ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
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2017
·Vol. 25
·期 4
·3922-3932
·
IF 2.741
Yi Xiaofeng,Yang Meixia,Mo Liuda,Xu Wenkai,Wang Shuai,He Jiarui,Gu Junjie,Ou Minrui,Xu Xiaoping
Copper in drinking water causes a significant environmental problem. Composite material based on alginate hydrogel has been gaining attention in the field of Cu(II) adsorption. However, alginate-based hydrogel exhibits poor mechanical property and relative low adsorption capacity which limit their application. The present study is devoted to the modification of chitosan/calcium alginate/Fe 3 O 4 (CAF) hydrogel microsphere by NaOH solution for enhancement of Cu(II) adsorption. Results reveal that modification of CAF via NaOH solution significantly improves the mechanical strength and Cu 2+ adsorption capacity of pristine materials. FTIR and XRD analysis confirms that CAF and newly prepared materials (NACAF) are successfully prepared. SEM and EDX are employed to analyze the surface morphology and elemental composition, respectively, both before and after their loading with Cu 2+ . XPS study demonstrates adsorption mechanism is based on chelation and ion-exchange. Compressive stress-strain curves demonstrate NACAF has better mechanical performance than CAF. The adsorption kinetics of the two adsorbents follow a pseudo-second-order model. The equilibrium data were best described by Langmuir isotherm model, and the estimated maximum equilibrium sorption capacity, q
m ,is 261.31 mg/g for the NACAF, which is larger than that of CAF (145.39 mg/g). Hence, NACAF shows excellent mechanical strength and high sorption capacity for Cu 2+ . It has great potential for Cu(II) removal in aqueous solutions.
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FOOD CONTROL
·
2017
·
IF 3.496
Chenjun Zhuang,Yongli Jiang,Yu Zhong,Yanyun Zhao,Yun Deng,Jin Yue,Danfeng Wang,Shunshan Jiao,Haiyan Gao,Hangjun Chen,Honglei Mu
Polyvinyl alcohol (PVA), sodium alginate (SA) and chitosan (CHI) are all biodegradable materials with excellent film-forming properties. This study prepared bilayer films with PVA-CHI film as the outer layer and SA film as the inner layer. Fuzzy comprehensive evaluation was used to study the effects of the SA film formula where nano-cellulose, surfactant, calcium chloride and anti-bacterial agents were added. The performance of the bilayer films was evaluated considering water solubility, water barrier, mechanical and antibacterial properties. And the effects of the coatings on qualities of shell eggs were investigated. The results demonstrated that the bilayer film possessed lower water vapor permeability (WVP) than the single-layer one, and water droplet was more difficult to spread on bilayer film. Increasing the content of SA significantly increased ( p ≤ 0.05 ) the mechanical properties of bilayer film, and the tensile strength (TS) increased 1.8 times when the SA content increased from 1 to 2%. Calcium chloride decreased the film solubility, and Tween 80 reduced the surface tension of the film-forming solution. Moreover, ethyl paraben sodium significantly increased the antibacterial activity of the bilayer film against E.coli and L . innocua , but had negative impact on TS and WVP. According to the orthogonal test L9 (3 4), the optimal formula of SA layer was: SA 1.25%, calcium chloride 0.75%, Tween 80 0.175%, and ethyl paraben sodium 0.125%. In addition, coatings reduced weight loss, and maintained Haugh unit and yolk index of shell eggs during 15 days of storage at 25 °C, especially bilayer coating.
