ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2023
·Vol. 30
·期 41
·94112-94125
·
IF 5.8
Zhang Mingyuan,Li Yueyao,Zhou Xiaoying,Wang Liping,Xie Yuke,Hou Chentao
In recent years, wastewater treatment to remove tetracycline hydrochloride (TCH) has received much attention in water treatment problems. ZIF-67/C 3 N 4 composite adsorbent, a nanosheet structured material stacked with MOFs, was prepared by in situ growth method, which has high adsorption activity for tetracycline hydrochloride in wastewater. Comparing the effect of monomeric and composite adsorbents, Z 6 C 2 had the best adsorption effect (206 mg·g −1 ), which was 77.6% higher than that of ZIF-67 (116 mg·g −1 ) and 10.8 times higher than that of C 3 N 4 (19 mg·g −1 ). The structure of ZIF-67 stacked on C 3 N 4 nanosheets has an excellent specific surface area and number of active sites, as well as π-π interactions, electrostatic interactions, and hydrogen bonding interactions between the adsorbent and TCH, which combine to enhance the adsorption performance. The adsorption process is accompanied by a combination of chemisorption, mass transport, and internal diffusion rate-limiting. It was shown that the adsorption process is favorable for monolayer adsorption as well as a heat absorption reaction that proceeds spontaneously. The adsorbent exhibits good stability and adsorption capacity, which may be suitable for efficient and low-cost water purification.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Cell Discovery
·
2023
·Vol. 9
·期 1
·1-18
·
IF 33.5
Gao Xiu Kui,Sheng Zu Kang,Lu Ye Hong,Sun Yu Ting,Rao Xi Sheng,Shi Lin Jing,Cong Xiao Xia,Chen Xiao,Wu Hao Bo,Huang Man,Zheng Qiang,Guo Jian-sheng,Jiang Liang Jun,Zheng Li Ling,Zhou Yi Ting
The scaffold protein IRS-1 is an essential node in insulin/IGF signaling. It has long been recognized that the stability of IRS-1 is dependent on its endomembrane targeting. However, how IRS-1 targets the intracellular membrane, and what type of intracellular membrane is actually targeted, remains poorly understood. Here, we found that the phase separation-mediated IRS-1 puncta attached to endoplasmic reticulum (ER). VAPB, an ER-anchored protein that mediates tethers between ER and membranes of other organelles, was identified as a direct interacting partner of IRS-1. VAPB mainly binds active IRS-1 because IGF-1 enhanced the VAPB-IRS-1 association and replacing of the nine tyrosine residues of YXXM motifs disrupted the VAPB-IRS-1 association. We further delineated that the Y745 and Y746 residues in the FFAT-like motif of IRS-1 mediated the association with VAPB. Notably, VAPB targeted IRS-1 to the ER and subsequently maintained its stability. Consistently, ablation of VAPB in mice led to downregulation of IRS-1, suppression of insulin signaling, and glucose intolerance. The amyotrophic lateral sclerosis (ALS)-derived VAPB P56S mutant also impaired IRS-1 stability by interfering with the ER-tethering of IRS-1. Our findings thus revealed a previously unappreciated condensate-membrane contact (CMC), by which VAPB stabilizes the membraneless IRS-1 signalosome through targeting it to ER membrane.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Coatings Technology and Research
·
2023
·Vol. 20
·期 6
·2069-2080
·
IF 2.3
Wang Rui,Yi Hongling
Non-covalent modification of graphene is prepared by sodium carboxymethyl cellulose via ball milling. Adsorption and thermogravimetric analyzer (TG) indicate interaction of graphene with sodium carboxymethyl cellulose. Particle size and zeta potential results show sodium carboxymethyl cellulose with high DS play more role in assisting stabilization of graphene dispersion. The adsorption of sodium carboxymethyl cellulose onto graphene is inhibited under acidic conditions and the dispersion stability deteriorates sharply. Under neutral and alkaline conditions, the dispersions maintain stable. Embedding a small percentage of well-dispersed graphene nanosheets (CGr1.5%) in waterborne epoxy coating has remarkably improved anticorrosion performance, which is attributed to the synergistic effects of barrier properties of well-dispersed graphene nanosheets and CMC in the epoxy matrix. Open circuit potential (OCP), Tafel and electrochemical impedance spectroscopy (EIS) analysis confirmed that the corrosion rate exhibited by composite coatings with 1.5 wt% graphene is lower than that of neat epoxy coating.
