JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2019
·
IF 6.361
Bo Yang,Peng Zhou,Xin Cheng,Haishen Li,Xiaowei Huo,Yongli Zhang
This study aimed to investigate the simultaneous removal of methylene blue (MB) and total dissolved copper (TCu) by heterogeneous zero-valent iron (ZVI) Fenton-like system (ZVI/H 2 O 2 ) and elucidate the mechanism of synergistic effect for co-contaminants removal. Hydroxyl radical ( OH) formation was hypothesized to be the dominant pathway for the oxidation of MB, confirmed by the quenching experiments and ESR analysis. And the synergistic effect of TCu and ZVI greatly promoted the release of Fe 2+ , further accelerating the generation of hydroxyl radical ( OH) via Fenton reaction. The generation process of OH was unveiled by quenching experiments and electron spin resonance (ESR) analysis, while the processes of ZVI corrosion and TCu reduction were revealed through several characterization approaches including SEM , XRD , FTIR and XPS . The degradation pathway of MB was also investigated by LC-MS analysis. The MB initial concentration, TCu initial concentration, H 2 O 2 dosage, ZVI dosage and initial solution pH could play crucial roles in the removal of MB and TCu. The influence of water matrix including inorganic anions (Cl − , NO 3 − , HCO 3 − ) and actual water was finally conducted to elucidate the role of natural organic matter (NOM) in the environmental systems.
研究领域:
环境科学
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化学工程
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DOI
PubMed
高影响因子
Molecular Catalysis
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2019
·
IF 2.938
Shuying Gao,Fu Yang,Xianfeng Liu,Xu Hu,Changjian Song,Shijian Zhou,Yan Kong
Multi-components-bearing mesoporous silica pays the way to the controlling of catalytic selective oxidation by virtue of the synergy of several functional active species in the catalyst, but still faces huge challenge in design and preparation of this functional catalyst. Herein, we rationally constructed a steady ternary-component catalyst (FAM-MS) by incorporating three kinds of catalytically active centers Fe, Al and Mn into the skeleton of mesoporous silica, which reveals a potential industrial application prospect. These resultant catalyst samples were investigated thoroughly by various means, which include XRD, HRTEM, N 2 -isotherms, UV–vis, and XPS. The present results indicated that the FAM-MS catalyst affords narrow pore size distribution (2.71 nm), 2D hexagonal mesostructure and huge specific surface area (918 m 2 ·g −1 ) which accordingly contributes to a capacious catalytic reaction space. In addition, the synergy of tri-active components shows greater ability to improve the selectivity of DHB, compared to single-active component and dual-active components ones. As a result, the catalyst FAM-MS shows an optimal catalytic activity (22.8% conversion & 93.1% selectivity DHB) under the optimal reaction conditions for selective oxidization of high concentration of phenol solution (ca. 30%) with H 2 O 2 by virtue of the solubilizing effect of lauryl sodium sulfate in the reaction system. More importantly, the resulted catalyst reveals a durable catalytic activity with puny activity-loss (20% conversion & 90% selectivity DHB) during the fifteen recycling, which exhibits potential industrial application prospect.
研究领域:
材料科学
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环境化学
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DOI
高影响因子
MICROCHEMICAL JOURNAL
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2020
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IF 3.594
Wenqian Sun,Xuan Cai,Zhenxing Wang,Hongli Zhao,Minbo Lan
In this work, a facile in-situ reduction method was developed for the modification of carbon fiber microelectrode (CFME) to build novel electrochemical sensors for the detection of H 2 O 2 . The polydopamine (PDA) was employed as the surface modification material for one-step decoration of AuAg bimetallic nanoparticles through in-situ reduction on the surface of PDA/CFME. Compared to Au-PDA/CFME and Ag-PDA/CFME, 2Au1Ag-PDA/CFME (immersed PDA/CFME in AgNO 3 for 1 h, HAuCl 4 •4H 2 O for 2 h in order) exhibited higher electrocatalytic activity toward H 2 O 2 sensing due to bimetal synergism. Under the optimal condition, the 2Au1Ag-PDA/CFME appeared a wide linear range of 0 μM - 55 μM (R 2 = 0.990), 55 μM – 2775 μM (R 2 = 0.991) with high sensitivity (12966 μA mM −1 cm −2 , 0–55 μM; 2534 μA mM −1 cm −2 , 55–2775 μM), and low detection limit (0.12 μM). Furthermore, good selectivity and repeatability of 2Au1Ag-PDA/CFME favored its applications in biological samples, especially in cellular level. The detection of H 2 O 2 released from HepG2 living cells was realized by applying 2Au1Ag-PDA/CFME, indicating a potential usage of the fabricated electrode for H 2 O 2 detection in cancer cells. In addition, the above simple in-situ reduction method based on PDA's adhesion and reducibility offered a universal strategy to decorate noble metals onto microelectrode for different application in the future.
