ACS Applied Materials & Interfaces
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2015
·
IF 6.723
Jianyong Sheng,Limei Han,Jing Qin,Ge Ru,Ruixiang Li,Lihong Wu,Dongqi Cui,Pei Yang,Yuwei He,Jianxin Wang
Although several strategies have been applied for oral insulin delivery to improve insulin bioavailability, little success has been achieved. To overcome multiple barriers to oral insulin absorption simultaneously, insulin-loaded N-trimethyl chitosan chloride (TMC)-coated polylactide-co-glycoside (PLGA) nanoparticles (Ins TMC-PLGA NPs) were formulated in our study. The Ins TMC-PLGA NPs were prepared using the double-emulsion solvent evaporation method and were characterized to determine their size (247.6 ± 7.2 nm), ζ-potential (45.2 ± 4.6 mV), insulin-loading capacity (7.8 ± 0.5%) and encapsulation efficiency (47.0 ± 2.9%). The stability and insulin release of the nanoparticles in enzyme-containing simulated gastrointestinal fluids suggested that the TMC-PLGA NPs could partially protect insulin from enzymatic degradation. Compared with unmodified PLGA NPs, the positively charged TMC-PLGA NPs could improve the mucus penetration of insulin in mucus-secreting HT29-MTX cells, the cellular uptake of insulin via clathrin- or adsorption-mediated endocytosis in Caco-2 cells and the permeation of insulin across a Caco-2 cell monolayer through tight junction opening. After oral administration in mice, the TMC-PLGA NPs moved more slowly through the gastrointestinal tract compared with unmodified PLGA NPs, indicating the mucoadhesive property of the nanoparticles after TMC coating. Additionally, in pharmacological studies in diabetic rats, orally administered Ins TMC-PLGA NPs produced a stronger hypoglycemic effect, with 2-fold higher relative pharmacological availability compared with unmodified NPs. In conclusion, oral insulin absorption is improved by TMC-PLGA NPs with the multiple absorption barriers overcome simultaneously. TMC-PLGA NPs may be a promising drug delivery system for oral administration of macromolecular therapeutics.
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高影响因子
JOURNAL OF POROUS MATERIALS
·
2020
·Vol. 27
·期 5
·1455-1466
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IF 2.183
Yuan Zhishuai,Cheng Yuchun,Ma Shoutao,Jiang Zhen,Zhou Yisi,Wang Yingjun,Zhang Wei,Suo Yanhua
A new method called Instant Exactness Synthesis (IES), which was applied to prepare SAPO-11 molecular sieve, was introduced innovatively. The metal–acid bifunctional Ni/SAPO-11-IES catalyst with a Ni content of 4% was prepared by the impregnation method. Ni/SAPO-11-H catalyst was prepared as a comparative sample through the traditional hydrothermal method. In addition, the growth mechanism was used to explain the excellent performance of catalyst prepared by IES method in detail. The structure of Ni/SAPO-11-IES was confirmed via XRD and TEM characterization. The pore structure of the molecular sieve was determined by nitrogen adsorption and desorption. 29 Si MAS NMR measurement was used to illustrate multiple silicon environment which supported the excellent acidity in NH 3 -TPD measurement. Furthermore, the favourable dispersibility of Ni species was proved by the mapping of the elements and EDS. Benefiting from the superior performance of materials, Ni/SAPO-11-IES catalyst exhibited a higher catalytic performance for n-heptane hydroisomerization with n-heptane conversion of 82% and isoheptane selectivity of 86%, respectively, compared with other catalysts in the same system. The study also provides new ideas for the preparation of molecular sieve materials.
