Congwei Wang,Gang Li
Ethylene glycol (EG) is extensively utilized as anti-freezer and deicer, which would bring potential health risk under unintentional exposures especially with hazardous inhalation of EG aerosols or vapors. In this study, ZnIn 2 S 4 (ZIS)/WO 3 core-shell nanofibrous heterostructure loaded with optimized Au nanoparticles (NPs) was prepared for superiorly sensitive and selective EG gas sensing. The ternary Au/ZIS/WO 3 heterostructures exhibited an excellent response ( Ra/Rg =98.92) to 50 ppm EG, demonstrating an enhancement of 3.5 times compared to the binary ZIS/WO 3 , and a substantial improvement of 59.5 and 24.1 times compared to pure WO 3 and ZIS, respectively. The ternary Au/ZIS/WO 3 heterostructures also possessed an extremely low detection limit of 6 ppb, as well as excellent selectivity , repeatability, and long-term stability. This exceptional gas sensing performance can be attributed to its distinctive ternary Au/ZIS/WO 3 heterostructures with high specific surface areas . This unique structure not only facilitate the activation of abundant active oxygen species, but also promote the spillover effect of Au and enhance effective electronic distribution, thereby providing more EG adsorption sites, which was confirmed by density functional theory calculation. The synergistic effect arising from the metal-semiconductor interface and the core-shell heterostructure presents a novel avenue for advancing high-performance sensor technologies.
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