Nature Communications
·
2025
·Vol. 16
·期 1
·1-12
·
IF 15.7
Li Chun-Bo,Wang Fang,Wang Yi-Yang,Guo Mei-Lin,Li Jin-Le,Deng Cong,Song Fei,Yang Wei,Wang Yu-Zhong
Superamphiphobic and flame-retardant fabrics offer effective protection for firefighters and industrial workers operating under hazardous conditions. However, limitations in deformation resistance, wear comfort, and environmental adaptability hinder their practical applications. Here, a monolithic hierarchical macro-/micro-/nanostructure is constructed to achieve durable repellency against water and oils, even under significant deformations. This coating integrates fluorinated nanoparticles, flame retardant microparticles, and a cross-linking adhesive. Hydrogen bonding and the adhesive define the coating’s morphology, robustness, and adaptability. The coated surface exhibits an ultralow water adhesion force (0.002 mN) and excellent anti-fouling performance against extreme temperatures (100 °C, −196 °C) and corrosive liquids, including aqua regia and concentrated H 2 SO 4 . Upon fire exposure, the coating enables self-extinguishing behavior on cotton fabrics. The coated fabrics also demonstrate remarkable mechanical and UV resistance while preserving wear comfort. Overall, we achieve a balance between desirable properties and wear comfort in superamphiphobic, flame-retardant fabrics, enabling protective clothing applications previously unattainable.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Scientific Reports
·
2024
·Vol. 14
·期 1
·1-15
·
IF 3.8
Chen Linli,Guo Xiaojing,Lin Wen,Huang Yingying,Zhuang Suling,Li Qianfeng,Xu Jianhua,Ye Shengnan
Lytic induction therapy was devised to selectively combat malignancies associated with Epstein–Barr virus (EBV) by triggering viral reactivation from latency. At present, the major challenges of lytic induction therapy are to maximize reactivating efficiencies and meanwhile minimize infectious virion production. C210, a novel curcumin derivative with potent Hsp90 inhibitory activity, was explored for EBV-reactivating and virion-producing effects in EBV-positive nasopharyngeal carcinoma (NPC) and gastric carcinoma (GC) cell lines. And the molecular mechanisms underlying these effects were determined. Follow C210 treatment, EBV lytic RNAs and proteins were upregulated, but infectious virions were not produced. Knockdown of heat shock protein 90 (Hsp90) induced expression of lytic RNAs and proteins, and diminished C210-driven EBV lytic induction. Pretreatment with an X box binding protein 1 (XBP1) inhibitor reduced C210-induced EBV lytic RNA. Furthermore, we demonstrated that C210 inhibited the binding of Hsp90 with its clients, signal transducer and activator of transcription 3 (STAT3) and xeroderma pigmentosum group B-complementing protein (XPB), which subsequently promoted their proteasomal degradation. Degradation of STAT3 by C210 enhanced the EBV-reactivating and anticancer capacity of suberoylanilide hydroxamic acid (SAHA). Depletion of XPB blocked SAHA-induced expression of late viral genes and production of infectious virions. These results elucidate a novel Hsp90 inhibitor targeting EBV lytic phase and extend the research on lytic induction strategy, which may offer reference value in the treatment of EBV-positive malignancies.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
WATER AIR AND SOIL POLLUTION
·
2024
·Vol. 235
·期 9
·1-11
·
IF 3.8
Wei Hongyan,Li Xuejiao,Chen Lizhu,Li Shujie,Liu Hongxu,Song Tiehong