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ChemSusChem
·
2024
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IF 7.5
Borong Liao,Junhao Gao,Pei Weng,Linya He,Yusheng Zhang,Qiuhua Liu,Zaichun Zhou
Graphical A semiconductor effect from 4d x 2 − y 2 (Pd) to a 2u (π) orbitals in Pd(II) porphyrin was discovered and a domino relationship from ring distortion, core deformation, band gap variation to photocatalytic activity was established and confirmed. In this work, four saddled Pd(II) porphyrins were developed as photocatalyst for N-dealkylation of triethyl Rhodamine (TER) under visible light, and their catalytic ability was found to be negatively related to the out-of-plane of their macrocycles. Two important relationships involving the metalloporphyrins as catalyst were revealed: (1) a photoexcitative semiconductor effect between the 4d x 2 − γ 2 (Pd) and a 2u (π) orbitals of Pd(II) porphyrin on the dealkylation. (2) a domino process from strap length, ring geometry, core deformation, d-π gap variation, to photocatalytic activity. Two revelations imply a unidirectional electron transfer route from axial ligand, to central metal, to porphyrin ring based on photoexcitation and guide the design and development of complex photocatalysts, and their revelation is attributed to the acquisition of a series of Pd(II) porphyrins with continuous ring distortion. The findings help to understand the photocatalytic single electron transfer (SET)-first mechanism based on metallic complex.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2026
·
IF 9.6
Min Wang,Yi Yang,Yang Zhang,Junxuan Zhang,Guicheng Liu,Woochul Yang,Fanghua Ning,Jinli Qiao
The direct integration of solar energy into zinc-air batteries (ZABs) provides a promising strategy for developing sustainable and high-performance energy storage systems. However, designing light-enhanced ZABs with efficient solar-energy utilization remains a significant scientific challenge. To address this challenge, a nitrogen-doped carbon/graphitic carbon nitride (N-C/g-C 3 N 4 ) composite photoelectrocatalyst was fabricated through mechanical ball-milling. Mechanical ball-milling enabled intimate interfacial coupling between N C and g-C 3 N 4 , thereby inducing interfacial electronic redistribution and facilitating charge transfer. Photoelectrochemical characterization, together with VB-XPS analysis, suggests that the N-C/g-C 3 N 4 interface promotes photogenerated electron transfer from g-C 3 N 4 to the conductive N C network while improving the utilization of photogenerated carriers. When used as the air cathode for ZABs, the composite exhibited strong bifunctional catalytic activity under illumination. Specifically, it exhibited an oxygen reduction reaction (ORR) half-wave potential (E 1/2 ) of 0.90 V and an oxygen evolution reaction (OER) overpotential of 501 mV. As a result, the assembled zinc-air battery (ZAB) achieved an open-circuit voltage (OCV) of 1.50 V, a peak power density of 572.9 mW cm −2 , a specific capacity of 720 mAh g −1 , and stable cycling for over 700 h. These results demonstrate the potential of interface-engineered dual‑carbon-based photoelectrocatalysts for high-efficiency solar-assisted metal-air batteries. Compared with N-C-based zinc-air battery (ZAB) and commercial Pt/C-IrO 2 -based ZAB, the light-enhanced N-C/g-C 3 N 4 -based ZAB exhibit improved photogenerated carrier utilization and facilitated interfacial charge transfer under illumination. These advantages lead to a significant performance enhancement, including an open-circuit voltage of 1.50 V, a peak power density of 572.9 mW cm −2 and ultra-stable charge-discharge cycling for over 700 h. Download: Download high-res image (97KB) Download: Download full-size image
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Chemistry-An Asian Journal
·
2026
·Vol. 21
·期 14
·e70889
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IF 3.2
Jiajia Wang,Fangting Xie,Heng Lin,Ruiqing Luo,Zhiqi Ma,Duming Wei,Didan Dong,Jingru Liang,Ruiqing Zhang,Wenyu Liang,Yumei Qin,Qingmin Wei,Guangfeng Zeng
Lithium–sulfur (Li–S) batteries, despite their high theoretical capacity (1675 mAh g −1 ) and low-cost sulfur, suffer from poor cycling stability, and rate performance. This is mainly due to sluggish redox kinetics at the sulfur cathode-particularly during the Li 2 S 2 to Li 2 S conversion. In addition, uneven lithium-ion distribution and random diffusion lead to unsafe issues due to unstable lithium deposition and dendrite growth. In this study, an interlayer composed of N, S dual-doped carbon is designed to reinforcing sulfur redox electrochemistry and promoting uniform Li deposition. The NSC interlayer enhances the electrochemical performances via the formation of N … Li and S B 0 active sites, which accelerate polysulfides conversion and regulate Li deposition. As a result, the Li–S batteries with the NSC interlayer achieve an ultrahigh discharge specific capacity of 1215 mAh g −1 at 0.2C and 617 mAh g −1 at a high current of 5C. In addition, the NSC interlayer enables uniform Li deposition for over 1000 h. The work provides a facile method for designing functional interlayers and opens a new avenue for realizing Li–S batteries with high energy efficiency.
