ANALYTICAL LETTERS
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2020
·
IF 1.467
Xiaohong Shi,Xuehong Ren,Ning Jing,Jialin Zhang
A sensitive and selective molecular-imprinted electrochemical sensor was developed for the determination of ampicillin. The molecularly imprinted film was electropolymerized on the surface of a glassy carbon electrode modified with gold nanoparticles (AuNPs) and single walled carbon nanotubes (SWCNTs) using ampicillin as the template molecule and o-phenylendiamine as the functional monomer. Under the optimized conditions, the current change of this electrode showed a linear relationship with the ampicillin concentration from 5.0 × 10−8 mol/L to 1.0 × 10−5 mol/L and a detection limit of 1.0 × 10−9 mol/L. Due to the increased specific surface areas and conductivity of the AuNPs and SWCNTs, this sensor exhibited excellent sensitivity for ampicillin. The recovery values for ampicillin detection in milk using the developed sensor were from 95.0% to 98.1%.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2020
·
IF 3.573
Guokai Cui,Shuzhen Lyu,Fengtao Zhang,Huiyong Wang,Zhiyong Li,Yanan Li,Jianji Wang
In this contribution, a series of ionic liquids (ILs) with tri-n-butylethyl-phosphonium cation ([P4442]) and functional anions are designed and prepared, including pyridinolate anion ([PyO]), pyridinecarboxylate anion ([PyCOO]), and pyridinesulfonate anion ([PySO3]). Each anion contains both N site and O site, which can react with SO2. It could be found that up to 4.71 mol SO2 mol–1 IL absorption capacity could be received by [P4442][PyO] at 20 °C and 1 bar. Compared to ILs with phenolate anion ([PhO]), benzoate anion ([PhCOO]), and benzenesulfonate anion ([PhSO3]), the pyridine-based counterparts in this work were found to significantly enhance SO2 capture capacity, especially for anions with high basicity. It was demonstrated from the combination of FT-IR and NMR spectroscopic investigations and DFT calculations that the simultaneous cooperative interaction of N···SO2 and O···SO2 between functional anion [PyO] and SO2 was the main reason for high absorption capacity of low-concentration SO2 by [P4442][PyO].
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POLYMERS & POLYMER COMPOSITES
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2020
·
IF 1.023
Yawen Fang,Yanbin Wang,Yongchao Li,Huang Yu,Changlong Zhuang,Zhonglin Luo,Zicheng Fan,Biaobing Wang
A series of novel ternary conductive composites have been prepared by incorporating functionalized multiwalled carbon nanotubes (FMWCNTs) into the binary composites of poly(amide-imide) (PAI) and poly(o-methoxyaniline) (POMA) to further improve the conductivity of PAI composites. With increasing the weight ratio of FMWCNTs, the conductivity of PAI/POMA/FMWCNTs ternary composites has been significantly enhanced from 10−3 S m−1 to 90 S m−1, much higher than that of the sum of PAI/POMA and PAI/FMWCNTs binary composites. The enhanced conductivity is mainly ascribed from a much more intensive conductive network formed in the PAI/POMA/FMWCNTs ternary composites. It is found that the N–H bending of amide group in the Fourier transform infrared spectrometry spectra is observed at 3298 cm−1 for PAI, 3296 cm−1 for PAI/POMA binary composites, and further blue shifted to 3292 cm−1 for PAI/POMA/FMWCNTs ternary composites. Moreover, the glass transition temperature has been increased from 82.5°C to 117.7°C. These results suggested that the hydrogen bonding interaction has been strengthened among PAI, POMA, and FMWCNTs, which is useful for dispersion of condcutive fillers into the polymer matrix.
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TALANTA
·
2020
·
IF 5.339
Qinzhi Wang,Rui Li,Yijian Zhao,Taotao Zhe,Tong Bu,Yingnan Liu,Xinyu Sun,Huifan Hu,Meng Zhang,Xiaohan Zheng,Li Wang
Covalent organic frameworks (COFs) have attracted tremendous interest due to their promising applications, including electrocatalysis originating from their unique structural features. However, it remains a challenge to prepare COFs for p-nitrophenol (PNP) and o-nitrophenol (ONP) electrocatalysis because it is quite difficult to manipulate their dimension, composition , and morphology with abundant active sites. Here, a facile ambient temperature synthesis of unique Fe 3 O 4 -based magnetic COFs nanosphere (Fe 3 O 4 @AT-COFs) with different surface morphologic structure is reported, which exhibits higher surface area, good water dispersity, long-term stability, excellent electrical conductivity and pre-concentration effect. The prepared Fe 3 O 4 @AT-COF-based electrochemical sensor is then directly employed for the simultaneous detection of PNP and ONP with a wide linear detection range of 10–3000 μM and low detection limits (LOD) of 0.2361 μM and 0.6568 μM, respectively. Meanwhile, the Fe 3 O 4 @AT-COF can be also well-applied in lake and tap water for monitoring PNP and ONP with outstanding sensitivity and reliability, which is expect to be a high-efficient electrocatalyst with great promise for signal amplification of electrochemical sensing.