✓ 已验证
产品关联
DOI
高影响因子
Nano Research
·
2023
·
IF 9.9
Yue Meng,He Xun,Sun Shengjun,Sun Yuntong,Hamdy Mohamed S.,Benaissa Mhamed,Salih Alsamani A. M.,Liu Jun,Sun Xuping
Developing efficient and durable oxygen evolution reaction (OER) catalysts holds great promise for green hydrogen production via seawater electrolysis, but remains a challenge. Herein, we report a Co-doped Ni 3 S 2 nanosheet array on Ni foam (Co-Ni 3 S 2 /NF) as a high-efficiency OER electrocatalyst for seawater. In alkaline conditions, Co-Ni 3 S 2 /NF requires an overpotential of only 368 mV to drive 100 mA·cm −2 , superior to Ni 3 S 2 /NF (385 mV). Besides, it exhibits at least 50-h continuous electrolysis.
✓ 已验证
产品关联
DOI
高影响因子
CELL RESEARCH
·
2023
·
IF 44.1
Ai Yuan-li,Wang Wei-jia,Liu Fan-jian,Fang Wei,Chen Hang-zi,Wu Liu-zheng,Hong Xuehui,Zhu Yuekun,Zhang Ci-xiong,Liu Long-yu,Hong Wen-bin,Zhou Bo,Chen Qi-tao,Wu Qiao
Pyroptosis is a type of regulated cell death executed by gasdermin family members. However, how gasdermin-mediated pyroptosis is negatively regulated remains unclear. Here, we demonstrate that mannose, a hexose, inhibits GSDME-mediated pyroptosis by activating AMP-activated protein kinase (AMPK). Mechanistically, mannose metabolism in the hexosamine biosynthetic pathway increases levels of the metabolite N -acetylglucosamine-6-phosphate (GlcNAc-6P), which binds AMPK to facilitate AMPK phosphorylation by LKB1. Activated AMPK then phosphorylates GSDME at Thr6, which leads to blockade of caspase-3-induced GSDME cleavage, thereby repressing pyroptosis. The regulatory role of AMPK-mediated GSDME phosphorylation was further confirmed in AMPK knockout and GSDME T6E or GSDME T6A knock-in mice. In mouse primary cancer models, mannose administration suppressed pyroptosis in small intestine and kidney to alleviate cisplatin- or oxaliplatin-induced tissue toxicity without impairing antitumor effects. The protective effect of mannose was also verified in a small group of patients with gastrointestinal cancer who received normal chemotherapy. Our study reveals a novel mechanism whereby mannose antagonizes GSDME-mediated pyroptosis through GlcNAc-6P-mediated activation of AMPK, and suggests the utility of mannose supplementation in alleviating chemotherapy-induced side effects in clinic applications.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2023
·Vol. 14
·期 1
·1-11
·
IF 16.6
Liang Zhaoheng,Tian Fei,Yang Gongzheng,Wang Chengxin
Aqueous sodium-ion batteries (AIBs) are promising candidates for large-scale energy storage due to their safe operational properties and low cost. However, AIBs have low specific energy (i.e., <80 Wh kg −1 ) and limited lifespans (e.g., hundreds of cycles). Mn-Fe Prussian blue analogues are considered ideal positive electrode materials for AIBs, but they show rapid capacity decay due to Jahn-Teller distortions. To circumvent these issues, here, we propose a cation-trapping method that involves the introduction of sodium ferrocyanide (Na 4 Fe(CN) 6 ) as a supporting salt in a highly concentrated NaClO 4 -based aqueous electrolyte solution to fill the surface Mn vacancies formed in Fe-substituted Prussian blue Na 1.58 Fe 0.07 Mn 0.97 Fe(CN) 6 · 2.65H 2 O (NaFeMnF) positive electrode materials during cycling. When the engineered aqueous electrolyte solution and the NaFeMnF-based positive electrode are tested in combination with a 3, 4, 9, 10-perylenetetracarboxylic diimide-based negative electrode in a coin cell configuration, a specific energy of 94 Wh kg –1 at 0.5 A g −1 (specific energy based on the active material mass of both electrodes) and a specific discharge capacity retention of 73.4% after 15000 cycles at 2 A g −1 are achieved.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Carbon Letters
·
2023
·Vol. 33
·期 7
·2129-2139
·
IF 4.5
Tang Shanshan,Liang Axin,Liu Miao,Wang Wei,Zhang Fulai,Luo Aiqin
