OPTIK
·
2022
·
IF 2.84
Xiang-Lin Fang,Rui-Tong Zhao,Na Chen,Xin Wang,Peng Wang,Zhi-Wei He,Shao-Xin Li,Yang Xu,Yong-Hong He
As one of important optical properties of chiral molecules, the real-time monitoring of the optical rotation is of great significance to study the reaction characteristics of chiral molecules. In this study, we have built an optical frequency domain weak measurement system with linear common-path method for chiral sensing, in which the response between optical rotation and central wavelength shift can reach more than 1200 nm/rad. The high-precision measurement of the optical rotation of chiral molecules and the high-sensitivity real-time monitoring of the decomposition rate in the acidic hydrolysis of sucrose under different concentrations of catalysts are realized using this system. The experimental results are basically consistent with the theoretical prediction. This study shows that optical weak measurement chiral sensing can monitor the hydrolysis degree of chiral molecules in real time without separating and labeling molecules. It has great application potential in the production and research of chiral compounds, especially chiral medicine.
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高影响因子
ELECTROCHIMICA ACTA
·
2022
·
IF 7.336
Sankar Sekar,Jiang Huijun,Zhou Liuzhu,Chen Jin,Sejoon Lee,Deuk Young Kim,Ramalingam Manikandan
Foodborne antioxidants including ascorbic acid (AA), caffeic acid (CA) and gallic acid (GA) are beneficial nutritional sources and thereby the analysis of the critical antioxidant is demanding for public health. Here, a sonochemical method was used to obtain hybrid copper-phthalocyanine conjugated graphitic carbon nitrides nanosheets (CuPTc/g-C 3 N 4 Ns) in which carboxylic acids and hydroxyl groups were added on the basal plane of g-C 3 N 4 . As prepared materials were characterized by various physicochemical and electroanalytical techniques, the CuPTc/g-C 3 N 4 Ns nanocomposite showed an excellent electrocatalytic activity towards antioxidants quantifications by using Indium Tin Oxide (ITO) coated glass plate. Under optimized experimental conditions, sensitive electrochemical detection of antioxidants was achieved on the CuPTc/g-C 3 N 4 Ns nanocomposite-modified ITO which resulted in wide linear concentration range of 0.05-500 µM (AA), 0.05-501 nM (CA) and 10-445 nM (GA) and the limit of detection (LOD) of 0.006 µM, 0.008 nM and 0.5 nM respectively. Furthermore, the fabricated sensor was successfully used for the antioxidants determinations in different commercial fruit juice, alcoholic beverages and tea samples with good recovery results demonstrating a hybrid phthalocyanine conjugated 2D carbon nanocomposite as an efficient electrocatalyst of desirable practical importance.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2022
·
IF 9.221
Yanmin Liang,Runli Li,Hao Sun,Jie Dan,Zehui Su,Yi Kang,Qiuping Zhang,Shuo Shi,Jianlong Wang,Wentao Zhang
Natural peroxidase composed of protein and metallic cofactor suffers from deactivation in harsh environment. Learning from the natural structure of active site in peroxidase, in this work, natural melanin nanoparticles from cuttlefish were facilely functionalized with Fe 3+ to construct peroxidase-like nanozyme , showing high stability and activity. In the presence of H 2 O 2 , Fe-melanin nanoparticles (Fe-NMPs) catalyzes the formation of·OH from H 2 O 2 , converting colorless 3,3,5,5-Tetramethylbenzidine (TMB) into blue oxidized TMB (ox-TMB). When the antioxidants were added into the system, ox-TMB will be reduced to colorless TMB, thus allowing the detection of total antioxidant capacity . The results show that the lowest detection limit of AA in Fe-NMPs is 12.61 μM and the detection range is 5–250 µm. The test results for AA were similar to the sample instructions for beverages and fruits, validating the feasibility of using Fe-NMPs for the actual total antioxidant capacity determination. This study provides a broader perspective for fabricating foodborne nanozyme for related applications.
