INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2024
·
IF 8.1
Ligang Ma,Chao Lin,Wenjun Jiang,Le Xu,Yujie Shao,Tianyu Zhu,Ting Zhao,Xiaoqian Ai,Xiaoshan Wu
In the face of energy scarcity and environmental degradation, photocatalysis emerges as a green and highly efficient method to convert solar energy into a renewable energy source . In this study, CdS nanoparticles were successfully grown in situ along the edges of ZnIn 2 S 4 nanosheets using ultrasound during the synthesis process and the second phase precipitation of In(OH) 3 appeared in the process of preparation. Optimal Cd and S ratios resulted in ZnIn 2 S 4 @In(OH) 3 @CdS heterojunction exhibiting remarkable photocatalytic H 2 production performance compared to standalone ZnIn 2 S 4 and CdS. The internal heterojunction interface within the composite naturally generates an electric field, enhancing carrier separation and facilitating their transport. Additionally, the inclusion of In(OH) 3 further expedites carrier extraction. Ultimately, the mechanism behind the photocatalytic H 2 production was elucidated using the Z-scheme mechanism. This work introduced a novel approach to fabricating multifunctional photocatalysts , presenting a fresh perspective in their design and preparation.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2024
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IF 5.7
Arong Wang,Cheng Guan,Tieqi Wang,Guangqing Mu,Yanfeng Tuo
Our previous studies have shown that Lactiplantibacillus plantarum DPUL-S164-derived indole-3-lactic acid (ILA) ameliorates intestinal epithelial cell barrier injury by activating aryl hydrocarbon receptor (AhR) and nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathways and promoting tight junction protein expression. This study further explored the crucial substances of L. plantarum DPUL-S164 in alleviating intestinal barrier damage in mice through a dextran sodium sulfate-induced ulcerative colitis mouse model. Compared to dead L. plantarum DPUL-S164 (D-S164), live L. plantarum DPUL-S164 (S164) and its tryptophan metabolite, ILA, showed an effective ameliorating effect on the intestinal barrier injury of mice treated by antibiotic cocktail and sodium dextran sulfate, suggesting that the crucial substances of L. plantarum DPUL-S164 ameliorating intestinal barrier injury are its extracellular metabolites. Furthermore, S164 and its tryptophan metabolite, ILA, ameliorate intestinal barrier injury and suppress intestinal inflammation by activating the AhR–Nrf2 pathway and inhibiting the nuclear factor kappa-B (NF-κB) pathway. These results suggest that L. plantarum DPUL-S164 ameliorates intestinal epithelial barrier damage in mice, primarily by producing ILA as a ligand to activate the AhR pathway.
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ACS Applied Materials & Interfaces
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2025
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IF 8.2
Ke-Juan Meng,Kunyu Xiong,Iftikhar Hussain,Momang Tian,Xinwen Ma,Yuxiang Li,Qi-Long Yan,Kaili Zhang
Advanced energetic composites possess promising properties and wide-ranging applications in explosives and propellants. Nonetheless, most metal-based energetic composites present significant challenges due to surface oxidation and low-pressure output. This study introduces a facile in situ method to develop energetic composites Cutztr@AP through the intermolecular assembly of nitrogen-rich energetic coordination polymers and high-energy oxidant ammonium perchlorate (AP). Morphological analysis reveals the unique structure of Cutztr@AP, where Cutztr is distributed throughout the interior and surface of the AP particles. The nonisothermal thermodynamic analysis reveals a heat release of 2378.2 J g–1 for Cutztr@AP2, outperforming the Cutztr/AP2 achieved through ultrasonic mixing (2000 J g–1). Notably, Cutztr@AP2 exhibits promising combustion and pressure output performances, including a significantly shorter duration, a larger flame area, and higher pressure values. This novel and facile preparation technique and microstructure design approach holds significant promise for high-performance propellants, gas generators, and other related applications.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
·
IF 7.7
Mingmei Xiao,Jiuhua Zhang,Jiajin Wu,Ning Yuan,Tao Liu,Chunzhi Tang,Nenggui Xu,Qingxin Li,Jinchuan Wu,Shijie Li,Zhuoyue Song
3-Acetylaconitine (AAC) is a commercially analgesic drug for arthritis, however, due to its narrow safety range, its clinical application is limited. The objective of the study was to investigate the combined effect of Cucumaria frondosa polysaccharide (CFP) and AAC in microneedles on knee osteoarthritis (KOA). The characterization of microneedles was conducted and a rat model of monosodium iodoacetate (MIA)-induced KOA was established to evaluate the anti-inflammatory and analgesic activity in this study. The inhibitory effects on cartilage degradation and synovial inflammation were determined by morphological observation of the knee joint, pathological and imaging results. The von Frey pain threshold and hind limb weight bearing test were used to evaluate the effect of microneedles on pain relief. The results showed that microneedles had the mechanical strength to penetrate the skin and dissolved well in the skin for drug delivery within 30 min after patch administration. Furthermore, AAC-MN and CFP-AAC-MN both played roles in relieving pain, reducing cartilage degeneration and inhibiting synovial inflammation in KOA. In summary, CFP combined with AAC loading into microneedles exhibited higher skin penetration and more advantages in inhibiting cartilage damage and inflammation compared to AAC alone.