A glassy carbon electrode modified with a composite consisting of electrodeposited chitosan and carboxylated multi-walled carbon nanotubes (e-CS/MWCNTs/GCE) was used as a working electrode for simultaneous determination of dopamine (DA), serotonin (5-HT) and melatonin (MT), which were related to circadian rhythms. The electrochemical characterizations of the working electrode were carried out via electrochemical impedance spectroscopy and chronocoulometry. It was found that electrochemical modification method, that was cyclic voltammetry, may can cause continuous CS polymerization on MWCNTs surface to form a dense membrane with more active sites on the electrode, and the electrochemically active surface area of e-CS/MWCNTs/GCE obtained was about 7 times that of GCE. The electrochemical behaviour of DA, 5-HT and MT on working electrode were carried out via differential pulse voltammetry and cyclic voltammetry. The results showed that e-CS/MWCNTs/GCE solved the problem that the bare electrode could not detect three substances simultaneously, and can catalyze oxidation potential difference as low as 0.17 V of two substances reaction at the same time, indicating very good electrocatalytic activity. By optimizing the detection conditions, the sensor showed a good linear response to DA, 5-HT and MT in the range of 20-1000 μmol/L, 9-1000 μmol/L and 20-1000 μmol/L, and the detection limits were 12 μmol/L, 10 μmol/L and 22 μmol/L (S/N = 3), respectively. In addition, the proposed sensor was successfully applied to the simultaneous detection of DA, 5-HT and MT in human saliva samples.
✓ 已验证
产品关联
DOI
高影响因子
Microsystems & Nanoengineering
·
2022
·Vol. 8
·期 1
·1-10
·
IF 8.006
Sun Hao,Fang Xudong,Fang Ziyan,Zhao Libo,Tian Bian,Verma Prateek,Maeda Ryutaro,Jiang Zhuangde
Flexible strain sensors are promising candidates for intelligent wearable devices. Among previous studies, although crack-based sensors have attracted a lot of attention due to their ultrahigh sensitivity, large strain usually causes fractures in the conductive paths. Because of the unstable crack structure, the tradeoff between sensitivity and workable strain range is still a challenge. As carbon nanotubes (CNTs) and silver nanowires (AgNWs) can form a strong interface with the thermoplastic substrate and strengthen the conductive network by capillary force during water evaporation, CNTs and AgNWs were deposited on electrospun TPU fiber mats via vacuum-assisted filtration in this work. The prestretching treatment constructed a microcrack structure that endowed the sensor with the combined characteristics of a wide working range (0~171% strain), ultrahigh sensitivity (a gauge factor of 691 within 0~102% strain, ~2 × 10 4 within 102~135% strain, and > 11 × 10 4 within 135~171% strain), a fast response time (~65 ms), small hysteresis, and superior durability ( > 2000 cycles). Subsequently, the sensing mechanism of the sensor was studied. Distributed microcrack propagation based on the “island-bridge” structure was explained in detail, and its influence on the strain-sensing behavior of the sensor was analyzed. Finally, the sensor was assembled to monitor various vibration signals and human motions, demonstrating its potential applications in the fields of electronic skin and human health monitoring.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Applied Nanoscience
·
2022
·Vol. 12
·期 12
·3995-4004
·
IF 3.869
Bao Li-hong,Wen Yu-xin,Ling Jia-wen,Guan Fang-lan,Nie Jin-mei,Zhang Mei
In this study, titanium dioxide (TiO 2 ) and graphene oxide (GO) were used to make a titanium dioxide/reduced graphene oxide (TG) composite under hydrothermal condition, and the TG composite was subsequently dye-sensitization (DTG). TEM, XRD, Raman, XPS, and UV–vis DRS spectroscopy were used to examine the structure and morphology of DTG, and the results revealed that the grafting rate of dye molecules on TG was approximately 20.4% and the band-gap value for TiO 2 , TG and DTG were 3.21, 3.03, 2.57 eV, respectively. The photocatalytic performances of DTG, TG, and TiO 2 were investigated under the illumination of a xenon lamp, and it was discovered that the final removal rates of MB by TiO 2 and TG were only 21.53% and 50.37%, but DTG can remove 97.67% of MB, the COD value of the effluent decreased by 88.24%. Furthermore, the elimination rate of MB maintained over 90% after 5 cycles of photocatalytic tests, indicating that DTG had good endurance.