At present, the visible light (Vis) catalytic oxidation, as a wastewater treatment approach without secondary pollution, has captured the interest of many researchers. However, the efficiency of visible photocatalysis still needs to be continuously improved. In this study, a piezoelectric photocatalyst Bi 2 WO 6 (BWO) responding to both Vis and ultrasound (US) was prepared, characterized, and employed to treat Rhodamine B (RhB) in water. The removal efficiencies of RhB under different systems (Vis/BWO, US/BWO, (Vis + US)/BWO) were investigated and the reuse capacity of BWO were examined. Moreover, the piezoelectric photocatalytic mechanism of (Vis + US)/BWO system on RhB removal was analyzed. The results exhibited that the prepared Bi 2 WO 6 possessed excellent photoresponsive and piezoresponsive properties, and the removal and mineralization of RhB could reach 100% and 77.2% within 60 min, respectively. Under the combined effect of photocatalysis and piezoelectricity, the superoxide radicals, hydroxyl radicals, and photogenerated holes produced, which were responsible for the degradation of RhB in (Vis + US)/BWO system. Graphical Abstract
✓ 已验证
产品关联
DOI
高影响因子
International Journal of Peptide Research and Therapeutics
·
2024
·Vol. 30
·期 5
·1-13
·
IF 2
Liu Ziyang,Wei Yuping,Zhang Man,Zhu Xingyan,Liu Kun
Angiotensin-converting enzyme-2 (ACE2) is a important cell surface receptor of SARS-CoV-2 S protein. The initial stage of SARS-COV-2 cell infection involves the binding of the S protein to ACE2. Hence, this work presents an innovative strategy to designing ACE2-based peptide inhibitors by considering the surface property and morphology of the S protein RBD. The aim is to develop a short peptide inhibitor that can effectively inhibit S protein-ACE2 interaction Through computational analysis and molecular simulation, the surface properties and morphology of S protein receptor-binding structural domain (RBD) were investigated, while the key residues of ACE2 ligand-binding structural domain (LBD) were identified based on their contributions and non-covalent interactions. Then, peptide inhibitors, consisting of ACE2 key residues, were developed by fitting to the surface characteristics and topographical features of the S protein RBD. Molecular simulation showed that two novel short peptides, IEPFF (I5) and WIEPFF (W6) had high affinity for S protein RBD but a low affinity for the cell membrane. Cellular adsorption studies demonstrated that both I5 and W6 effectively blocked ACE2-S protein binding without significant cytotoxicity. Flow cytometry analysis revealed that both I5 and W6 effectively inhibited S protein binding to the ACE2, resulting in a significant reduction (75 and 79%, respectively) in fluorescence intensity after 30 min of incubation at a concentration of 200 μM. Both I5 and W6 were excellent potential anti SARS-COV-2 drugs. This work provides an innovative perspective for the development of functional peptides for the prevention and management of SARS-COV-2.
✓ 已验证
产品关联
DOI
高影响因子
CELLULOSE
·
2024
·Vol. 31
·期 10
·6551-6564
·
IF 4.9
Ding Qi,Liu Jiang-long,Liu Yan-Yan,He Wen-Zhan,Zhang Lin,Xu Ying-Jun
For addressing the issue of limited durable antibacterial cotton fabric, this study developed and synthesized quaternary ammonium salt antimicrobial agents. The chemical structure was analyzed by FTIR and 1 H NMR. The cotton fabric was subjected to surface modification techniques, such as pad-dry-cure, following the careful selection of appropriate quaternary ammonium salt. The chemical state and surface morphology were evaluated through XPS and SEM. Furthermore, the cotton fabric underwent comprehensive assessments, which included antibacterial testing, laundering cycle testing, evaluation of mechanical properties, and analysis of comfort performance. The results demonstrated that the treated cotton fabric achieved a high bacteriostatic and fungistatic rate of 99.99%, 87.5%, and 99.99% against S. aureus , E. coli , and C. albicans respectively even after 50 laundering cycles, while maintaining exceptional antibacterial effectiveness and laundering durability due to the formation of covalent bonds with the cotton fabric. The treated cotton fabric met AAA grade standards for antibacterial rate without causing any significant decline in mechanical properties. Furthermore, enhancements in hydrophilicity, softness, and wrinkle resistance were observed.