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Veterinary Sciences
·
2025
·Vol. 12
·期 3
·233
·
IF 2.3
Yang Yang,Xin Zhang,Jin Yang,Ziyan Wu,Junpeng Li,Ruilong Song,Chuang Meng,Guoqiang Zhu
Simple SummaryQuorum sensing (QS) not only regulates bacterial virulence through signaling molecules, but is also capable of causing direct damage to host cells. Previous studies have found a high correlation between N-acyl homoserine lactone (AHL) of the QS in the piglet intestine and piglet health. In a mouse model, AHL signaling N-(3-oxododecanoyl)-homoserine lactone (OdDHL) induced apoptosis of intestinal cells and damage to intestinal barrier. In a porcine intestinal epithelial cell model, OdDHL also was confirmed to induce apoptosis. The direct role and mechanism of OdDHL in the digestive tract of porcine animal models have not been elucidated. For the first time in a piglet model, we have verified that AHL induces apoptosis and disrupts the intestinal barrier, and we have also verified the protective effect of QS inhibitors. The present study also investigates the central role of cellular lipid rafts in the critical phase in which OdDHL adheres to cells and exerts functions. In cells where lipid rafts were eliminated, the ability of OdDHL adherence to cell surface was significantly reduced, and apoptosis induction was similarly impaired. This result indicates an important role for lipid rafts in relevant processes. This study provides basic data for the antimicrobial application of QSI in pig farming.Quorum sensing (QS) is a process by which bacteria sense their population density and regulate behavior accordingly. QS not only regulates bacterial virulence but also directly influences host cells. Previous studies have shown that QS is strongly associated with piglet intestinal health, but the mechanism is not yet clear. For the first time, we have confirmed in a piglet animal model that OdDHL directly damages intestinal cells in weaned piglets, disrupting the intestinal barrier. We also provide a preliminary exploration of the underlying mechanism of these effects. TUNEL assays confirmed that damage to the piglet intestinal barrier coincided temporally and spatially with dysregulated apoptosis. Lipid rafts, key components of the cell membrane, are involved in many biological processes, including the activation of apoptosis-related proteins. Following the disruption of the lipid raft structure in IPEC-J2 cells, the apoptosis rate under OdDHL stimulation decreased by 50%. These data demonstrate that lipid rafts mediate the attachment of OdDHL to porcine intestinal cells; then, OdDHL induces apoptosis in porcine intestinal cells through the mitochondrial and death receptor pathways, thereby compromising the integrity of the porcine intestinal barrier. This study provides foundational insights into the role of QS in piglet intestinal diseases.
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TALANTA
·
2024
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IF 5.6
Chen Cui,Yunfeng Fan,Yaxuan Chen,Renlong Wei,Jie Lv,Meng Yan,Dechen Jiang,Zhimin Liu
Cyanidin-3- O -glucoside (C3G), a natural antioxidant, plays multiple physiological or pathological roles in maintaining human health; thereby, designing advanced sensors to achieve specific recognition and high-sensitivity detection of C3G is significant. Herein, an imprinted-type electrochemiluminescence (ECL) sensing platform was developed using core-shell Ru@SiO 2 -CMIPs, which were prepared by covalent organic framework (COF)-based molecularly imprinted polymers (CMIPs) embedded in luminescent Ru@SiO 2 cores. The C3G-imprinted COF shell not only helps generate a steady-enhanced ECL signal, but also enables specific recognition of C3G. When C3G is bound to Ru@SiO 2 -CMIPs with abundant imprinted cavities, resonance energy transfer (RET) behavior is triggered, resulting in a quenched ECL response. The constructed Ru@SiO 2 -CMIPs nanoprobes exhibit ultra-high sensitivity, absolute specificity, and an ultra-low detection limit (0.15 pg mL −1 ) for analyzing C3G in food matrices. This study provides a means to construct an efficient and reliable molecular imprinting-based ECL sensor for food analysis.