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Marine Drugs
·
2017
·Vol. 15
·期 9
·284
·
IF 3.503
Wenbo Dong,Weiping Li,Yu Chen,Yanchun Ye,Shaohua Jin
In the present work, a fluorescent H2O2biosensor was constructed by encapsulating fluorescent probe Rhodamine B (RhmB) in the hydrophobic cavity of the cyclodextrin (β-CD) and immobilizing catalase (CAT) on the 2-NH2of chitosan (CTS) in a chitosan 6-OH immobilized β-cyclodextrin derivative (CTS-6-CD). The inclusion complex of CTS-6-CD to RhmB (CTS-6-CD-RhmB) was prepared by a solution method. Its structure and inclusion efficiency were determined by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and fluorescence spectroscopy (FL). CAT was immobilized on CTS-6-CD-RhmB to eventually form the functional membrane, CTS-6-CD-RhmB-CAT, via glutaraldehyde crosslinking, which was further characterized by FTIR and FL, and used as a H2O2biosensor. The functional membrane was used to simultaneously oxidize and detect H2O2. The detection condition was optimized as pH 8, a reaction temperature of 25 °C, and an immobilized enzyme concentration of 2 × 10−4mol/L. The fluorescence response of the biosensor exhibited a good linear relationship with the concentration of H2O2in the range of 20 mΜ–300 μM and the detection limit of 10−8mol/L.Keywords:chitosan;catalase;β-cyclodextrin;Rhodamine B;fluorescent biosensor
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INDUSTRIAL CROPS AND PRODUCTS
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2024
·
IF 5.6
Kun Li,Jiaqi Zhang,Yifan Li,Zirong Li,Jun Wang,Yuanyuan Yu,Qiang Wang,Ping Wang
The application of protease as a biocatalyst for the anti-felting finishing of wool has been widely explored. However, commercial proteases tend to hydrolyze the non-keratinized proteins in the cell membrane complex (CMC) layer while removing wool scales, resulting in excessive hydrolysis and unacceptable fiber damage. Herein, chitosan oligosaccharide (COS) was covalently grafted to papain using carbodiimide/N-hydroxysuccinimide (EDC/NHS) to prepare a less-destructive modified protease of Pap-COS. Subsequently, one-bath anti-felting finishing of wool was carried out using reducing agent and Pap-COS, aiming at achieving low shrinkage and reduced strength loss. The results reveal that Pap-COS achieved a larger particle size than native papain, accompanied by a prolongation of its half-life and a decrease in the thermal inactivation rate, demonstrating improved stability. Under the same incubation conditions, the felting shrinkage of wool fabrics treated with papain and Pap-COS was similar (approximately 5 %). In contrast, native papain caused a 20.82 % decrease in fabric strength, while Pap-COS resulted in a substantially lower decrease (8.10 %), meeting the requirements of commercial woolen products. Furthermore, the dyeing performance and wearability of the Pap-COS-treated wool fabrics were also dramatically improved. The present work provides an alternative for eco-friendly shrink-resistant finishing of woolen textiles in wool industry.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Juan Wang,Junyu Wang,Jun Zhang,Haoran Ye,Dawei Wang,Ling Tao,Yongchao Yao,Ying Chen,Xiangchun Shen
As a notoriously incurable tumor, triple-negative breast cancer (TNBC) exhibits significant sensitivity to ferroptosis and the glutathione (GSH) antioxidant defense system plays a crucial role in its progression. Herein, we report a bimetallic chitosan/hyaluronic acid nanoparticle (5FCN, with a Fe/Cu mass ratio of 5:5) that employs a self-amplified dual mechanism of ferroptosis and cuproptosis for TNBC therapy. Hyaluronic acid in 5FCN specifically binds to the overexpressed CD44 receptor on TNBC cells. This allows 5FCN to enter cells via receptor-mediated endocytosis, then release metal ions in acidic environments. Released Fe 3+ and Cu 2+ react with GSH in tumor cells, weakening the antioxidant system and producing Fe 2+ and Cu + . These ions trigger Fenton/Fenton-like reactions with H 2 O 2 , generating toxic hydroxyl radicals (·OH) to boost ferroptosis. Meanwhile, high-valent Cu 2+ and Fe 3+ are produced, forming a cycle for GSH depletion and ·OH generation. As H 2 O 2 depletes, the rising Cu + level in cells causes lipoylated protein aggregation, amplifying cuproptosis. In vitro and in vivo studies demonstrated that 5FCN exhibited superior cell-killing efficacy against TNBC with few side effects. Collectively, 5FCN represents a potential drug to self-amplify ferroptosis/cuproptosis in TNBC.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Haoyang Xu,Yage Zheng,Yue Shen,Chaoqun Mu,Zhiqiang Zhang,Zhixian He,Yao Wang,Juanqin Xue,Liang Zhang
In this work, the photocatalyst BiOCOOH/BiYO 3 /Chitosan (CS) was prepared by using CS as the carrier and adsorbent. The performance of the material was studied through the photocatalytic degradation of tetracycline (TC) in water. Theoretical calculations and experiments demonstrate that the formation of BiOCOOH/BiYO 3 heterojunctions improves the separation of photogenerated carriers and the absorption of visible light by the material. The introduction of CS improves the difficulties in material recovery, demonstrating exceptional degradation ability for TC under the action of adsorption and photocatalysis. Adsorption kinetics studies indicate that the adsorption of TC by BiOCOOH/BiYO 3 /CS fits the pseudo-second-order model better, while the adsorption at different concentrations of TC is more suitably described by the Freundlich isotherm model. The synthesis of BiOCOOH/BiYO 3 /CS was confirmed by the analysis of XRD, XPS, and FTIR. UV–vis DRS showed that the synthesis of BiOCOOH/BiYO 3 /CS broadened the range of light absorbed by the material. The testing results of PL and transient photocurrent density indicate that BiOCOOH/BiYO 3 exhibits a higher efficiency in separating photogenerated charge carriers. After 5 cycles of reuse, the degradation efficiency can still reach 90 % of the initial efficiency, indicating that CS-based photocatalytic composite catalysts have practical application potential in the field of water pollution treatment.
