JOURNAL OF MOLECULAR LIQUIDS
·
2020
·
IF 5.065
Kishore Chand,Dianxue Cao,Diaa Eldin Fouad,Ahmer Hussain Shah,Muhammad Nazim Lakhan,Abdul Qadeer Dayo,Hemant J. Sagar,Kai Zhu,Abdalla Mohamed Ali Mohamed
In this study, Acacia catechu (AC) extract was used as a stabilizing and reducing agent to synthesize silver (Ag) and titanium dioxide (TiO 2 ) nanoparticles (NPs). By using AC extract, the synthesis process becomes more environmental friendly, economical, and advantageous. The morphology and size of synthesized Ag and TiO 2 NPs were determined by X-ray diffraction (XRD), Transmission electron microscopy (TEM), Dynamic light scattering (DLS), Atomic force microscopy (AFM), and Scanning electron microscopy (SEM). Elemental composition was determined by using Fourier transform infrared spectroscopy (FTIR) and Energy dispersive X-ray spectrometer (EDX), EDS mapping and X-ray photoelectron spectroscopy (XPS). The observations from TEM, SEM, AFM, and DLS revealed that synthesized products are spherical, hexagonal, polydispersed, and ranged within 6–20 nm size. XRD result demonstrated well crystallized and smaller size NPs are formed in both cases. FTIR and XPS analysis depicted the presence of flavonoids , terpenoids , and amino groups in addition to benzene ring agents; which act as stabilizing agents as well as possible aromatic primary amine groups may also be attached with the surface of Ag and TiO 2 NPs. Furthermore, the synthesized AgNPs exhibited strong antibacterial activity against S-aureus and catalytic application over Rose Bengal, Rhodamine B , and 4 nitrophenol dyes as compared to TiO 2 under sunlight (solar irradiation). Overall, Ag and TiO 2 NPs exhibit high potential in the development of antibacterial materials for both Gram-positive as well as Gram-negative bacteria and catalytic material for photocatalytic degradation of a certain type of hazardous dyes or chemicals, thereby paving the way for the treatment and bioremediations. The reason could be high energy and smaller size particles were active in the photo-catalysis and antibacterial performance of AgNPs compared to TiO 2 NPs.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Yuwei Wang,Jingfeng Gao,Wanjun Duan,Wenzhi Zhang,Yifan Zhao,Jie Liu
The inactivation of a gram-negative sulfonamide antibiotic resistant bacteria (ARB) HLS.6 and removal of intracellular antibiotic resistance gene (ARG, sul1 ) and class I integrase gene ( intI1 ) by nanoscale zero-valent iron (nZVI) and sulfide-modified nZVI (S-nZVI) with different S/Fe molar ratios were investigated in this study. The S-nZVI with high sulfur content (S/Fe = 0.05, 0.1, 0.2) was superior to nZVI and the treatment effect was best when S/Fe was 0.1. The ARB (2 × 10 7 CFU/mL) could be completely inactivated by 1.12 g/L of S-nZVI (S/Fe = 0.1) within 15 min, and the removal rates of intracellular sul1 and intI1 reached up to 4.39 log and 4.67 log at 60 min, respectively. Quenching experiments and flow cytometry proved that reactive oxygen species and adsorption were involved in the ARB inactivation and target genes removal. Bacterial death and live staining experiments and transmission electron microscopy showed that the ARB cell structure and intracellular DNA were severely damaged after S-nZVI treatment. This study provided a potential alternative method for controlling the antibiotic resistance in aquatic environment.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
·
2020
·
IF 3.616
Dongqin Lei,Quan Wang,Yue Kong,Yuanwei Chen,Xianglin Luo
It is important to reduce side effects and to explore novel usage for hydrophobic broad-spectrum antibacterial agent triclosan (TCS). In this study, a new amphiphilic copolymer with tertiary amine groups, monomethyl ether poly(ethylene glycol)-b-poly{α-[4-(diethylamino)methyl-1,2,3-triazol]-caprolactone-co-caprolactone} (mPEG-PDCL) was designed and synthesized, and its micelles were applied as carries of TCS to enhance antimicrobial and bacteriostatic action. mPEG-PDCL and its contrastive copolymer mPEG-PCL could form uniform spherical micelles with sizes 50-110 nm . The zeta potential of mPEG-PDCL micelles was positive and changed from 7.00 ± 0.67 mV at pH 7.5 to 24.67 ± 1.23 mV at pH 5.5. Both TCS-loaded micelles displayed quite high drug loading content (approx. 