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高影响因子
CELLULOSE
·
2022
·Vol. 29
·期 2
·879-891
·
IF 6.123
Zhou Liang,Liu Qiyu,Ma Qiaozhi,Guan Mingzhao,Ouyang Xinping,Qiu Xueqing
Abstract Saccharification of cellulose into glucose is a key step for the utilization of lignocellulose. Molten salt hydrate (MSH) is unique in selective hydrolysis of cellulose into glucose but the separation of formed glucose from MSH is challenging due to the high solubility of glucose in MSH. To address this issue, this work developed a method where a small dosage of MSH was applied to impregnate cellulose and convert it into water-soluble sugar with the degree of polymerization (DP) lower than 6, which can be readily hydrolyzed into glucose under mild conditions without sacrificing selectivity. Under the optimized impregnation condition at 110 °C for 2 h, cellulose was selectively converted into water-soluble sugar with a yield of 87.5%. Then the MSH can be efficiently dissolved and removed by anti-solvent isolation with n -butanol, resulting in a sugar recovery of 84.3%. We showed that the separation efficiency was influenced by anti-solvent polarity and oligosaccharides chain-length. Moreover, the production and separation of water-soluble sugar from corn stover was also investigated. 88.9% yield of water-soluble sugar was obtained from the impregnation of corn stover under the optimized reaction conditions. With the addition of n -butanol as an anti-solvent, the water-soluble sugar can be recovered from MSH with a selectivity of 86.7%. Graphical Abstract
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JOURNAL OF MOLECULAR LIQUIDS
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2022
·
IF 6.633
Shen Zhang,Caidi Jin,Kuichuan Sheng,Ximing Zhang
5-hydroxymethylfurfural (HMF) primary can be synthesized from monosaccharides including glucose and fructose, cost is one of barriers to realize HMF large-scale production. In this study, a high HMF yield of 69.6 mol% was obtained at 180℃ for 5 min using biomass derived cellulose formate as reactant, which was prepared by formylation of cellulose using recyclable formic acid, and sequentially catalyzed by hydrochloric acid (HCl) and aluminum chloride (AlCl 3 ) in dimethyl sulfoxide (DMSO) and H 2 O system. To investigate the effect of cosolvents and formyl groups on the cellulose formate conversion, kinetics analysis and molecular dynamics simulations were conducted. Reaction kinetics study shows that the rate constant of hydrolysis of cellulose formate to glucose increased by almost three times in DMSO-H 2 O and the reaction rates’ constants of glucose, fructose and HMF to humins decreased with the presence of DMSO. Molecular dynamics simulations show that formyl group and DMSO increased its hydrophilicity around the reactive hydroxyl group on the carbon ring and steric hindrance of formyl group affect the distribution of water molecular and DMSO molecular around formylated glucose, resulting in facilitating the formation of a precursor to fructose and inhibiting the formation of humins during formylated glucose conversion.
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SENSORS AND ACTUATORS B-CHEMICAL
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2022
·
IF 9.221
Dan Wang,Guanchen Xu,Xingshuang Zhang,Hongyu Gong,Li Jiang,Guanliang Sun,Yu Li,Guoran Liu,Yong Li,Shikuan Yang,Xiu Liang
A novel approach is developed to fabricate an ultra-thin layered flexible wearable Surface-Enhanced Raman Scattering (SERS) substrate named silk fibroin-anodic aluminum oxide-Au nanoparticles (SF-AAO-Au), which consists of biocompatible SF film as flexible support, ultrathin cavity AAO as template, and plasmonic Au NPs. The SF-AAO-Au sensor exhibits excellent SERS mechanical flexibility, homogeneity and sensitivity for its effective enhancement ability and highly ordered 3D periodic porous particle-in-cavity (PIC) arrays structure. The humidity-driven interface structure of biocompatible SF film provides good skin adhesion under various fitness tests and excellent mechanical flexibility as a wearable SERS sensor on natural skin (deformation within 5%). The flexible SF-AAO-Au can be developed as quantitative sweat glucose sensor in the concentration range of 10 − 7 to 10 − 3 M with a limit of detection (LOD) of 1.68 × 10 − 7 M and qualitative human sweat glucose detection ability. This SF-AAO-Au substrate can be further designed as lab-on-glove SERS sensing platform for ultrasensitive (LOD ~5.7 ppt) quantitative on-site detection of agricultural residues in a wide range. The effective dual-functional SERS wearable sensor realized for the first time paves a new way to develop smart wearable and non-destructive devices in environmental safety, forensic identification and point-of-care testing (POCT) diagnosis of physiological disease.