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Royal Society Open Science
·
2017
·Vol. 4
·期 12
·
IF 2.243
Ya-Qiong Wang,Shou-Bin Xu,Jian-Guo Deng,Li-Zhen Gao
The interfacial compatibility between compact TiO2 and perovskite layers is critical for the performance of planar heterojunction perovskite solar cells (PSCs). A compact TiO2 film employed as an electron-transport layer (ETL) was modified using 3-aminopropyl trimethoxy silane (APMS) hydrolysate. The power conversion efficiency (PCE) of PSCs composed of an APMS-hydrolysate-modified TiO2 layer increased from 13.45 to 15.79%, which was associated with a significant enhancement in the fill factor (FF) from 62.23 to 68.04%. The results indicate that APMS hydrolysate can enhance the wettability of γ-butyrolactone (GBL) on the TiO2 surface, form a perfect CH3NH3PbI3 film, and increase the recombination resistance at the interface. This work demonstrates a simple but efficient method to improve the TiO2/perovskite interface that can be greatly beneficial for developing high-performance PSCs.
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FOOD AND AGRICULTURAL IMMUNOLOGY
·
2018
·
IF 2.568
Fengyin Liu,Zijian Chen,Yudong Shen,Yuanming Sun,Jinyi Yang,Hong Wang,Hongtao Lei,Zhenlin Xu
Immunoassay direct for 3-amino-5-morpholinomethyl-2-oxazolidone (AMOZ), the metabolite of furaltadone, based on a specific antibody was usually unavailable due to its small molecule weight. In this work, a hapten with a double bond and an active carboxyl group was designed and then conjugated to peptide dendrimer to obtain novel multiple haptens. The haptens and multiple haptens were coupled to bovine serum albumin as immunogens. Polyclonal antibodies showed binding to free AMOZ in a heterologous competitive indirect enzyme-linked immunosorbent assay were obtained. The assay showed IC50 (half maximal inhibitory concentration) of 4.1 μg/kg and limit of detection of 0.2 μg/kg for AMOZ. Recoveries of AMOZ from grass carp were tested from 83.1% to 117.0%, with the coefficient of variation below 12%. As no laborious derivatisation procedure was employed, the proposed assay should be useful for the screening of AMOZ for a large number of samples.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2024
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IF 4.9
Dexu Liu,Shuangqing Fu,Wenzhi Xu,Xueyu Fan,Shuo Wang,Shengguo Duan,Wei Li,Honglei Zhang
The utilization of environmentally friendly biopolymer poly(3-hydroxybutyrate) (PHB) as a support for metal catalysts is an unexplored area. Herein, exploring a stable and recyclable heterogeneous palladium (Pd) catalyst based on PHB for the Suzuki cross-coupling reaction is an attractive topic. In this study, a novel hydrophobic and hydrophilic core-shell bead supported Pd catalyst was developed by using PHB particle as a hydrophobic rigid framework and hydrophilic chitosan (CS) as the surface of the supporting matrix to fix Pd nanoparticles (NPs). The results of structural characterization showed that the Pd NPs with a small average size of 2.3±0.82 nm were uniformly distributed on the surface of the PHB-CS bead with a Pd content of 0.12 wt%. This demonstrated that the PHB-CS bead created a stable coordinated environment for Pd fixation, preventing Pd leaching. Furthermore, the Pd@PHB-CS catalyst exhibited high catalytic efficiency with 99% conversion in the Suzuki reaction under mild conditions, using a solvent mixture of EtOH and H 2 O (1:1) for 0.5 h. It is worth noting that the catalyst exhibits excellent stability, and reusability. It can be reused five times without a significant reduction in activity while maintaining its structural integrity. The successful construction of Pd@PHB-CS will further expand the application of PHB in the field of metal catalysts and may help establish a green and environmentally friendly multifunctional platform for the development of highly recyclable heterogeneous catalysts containing metal nanoparticles.