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FOOD HYDROCOLLOIDS
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2024
·
IF 11
Peini Li,Yiqing Deng,Wangcai Zou,Zhenqiao Ma,Xiandi Yang,Qiang Zhao
As living standards improve, the demand for food freshness has gradually increased. Multifunctional packaging materials that monitor food freshness in real-time, delay spoilage, and are environmentally friendly have emerged as ideal solutions. This study synthesized an ammonia-sensitive copper-based metal-organic framework (Cu-MOF) and incorporated it into a matrix composed of chitosan (CS) and gelatin (Gel). The resulting film exhibits ammonia-sensitive color-changing properties, antibacterial activity, and excellent biodegradability. The effects of Cu-MOF incorporation on the structural, physical, and functional properties of the CS/Gel films were systematically evaluated. Results demonstrated that the Cu-MOF was uniformly distributed within the CS/Gel matrix, significantly enhancing the mechanical properties (tensile strength increased by 68.49%), oxygen/water vapor barrier properties, and UV-blocking capability of the films. Notably, the CS/Gel@Cu-MOF films exhibited excellent antibacterial performance, with sterilization rates of 94.2% against Escherichia coli and 99.6% against Staphylococcus aureus . Additionally, the films showed good biocompatibility, biodegradability, and a sensitive color response to ammonia. The films were successfully used to monitor shrimp freshness through color change, transitioning from light green to brown as spoilage occurred. These findings indicate that CS/Gel@Cu-MOF films have significant potential for real-time visual freshness monitoring in food packaging, contributing to reduced food safety risks and waste.
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COLLOIDS AND SURFACES B-BIOINTERFACES
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2012
·
IF 3.456
Rui Chen,Qi Chen,Da Huo,Yin Ding,Yong Hu,Xiqun Jiang
A novel chitosan–gold (CS–Au) hybrid hydrogel was developed from chitosan and chloroauric acid in aqueous solution. Its physiochemical characteristics, including UV absorption, structure, morphology, swelling properties were studied. The CS–Au hybrid hydrogel exhibited an excellent water-absorbing property and could be applied as a drug delivery system for anticancer drug: doxorubicin (DOX) due to its high equilibrium water swelling content. The drug loading and release experiments elicited an efficient drug loading content and sustained drug release pattern. Moreover, DOX released from hydrogel which itself had no cytotoxicity was biological active similar as the free DOX, but lower cytotoxicity due to its controllable release. All proved it an ideal local drug delivery system indicating a promising potential future in medical or pharmaceutical area.
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ELECTROANALYSIS
·
2024
·
IF 2.7
Jianrong Wang,Luhua Wang,Hongfang Zhao,Hongxia Li,Xiaohui Niu,Yi Wang,Kunjie Wang
Polysaccharide materials have wide applications in the field of chiral recognition. Herein, a new series of chiral materials based on chiral polysaccharide were synthesized for electrochemical enantioselective recognition of tryptophan (Trp) enantiomers. Chiral recognition was investigated via differential pulse voltammetry (DPV). Among poly (L-lactide) La/hydroxyapatite chitosan (PLLHC-X) series materials (PLLHC-0, PLLHC-1, PLLHC-3, PLLHC-7 PLLHC-9 and PLLHC-5), PLLHC-5 has the best recognition efficiency. And the results reveal that the PLLHC-5 displays a stronger interaction with L-Trp than to that of D-Trp. The synergetic effect of chiral recognition from chitosan and signal amplification from poly (L-lactide) (PLLA) offered an easy-handling and effective electrochemical approach for isomers discrimination to realize the chiral recognition of Trp enantiomers. The synergetic effect results in highly efficiency and thus opens up new directions in the field of chiral materials.
