JOURNAL OF MATERIALS SCIENCE
·
2024
·Vol. 59
·期 19
·8287-8297
·
IF 3.5
Liu Yang,Jiang Lu,Jiang Ruonan,Liu Huanhuan
Researchers are showing a great deal of interest in hydrogels due to the presence of high-water content, self-healing variants. Despite this, research into the development of smart hydrogels that have the combination of toughness, self-healing, and responsiveness to external stimuli is still lacking. Here, tough, and intelligent nanocomposite (NC) hydrogels have been developed by utilizing modified nano-crosslinker by means of gold-selenium (Au-Se) coordination interaction. The NC hydrogels demonstrate remarkable elasticity and strength, even when exposed to notches. With the optimal formulation, the nanocomposite hydrogel can achieve a maximum elongation of 1970%, a maximum fracture stress of 2.48 MPa, and a toughness of up to 9.95 MJ/m 3 , thanks to the dynamic gold crosslinks with improved branching. The presence of this structural attributes facilitates efficient energy dissipation within the hydrogel system. Combining Au-Se interaction as a healing element and the remarkable optothermal effect of nanoparticles, NC hydrogels can be quickly self-healed in near-infrared light exposure of 2 min, achieving a self-healing efficiency of 91%. Additionally, the hydrogels demonstrate repair potential when exposed to microwave irradiation, acid solution, and ultrasound stimulus. Moreover, a multi-responsive hydrogel composed of photothermal gold nanostructures can serve as a light-controlled drug carrier, which has smart drug release ability under external light stimulation. The advantageous properties of hydrogel make it a great option for biomedical and engineering fields.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2025
·
IF 4.7
Xinrong Li,Shuliang Chen,Xianzhi Hu,Futing Zi
A key challenge in the recovery of Au ions from thiosulfate gold leaching solutions is the design of adsorbents with abundant active adsorption sites, exhibiting high affinity and selectivity toward Au(I), thus enabling its fast, high-purity, and large-capacity recovery. Guided by theoretical calculations, in this study a polychloromethylstyrene (PCMS) material capable of supplying additional charges was functionalized by triethylamine (TEA) to selectively recover gold from a thiosulfate leaching solution. The adsorption of Au(S₂O₃)₂³⁻ onto the functionalized PCMS–TEA followed pseudo-second-order kinetics and was consistent with the Langmuir isotherm model, suggesting a single-molecular-layer chemisorption process. PCMS–TEA exhibited a significant Au-ion loading capacity (81.50 kg/t), highlighting the potential of benzene rings to enhance the charge intensity of ionic adsorbents. Furthermore, PCMS–TEA exhibited good Au-ion selectivity in a copper–ethylenediamine–thiosulfate Au leaching solution. The adsorption mechanism of Au ions on PCMS–TEA involved ion exchange between Cl − in the adsorbent and Au(S 2 O 3 ) 2 3− complex ions. The visual analysis of density functional theory results, based on the Multiwfn and Visual Molecular Dynamics programs, confirmed the presence of a weak interaction between PCMS–TEA and Au(S 2 O 3 ) 2 3− , dominated by van der Waals forces. After five desorption cycles, the adsorption rate of Au ions was approximately 90%, and NaCl was used as the elution reagent. This study introduces a promising adsorbent for the selective recovery of Au ions from thiosulfate Au leaching solutions.