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ADVANCED MATERIALS
·
2026
·
IF 29.1
Jiage Yu,Wei Liu,Lu Bai,Benqiang Tian,Qingyi Zhu,Qianxi Yang,Linlin Zhou,Haoyang Wu,Yuan Wang,Boyuan Li,Xiangrong Jin,Yun Kuang,Jiazhan Li,Xiaoming Sun
CO 2 electroreduction typically requires large overpotentials to sustain high reaction rates, which at current densities approaching 1 A cm −2 inevitably intensify competition from the hydrogen evolution reaction (HER), making it difficult to simultaneously sustain high product selectivity (>95%). In this study, hollow Ni─NC (H-Ni-NC) was synthesized using nanoscale silica sphere templates and atomic Zn as a sacrificial pore-former within the carbon shell. The optimized H-Ni-NC achieves a current density of −1.0 A cm −2 with over 95% CO Faradaic efficiency in a flow cell. The high performance was attributed to the hollow sphere architecture enriched with gas-permeable through-pores. Notably, the Zn dosage selectively modulates the shell through-porosity, without altering hollow sphere macrostructure or the active-site structure, thereby enabling a systematic investigation of porosity effects. Finite-element simulations provide a qualitative framework suggesting a trade-off between reactant transport and active surface area with increasing porosity in hollow spherical catalysts. This work underscores that engineering of the nanoscale mass-transport environment surrounding active sites plays a critical role in designing high-efficiency electrocatalysts.
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JOURNAL OF MATERIALS SCIENCE
·
2026
·
IF 4.4
Li Xiangqian,Chen Zhangying,Mao Zilu,Wu Dechao,Li Jiajun,Chong Huiying,Zeng Yelin,Wang Yonghong,Peng Kuan,Wu Yaohui
As a widely used antibiotic, tetracycline (TC) is a prevalent aquatic contaminant. Its environmental persistence presents substantial ecological hazards and potential health risks. This research utilized an in situ hydrothermal technique to modify Bi 2 MoO 6 (BMO) with N-doped biochar (NBC), yielding a highly efficient photocatalyst. The photocatalytic efficacy of the manufactured materials in degrading TC under visible light was evaluated by characterizing its morphology and optical properties. Experimental findings demonstrated that the ideal mass ratio of NBC in the NBC/BMO composites was 20 wt%. In 50 mL of 40 mg L −1 TC solution, 0.2 g of catalyst achieved an adsorption-photocatalytic efficiency of 86.1% after 60 min of dark adsorption followed by 120 min of photocatalytic treatment, which was 2.26 and 1.39 times greater than BMO and 20% BC/BMO, respectively. The adsorption kinetics conformed to a pseudo-second-order model, with a maximum adsorption capacity of 19.45 mg g −1 , signifying that chemical adsorption was the predominant process. The enhanced adsorption performance was attributed to N-doped effectively promoting the separation and migration of photogenerated electron–hole pairs, significantly reducing carrier recombination rates. Concurrently, the composites exhibited a pronounced visible light absorption red shift, regulating optical bandgap and markedly improving visible light utilization. Superoxide radicals (•O 2 − ) and holes (h + ) were key active species in the photocatalytic degradation of TC. After five regeneration cycles, the composites maintained high removal efficiency for TC. This research not only provides a simple preparation method for N-doped BC photocatalysts but also offers an effective and low-cost strategy for utilizing biomass resources to remediate antibiotic-contaminated water bodies. Graphical
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JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2026
·
IF 4.4
Supeng Gao,Binbin Wang,Yujie Cheng,Mengyan Feng,Yue Han,Tao Li,Shuguang Cao,Yao Li,Lingwei Xue
An n-type dimeric organic molecule, B2, is employed as an interfacial modifier to regulate the contact property between the perovskite layer and PCBM ETL in inverted PSCs. • B2 interlayer passivates defects in the perovskite layer and optimizes the energy level alignment at the interface. • A prominent PCE of 20.20% is delivered by PSCs with B2 as the interlayer, alongside minimal hysteresis. • The unencapsulated devices retain more than 80% of initial PCE after 1000 h in ambient humid air. Interface engineering at the perovskite/electron transport layer (ETL) junction has been demonstrated as an effective strategy for achieving high-quality interfacial contact in perovskite solar cells (PSCs). In this work, an n-type dimeric organic molecule, B2, is