BIOELECTROCHEMISTRY
·
2026
·
IF 4.9
Zijie Pi,Yuanyuan Zhang,Rongqin Yang,Lin Liu,Yu Huang,Yingchi Wu,Tao Gou,Honghao Kang,Tao Zhang,Xiaoling Yang,Xiaoling Liao
A high-performance nanozyme electrochemical sensor was engineered for the sensitive detection of hydrogen peroxide (H 2 O 2 ). The sensor is based on a synergistic ternary nanocomposite of ZIF-8, reduced graphene oxide (RGO), and platinum nanoparticles (Pt NPs). In this design, the Pt NPs serve as the catalytic centers with intrinsic peroxidase-like activity, effectively mimicking natural enzymes to catalyze the electrochemical reduction of H 2 O 2 . This nanocomposite was immobilized on a glassy carbon electrode (GCE) via a combined drop-casting and electrodeposition strategy. Morphological and structural analyses using scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), and X-ray photoelectron spectroscopy (XPS) confirmed the successful fabrication of a uniform nanocomposite architecture. Systematic optimization revealed that the sensor exhibited excellent detection performance for H 2 O 2 , with a sensitivity of 22.3 μA mM −1 cm −2 ( n = 4), a detection limit as low as 59 nM (S/N = 3), a limit of quantification of 0.197 μM, and a linear range of 62 nM–13.07 mM, exhibiting good selectivity and reproducibility. Importantly, the sensor was successfully applied for the real-time, in-situ monitoring of H 2 O 2 released from zebrafish embryos under cadmium ion (Cd 2+ ) induced oxidative stress. This work offers a promising tool for the early assessment of heavy metal-induced oxidative damage.
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高影响因子
ACS Applied Materials & Interfaces
·
2026
·
IF 7.8
Nail Aminov,Huan Liu,Decheng Meng,Liran Zhu,Xiaohan Guo,Cong Li,Xiaoqing Ye,Huanjun Li
Hair loss remains a prevalent dermatological concern with limited options for targeted, sustained transdermal therapy. Conventional topical formulations of minoxidil (MXD) suffer from poor skin penetration, rapid clearance, and low patient compliance. To address these limitations, we developed a three-dimensional-printed, dissolving microneedle (MN) system featuring a novel layered design: a recyclable polymerizable deep eutectic solvent (PDES) base and detachable, pH-responsive tips loaded with MXD-encapsulated ZIF-8 nanoparticles. This design allows for rapid insertion and dissolution of the drug-loaded needle tips, enabling the sustainable recovery and reuse of the PDES base through a simple ethanol-based regeneration protocol. The MNs exhibited excellent print fidelity, mechanical integrity (>50 mN fracture force), and skin penetration capability, along with minimal cytotoxicity and hemolysis. In vitro and in vivo evaluations confirmed pH-triggered drug release and potent hair regrowth performance in a cyclophosphamide-induced alopecia mouse model. Histological analysis revealed enhanced hair follicle density and demonstrated minimal systemic toxicity, highlighting its safety profile. Overall, this layered dissolving-recyclable MN platform for pH-triggered delivery of ZIF-8-encapsulated MXD represents a promising, sustainable strategy for transdermal delivery to treat hair loss.
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Journal of Water Process Engineering
·
2022
·
IF 7.34
Mengjie Fu,Chun Wang,Guangwu Sun,Changfa Xiao,Ying Ding
3D flower-like UiO-66-NH 2 @ZiF-8 (UZ) nanoparticles have porous structural properties and multifunctional functional groups exposed on the surface, which provide significant advantages in improving compatibility with polymers and exceptional molecular sieve performance. Poly( p -phenylene terephthamide) PPTA is an acid/alkali resistant porous membrane material. However, the preparation of highly permeable and selective nanofiltration (NF) membranes is still a challenging problem due to the low permeability of PPTA NF membranes. Therefore, in this study, PPTA/UiO-66-NH 2 @ZiF-8 (PUZ) membranes were prepared using spacer spray-assisted interfacial polymerization. It was investigated that the effects of different additions of 3D flower-like UZ nanoparticles on the physicochemical properties and structure of PUZ membranes. The results showed that the polyamide structures with different morphologies were formed on the PUZ membranes surface by depositing 3D flower-like UZ nanoparticles at a spraying frequency of 12 min −1 . When 1.3 g/L of 3D flower-like UZ nanoparticles were interval sprayed, the PUZ4 membranes surface showed a unique doughnut-like structure and featured tubular and doughnut-like interconnections. PUZ4 membranes exhibited 4.4 times higher permeance and maintained excellent dye rejection (methylene blue dye permeance up to 58.23 L/m 2 ∙h∙MPa and methylene blue dye rejection of 99.60 %) compared to pristine PPTA NF membranes (methylene blue dye permeance up to 13.25 L/m 2 ∙h∙MPa and methylene blue dye rejection of 92.10 %). In addition, the modified PUZ4 membranes had a great antifouling performance with a recovery ratio of 99.43 % for more than 6 cycles and a high rejection rate of 98.51 % at 0.1 MPa.