✓ 已验证
DOI
高影响因子
Materials Today Physics
·
2025
·
IF 9.7
Mingliu Li,Hongbin Wang,Shuo Yang,Lin Yang,Peng Li,Jiangang Ma,Yichun Liu
High sensitivity and fast response dual-band photodetectors (PDs) covering the deep-ultraviolet (DUV) to visible spectrum are highly desired for industrial and scientific applications. Herein, a sandwich-architecture PD covering the range from DUV to visible was prepared by stacking a β -Ga 2 O 3 DUV absorbing layer, interdigitated Au electrodes, and a Cs 2 AgBiBr 6 (CABB) visible absorbing layer. At 5 V bias voltage, the sandwich-architecture PD achieves responsivities of 37.74 mA/W at 240 nm and 0.07 mA/W at 450 nm with microsecond response time, respectively, which is superior to the PDs using monolayer β -Ga 2 O 3 or CABB. Furthermore, it demonstrates self-powered dual-band detection capability with maximum responsivity of 8.13 mA/W. Enhanced performance arises from two synergistic mechanisms: a vertical built-in electric field at the β -Ga 2 O 3 /CABB interface spatially separates photogenerated carriers, while a higher hole mobility in CABB facilitates the charge collection under a lateral bias field between Au electrodes. Importantly, the β -Ga 2 O 3 /Au/CABB PD demonstrates high-resolution images under 240 nm and 450 nm illumination. This work provides a route for developing high-performance DUV-visible dual-band photodetectors, highlighting their potential for advanced multispectral imaging applications.
✓ 已验证
DOI
高影响因子
Advanced Healthcare Materials
·
2025
·
IF 9.6
Chaofan Yao,Yu Zhao,You Wu,Haoming Wang,Hongbin Li,Jinmei He,Li Liu,Yudong Huang,Feng Cheng
Bacterial infections remain a critical challenge in wound care, demanding advanced multifunctional materials for effective treatment. Here, this work presents a 3D-printable hydrogel (STFWA) integrating a Schottky heterojunction and dual-network architecture for synergistic photothermal and photodynamic antibacterial therapy. The hydrogel incorporates W18O49-x@Au nanostructures, where Au nanoparticles are in situ grown on oxygen-deficient W18O49-x (bandgap ≈1.5 eV), forming a Schottky junction that enhances carrier separation and reactive oxygen species (ROS) generation. The dual-network matrix, composed of silk fibroin and tannic acid-Fe3+ (TA/Fe3+), exhibits robust mechanical integrity and hemostatic capability, while silk fibroin enables high-resolution digital light processing (DLP) 3D printing. The co-existence of W18O49-x and Au induces dual localized surface plasmon resonance (LSPR), while TA/Fe3+ contributes to deep coloration, collectively boosting photothermal conversion. Upon near-infrared (NIR) irradiation, the hydrogel exhibits potent antibacterial efficacy against Staphylococcus aureus and Escherichia coli through combined photothermal and photodynamic mechanisms. In vivo studies using a rat model of infected wounds demonstrate accelerated healing, enhanced angiogenesis, and regulated inflammation. This work highlights a nanostructure-enabled hydrogel platform for NIR-activated, synergistic antibacterial therapy with clinical potential in infected wound management.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MOLECULES
·
2019
·Vol. 24
·期 17
·3039
·
IF 3.06
Yijie Mao,Yu Zhang,Wei Hu,Weiwei Ye
Histamine can be formed by enzymatic decarbonylation of histidine, which is an important indicator of seafood quality. A rapid and sensitive assay method is necessary for histamine monitoring. A fluorescence resonance energy transfer (FRET) assay system based on a carbon dot (CD)-modified nanoporous alumina membrane and Fe3O4@Au magnet nanocomposites has been developed for histamine detection in mackerel fish. CDs immobilized on nanoporous alumina membranes were used as donors, which provided a fluorescence sensing substrate for histamine detection. Fe3O4@Au magnet nanocomposites can not only act as acceptors, but also concentrate histamine from fish samples to increase detection sensitivity. Histamine