研究领域:
分析化学
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生物医学工程
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电化学传感器
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
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2021
·Vol. 32
·期 5
·2106886
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IF 18.808
Haisheng Gong,Zengxi Wei,Zhichao Gong,Jingjing Liu,Gonglan Ye,Minmin Yan,Juncai Dong,Christopher Allen,Jianbin Liu,Kang Huang,Rui Liu,Guanchao He,Shuangliang Zhao,Huilong Fei
Electrochemical H 2 O 2 production through the 2-electron oxygen reduction reaction (ORR) is a promising alternative to the energy-intensive anthraquinone process. Herein, by simultaneously regulating the coordination number of the atomically dispersed cobalt sites and the nearby oxygen functional groups via a one-step microwave thermal shock, a highly selective and active Co N C electrocatalyst for H 2 O 2 electrosynthesis that exhibits a high H 2 O 2 selectivity (91.3%), outstanding mass activity (44.4 A g −1 at 0.65 V), and large kinetic current density (11.3 mA cm −2 at 0.65 V) in 0.1 m KOH is obtained. In strong contrast to the typical Co N 4 moieties for the 4-electron ORR, the present Co N C catalyst possesses a low-coordinated Co N 2 configuration and abundant epoxide groups, which work in synergy for promoting the 2-electron ORR, as demonstrated by a series of control experiments and theoretical simulations. This study may provide an effective avenue to modulating the composition and structure of electrocatalysts at the atomic scale, leading to the development of new electrocatalysts with unprecedented reactivity.
研究领域:
材料科学
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电化学
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催化科学
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高影响因子
CHEMOSPHERE
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2021
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IF 7.086
Xiaoping Liu,Yunbo Zhai,Guangli Liu,Xiangmin Liu,Bei Wang,Zhexian Wang,Ya Zhu,Yuwei Fan,Haoran Shi,Min Xu
Without extra adjustment of pH, the effects of cupric ions (Cu(II)) and hydrogen peroxide (H 2 O 2 ) alone or in combination on sludge dewatering were studied. It showed good dewatering capability after treated by Cu(II) and Cu(II)/H 2 O 2 , which indicated by the capillary suction times (CST) decreased from 120.8 ± 4.7 s (control) to about 40 s, and the water content (Wc) of sludge cake dropped by about 10%. The results showed that the extracellular polymeric substances (EPS) were destroyed, which characterized by a significant decrease in the biopolymers’ concentrations in tightly-bound EPS. Meanwhile, more rough and porous microstructures and higher zeta potentials were obtained after conditioned. Based on the changes of physicochemical properties of sludge, the variations of EPS, and the identification of reactive species, two distinct mechanisms of improved sludge dewatering were postulated. As for Cu(II) treatment, it was mainly due to the surface charge neutralization, strong cytotoxicity of Cu(I) produced by intracellular reduction of Cu(II), and pH decline caused by Cu(II) hydrolysis that improved sludge dewatering performance, which could be noted as a “non-radical pathway”. When in combination with H 2 O 2 , hydroxyl radicals (·OH) produced by Cu(II)-catalyzed Fenton-like process played a dominant role in degrading sludge flocs and EPS, which could be regarded as a “radical pathway”.
研究领域:
环境科学
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污水处理
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PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
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2023
·
IF 6.2
Kai Xuan,Taiguang Li,Yongmei Hao
The photo-Fenton system degrades pollutants, which can not only take the advantages of photocatalysis and Fenton reaction, but also avoid the drawbacks of each. However, removing pollutants without the addition of hydrogen peroxide (H 2 O 2 ) in photo-Fenton systems is still a challenge. Therefore, it is an outstanding strategy that inner-generate H 2 O 2 can provide more hydroxyl radicals to enhance the degradation of pollutants. This study reports a ZnIn 2 S 4 /Fe-POMs photo-Fenton system capable of degrading environmental pollutants due to the reaction between inner-generate H 2 O 2 (0.0248 mM in 15 min) and the stable circulation of Fe 3+ /Fe 2+ . As a result, the photodegradation efficiency of carbamazepine by ZnIn 2 S 4 /Fe-POMs can reach 93.92% within 60 min simulated solar irradiation even under neutral conditions. In addition, ZnIn 2 S 4 /Fe-POMs can remove Cr (VI) completely within 10 min under visible light irradiation. This work not only experimentally verifies the inner-generate H 2 O 2 can accelerate the Fe 3+ /Fe 2+ conversion, but also broadens the initial pH range (pH=3–9) for constructing efficient photo-Fenton systems.