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ChemElectroChem
·
2022
·Vol. 9
·期 15
·e202200438
·
IF 4.782
Beibei Yang,Mengjiao Shao,Yufeng Xu,Yanyan Du,Hualing Yang,Duan Bin,Baohong Liu,Hongbin Lu
Graphical A novel electrochemical sensor based on core-shell ZIF-8@ZIF-67-derived Co nanoparticles/N-doped carbon nanotube polyhedron composites has been designed for the efficient determination of antibiotic drug chloramphenicol. In this work, we developed a highly selective detector towards the antibiotic drug chloramphenicol (CAP) using Co nanoparticle, which are grown in situ on N-doped carbon nanotube polyhedra (Co@NCNP), which are obtained by a pyrolysis strategy derived from core-shell ZIF-8@ZIF-67. Physical characterization verified that metal-organic framework (MOFs)-derived Co@NCNP nanocomposites present a nanotube structure on their mesoporous polyhedron surface. As a result, the as-prepared Co@NCNP can be used as a sensitive electrochemical sensor for chloramphenicol detection, and the modified electrode is also studied by electrochemical methods such as electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), and differential pulse voltammetry (DPV). When compared with single ZIF-67-derived electrode, the Co@NCNP displays a higher electrocatalytic activity in the presence of chloramphenicol. Moreover, an excellent performance with a linear response range of 5–268.83 μM and a low detection limit of 0.5 μM (S/N=3) is observed for the Co@NCNP modified electrode. Finally, the fabricated chloramphenicol sensor achieves a good anti-interference ability, stability, excellent repeatability, and remarkable reproducibility. The sensor also could be applied in human serum to determine of chloramphenicol with a satisfactory result.
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Nanomaterials
·
2021
·Vol. 11
·期 10
·2491
·
IF 5.076
Ruiying Wang,Mengran Lou,Jie Zhang,Zhipeng Sun,Zhiqian Li,Pengtao Wen
It is of prime importance to develop anode electrocatalysts for direct methanol fuel cells (DMFCs) with good performance, which is critical for their commercial applications. Metal-organic framework (MOF)-derived carbon materials are extensively developed as supports of catalysts. Herein, Co embedded nitrogen-doped carbon nanotube hollow porous carbon (Co-NCNT-HPC) derived from MOFs have been fabricated, which were synthesized by pyrolyzing at an optimized temperature of 800 °C using ZIF-8@ZIF-67 as a precursor. The presence of ZIF-8@ZIF-67 ensures the doping of nitrogen and the large specific surface area of the support materials at high temperatures. A Pt/Co-NCNT-HPC800 sample, which was synthesized using Co-NCNT-HPC800 as a support, showed an enhanced mass activity of 416.2 mA mg−1Ptfor methanol oxidation reaction (MOR), and the onset potential of COadoxidation of 0.51 V, which shifted negatively about 0.13 V compared with Pt/C (20%). Moreover, the Pt/Co-NCNT-HPC800 sample exhibits high stability. This work provides a facile strategy for MOF-derived carbon materials to construct advanced electrocatalysts for MOR.Keywords:metal-organic frameworks;N-doped carbon nanotube;hollow porous carbon;Pt-based catalysts;direct methanol fuel cells
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2021
·
IF 3.764
Shahid Hussain,Haifeng Dong,Yanqiang Zhang,Guoxiong Zhan,Shaojuan Zeng,Huifang Duan,Xiangping Zhang
The efficient capture of carbon dioxide (CO2) has industrial, economic, and environmental significance. Here, CO2 capture performance in terms of CO2/CH4 selectivity for the zeolitic imidazolate framework (ZIF-8) is enhanced by impregnation of 1-n-butyl-3-methylimidazolium dicyanide [BMIM][DCA]. The preparation of ionic liquids (ILs)/ZIF-8 composites, their comprehensive characterization, and the impact of IL impregnation are all investigated. The crystal structure and morphology of ZIF-8 remained intact even after the impregnation of ILs, according to X-ray diffraction and scanning electron microscopy studies. The infrared spectroscopy known as Fourier transform infrared spectroscopy determines the interaction between ILs and ZIF-8 in the composite. The isotherm fitting was also performed by dual site Langmuir models, which showed good agreement with the experimental results. The CO2/CH4 selectivity results demonstrated that the ideal selectivity for the IL-impregnated ZIF-8 composite has five times higher selectivity than pristine ZIF-8 at 0.05 bar which is the highest reported selectivity. The normalized selectivity of this type of IL/ZIF-8 composite is also higher. This study suggested that the IL/MOF composite with a tunable structure have a strong potential for enhanced acid gas separation performance to meet the environmental challenges.