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高影响因子
FOOD RESEARCH INTERNATIONAL
·
2021
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IF 6.475
Yajiao Zhao,Wenli Wei,Li Tang,Dongdong Wang,Yan Wang,Zhengyun Wu,Wenxue Zhang
Sichuan industrial paocai and traditional home-made paocai have different aroma profiles due to different manufacturing techniques, but detailed information about the aroma profiles and aroma-producing microorganism of Sichuan industrial paocai remain largely elusive. For this reason, we established and validated an external standard method of headspace solid-phase microextraction gas chromatography-mass spectrometry (HS-SPME-GC–MS) combined with gas chromatography–olfactometry (GC-O) for identification and accurate quantitation of aroma-active compounds in Sichuan industrial paocai. This method was combined with 16S rRNA amplicon sequencing to comprehensively analyze the aroma and bacteria profiles of Sichuan industrial paocai. A total of 121 volatile compounds were identified, among which 36 odorants were identified as aroma-active compounds with aroma intensities (AIs) ranging from 0.67 to 5.00 by GC-O. The types of aroma-active compounds in Sichuan industrial paocai were variety-specific to some extent, but the aroma-active compounds shared by different varieties of Sichuan industrial paocai (i.e., skeleton aroma-active compounds) were phenylethyl alcohol, acetic acid, butanoic acid, 2-methylbutanoic acid, ethyl hexanoate, 4-ethylphenol and 4-ethylguaiacol. Moreover, 17 key aroma-active compounds of AI > 1 in radish paocai were quantitated by external standard method, and their odor activity values (OAVs) were calculated based on the odor thresholds. Further, 12 aroma-active compounds with OAV ≥ 1 in one of the radish paocai were selected to construct the recombination model, which revealed good agreement with the original sample. Furthermore, Lactobacillus, Pediococcus, Pseudomonas and Sphingomonas were the dominant bacteria in Sichuan industrial paocai. Correlation analysis between 16 dominant bacteria and 36 aroma-active compounds showed that Pediococcus, Arcobacter and Lactobacillus could be the core aroma-producing bacteria of Sichuan industrial paocai.
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DRUG DELIVERY
·
2021
·
IF 6.419
Jianbo Li,Tiange Feng,Weijing Yang,Yaru Xu,Shuaishuai Wang,Huijie Cai,Zhilei Liu,Hong Qiang,Jinjie Zhang
Although Fraxinellone (Frax) isolated from Dictamnus albus L. possessed excellent anti-hepatic fibrosis activity, oral administration of Frax suffered from the inefficient therapeutic outcome in vivo due to negligible oral absorption. At present, the oral formulation of Frax is rarely exploited. For rational formulation design, we evaluated preabsorption risks of Frax and found that Frax was rather stable while poorly dissolved in the gastrointestinal tract (78.88 μg/mL), which predominantly limited its oral absorption. Further solubility test revealed the outstanding capacity of cyclodextrin derivatives (CDs) to solubilize Frax (6.8–12.8 mg/mL). This led us to study the inclusion complexes of Frax with a series of CDs and holistically explore their drug delivery performance. Characterization techniques involving 1H-NMR, FT-IR, DSC, PXRD, and molecular docking confirmed the most stable binding interactions when Frax complexed with 6-O-α-D-maltosyl-β-cyclodextrin (G2-β-CD-Frax). Notably, G2-β-CD-Frax exhibited the highest solubilizing capacity, fast dissolution rate, and superior Caco-2 cell internalization with no obvious toxicity. Pharmacokinetic studies demonstrated markedly higher oral bioavailability of G2-β-CD-Frax (5.8-fold that of free drug) than other Frax-CDs. Further, long-term administration of G2-β-CD-Frax (5 mg/kg) efficiently inhibited CCl4-induced hepatic fibrosis in the mouse without inducing any toxicity. Our results will inspire the continued advancement of optimal oral Frax formulations for anti-fibrotic therapy.