✓ 已验证
产品关联
DOI
高影响因子
Scientific Reports
·
2024
·Vol. 14
·期 1
·1-12
·
IF 3.8
Wang Hui-Hui,Yin He-Liang,Yin Wei-Wei,Song Yong-Li,Chen Hong
This study introduces a novel approach for synthesizing a Cu(II)-based coordination polymer (CP), {[Cu(L)(4,4´-OBA)]·H 2 O}n ( 1 ), using a mixed ligand method. The CP was successfully prepared by reacting Cu(NO 3 ) 2 ·3H 2 O with the ligand 3,6-bis(benzimidazol-1-yl)pyridazine in the presence of 4,4´-H 2 OBA, demonstrating an innovative synthesis strategy. Furthermore, a novel hydrogel composed of hyaluronic acid (HA) and carboxymethyl chitosan (CMCS) with a porous structure was developed for drug delivery purposes. This hydrogel facilitates the encapsulation of CP 1 , and enables the loading of paclitaxel onto the composite to form HA/CMCS-CP 1 @paclitaxel. In vitro cell experiments demonstrated the promising modulation of thyroid cancer biomarker genes S100A6 and ARID1A by HA/CMCS-CP 1 @paclitaxel. Finally, reinforcement learning simulations were employed to optimize novel metal–organic frameworks, underscoring the innovative contributions of this study.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2024
·
IF 0
Deb Hridam,Hasan Md Khalid,Islam Md Zahidul,Yang Shujuan,Zhang Yong,Yao Juming
Graphene-based adsorbent was prepared by adopting a green synthetic route via the chemical exfoliation of graphite and low-temperature thermal activation. Prepared reactive graphene (RG) was characterized through various techniques, and its adsorption capabilities for textile dye removal were investigated for Acid Blue-93 (AB) and Reactive Red-195 (RR) under different operational conditions. The dye sorption equilibrium and mechanism were comprehensively studied using isotherm and kinetic models and compared statistically to explain the sorption behavior. Results show AB and RR adsorption by RG attains equilibrium in 60 min and 70 min, with a high sorption quantity of 397 mg g −1 and 262 mg g −1 (initial dye concentration of 100 mg L −1 ), respectively. The dye sorption anticipates that the high surface area (104.52 m 2 gm −1 ) and constructed meso-macroporous features of RG facilitated the interaction between the dye molecules and graphitic skeleton. The R-P isotherm fitted the best of equilibrium data, having the least variance in residuals for both dyes (AB = 0.00031 and RR = 0.00047). The pseudo-second order model best fitted the kinetics of sorption on RG, with chemisorption being the predominant process delimiting step. The overall results promise the dye removal capability of RG to be an efficient adsorbent for azo-based dyes from textile effluents.
✓ 已验证
产品关联
DOI
PubMed
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2024
·Vol. 35
·期 25
·1-18
·
IF 2.8
Tang Meng,Zheng Lijia,Ge Ming
BiVO 4 photocatalysts with distinct morphology were solvothermally prepared by regulating the pH of precursor solution. The physicochemical properties of BiVO 4 catalysts were characterized using XRD, SEM, EDS, FT-IR and UV-Vis DRS. With the assistance of peroxydisulfate (PDS), as-obtained BiVO 4 could effectively degrade the cationic dye rhodamine B (RhB) and the anionic dye methyl orange (MO) under visible-LED-light illumination. RhB degradation obeys the first-order kinetic, while MO degradation complies with the second-order kinetic. Short stick-like BiVO 4 (named as BiVO 4 -1) showed the best RhB degradation efficiency, and sheet-like BiVO 4 (named as BiVO 4 -9) had the highest MO degradation rate. The influence of some important operating factors (PDS dose, BiVO 4 dosage, temperature, inorganic anions and humic acid) on the degradation of RhB and MO were discussed. In the BiVO 4 -1/PDS/Vis system, the free radical pathway (O 2 •‒ , SO 4 •‒ , •OH) and the non-radical pathway ( 1 O 2 and h + ) acted together to realize the degradation of RhB; however, in the BiVO 4 -9/PDS/Vis system, MO degradation was mainly dominated by the non-radical oxidation pathway ( 1 O 2 and h + ).