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高影响因子
ANALYTICAL LETTERS
·
2020
·
IF 1.467
Yufeng Hu,Junpeng Zhang,Gang Li,Hanwen Xing,Minghuo Wu
Chromium (VI) [Cr(VI)] is considered to be a serious environmental pollutant because of its highly carcinogenic and mutagenic properties. In this study, we fabricated fluorescent probes for Cr(VI) detection by encapsulating cadmium telluride quantum dots (CdTe QDs) into zeolitic imidazolate framework-8 (ZIF-8). The obtained composites, designated as CdTe QDs@ZIF-8, were able to sense Cr(VI) through the combined action of fluorescence dynamic and static quenching. Under the optimum conditions, the obtained CdTe QDs@ZIF-8 composites showed high selectivity and sensitivity toward Cr(VI). The fluorescence intensity of the CdTe QDs@ZIF-8 composites decreased as the concentration of Cr(VI) increased across from the range of 2.5 to 40 μM with a detection limit of 0.06 μM. The CdTe QDs@ZIF-8 composites were successfully applied to determine Cr(VI) in tap water and seawater samples; the average recoveries of Cr(VI) at different spiking concentration levels ranged from 94.0% to 104.1% with relative standard deviations below 4.8%. This work provides a novel fluorescent detection method for Cr(VI) and discrimination between Cr(VI) and Cr(III), which can be used for rapid recognition and determination of Cr(VI) in complex matrices.
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高影响因子
RSC Advances
·
2019
·Vol. 9
·期 60
·35189-35196
·
IF 3.049
Yi-Wei Cui,Hai-Huan Zhang,Shi-Yong Yu
Efficient C–ZnS/ZnMoO4@MoS2 and C–ZnS/MoS2 nanocomposite photocatalysts, using ZIF-8 derived C–ZnO as a precursor were successfully synthesized using a simple one-pot procedure. This is the first application that involves transforming ZIF-8 into C–ZnMoO4 for photocatalysis. The C–ZnS/ZnMoO4@MoS2 and C–ZnS/MoS2 heterostructures were characterized by X-ray diffraction, UV-vis, X-ray photoelectron spectroscopy, electrochemical impedance spectroscopy, photocurrent measurements, scanning electron microscopy and transmission electron microscopy. The ZM2 sample of C–ZnS/ZnMoO4@MoS2 exhibited enhanced photocatalytic activity of about 2.9 times as high as that of ZIF-8 derived C–ZnO in the reduction of tetracycline hydrochloride, and also showed obvious photocatalytic activity 1.81 and 3.33 times as high as that of a ZM3 sample of C–ZnS/MoS2 and ZIF-8 derived C–ZnO in the degradation of RhB, respectively. The improved photodegradation activity is a result of the heterogenous structure and the tighter contact between C–ZnS and C–ZnMoO4 compared with the physical contact of general heterogenous photocatalysts. The C–ZnS/ZnMoO4@MoS2 heterostructure photocatalyst is expected to be a new type of nanomaterial for the degradation of pollutants from wastewater.
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高影响因子
ANALYTICA CHIMICA ACTA
·
2019
·
IF 5.256
Kang Zou,Yamin Fu,Ruiying Yang,Xiaohua Zhang,Cuicui Du,Jinhua Chen
By direct calcination of Cu 2+ -doped ZIF-8 in oxygen atmosphere, a new photoelectric material, CuO–ZnO heterojunction , was prepared. The morphology and structure were investigated in detail by several methods, such as scanning electron microscopy, transmission electron microscopy , nitrogen adsorption-desorption method and X-ray diffraction. Under visible light irradiation , CuO–ZnO heterojunction exhibits excellent PEC behavior in aqueous media with the presence of ascorbic acid (AA) and dissolved oxygen at −0.3 V. Taking the CA125-antibody functionalized CuO–ZnO heterojunction (CuO–ZnO-Ab 2 ) as a signal source, a novel photoelectrochemical (PEC) immunosensing platform was developed for ultrasensitive assay of CA125. Because of the target-induced introduction of photoelectric material to the sensing platform, the proposed PEC immunosensor has excellent performance for CA125 assay: near-zero background noise, wide linear response range (1 × 10 −5 U/mL to 100 U/mL) and low detection limit (3.16 × 10 −6 U/mL). The developed CuO–ZnO heterojunction and the related PEC sensing platform may have promising applications in ultrasensitive and highly accurate monitoring of various proteins in bioanalysis and disease diagnosis.