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PubMed
高影响因子
DYES AND PIGMENTS
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2019
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IF 4.018
Xiuquan Xu,Songmei Wang,Tongjie Hu,Xiaofeng Yu,Jiapeng Wang,Chao Jia
Co-doping has been proven to significantly enhance the photocatalytic performance of g-C 3 N 4 . Herein, Mn and O co-doped g-C 3 N 4 (Mn/O-CN) composites were constructed for the first time by a simple one-pot calcining route. The systematic characterization results of XRD , FT-IR, TEM-EDS, XPS and DRS revealed that the Mn and O elements were co-doped into the CN framework successfully as Mn 3+ / 4+ and n-π* conjugate forms, respectively. The as-prepared Mn/O-CN-2 achieved the highest visible-light-driven degradation rate constant of 0.0290 and 0.0267 min −1 for degradation of Malachite green (MG) and Amido black 10B (AB 10B), which were about 5.09 and 5.45 folds higher than that of pristine CN, respectively. The improved photocatalytic degradation property of Mn/O-CN were mainly benefited from the extended visible light utilization, the enlarged specific surface area, and the accelerated separation and transfer of photo-induced charge carriers, which were all induced by the synergistic effects of Mn and O co-doped. Finally, the active species capturing experiments proved that the superoxide radicals (·O 2 − ) and holes (h + ) acted as the predominant roles in the photocatalytic degradation process .
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SENSORS
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2019
·Vol. 19
·期 3
·674
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IF 3.031
Hong Zhai,Yunfeng Bai,Jun Qin,Feng Feng
A novel colorimetric and ratiometric fluorescence sensor was constructed by using carbon quantum dots (CQDs) and o-diaminobenzene (ODB). Unlike ODB by itself, ODB oxide (oxODB) not only emits fluorescence, but also produces ultraviolet (UV) absorption. Therefore, on the basis of the potential optical properties of ODB, glucose oxidase (Gox) and horseradish peroxidase (HRP) were introduced into a CQDs–ODB system for the quantitative oxidation of ODB. When glucose is present, it is oxidized by oxygen under the catalytic action of its oxidase to form hydrogen peroxide. Hydrogen peroxide is a strong oxidant that can rapidly oxidize ODB through the catalysis of horseradish peroxidase. oxODB can cause changes in the fluorescence ratio (I550/I446) and absorbance ratio (A/A0). At the same time, the color of the detection solution can also change under sunlight and ultraviolet lamps. Therefore, glucose can be quantitatively detected by ratiometric fluorescence and colorimetry simultaneously, and semi-quantitatively detected by observing the colors with sunlight and ultraviolet lamps of 365 nm. This increases not only the convenience but also the accuracy of detection. In addition, this sensor has good selectivity and can be used for the determination of glucose in serum, providing a new idea for the development of blood glucose sensors.Keywords:dual-mode sensor;carbon quantum dots;o-diaminobenzene;glucose
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RSC Advances
·
2019
·Vol. 9
·期 28
·15694-15702
·
IF 3.049
Lijing Nan,Jiao Li,Wanjun Jin,Ming Wei,Mengjun Tang,Chengjian Wang,Guiping Gong,Linjuan Huang,Ying Zhang,Zhongfu Wang
Mass spectrometry (MS) analysis combined with stable isotopic labeling is of great importance for quantitatively profiling abnormal sialylated O-glycans associated with disease development, but technically hindered by the poor releasing efficiency of O-glycans from glycoprotein or the labile nature of sialic acid residues at glycans. Herein, we developed an isotopic precursor based metabolic amplification and labeling (IPMAL) technique for relative quantitative profiling of the repertoire O-glycans between normal and tumor cells by ESI-MS. Two groups of cells were incubated with peracetylated benzyl-α-N-acetylgalactosamine (Ac3GalNAc-α-Bnd0) or a heavy labeled peracetylated benzyl-α-N-acetylgalactosamine (Ac3GalNAc-α-Bnd5) precursor respectively to amplify the repertoire of O-glycans as Bnd0/d5-O-glycans which could achieve the quantitative O-glycome analysis by ESI-MS after derivatization. The established method demonstrates desirable feasibility, accuracy (relative error (RE) ≤ 4.20%), reproducibility (coefficient of variation (CV) ≤ 7.61%, n = 3) and good quantitation linearity (R2 > 0.99, n = 3) for five Bn-O-glycans with 2 orders of magnitude. Finally, the method has been successfully applied to quantitative analysis of the repertoire O-glycome changes between normal human liver cell line L02 and human hepatoma cell line SMMC-7721. Moreover, the α-2,3/2,6 sialic acid isomers of Bn-O-glycans from these two cells have been further quantitatively distinguished when involved a sialic acid specific derivatization procedure.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2019