15%) and drug loading efficiency (more than 85%). In comparison with pH 7.4, TCS released faster in acidic environment which was induced by bacteria metabolism. MIC values of both TCS-loaded micelles against S. aureus and E. coli were as low as free TCS. TCS-loaded micelles showed much better antibacterial activity than free TCS, especially, mPEG-PDCL/TCS micelles displayed long bacteriostatic efficacy in 60 h against S. aureus and in 54 h against E. coli . mPEG-PDCL micelles preferred targeting to both S. aureus and E. coli due to positive zeta potential. In in vivo experiment, the purulence of the infected wound almost disappeared for SD rats treated with mPEG-PDCL/TCS micelles. Therefore, mPEG-PDCL micelles may be used as good carriers for antimicrobial agents, and the TCS-loaded micelles possess long antimicrobial/bacteriostatic efficacy.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Reaction Chemistry & Engineering
·
2020
·Vol. 5
·期 8
·1397-1404
·
IF 3.441
Xin Pan,Sihua Wu,Deshan Yao,Lian Liu,Lina Zhang,Zixuan Yao,Yan Pan,Siyuan Chang,Bingfeng Li
5-Hydroxymethyl-2-furancarboxylic acid (HMFCA) is a significant added-value intermediate derivatized from the bio-based platform chemical 5-hydroxymethylfurfuraldehyde (HMF). In the HMFCA biosynthesis process, the catalytic performance of the biocatalyst always decreases due to the presence of HMF toxicity, which is not conducive to achieving high product accumulation. Herein, we successfully obtained a new whole-cell biocatalyst from Pseudomonas aeruginosa PC-1, which was first reported to produce HMFCA from HMF. After optimization, 90.1% yield of HMFCA was attained within 6 h using a 100 mM substrate. Importantly, a much lower cell dosage was needed in the process. In order to achieve higher HMFCA accumulation, a fed-batch strategy was developed by using the growing cells from P. aeruginosa PC-1. Consequently, a total concentration of 721 mM HMFCA was obtained from 800 mM HMF within 58 h after 8 cycles of fed-batch, which is the highest concentration to date. The efficient HMFCA production made P. aeruginosa PC-1 a promising whole-cell biocatalyst for selective, large scale biotransformation of HMF.
✓ 已验证
产品关联
DOI
高影响因子
Polymers
·
2020
·Vol. 12
·期 2
·424
·
IF 3.426
Yicheng Zeng,Yang Liu,Lumin Wang,Hongliang Huang,Xun Zhang,Yongli Liu,Minghua Min,Ying Li
Silver (Ag) nanoparticles were synthesized by a facile route in the presence of oleic acid and n-propylamine. It was shown that the average primary size of the as-synthesized Ag nanoparticles was approximately 10 nm and the surface of as-synthesized Ag nanoparticles was capped with monolayer surfactants with the content of 19.6%. Based on as-synthesized Ag nanoparticles, polyoxymethylene (POM)/Ag nanocomposites were prepared. The influence of Ag nanoparticles on non-isothermal crystallization behavior of POM was investigated by differential scanning calorimetry (DSC). The Jeziorny, Jeziorny-modified Avrami, Ozawa, Liu and Mo, Ziabicki and Kissinger models were applied to analyze the non-isothermal melt crystallization data of POM/Ag nanocomposites. Results of half time (t1/2), crystallization rate parameter (CRP), crystallization rate function (K(T)), kinetic parameter (F(T)), the kinetic crystallizability at unit cooling rate (GZ) and the crystallization activation energy (∆E) were determined. Small amounts of Ag nanoparticles dispersed into POM matrix were shown to act as heterogeneous nuclei, which could enhance the crystallization rate of POM, increase the number of POM spherulites and reduce POM spherulites size. However, the higher loading of Ag nanoparticles were easily aggregated, which restrained POM crystallization to some degree. Furthermore, the POM/Ag nanocomposites showed robust antibacterial activity againstEscherichia coliandStaphylococcus aureus.Keywords:POM;Ag nanoparticles;POM/Ag nanocomposites;non-isothermal crystallization kinetics;heterogeneous nuclei;antibacterial activity
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Colloid and Interface Science Communications
·
2021
·
IF 4.914
Xin-Yu Jiang,Jia-Nan Yan,Yi-Nan Du,Shi-Qi Xu,Hai-Tao Wu
In this communication, the rheological behaviors of hydrolysates from scallop ( Patinopecten yessoensis ) male gonad (SMGHs) combined with eight polysaccharides , including ι -carrageenan, sodium alginate , guar gum , locust-bean gum, pectin, acacia gum, xanthan gum and agar, respectively, were reported. The mixture of SMGHs (5%) and each polysaccharide (0.03–1.25%) was characterized by visual observation and rheological characterization in the concentration ranges where each polysaccharide has visible viscosity and keeps flowing. The addition of ι -carrageenan (0.56%) increased the storage modulus of SMGHs at 0.1 Hz by almost 77-fold, reaching 344.9 Pa. While, when the shear rate was 0.13 s −1 , the mixed-gel viscosity of SMGHs/guar gum and SMGHs/locust-bean gum reached to 137.6 and 129.0 Pa·s, respectively. Moreover, SMGHs have potential application as a gelling agent in the food processing by complexing with a certain polysaccharide.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry B