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高影响因子
ACS Biomaterials Science & Engineering
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2026
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IF 6
Yulan Zhao,Quan Xu,Shijie Zheng,Yi Liu,Zhiyong Song,Heyou Han
Drug-resistant bacterial infections rank among the most critical public health threats across the globe. The development of novel antibiotics falls considerably behind the rise of bacterial resistance. The advancement of nanotechnology offers novel opportunities to address the challenges posed by drug-resistant bacterial infections. In recent years, copper-based nanomaterials have gained widespread application in chemodynamic therapy (CDT) due to their favorable nanoenzymatic activities. However, their therapeutic efficacy is seriously constrained by the insufficient H2O2 supply and overexpressed glutathione (GSH) within the infected wound microenvironment. Therefore, a H2O2 self-supplying and GSH-depleting nanosystem (CuO2@ZIF-8) was rationally constructed by simply encapsulating copper peroxide (CuO2) within a zeolitic imidazolate framework-8 (ZIF-8). Under the acidic microenvironment of the infection sites, ZIF-8 underwent degradation to liberate Zn2+ ions, which exhibited potent antibacterial activity. Meanwhile, after being degraded, ZIF-8 released CuO2, which in the slightly acidic infected microenvironment decomposed to generate H2O2 and Cu2+. The released Cu2+ then catalyzed the H2O2 into highly toxic hydroxyl radicals (·OH), thus achieving a great antibacterial effect between CDT and Zn2+. In addition, Cu2+ could be reduced to Cu+ by the overexpressed GSH, further enhancing the efficacy of CDT. In vitro antibacterial assay showed that due to the antibacterial effect of CDT and Zn2+, the antibacterial rate of CuO2 @ ZIF-8 reached as high as 98.8%, which was significantly superior to that of ZIF-8 or CuO2 used alone. In vivo assay showed that CuO2 @ ZIF-8 had good antibacterial effects and excellent wound healing with great in vivo biosafety. In conclusion, the CuO2 @ ZIF-8 nanoplatform developed in this work has considerable promise for future biomedical applications.
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高影响因子
Water
·
2021
·Vol. 13
·期 13
·1724
·
IF 3.103
Liping Liang,Fenfen Xi,Liubiao Cheng,Weishou Tan,Qiang Tang,Xu Meng,Zhenjiong Wang,Bo Sun,Aijie Wang,Jian Zhang
The coupling use of the heterogeneous Fenton-like process (zero-valent iron (Fe0)/H2O2) and weak magnetic field (MWF) for bisphenol A (BPA) abatement was systematically investigated in this study. Though both the Fe0/H2O2and WMF-Fe0/H2O2processes are sensitive to pH, WMF remarkably enhanced BPA removal under the pH range of 3.0–6.0 by 0.5–9.5 times. The characterization of Fe0confirmed the role of WMF in promoting the corrosion of Fe0. Radicals, rather than Fe intermediates, were responsible for BPA degradation. Due to the presence of Cl–as the background ions and its reactivity towards HO•, reactive chlorine species (RCS, i.e., Cl•and Cl2•−) were produced and considerably contributed to BPA degradation. In addition, ~37% and 54% of degraded BPA was ascribed to RCS in the presence of 2 and 100 mM of Cl−, respectively. However, 1.9 mg/L of ClO3−was detected in the presence of 2 mM of Cl−in the WMF- Fe0/H2O2process. HCO3−could diminish ClO3−generation significantly through transforming RCS. The concentration of ClO3−decreased by 74% and 82% with dosing 1 and 10 mM HCO3−, respectively. The results of this study suggest that the WMF-Fe0/H2O2process is a promising approach for BPA removal.Keywords:bisphenol A;zero-valent iron;hydrogen peroxide;weak magnetic field;chloride
研究领域:
环境科学
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化学工程
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高影响因子
TALANTA
·
2017
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IF 4.162
Shiqiang Cui,Shuqing Gu,Yaping Ding,Jiangjiang Zhang,Zhen Zhang,Zongqian Hu
Hollow mesoporous CuCo 2 O 4 (meso-CuCo 2 O 4 ) microspheres were successfully synthesized by decomposing metal-organic frameworks (MOFs) as the template. The as-prepared CuCo 2 O 4 microspheres were first simultaneously used for H 2 O 2 biosensing and glucose biofuel cell (GFC) as the enzyme mimic . The resulting of meso-CuCo 2 O 4 displayed not only excellent catalytic performances to H 2 O 2 including a super-fast response time (within 2 s), a super-high sensitivity (654.23 μA mM −1 cm −2 ) and a super-low detection limit (3 nM at S/N = 3) on the sensor, but also great values in GFC as anode material with an open circuit voltage of 0.85 V, a maximum power density of 0.33 mWcm −2 and a limiting current density of 1.27 mAcm −2 , respectively. The preeminent catalytic abilities to H 2 O 2 and glucose may be attributed to the surpassing intrinsic catalytic activity of CuCo 2 O 4 and large specific area of mesoporous structure. These significant findings deriving from this work not only provided a novel exploration for the fabrication of hollow spherical mesoporous bimetallic oxides, but also promoted the development of the supersensitive detection of H 2 O 2 and non-enzymatic biofuel cell.