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ACS Sustainable Chemistry & Engineering
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2022
·
IF 9.224
Hui Yang,Chaonan Tao,Lincai Peng,Junhua Zhang,Liang He,Huai Liu
It remains a challenging task for the efficient conversion of carbohydrates to value-added chemicals at concentrated feedstock solution. In this contribution, the acid-catalyzed processing of high-concentration C5/C6 sugars (180 g/L) in the ethylene glycol (EG) solvent system was investigated, and prominent discrepancy was noticed between C5 and C6 sugars. A large amount of liquefied products was achieved in the concentrated C6 sugars EG solution, whereas the main products in the case of C5 sugars were found to be solid humins. The reaction mechanism studies revealed that EG can shelter fructose and reaction intermediates (5-hydroxymethylfurfural and levulinic acid) from the cross-polymerization and self-etherification reactions, thereby reducing the generation of solid humins during the fructose liquidation process. However, in the case of xylose, the copolymerization between EG and furfural (FF) generates a solid resin, thus rendering a high solid product yield. Moreover, the produced FF–EG resin was found to be a polymer with high molecular weight formed by connecting the furan ring and the alkyl structure through an ether bond. This finding provides insights into the acid-catalyzed conversion of concentrated C5/C6 sugars in EG, facilitating rationally designed processes for the valorization of concentrated carbohydrates.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
·
IF 5.518
Hongchao Ma,Yitong Chen,Zhaozhan He,Yanhui Wei
The Maillard reaction , a typical reaction between reducing sugars and amino-compounds, has been considered to be an excellent platform to construct fluorescent probes for detecting different analytes . In this work, an amino-modified hemicyanine dye, 4-(4-aminostyryl)-1-methylpyridinium iodide (ASMPI), has been synthesized as a probe for the fluorescent detection of glucose. The intramolecular charge-transfer (ICT) performance and fluorescence emission property of ASMPI was characterized by UV–vis and fluorescence spectra. According to FTIR and XPS results, the Maillard reaction occurred after adding glucose to ASMPI aqueous solution. The obtained Maillard reaction products resulted in the enhancement of fluorescence emission due to the weakening of ICT process. The effects of solvent polarity (adding ethanol) and temperature on the fluorescent emission of ASMPI-glucose Maillard products were investigated to further amplify their fluorescence signal. The results indicated that the optimal experimental condition were that the ratio of ethanol/water was 9:1 and the temperature was 40 °C. Based on this, a fluorescent assay for the detection of glucose was developed.
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ULTRASONICS SONOCHEMISTRY
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2022
·
IF 9.336
Chen Xing,Wen-Qiang Cui,Yue Zhang,Xin-Shu Zou,Jing-You Hao,Si-Di Zheng,Ting-Ting Wang,Xiao-Zhen Wang,Tong Wu,Yan-Yan Liu,Xue-Ying Chen,Shu-Guang Yuan,Zhi-Yun Zhang,Yan-Hua Li
Licorice ( Glycyrrhiza glabra ) is extensively used owing to the superior pharmacological effects. However, its maximum application potential has not been fully exploited due to the limitation of currently available extraction solvent and methods. In this study, an eco-friendly deep eutectic solvent (NADESs) based ultrasound-assisted extraction (DES-UAE) method was applied to prepare licorice extracts. The DES-UAE using choline chloride and lactic acid as solvent was optimized and modeled by using response surface methodology to maximize the extraction yields of glabridin (GLA) and isoliquiritigenin (ISL). The optimized extracts possessed higher contents of GLA and ISL than available extraction methods, and the enriched products showed superior pharmacological activities in vitro. Furthermore, scanning electron microscopy (SEM) and molecular dynamic simulation analyses were performed to deeply investigate the interaction between solvent and targeted compounds. This study not only provides an eco-friendly method for high-efficient extraction of GLA and ISL from licorice but also illustrates the mechanism of the increased extraction efficacy, which may contribute to the application of licorice and deep insight into extraction mechanism using DES.