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ENVIRONMENTAL POLLUTION
·
2024
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IF 7.6
Yingying Liu,Xudong Jin,Yanan Ye,Zeqiong Xu,Zhongkun Du,Huachang Hong,Haiying Yu,Hongjun Lin,Xianfeng Huang,Hongjie Sun
3-bromine carbazole (3-BCZ) represents a group of emerging aromatic disinfection byproducts (DBP) detected in drinking water; however, limited information is available regarding its potential cardiotoxicity. To assess its impacts, zebrafish embryos were exposed to 0, 0.06, 0.14, 0.29, 0.58, 1.44 or 2.88 mg/L of 3-BCZ for 120 h post fertilization (hpf). Our results revealed that ≥1.44 mg/L 3-BCZ exposure induced a higher incidence of heart malformation and an elevated pericardial area in zebrafish larvae; it also decreased the number of cardiac muscle cells and thins the walls of the ventricle and atrium while increasing cardiac output and impeding cardiac looping. Furthermore, 3-BCZ exposure also exhibited significant effects on the transcriptional levels of genes related to both cardiac development ( nkx2.5 , vmhc , gata4 , tbx5 , tbx2b , bmp4 , bmp10 , and bmp2b ) and cardiac function ( cacna1ab , cacna1da , atp2a1l , atp1b2b , atp1a3b , and tnnc1a ). Notably, N-acetyl-L-cysteine, a reactive oxygen species scavenger, may alleviate the failure of cardiac looping induced by 3-BCZ but not the associated cardiac dysfunction or malformation; conversely, the aryl hydrocarbon receptor agonist CH131229 can completely eliminate the cardiotoxicity caused by 3-BCZ. This study provides new evidence for potential risks associated with ingesting 3-BCZ as well as revealing underlying mechanisms responsible for its cardiotoxic effects on zebrafish embryos.
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JOURNAL OF FOOD SCIENCE
·
2024
·Vol. 89
·期 6
·3183-3193
·
IF 3.2
Shen Duan,Narantsetseg Byambaakhuu,Na Han,Wenguang Zhang,Wenrui Guo,Chao-Mei Ma
The stems of Cynomorium songaricum are used in traditional Chinese medicine as a tonic and also used locally as a food material and livestock feed. It is known that some of the falvan-3-ol monomers and dimers that entered the milk of dairy sheep fed with C. songaricum stems are biotransformation products of the original flavan-3-ol polymers in C. songaricum stems. This study was performed to investigate the biotransformation process of the flavan-3-ols in dairy sheep and to evaluate the bioactivities. The results showed that procyanidin A2 and epicatechin could be released from the polymeric flavan-3-ols of C. songaricum through rumen microbial metabolism. On traumatic and lipopolysaccharide (LPS)-induced inflammation models of Tg (mpx: EGFP) zebrafish larvae and LPS-induced liver injury models of Tg (fabp10a: DsRed) zebrafish larvae, the milk from sheep fed with C. songaricum stems showed stronger anti-inflammatory and hepatoprotective activities compared to blank milk. The absorbed chemical constituents of C. songaricum stems and the metabolites also exhibited anti-inflammatory and hepatoprotective activities, with the dimeric flavan-3-ols being more effective than the monomers. The milk, the absorbed chemical constituents of C. songaricum stems, and the metabolites alleviated the increased level of reactive oxygen species induced by LPS in zebrafish larvae. Practical Application This study found that C. songaricum stems as livestock feed could produce milk that has a beneficial impact on consumer and livestock health in terms of anti-inflammation and hepatoprotection.
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JOURNAL OF MOLECULAR STRUCTURE
·
2024
·
IF 4
Xueqi Duan,Guona Li,Zhijian Jia,Hongzhen Xie,Xing Li
Copper is an essential element in the human body. Excess accumulations of copper, however, would become a potential threat. Therefore, it is of great significance to detect copper ions. Owing to their controllable morphology, dispersal characteristics, high extinction coefficient, and easily functionalized surfaces, gold nanoparticles (AuNPs) have been highly employed as attractive sensing probes for environmental and biological analyses. We herein propose an eco-friendly colorimetric strategy based on AuNPs modified with 3-pyridinylboronic acid (PA) for sensitive and selective detection of copper ions (Cu 2+ ) in water at trace level. The color changes of the system from wine-red to gray-blue with increasing amounts of copper ions is due to the binding of AuNPs modified with 3-pyridinylboronic acid to copper ions, which in turn leads to the aggregation of AuNPs with fine anti-interference. Strengths of the work: 1) rapid response time without complex pre-treatment; 2) high sensitivity with low limit of detection (LOD) and the good linear relationship ( R 2 = 0.98, LOD = 3.0 μM by the naked eye and 72 nM by ultraviolet-visible spectroscopy); 3) high selectivity under other interfering ions. In addition, the detection mechanism of this work has been successfully confirmed by density functional theory (DFT), transmission electron microscopy (TEM), dynamic light scattering (DLS), X-ray diffraction (XRD), Zeta potential analysis and ultraviolet-visible spectroscopy (UV–vis).
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危险品化学品经营许可证（带存储）