employed as an interfacial modifier to regulate the contact property between the perovskite layer and PCBM ETL. Experimental results reveal that the B2 interlayer passivates defects in the perovskite layer through coordination with undercoordinated Pb 2+ ions, thereby suppressing trap-assisted non-radiative recombination. Furthermore, the B2 modification optimizes the Energy level alignment at the interface, promoting efficient charge carrier transport. As a result of these synergistic effects, the interface-engineered PSCs achieve a power conversion efficiency of 20.20% and maintain over 80% of their initial efficiency after 1056 h of aging tests. This study provides an effective interfacial regulation approach for developing highly efficient and stable PSCs. Download: Download high-res image (136KB) Download: Download full-size image
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2026
·
IF 5.4
Zhuanzhuan Shi,Zuqiang Ma,Liang Liu,Xiaoshuai Wu,Lishan Long,Jiahao Li,Zihan Wang
An electrochemical CAP sensor is constructed by CoNi/N-CNTs synthesized using nickel foam and melamine. • CoNi/N-CNTs features abundant active centers, fast electron transfer and synergistic catalytic efficiency for CAP reduction. • The sensor attains a low detection limit of 67 nM and a wide linear range for CAP detection. • Its Its practical application potential is validated by excellent stability and repeatability. The abuse of chloramphenicol (CAP) can trigger environmental and health issues, making it crucial to establish rapid and sensitive detection methods. Electrochemical sensors have garnered significant attention due to their advantages of simple operation and high sensitivity, with the performance of these sensors hinging on electrode sensing materials. In this study, using nickel foam and melamine as substrates and through appropriate cobalt doping, a cobalt-nickel nitrogen-doped carbon nanotube (CoNi/N-CNTs) composite material was successfully synthesized. Subsequently, a high-performance CAP electrochemical sensor was constructed based on this material. In this sensor, the unique carbon nanotube structure of CoNi/N-CNTs provides abundant adsorption sites for CAP molecules. Meanwhile, its excellent electrical conductivity ensures rapid electron transfer between the electrode material and CAP molecules. Moreover, the uniform dispersion of Co and Ni forms stable electrocatalytic active centers, synergistically facilitating the reduction reaction of CAP. This sensor exhibits two linear ranges of 0.2–12 μM and 12–300 μM, a low detection limit of 67 nM, and a high sensitivity of 35.38 μA·μM·cm −2 in the low concentration range (0.2–12 μM). It also demonstrates outstanding anti-interference ability. Additionally, the sensor shows strong stability, maintaining 99.1% of its initial performance after 14 days and achieving a repeatability of 98.7% in eight independent experiments. This study offers an efficient and reliable method for detecting CAP in the environment, with broad application prospects. Download: Download high-res image (190KB) Download: Download full-size image
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MOLECULES
·
2026
·Vol. 31
·期 12
·2014
·
IF 5.1
Bo Yu,Suchang Zou,Tianle Wang,Feng Guo,Weilong Shi,Zhimin Ao
As the growing presence of antibiotic residues in environmental water bodies poses an increasing risk to ecological safety and human health, developing simple and efficient methods for the targeted detection of antibiotics is of particular importance. In this study, we propose a simple method for the one-step hydrothermal synthesis of N, S-co-doped carbon dots (N, S-CDs) using disulfide bonds from discarded badminton shuttlecocks. We investigated the effects of different synthesis temperatures on its performance and confirmed the method’s excellent performance in detecting tetracycline (TC) concentrations, with results demonstrating that varying synthesis temperatures affect the degree and distribution of carbonization, thereby influencing fluorescence intensity. Consequently, employing N, S-CDs-180, which exhibits optimal photoluminescence properties, as the sensing probe for the detection of TC solutions at varying concentrations yielded an excellent linear equation for fluorescence quenching and the detection limit is 1.963 mg/L. Additionally, the fluorescence stability of N,S-CDs-180 was investigated in laboratory water, tap water, seawater, lake water, and industrial wastewater, all of which demonstrated exceptional environmental adaptability. Furthermore, a systematic investigation into the target selectivity of N, S-CDs-180 toward various antibiotics revealed that this material exhibits a sensitive quenching response specifically to tetracycline-class antibiotics while showing no quenching effect on non-tetracycline antibiotics, collectively indicating that the as-prepared N, S-CDs can serve as potential fluorescent probes for the highly selective detection of tetracycline-class antibiotics in complex aqueous systems.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2026