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2025
·Vol. 16
·期 1
·1-10
·
IF 15.7
Lu Shuo,Liu Yashuang,Dong Jinfeng,Li Xuefeng
Here are described the dilution-driven gel-sol-gel-sol transitions in aromatic hydrotrope/zwitterionic surfactant bi-component aqueous mixtures. Long and entangled wormlike micelles (WLMs) of concentrated erucyl dimethyl amidopropyl betaine (EAPB) solutions sequentially transform into hexagonal liquid crystal phase (H 1 ), highly concentrated spherical micelles (HCSMs), and finally hexagonal close packed micellar phase (HCP) upon gradual introducing an aromatic hydrotrope, sodium salicylate (NaSal). The HCP then successively converts into HCSMs, WLMs, and spherical micelles (SMs) upon further dilution with water, corresponding to a gel-sol-gel-sol transition. This dilution-induced HCSMs to WLMs transition results in an interesting thickening process, which is caused by a slow kinetic process, from the agglomeration and recombination of SMs to long and rigid WLMs via the intermediately formed rodlike micelles. In this work, the sustained adjustment of the competitive self-sorting and co-assembly between hydrotropes and surfactants by dilution was identified, benefitting the creation and application of WLMs fluids with switchable viscosity.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
METALLURGICAL AND MATERIALS TRANSACTIONS B-PROCESS METALLURGY AND MATERIALS PROCESSING SCIENCE
·
2024
·
IF 2.4
Yang Huan,Meng Chaosong,Wei Xiaohui,Xiong Heng,Kong Xiangfeng,Yang Bin,Xu Baoqiang,Dong Zhaowang,He Yuhong
Lead sulfide (PbS) has substantial potential for applications in many fields, such as optical devices and solar cells. Although PbS can be obtained from complex lead-antimony sulfide ores by vacuum distillation, the evaporation mechanism of PbS under vacuum is still unclear. Herein, the evaporation kinetics of PbS at 973 K to 1173 K and 5 to 1000 Pa were investigated using a vacuum thermogravimetric furnace. The practical evaporation rate of PbS was obtained through linear and nonlinear fitting of the experimental data compared with the original theoretical evaporation rate and corrected for the Langmuir maximum evaporation coefficient. The evaporation coefficients and critical pressures of PbS at 973 K, 1023 K, 1073 K, 1123 K, and 1173 K were 0.5225, 0.4056, 0.2080, 0.1995, and 0.1007 as well as 12.49, 16.67, 20.83, 24.19, and 30.15 Pa, respectively. Experimental results indicate that the evaporation rate conforms to the logistic nonlinear model, and the critical pressure is positively correlated with temperature. This paper provides a kinetic data base for PbS vacuum evaporation and also provides a reference for improving the process conditions and production equipment parameters of PbS vacuum distillation. Meanwhile, it improves and develops the theory and practice of vacuum distillation for the preparation of high-purity sulfides and fills the gap of basic kinetic data of nonferrous sulfides.
✓ 已验证
产品关联
DOI
高影响因子
IONICS
·
2024
·Vol. 30
·期 12
·8129-8145
·
IF 2.4
Wang Qiqi,Zhang Jingchun,Chen Haoyuan,Zhang Yilin,Wang Ying,Zhao Huimin,Zhu Yu,Wang Guowei,Zhuang Linghua
Ionic liquids (ILs) represent a suitable category of electrolytes in new energy batteries and supercapacitors. Although mono-cation ionic liquids have been extensively studied, the electrochemical properties of Gemini ionic liquids (GILs) have not been thoroughly explored. In this study, GILs containing functional hydroxyl group in spacer chain and different alkyl chain in imidazolium cation were synthesized. The physicochemical properties, including melting point, density, thermogravimetric (TGA) analysis, electrical conductivity (EC), molar electrical conductivity, and electrochemical stability window (ESW) of GILs, were evaluated. The introduction of hydroxyl group on spacer chain enhanced the melting point and ESW, while decreased the density, EC, and the thermal stability of bis(trifluoromethyl sulfonyl)imide (TFSI)-based GILs. ESW of TFSI-based GILs increased as the length of alkyl chain changed from methyl to butyl. TFSI-based GILs showed wider ESW than those of Gemini imidazolium bromide salts. Density functional theory (DFT) was used to study the relationship between the change of structure (hydroxyl group in spacer chain, alkyl chain length, and anions) and ESW values of GILs. These results will shed light on potential application of TFSI-based GILs in batteries as lithium-ion or supercapacitors as electrolytes.
✓ 已验证
产品关联
DOI
高影响因子
METALLURGICAL AND MATERIALS TRANSACTIONS B-PROCESS METALLURGY AND MATERIALS PROCESSING SCIENCE
·
2024
·
IF 2.4
Chen Mao,Dong Xiaosen,Pu Shuiqiang,Tang Wenbo,Zheng Kui
Na 2 O and K 2 O alkaline oxide capacities of TiO 2 -bearing blast furnace slags are critical values for vanadium titanomagnetite blast furnace operation. In this study, high-temperature experiments with fast-quenching were conducted to investigate the effects of TiO 2 concentration, basicity, MgO and Al 2 O 3 concentrations on Na 2 O and K 2 O concentrations in the TiO 2 -bearing blast furnace slags. The results were correlated with optical basicity and also compared with the plant data from one commercial vanadium titanomagnetite blast furnace.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）