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PubMed
高影响因子
BIOMEDICAL MICRODEVICES
·
2022
·Vol. 24
·期 1
·1-9
·
IF 3.783
Hu Tao,Wang Di,Xu Jian,Chen Ke,Li Xiao,Yi Hong,Ni Zhonghua
As one of the three major chronic diseases, diabetes often causes many complications, which can affect various parts of the body and even threaten the life of the patients. At present, the situation of diabetes in the world is quite serious. Accurate detection of blood glucose is very important for the diagnosis, treatment and medication of diabetes as well as the self-management of diabetic patients. In this paper, an electrochemical glucose biosensor was developed based on screen-printed electrode (SPE) modified with composite material of graphene aerogel (GA) and Prussian blue (PB) (denoted as GA@PB), which was fabricated via chemical reduction using L-ascorbic acid as a reducing agent through a freeze-drying process. Glucose was specifically captured by glucose oxidase (GOx) which were immobilized into the GA@PB by chitosan. The structure and performance of the sensor were characterized by scanning electron microscopy (SEM), Raman spectroscopy measurements, Fourier transform infrared spectrometer (FTIR), cyclic voltammetry (CV) and amperometric detection. The sensor exhibited a linear range of 0.5–6.0 mmol·L −1 with limit of detection (LOD) of 0.15 mmol·L −1 , indicating that the combination of graphene aerogel and Prussian blue possess well conductivity and catalytic performance.
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PubMed
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2022
·
IF 7.129
Ru Fan,Jianxing Xiang,Peipei Zhou,He Mei,Yanyan Li,Huili Wang,Xiaodong Liu,Xuedong Wang
As one kind of high nutrition fruits, abandoned Myrica rubra causes great waste due to short storage period. For resource utilization, we herein fabricated the Myrica rubra- based N-doped carbon dots (MN-CDs) by a facile/green hydrothermal method. MN-CDs, fabricated from four regions of China, displayed significant differences in their corresponding fluorescence intensities (FIs). Interestingly, different batches of waxberry samples from the same region (Wenzhou, China) exhibited slight differences in their FIs, and also an excellent anti-photobleaching and anti-salt capacity. Based on Fe 3+ -triggered quenching effect and fluorescent recovery by redox reaction of AA and Fe 3+ , MN-CDs were employed to construct an “on-off-on” switch probe for sequential detection of Fe 3+ and ascorbic acid (AA). Through Zeta potential, UV spectrum, Stern-Volmer equation, and valence-conduction band theory, the Fe 3+ -triggered quenching belonged to a static quenching process, which resulted from the synergistic contribution of inner filtering effect and photo-induced electron transfer mechanisms. The linear ranges for Fe 3+ and AA detections were 1–1000 and 0.1–1000 mM. The limits of detection were 0.3 μM for Fe 3+ in environmental waters, and 0.03 μM for AA in pharmaceutical tablets and fruit juice samples. Under 365-nm UV lamp, the color changes of test papers were easily observed from dark blue and bright blue in the presence of Fe 3+ and AA, and thus the MN-CDs-based switch probe could be satisfactorily used for visually qualitative detection of Fe 3+ and AA outdoor with our naked eyes. To sum up, MN-CDs not only realize resource reutilization of abandoned Myrica rubra , but also offer an convenient outdoor approach for qualitative detection of Fe 3+ and AA in complex matrices.
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PubMed
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2022
·
IF 4.598
Mingyue Chu,Zhenyuan Bai,Di Zhu,Wenjing Chen,Guixin Yang,Jianjiao Xin,Huiyuan Ma,Haijun Pang,Lichao Tan,Xinming Wang
β-nicotinamide adenine dinucleotide (NADH), as vital coenzyme involved, is expected to be accurately detected in Clinical diagnosis and treatment. Polyoxometalates (POMs) have unique redox capacity with good electrochemical reversibility and fast electron transfer ability, which makes them become favorite materials for sensors. Here by using alternating electrodeposition and self-assembly techniques, Keggin-type polyoxometalates (PMo 11 V) were modified on glassy carbon electrodes with the help of polyallylamine hydrochloride (PAH), to construct a sensitive and stable electrochemical sensor for detection of NADH. The proposed (PAH/PMo 11 V) 4 /GCE was characterized by scanning electron microscopy (SEM), atomic force microscopy (AFM), cyclic voltammetry (CV) measurements and amperometrics method (i-t). The obtained electrode has high stability, good reproducibility, outstanding sensing capability for NADH, with a low detection limit of 1.9 × 10 -8 M, a wide linear range from 3.2 × 10 -7 to 8.2 × 10 -5 M and 1.1 × 10 -5 to 1.01 × 10 -3 M. This strategy, overcoming the drawbacks of POMs and solving the shortcomings that NADH requires high electrocatalytic potential, is simple in operation, low in cost, and could be widely used in electrochemisty field.
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