was detected by the fluorescence signal changes of CDs capturing histamine by an immune reaction. The fluorescence signals of CDs were quenched by Fe3O4@Au magnet nanocomposites via the FRET mechanism. With an increase of histamine, the fluorescence intensity decreased. By recording fluorescence spectra and calculating intensity change, histamine concentration can be determined with a limit of detection (LOD) of 70 pM. This assay system can be successfully applied for histamine determination in mackerel fish to monitor the fish spoilage process in different storage conditions. It shows the potential applications of CDs-modified nanoporous alumina membranes and Fe3O4@Au magnet nanocomposites-based biosensors in the food safety area.Keywords:fluorescence resonance energy transfer;CDs;nanoporous alumina membrane;food safety
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Chemical & Biomedical Imaging
·
2025
·
IF 5.7
Qin Zhang,Chen Zhang,Yanan Deng,Huijuan Cao,Cailin Liang,Jie Yang,Jiayao Zhutang,Lin Wei,Lehui Xiao
The development of highly efficient photocatalysts for the utilization of solar energy has been extensively explored in the past few decades. Due to the strong light-matter interaction in plasmonic nanostructures, the combination of plasmonic nanomaterials with other poor light-absorbing catalytic materials presents a promising strategy for expanding the scope of light-driven heterogeneous catalysis. Although the photocatalytic performance of these hybridized structures has been greatly improved, how to regulate the charge carrier transfer efficiency in these heterostructures is still ambiguous. In this work, we prepared a metal–semiconductor core–shell heterostructure through precisely coating a thin layer of CdS onto the gold nanocube (AuNC) surface. A noticeable increase in photoelectrical response from the core–shell structure relative to either AuNCs or pure CdS nanoparticles can be observed in photocurrent generation efficiency, electron lifetime, and charge separation efficiency. More importantly, the photoelectrical responses can be well regulated by changing the semiconductor shell thickness on the nanocube surface. An optimum shell thickness for the light-driven photocatalytic reaction is around 8.3 nm, which exhibits the highest charge carrier transfer efficiency and hot-electron generation rate.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Heshun Jing,Qingtai Xie,Huijuan Su,Yuqi Zhai,Xun Sun,Baorong Duan,Lijun Zhao,Miao Zhang,Caixia Qi,Libo Sun
The research and progress of noble metal catalysts possessing good stability and extended service life holds significant importance in enhancing catalytic efficiency, reducing enterprise costs, and fostering sustainable social development. Here, a hollow magnetic h-Au/PDA@PDA@Fe 3 O 4 catalyst with a double-layer PDA structure was prepared to optimize the stability of gold nanoparticles (NPs) using for the 4-nitrophenol (4-NP) reduction. The research indicates that, despite the initial activity of h-Au/PDA@PDA@Fe 3 O 4 , with a mass-normalized rate ( k’ ) of 176.10 s −1 ·g Au -1 and a Turn Over Frequency (TOF) of 1757 h −1 , being smaller than h-Au/PDA@Fe 3 O 4 with a single-layer structure ( k’ = 461.76 s −1 ·g Au -1 , TOF = 6387 h −1 ), h-Au/PDA@PDA@Fe 3 O 4 exhibits significantly superior stability compared to h-Au/PDA@Fe 3 O 4 . After undergoing 12 cycles of use, the conversion rate of h-Au/PDA@PDA@Fe 3 O 4 decreased by only 4.3 %. After cyclic reaction, the conversion rate of h-Au/PDA@Fe 3 O 4 decreased by as much as 64.8 %. The distinctive hollow double-layer structure of h-Au/PDA@PDA@Fe 3 O 4 , along with the interaction between Au and PDA, contributes significantly to its exceptional activity and stability. The research presented in this paper offers valuable insights and guidance for the suitable construction and industrial application of gold-based nano catalyst with good activity and cyclic stability.