研究领域:
材料科学
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生物传感
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电化学能源
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DOI
PubMed
高影响因子
JOURNAL OF ETHNOPHARMACOLOGY
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2020
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IF 3.69
Liping Wang,Qiangwei Chen,Suqi Zhuang,Yuying Wen,Wanqiu Cheng,Zhijun Zeng,Tao Jiang,Chunping Tang
Ethnopharmacological relevance Anoectochilus roxburghii ( A. roxburghii ) is a popular folk medicine in many Asian countries, which has been used traditionally for treatment of some diseases such as diabetes, tumors, hyperlipemia , and hepatitis. The ethanol extract from A. roxburghii was recently shown to exert better ability to scavenge free radicals in vitro and possess antioxidant on natural aging mice in vivo . Aim of the study This study is to characterize the chemical composition, and investigate the protective effect of the A. roxburghii flavonoids extract (ARF) against hydrogen peroxide (H 2 O 2 )-induced oxidative stress in LO2 cells in vitro and D-galactose (D-gal)-induced aging mice model in vivo , and explore the underlying mechanisms. Materials and methods The chemical components of the flavonoids extract fro m A. roxburghii were detected by ultraperformance lipid chromatography coupled with quadrupole-time-of-flight mass spectrometry (UPLC-QTOF-MS/MS). H 2 O 2 was used to establish an oxidative stress model in LO2 cells. Cytotoxic and protective effects of ARF on the LO2 cells were determined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method. Moreover, the levels of superoxide dismutase (SOD), glutathione peroxidase (GSH-PX), and malondialdehyde (MDA) in cell supernatants were measured by commercial reagent kits. Kun-Ming mice were induced to aging with D-gal (400 mg/kg, BW) by subcutaneous injection for 58 days. From the 28th day to the 58th day of D-gal treatment, ARF (122.5, 245 and 490 mg/kg, BW) and vitamin E (100 mg/kg, BW) were orally administrated to aging mice once a day for consecutive 30 days. After 25 days of the treatment with ARF, learning and memory were assessed using Morris Water Maze (MWM). At the end of the test period, the animals were euthanized by cervical dislocation , and the levels of SOD, GSH-PX, and MDA in serum, liver homogenates and brain homogenates were measured. The levels of monoamine oxidase (MAO) and acetylcholinesterase (AchE) were determined in brain homogenates. Skin and liver histopathological morphology were observed by H&E staining. Furthermore, antioxidant-related gene expression levels in the liver were carried out by quantitative real-time polymerase chain reaction (qRT-PCR). Results Nine flavonoids were identified in the extracts of A. roxburghii . In vitro assay, a high concentration of ARF (>612.5 μg/ml) reduced the survival rate and had toxic effects on LO2 cells. In addition, ARF (245 μg/ml, 490 μg/ml) and Vitamin C (200 μg/ml) markedly inhibited generations of MDA and increased activities of SOD, GSH-PX in H 2 O 2 -induced LO2 cells supernatants. In vivo assay, ARF (122.5 mg/kg, 245 mg/kg and 490 mg/kg) and Vitamin E (100 mg/kg) not only ameliorated learning and memory ability but also improved skin and liver pathological alterations. Strikingly, ARF significantly decreased MDA and MAO levels, markedly enhanced antioxidant enzyme (SOD and GSH-PX) activities. Further, compared to the D-gal group, ARF could obviously up-regulate glutathione peroxidase-1 (GPx-1) and glutathione peroxidase-4 (GPx-4) mRNA levels. Conclusions These findings suggested that ARF protects LO2 cells against H 2 O 2 -induced oxidative stress and exerts the potent anti-aging effects in D-gal aging mice model, which may be related to the inhibition of oxidative stress. Flavonoid compounds may contribute to the anti-oxidative capability and modulating aging.