✓ 已验证
产品关联
DOI
高影响因子
KOREAN JOURNAL OF CHEMICAL ENGINEERING
·
2022
·Vol. 39
·期 12
·3305-3314
·
IF 3.146
Liu Zhihao,Qiu Kui,Dong Yu,Jin Zhaobo,Liu Luwei,Wu Jirong
A non-aqueous phase (Sb/Fe/NMP) desulfurization system for the removal of hydrogen sulfide from natural gas was constructed by introducing SbCl 3 and FeCl 3 in a specific ratio into N-methylpyrrolidone (NMP). The desulfurizing agent and its sulfur product were characterized, and the absorption pattern of H 2 S by the system was investigated by static desulfurization experiments. The results indicate that the desulfurizer’s sulfur capacity can reach 16 g/L at room temperature and pressure, and that adding the optimum amount of water and appropriate temperature increase can assist to increase desulfurization efficiency. The system maintained a sulfur capacity level of more than 90% of the initial sulfur capacity after five consecutive desulfurization-regeneration cycles. XRD and XPS spectrogram revealed that the regenerated solid product was high purity sulfur. Sb 3+ is a key component to ensure the effective absorption of H 2 S. The presence of a moderate amount of Fe 3+ can oxidize and absorb small amounts of H 2 S and promote the oxidative regeneration of the system. In addition, we combined the obtained experimental data with density flooding theory (DFT) theoretical calculations to show that the effective coordination of Sb(III) with HS − in the NMP environment is the main reason for the effective absorption of H 2 S by the desulfurizer. NMP is not involved in the coordination absorption process of hydrogen sulfide.
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2022
·Vol. 13
·期 1
·1-9
·
IF 17.694
Zhang Xiaoran,Zhu Xiaorong,Bo Shuowen,Chen Chen,Qiu Mengyi,Wei Xiaoxiao,He Nihan,Xie Chao,Chen Wei,Zheng Jianyun,Chen Pinsong,Jiang San Ping,Li Yafei,Liu Qinghua,Wang Shuangyin
Electrocatalytic urea synthesis emerged as the promising alternative of Haber–Bosch process and industrial urea synthetic protocol. Here, we report that a diatomic catalyst with bonded Fe–Ni pairs can significantly improve the efficiency of electrochemical urea synthesis. Compared with isolated diatomic and single-atom catalysts, the bonded Fe–Ni pairs act as the efficient sites for coordinated adsorption and activation of multiple reactants, enhancing the crucial C–N coupling thermodynamically and kinetically. The performance for urea synthesis up to an order of magnitude higher than those of single-atom and isolated diatomic electrocatalysts, a high urea yield rate of 20.2 mmol h −1 g −1 with corresponding Faradaic efficiency of 17.8% has been successfully achieved. A total Faradaic efficiency of about 100% for the formation of value-added urea, CO, and NH 3 was realized. This work presents an insight into synergistic catalysis towards sustainable urea synthesis via identifying and tailoring the atomic site configurations.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF POLYMER RESEARCH
·
2022
·Vol. 29
·期 10
·1-11
·
IF 3.061
Xie Zhiyuan,Wang Dong,Yu Zhanyu,Zheng Wen,Liu Bo,Zhang Aibo
Poly(styrene-sodium p-styrene sulfonate) microspheres with porous morphology were prepared by dispersion polymerization and seed swelling selecting two monomers of sodium p-styrene sulfonate and styrene, which are denoted as P(St-NaSS). The method is simple and easy to effectively control the pore structure microspheres. The SEM results showed that the surface morphology of P(St-NaSS) microspheres is in porous, and the diameter of pores is about 0.5 μm. In this paper, the influence of swelling time on the pore size was investigated. The SEM results indicated that the longer the swelling time, the larger the pore size of microspheres. The absorbing hybrids of swelled multi-porous P(St-NaSS) @MWCNTs and non-swelled P(St-NaSS)@MWCNTs with three-dimensional conductive network were assembled by π bond stacking effect, and study the strength of its absorption of electromagnetic waves. Compared with P(St-NaSS)@MWCNTs hybrids, the multi-porous P(St-NaSS) hybrids exhibited better absorbing performance, the reflection loss is -35.24 dB at 7.15 GHz at 2 mm thick, while the reflection loss of P(St-NaSS)@MWCNTs is -24.63 dB. The experimental results show that the existence of porous in wave-transparent microspheres played an important role in improving the impedance matching, increasing the path of multiple reflection scattering, which is beneficial to improve the absorption of MWCNTs.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）