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IF 4.175
Worku Lakew Kebede,Dong-Hau Kuo,Misganaw Alemu Zeleke,Kedir Ebrahim Ahmed
Environmentally toxic methylene blue organic pollutants are of more concerns due to their antagonistic effects on human health, animals, and plants, thus needs serious attention for their removal. For elimination purpose, the Sb-doped Mo(O,S) 3 oxy-sulfide nanoplate catalyst with different Sb contents was synthesized at low temperature of 95 °C via a facile method. The structural, morphological, chemical composition, optical properties , and electrical conductivity of the catalyst were characterized with different techniques. The photocatalytic performance of Sb-Mo(O,S) 3 at various Sb contents was investigated for the degradation of methylene blue dye under visible light irradiation using hydrogen peroxide as an effective electron scavenger to further accelerate the reaction. It was observed that the incorporation of Sb enhanced the catalytic activity. Sb-Mo(O,S) 3 -10 was the most efficient catalyst with excellent activity to degrade 99.7% of the dye within 60 min irradiation time. The degradation kinetics follows a pseudo-first-order reaction with a rate constant 8.78 × 10 −2 min −1 , which is 3-fold higher than that for Sb- Mo(O,S) 3 -0 catalyst. Sb-Mo(O,S) 3 -10 showed slower recombination of photogenerated charge carriers and lower charge transfer resistance which proved to be capable for the removal of toxic methylene blue organic pollutant.
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RENEWABLE ENERGY
·
2019
·
IF 5.439
Qing Zhou,Xinyan Zhong,Xingyue Xie,Xuanyi Jia,Baiquan Chen,Ning Wang,Lihong Huang
Biomass-derived acetic acid (HAc), as a hydrogen storage medium, can be transformed to hydrogen via on-board reformer for fuel cells. Steam reforming (SR) of HAc is a traditional hydrogen production process, but endothermicity of SR is a concern for heat management in dynamic on-board application. Auto-thermal reforming (ATR) of HAc is a promising route, while catalyst deactivation in harsh ATR atmosphere should be addressed. Samarium-promoted ordered mesoporous Ni-xSm-Al-O catalysts were synthesized via improved evaporation-induced self-assembly (EISA) method, and tested in ATR of HAc for hydrogen production. The Ni-2Sm-Al-O catalyst produced a stable HAc conversion near 100.0% and a hydrogen yield at 2.6 mol-H 2 /mol-HAc in a 30-h test. Meanwhile, the Ni-2Sm-Al-O catalyst shows resistance to oxidation , sintering and coking; this improved reactivity and durability can be attributed to basic Sm oxides and ordered mesoporous framework with confinement effect : the basic sites are beneficial to adsorption and activation of HAc, and the ordered mesoporous framework constrains the thermal agglutination of Ni metal and formation of coking, while intermediate carbonous species of *CH x (x = 0–3) can be gasified via the Sm 2 O 3 -Sm 2 O 2 CO 3 cycle. These Sm-promoted Ni-based catalysts are also tested with different temperatures and O/C, and show potentials in ATR of HAc for hydrogen production.
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NEW JOURNAL OF CHEMISTRY
·
2018
·Vol. 42
·期 11
·9140-9150
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IF 3.201
Jiliang Ma,Xinwen Peng,Linxin Zhong,Runcang Sun
The application of biomass-based carbonaceous solid acids in catalysis is attracting increasing attention in the field of chemistry. In this study, a heterogeneous carbon-based solid acid biocatalyst (CXH-SO3H) with regular spherical structure was synthesized from xylan-type hemicellulose (XH) by a simple two-step method. The catalyst was successfully applied in the synthesis of O- and N-heterocycles with yields of 80–99% and 60–97%, respectively. In view of environment and economy, CXH-SO3H shows the merits of environmental friendliness, easy operation, simple work-up, excellent yields, and the avoidance of use of organic solvents and expensive catalysts. Moreover, the as-synthesized solid acid catalyst could be used for several cycles without significant loss in its catalytic activity. The results of FT-IR, XRD, and SEM showed that no distinct differences in physico-chemical structures of CXH-SO3H were observed. Thus, the eco-friendly CXH-SO3H catalyst is a promising candidate for green synthesis of O- and N-heterocycles from low-cost feed-stocks and has good prospect in partially substituting commercially available solid and liquid acid catalysts and precious metal catalysts.
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危险品化学品经营许可证（带存储）