✓ 已验证
产品关联
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2016
·
IF 7.476
Zongbing Li,Xiangmin Miao,Ke Xing,Xue Peng,Aihua Zhu,Liansheng Ling
A novel electrochemical biosensor for Hg 2+ detection was reported by using DNA-based hybridization chain reaction (HCR) coupled with positively charged [email protected] core-shell nanoparticles ((+) [email protected] CSNPs) amplification. To construct the sensor, capture probe (CP ) was firstly immobilized onto the surface of glass carbon electrode (GCE). In the presence of Hg 2+ , the sandwiched complex can be formed between the immobilized CP on the electrode surface and the detection probe (DP) modified on the gold nanoparticles (AuNPs) based on T-Hg 2+ -T coordination chemistry. The carried DP then opened two ferrocene (Fc) modified hairpin DNA (H 1 and H 2 ) in sequence and propagated the happen of HCR to form a nicked double-helix. Numerous Fc molecules were formed on the neighboring probe and produced an obvious electrochemical signal. Moreover, (+) [email protected] CSNPs were assembly onto such dsDNA polymers as electrochemical signal enhancer. Under optimal conditions, such sensor presents good electrochemical responses for Hg 2+ detection with a detection limit of 3.6 pM. Importantly, the methodology has high selectivity for Hg 2+ detection.
✓ 已验证
DOI
PubMed
高影响因子
Biosensors-Basel
·
2022
·Vol. 12
·期 8
·558
·
IF 5.743
Xiawei Dong,Jing Ye,Yihan Wang,Hongjie Xiong,Hui Jiang,Hongbing Lu,Xiaohui Liu,Xuemei Wang
Tumor accurate imaging can effectively guide tumor resection and accurate follow-up targeted therapy. The development of imaging-stable, safe, and metabolizable contrast agents is key to accurate tumor imaging. Herein, ultra-small and metabolizable dual-mode imaging probe Au/[email protected]NCs is rationally engineered by a simple hydrothermal method to achieve accurate FL/MRI imaging of tumors. The probes exhibit ultra-small size (2.5–3.0 nm), near-infrared fluorescence (690 nm), high quantum yield (4.4%), and a better T1nuclear magnetic signal compared to commercial MRI contrast agents. By modifying the folic acid (FA) molecules, the uptake and targeting of the probes are effectively improved, enabling specific fluorescence imaging of breast cancer. Au/[email protected]NCs with good biosafety were found to be excreted in the feces after imaging without affecting the normal physiological metabolism of mice. Intracellular reactive oxygen species (ROS) increased significantly after incubation of Au/[email protected]NCs with tumor cells under 660 nm laser irradiation, indicating that Au/[email protected]NCs can promote intracellular ROS production and effectively induce cell apoptosis. Thus, metabolizable Au/[email protected]NCs provide a potential candidate probe for multimodal imaging and tumor diagnosis in clinical basic research. Meanwhile, Au/[email protected]NCs mediated excessive intracellular production of ROS that could help promote tumor cell death.Keywords:Au/[email protected]NCs;dual-mode probe;FL/MRI imaging;reactive oxygen species (ROS);cancer theranostics
✓ 已验证
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Hanyue Jiang,Juan Lu,Wenzhuo Wang,Pengfei Han,Guangping Ma,Tengying Ma,Li Tian,Jing Wang
In this study, a porous bimetallic oxide Cu 4 RuO 5 with a high specific surface area was prepared via electrospinning followed by high-temperature calcination. This oxide exhibited a significant electrochemiluminescence (ECL) signal when reacting with S 2 O 8 2− . Utilizing this bimetallic oxide as an ECL material, we constructed a simple solid-state ECL sensor, in conjunction with Au NPs@SiO 2 , for the sensitive detection of tilmicosin in milk. The sensor was constructed using a layered modification approach. Initially, the bimetallic oxide Cu 4 RuO 5 was modified onto the electrode surface. Cu 4 RuO 5 not only serves as a luminescent reagent but also promotes electron transfer within the system due to its large specific surface area and porosity, achieving amplification of the first-stage ECL signal. Subsequently, Au NPs@SiO 2 was modified onto the oxide surface. The SiO 2 shell effectively shields the system from complex matrix interferences while providing a large specific surface area for the immobilization of Au NPs. The Au NPs further accelerate electron transfer, thereby achieving amplification of the second-stage signal. Based on this two-step amplification strategy, the constructed ECL sensor exhibits a linear response range for tilmicosin from 1.0 × 10 −13 to 1.0× 10 −6 mol L −1 , yielding a detection limit of 2.01 × 10 −14 mol L −1 (3σ/m). This sensor combines high sensitivity, good selectivity, and excellent stability, providing a novel method for the rapid determination of antibiotic residues in food, successfully implemented to enable rapid determination of tilmicosin in milk matrices.