·
IF 9.1
Qingping Xin,Yufei Wang,Wei Huang,Shuo Li,Xingwei Wang,Jiaxin Wu,Dengdi Wu,Mengke Wang,Huiguo Wang,Ningning Gao,Xiaoli Ding,Yuzhong Zhang
Two-dimensional (2D) lamellar membranes with sub-nanometer channels hold promise for precise gas separation, but tuning interlayer spacing at the sub-angstrom scale while synergizing solution-diffusion and molecular sieving remains challenging. Here we report the confinement of an ionic liquid (IL), 1-butyl-3-methylimidazolium tetrafluoroborate ([BMIM][BF 4 ]), within the galleries of few-layer Al@Ti 3 C 2 T x nanosheets to create ionic liquid-confined lamellar MXene membranes (Al@Ti 3 C 2 T x -ILLMMs). The residual Al 3+ species in the nanosheets stabilize the interlayer architecture through electrostatic interactions, while the abundant surface terminations (-F, -OH) render the nanosheets negatively charged, promoting uniform IL distribution. By precisely controlling the IL loading via an equilibration–spin-coating approach, the interlayer spacing is continuously tunable from 0.309 to 0.375 nm. The optimal channel height of 0.342 nm lies within the gap between the kinetic diameters of CO 2 (0.33 nm) and N 2 (0.36 nm), closer to that of CO 2 . This precision engineering shifts the gas transport mechanism from Knudsen diffusion to a coupled solution-diffusion and size-sieving regime. The resulting membrane achieves a CO 2 permeance of 150 GPU and a CO 2 /N 2 selectivity of 128.5, representing 4.5-fold and 109-fold improvements over the pristine MXene membrane and offering a favorable balance compared to reported IL-supported membranes. The demonstrated quantitative loading-spacing correlation provides a designable platform for sub-angstrom channel engineering in 2D material membranes.
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APPLIED CATALYSIS B-ENVIRONMENTAL
·
2026
·
IF 19.7
Wenqing Wang,Fan Wu,Hao Li,Jianming Pan
A photocatalytic self-propelled nanomotor adsorbent was developed for Pd(II) recovery. • Self-propulsion overcomes diffusion-limited adsorption kinetics. • EPR reveals the ROS-mediated mechanism of long-term propulsion. • Selective Pd(II) recovery is achieved in complex acidic wastewater. The recovery of palladium (Pd) from complex acidic industrial wastewater is severely restricted by sluggish interfacial mass transfer and inherent diffusion-limited adsorption kinetics. To address this long-standing bottleneck, asymmetric N/Se-codoped resorcinol-formaldehyde nanomotors (Se-RF@NMs) were rationally fabricated via an emulsion-confined anisotropic growth strategy for photocatalytic self-propulsion-boosted Pd(II) recovey. Under light irradiation, the photoresponsive resin framework enables continuous in-situ H 2 O 2 generation. Meanwhile, the adsorption-induced in-situ reduction of Pd(II) further accelerates catalytic H 2 O 2 decomposition to generate oxygen microbubbles, endowing nanomotors with sustainable autonomous motion and dynamically promoting interfacial ion transport. EPR characterization confirms that photogenerated holes and reactive oxygen species sustain the cyclic H 2 O 2 generation-decomposition system, effectively stabilizing the self-propulsion behavior of Se-RF@NMs. Benefiting from the synergistic coupling of photocatalytic self-propulsion and N/Se-based selective coordination adsorption, the optimized Se-RF@NMs achieve a superior Pd(II) adsorption capacity of 196.75 mg g −1 , as well as excellent selectivity in multi-metal competitive systems and practical industrial wastewater matrices. This work elucidates a photocatalysis-driven active mass transfer enhancement mechanism, establishing a feasible paradigm to break the intrinsic diffusion limitation of conventional adsorption. It provides new insights into the rational design of intelligent self-propelled catalytic adsorbents for high-efficiency precious metal recovery in complex and harsh water environments. Download: Download high-res image (152KB) Download: Download full-size image
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危险品化学品经营许可证（带存储）