研究领域:
药理学
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生物化学
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细胞生物学
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老年学
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民族药理学
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DOI
PubMed
高影响因子
Journal of Materials Chemistry B
·
2024
·
IF 6.1
Sijie Zhang,Sameer Hussain,Yuhai Tang,Kaili Wang,Xingyan Wang,Long Zhang,Yuheng Liao,Chen Wang,Yi Hao,Ruixia Gao
Nanoagents for chemodynamic therapy (CDT) hold a promising future in the field of antimicrobials, especially copper peroxide (CuO2) (CP) nanomaterials which have garnered significant attention due to their ability to self-supply H2O2. Nevertheless, the poor stability of CuO2 remains a critical challenge which restricts its practical application in the antibacterial field. In this study, an advanced nano-antimicrobial system HA-CP@Fe3O4 with enzyme-responsive properties is developed by coating hyaluronic acid (HA) on CuO2-loaded iron tetraoxide nanoparticles. The coating of HA not only stabilizes the CuO2 nanomaterials but also provides responsiveness towards the enzyme hyaluronidase, which is typically secreted by some bacteria. The outer layer of HA in HA-CP@Fe3O4 undergoes decomposition in the presence of hyaluronidase-secreting bacteria, resulting in the release of CuO2@Fe3O4. The released CuO2@Fe3O4 then self-supplies H2O2 and generates reactive oxygen species (ROS) within the infected microenvironment through Fenton and Russell effects, to ultimately achieve effective and precise antimicrobial activity. Simultaneously, the magnetic property provided by Fe3O4 allows the substance to be directed towards the infection site. Both in vitro and in vivo tests demonstrated that HA-CP@Fe3O4 exhibited excellent antimicrobial capabilities at low concentration (30 μg mL−1), exceptional biocompatibility and the ability to accelerate wound healing. The findings of this work offer a new and promising approach for targeted and precise CDT.
研究领域:
纳米技术
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生物医学工程
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抗菌治疗
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伤口愈合
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材料科学
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DOI
PubMed
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
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2018
·
IF 11.698
Xia Li,Shanshan Liu,Di Cao,Ran Mao,Xu Zhao
In this work, a self-driven photocatalytic fuel cell (PFC) system was constructed, which consisted of a noble metal-free Cu 2 O/CuO photocathode and a semi-transparent BiVO 4 photoanode. The proposed PFC system was used for the degradation of phenol and the removal efficiency of phenol using BiVO 4 -Cu 2 O/CuO system was higher than the PFC using Pt cathode (BiVO 4 -Pt, 67.3%) and bare Cu 2 O cathode (BiVO 4 -Cu 2 O, 84.6%). The short circuit photocurrent of the BiVO 4 - Cu 2 O/CuO system was 0.30 mA cm −2 , which was higher than the sum of photocurrents generated by the other two photoelectrodes. This could be attributed to the self-driven bias induced by the good match of Fermi levels (E F s) between the BiVO 4 and the heterojunction Cu 2 O/CuO electrode. The addition of 5 mM H 2 O 2 to the PFC system greatly enhanced the degradation process, with the pseudo-first-order kinetic rate constant increased from 0.136 to 2.568 h -1 after the addition of H 2 O 2 . Compared with traditional Fenton and Cu-based Fenton-like process, the PFC-H 2 O 2 system has advantages of the broad working pH range (4–7), zero formation of ferric hydroxide sludge and less copper leaching. The X-ray photoelectron spectroscopy (XPS) analysis confirmed the cycle between Cu(I) and Cu(II) on the surface of Cu 2 O/CuO photocathode, indicating that a Fenton-like reaction had occurred on Cu 2 O/CuO photocathode. The H 2 O 2 was activated by both the photo-generated electrons and the Cu 2 O/CuO cathode, which further increased the degradation efficiency of phenol. Furthermore, a high stability was exhibited by the H 2 O 2 -PFC system.
研究领域:
环境科学
·
材料科学
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DOI
高影响因子
危险品化学品经营许可证（带存储）