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2023
·
IF 9.9
Yingwei Li,Shiwei Weng,Shasha Wang,Guojie Zhang,Fusheng Liu,Mengshuai Liu
The development of novel catalytic materials that integrate multifunctional sites has significant implications for expanding the utilization of CO 2 resources. However, simultaneously achieving high activity and stability remains a formidable challenge. In this study, a series of ZIF-8(Zn/Co)@g-C 3 N 4 nanocomposites were prepared by employing a thermo-physical compounding strategy that involved the combination of nitrogen-rich graphitic carbon nitride (g-C 3 N 4 ) nanosheets with ZIF-8(ZnCo). The influences of different compositions of g-C 3 N 4 and ZIF-8(Zn/Co) on the catalyst structure were systematically investigated. Subsequently, the catalytic activities of these nanocomposites towards the cycloaddition reaction between CO 2 and epoxide were examined under different conditions. The presence of abundant Lewis base sites in g-C 3 N 4 facilitates CO 2 activation, while multiple Lewis acid sites in ZIF-8(Zn/Co) enable efficient epoxide activation. By working synergistically with a co-catalyst, tetrabutylammonium bromide (TBAB), CO 2 and epoxides can be efficiently reacted to synthesize the corresponding cyclic carbonates under mild or even atmospheric pressure conditions. The catalytic reaction conditions were optimized, and both the catalyst's recycling performance and the scope of epoxides with various substituents were investigated. The integration of g-C 3 N 4 and ZIF-8(Zn/Co) endows the catalytic material with exceptional structural stability and remarkable catalytic activity, thereby providing a new platform for highly efficient CO 2 conversion.
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高影响因子
CRYSTENGCOMM
·
2023
·Vol. 26
·期 1
·70-79
·
IF 3.1
Zhen Li,Bo He,Shaokun Tang
Hierarchically porous metal–organic frameworks (HP-MOFs) possess the advantages of the high porosity of MOFs and unique properties, such as a wide pore size range. Hierarchically porous ZIF-8 (HP-ZIF-8) was facilely fabricated via a one-step method in supercritical CO2 (scCO2) using a competitive ligand. The mesoporous structure and morphology of HP-ZIF-8 can be easily adjusted by changing the dosage of competing ligands and the reaction temperature. When the molar ratio of zinc acetylacetonate, 2-methylimidazole, and 2-butyl-1H-imidazole was 1 : 1 : 6, the HP-ZIF-8 with micropores (1.7 nm) and mesopores (3.9–30 nm) was synthesized at 50 °C and 30 MPa for 3 hours with excellent reproducibility. The as-synthesized ZIF-8 shows a high activity for CO2 adsorption, and the CO2 equilibrium adsorption capacity reached up to 1.49 mmol g−1 sorbent at 25 °C and 0.1 MPa. Moreover, the CO2 equilibrium adsorption capacity of HP-ZIF-8 was maintained at 1.36 mmol g−1 sorbent after 7 cycles.
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MICROCHEMICAL JOURNAL
·
2023
·
IF 4.8
Conglin Zhang,Yinhui Yi,Yifan Zhou,Ruiyong Zhou,Gangbing Zhu
Electrochemical sensing is the commonly used method for the detection of heavy metal silver ion (Ag + ), while the conventional electrochemical sensors generally require the existence of electrode modifications and even electrodeposition step coupled with a single-mode readout. Herein, by preparing ZIF-8 organometallic frame load with platinum nanoparticles (Pt@ZIF-8) as nanozyme and o-phenylenediamine (OPD) as colorless substance, taking advantage of the superior peroxidase activity of Pt@ZIF-8 that can catalyze the oxidation of OPD to product electroactive/yellow 2,3-diaminophenazinc and the target-inhibited effect towards nanozyme activity from Ag + , a homogeneous electroanalysis coupled with colorimetry (HEA-CM) dual-mode sensing platform was designed for the first time to detect Ag + . Furthermore, the colorimetric images were converted on a smartphone to digital signals for the quantitative analysis. The designed strategy could offer multiple advantages such as electrodeposition-free, modification-free and dual channel readout. After investigating the sensing mechanism and experimental parameters, the analytical performance of the designed strategy was evaluated, obtaining extremely low detection limit (0.034 nM), reliable recovery rate (99.61 %-101.6 %) and wide linearity. This work offered an effective method for the simple, sensitive, rapid, accurate and multiplexed determination of Ag + , and also opened a new pathway for the detection of other heavy metals based on HEA-CM dual-mode strategy.
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