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LANGMUIR
·
2025
·
IF 3.9
Liang Zhao,Tuo Yang,Wentao Li,Xuewei Zhang,Qizhong Shi,Xin Feng,Yameng Wang,Xiafei Li,Wenbin Li
Extracorporeal circulation often causes mechanical damage to erythrocytes, which release hemoglobin into the plasma, resulting in postsurgical hazard, so lowering the free hemoglobin (f-Hb) level in the blood is important. In this study, based on the good biocompatibility of chitosan/κ-carrageenan and the adsorption effect of carbon nitride, a chitosan/κ-carrageenan/carbon nitride (CS/κ-Car/C3N4) hydrogel was prepared through the charge electrostatic interaction between polysaccharides. The incorporation of C3N4 enhanced both the adsorptive capacity and the stability of the hydrogel. Specifically, the CS/κ-Car/C3N4-0.4% hydrogel exhibited an adsorption amount of 185.79 mg/g for human hemoglobin, approximately twice that of the CS/κ-Car hydrogel. The CS/κ-Car/C3N4 hydrogel also showed a significantly lower breakage and degradation rate. In addition, the CS/κ-Car/C3N4 hydrogel did not induce hemolysis, complement activation, or coagulate when in contact with blood and showed good blood compatibility. Furthermore, in vivo studies in rabbits revealed that the CS/κ-Car/C3N4 hydrogel significantly reduced elevated f-Hb levels to near-normal concentrations postcirculation, without inducing any severe adverse effects on the subjects. This investigation has elucidated that the CS/κ-Car/C3N4 hydrogel possesses superior adsorptive efficacy and biocompatibility, effectively clearing f-Hb in vivo. Consequently, the findings of this study offer novel insights into the design paradigm for adsorbents intended for blood circulation applications.
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CARBOHYDRATE RESEARCH
·
2024
·
IF 2.4
Xuerong Luo,Lingyu Zhao,Imran Mahmood Khan,Lin Yue,Yin Zhang,Zhouping Wang
Curcumin (Cur) is a naturally hydrophobic polyphenol, and it has a wide range of physiological functions. But the practical application of Cur is constrained by its low water solubility and poor stability. To improve these deficiencies of Cur, a novel Cur derivative (CS-Cur) was prepared by grafting chitosan (CS) with Cur through a one-step reaction of a free radical-mediated redox system. A series of characterizations provided evidence that the grafting of CS with Cur was successful. The obtained CS-Cur showed lower crystallinity and thermal properties than CS and Cur. After grafting, the water solubility of CS-Cur was found to be 9.76 ± 2.45 g/L and greatly improved. Meanwhile, the CS-Cur showed good photothermal stability, antioxidant activity, and photodynamic antibacterial activity in an aqueous solution, and it had good in vitro biosafety. This provides an idea for the design and synthesis of novel highly water-soluble Cur derivatives and also improves the practical application of Cur in aqueous systems.
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RSC Advances
·
2024
·Vol. 14
·期 14
·9594-9601
·
IF 3.9
Yaotong Li,Chunru Zhao,Abdukayum Abdukader,Xiang Wu
Aqueous zinc ion batteries (AZIBs) have been widely investigated due to their characteristics of convenient operation and intrinsic safety. However, there are several issues to be addressed in AZIBs, such as slow diffusion kinetics of Zn2+, cathode material dissolution and the dendrite formation of zinc anodes. Thus, it is challenging to prepare a high-performance cathode material. In this work, we prepare NH4V4O10 flower-like structures by a facile hydrothermal route. The introduction of chitosan significantly enlarges the layer spacing of the (001) crystal plane. The assembled Zn//NVO-0.15C batteries deliver a specific capacity of 520.54 mA h g−1 at a current density of 0.2 A g−1. Furthermore, they maintain 91% of the retention rate at 5.0 A g−1 after 1000 times cycling. It demonstrates the excellent zinc ion storage behavior of ammonium vanadate electrode materials for AZIBs.
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