✓ 已验证
产品关联
DOI
高影响因子
ACS Nano
·
2025
·
IF 16
Yao Yao,Yue Zhao,Huijuan Zhang,Wenting Pan,Wei Liang,Yijian Jiang,Xinlong Yan,Yinzhou Yan
The development of surface-enhanced Raman spectroscopy (SERS) as an ultrasensitive fingerprint analysis technique in precision medicine requires high-performance SERS substrates with controllable nanostructure (hot-spot) distribution, simple fabrication, superior stability, biocompatibility, and extraordinary optical responses. Unfortunately, fabrication of arbitrary nanostructures with high homogeneity on a large scale for SERS is still challenging. Herein, we report an ultrafast laser parallel fabrication protocol for Au/2D-transition-metal dichalcogenide hybrid SERS biosensors. The leveraged photonic nanojets (PNJs) are generated by a micron-sized microsphere monolayer to simultaneously trigger localized phase transition in 2H-MoTe2, achieving a 1T′-MoTe2 nanopattern array with a density of 1 million per mm2 by a single laser shot. The Au nanoparticle clusters (AuNCs) are subsequently grown in situ from the 1T′ regions, creating a AuNCs on 1T′/2H-MoTe2 (AuNCs@1T’/2H-MoTe2) hybrid SERS substrate. The fabricated feature diameter and overlay accuracy of the patterned AuNCs are 210.1 ± 3.4 and 9.2 ± 1.7 nm, respectively. To eliminate background noise, we designed dimer-AuNCs@1T′/2H-MoTe2 (dAuNCs@1T′/2H-MoTe2), achieving a detection limit of 10–13 M with an enhancement factor of 4.9 × 108 for the methylene blue (MB) analyte. The strong localized surface plasmon resonances in the dAuNCs as well as efficient charge transfers between Au, 2H-MoTe2, and MB contribute to the majority of Raman enhancement. The multiscale dAuNCs@1T′/2H-MoTe2 array provides a powerful SERSome (comprising multiple SERS spectra) platform for therapeutic drug monitoring, by which we successfully identified the metabolic behaviors of living gastric adenocarcinoma cells administered with two drugs, i.e., capecitabine, oxaliplatin, and their combination. The present work establishes opportunities for creating a highly ordered nanopattern array for ultrasensitive SERSome analysis of cell metabolism in cancer therapy.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
·
2020
·Vol. 68
·期 1
·114-120
·
IF 1.554
Hui Xie,Yanyan Niu,Ying Deng,Hui Cheng,Chengxiang Ruan,Guangjiu Li,Wei Sun
In this paper, an electrochemical aptamer sensor was proposed for the highly sensitive detection of mercury ion (Hg 2+ ). Carbon nanofiber (CNF) was prepared by electrospinning and high-temperature carbonization, which was used for the loading of platinum nanoparticles (PtNPs) by the hydrothermal method. The Pt@CNF nanocomposite was modified on the surface of carbon ionic liquid electrode (CILE) to obtain Pt@CNF/CILE, which was further decorated by gold nanoparticles (AuNPs) through electrodeposition to get Au/Pt@CNF/CILE. Self-assembling of the thiol-based aptamer was further realized by the formation of Au-S bond to get an electrochemical aptamer sensor (Aptamer/Au/Pt@CNF/CILE). Due to the specific binding of aptamer probe to Hg 2+ with the formation of T-Hg 2+ -T structure, a highly sensitive quantitative detection of Hg 2+ could be achieved by recording the changes of current signal after reacting with Hg 2+ within the concentration range from 1.0 × 10 −15 mol/L to 1.0 × 10 −6 mol/L and the detection limit of 3.33 × 10 −16 mol/L (3σ). Real water samples were successfully analyzed by this method.
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）