·
2021
·Vol. 9
·期 41
·8615-8625
·
IF 6.331
Buyun Guo,Rong Fan,Shuwei Shen,Yue Xue,Zhiqiang Zhu,Ronald X. Xu
Accurate delivery of therapeutics to tumor regions and effective sparing of normal tissue structures are important principles for the treatment of widespread metastases or malignant lesions in close proximity to vital organs. However, the currently available drug delivery techniques do not support precise drug release within the identified disease margins. We propose a tailored drug delivery strategy that utilizes a photo-responsive material in combination with tumor margin imaging for automated and tailored release of therapeutics. As a proof of concept, a poly(ethylene oxide)-b-PSPA (PEO-b-PSPA) diblock copolymer is synthesized by spiropyran (SP) polymerization. A photo-responsive membrane (PRM) is formed and irradiated with light sources of different wavelengths. Switching irradiation between ultraviolet light (UV) and green light (Vis) controls the permeability of the PRM in coincidence with the programmed irradiation patterns. The dynamic process of photo-switchable drug permeation through the PRM is modeled and compared with the experimental results. The strategy of tailored drug release is verified using both regular geometric shapes and metastatic cancer images. The therapeutic effect of this tailored drug release strategy is demonstrated in vitro in human breast cancer cells. Our pilot study implies the technical potential of using photo-responsive carriers for image-guided chemotherapy with precisely controlled drug release patterns.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Advanced Composites and Hybrid Materials
·
2021
·Vol. 4
·期 4
·1292-1301
·
IF 5.693
Zhang Pengxiang,Zhang Xihua,Li Bin,Xu Lingan,Dang Feng,Li Bao-Wen
Improving the interfacial impedance matching and attenuation ability of a microwave absorber is an important strategy to obtain excellent microwave absorbing performance. Here, we prepared an ultralight, hierarchical porous single-atom Co–N–C microwave absorber, in which evenly distributed single-atom Co is anchored in a porous N-doped carbon framework by N–Co bond via a facile bio-inspired method. These doped single atoms provide abundant highly active atomic absorption sites on the carbon skeleton, and considerable defects including pyridinic-N, pyrrolic-N, oxidized N, and so forth are introduced into the carbon framework owing to single Co atom doping. These doped single Co atoms and introduced defects act together as strong dipolar/interfacial polarization units, which lead to better impedance matching and a significant increase in attenuation capability of the absorber. The metal Co exists in form of a single atom, benefiting light weight of the absorber. Therefore, an extremely strong reflection loss (RL) value of − 60.9 dB is achieved at a lower filler content of 10 wt% with the absorber thickness of 2.5 mm, and the effective frequency bandwidth covered from 10.4 to 15.1 GHz with a thickness of 2.0 mm at a low filler content of 10 wt%. This research offers a novel route for designing a microwave absorber to improve microwave absorption performance and is expected to a wider range of absorbing materials with different structures. Graphical abstract
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2021
·
IF 10.588
Ying Liu,Jingfeng Gao,Yuwei Wang,Wanjun Duan,Jie Liu,Yi Zhang,Haoran Zhang,Mingyan Zhao
Antibiotic resistant bacteria (ARB) and the antibiotic resistance genes (ARGs) dissemination via plasmid-mediated conjugation have attracted considerable attentions. In this research, sulfidated nanoscale zerovalent iron (S-nZVI)/peroxymonosulfate (PMS) and S-nZVI/peroxydisulfate (PDS) process were investigated to inactivate ARB ( Escherichia coli DH5α with RP4 plasmid, Pseudomonas . HLS-6 contains sul1 and intI1 on genome DNA sequence). S-nZVI/PMS system showed higher efficiency than S-nZVI/PDS on ARB inactivation. Thus, the optimal condition 28 mg/L S-nZVI coupled with 153.7 mg/L (0.5 mM) PMS was applied to remove both intracellular ARGs (iARGs) and ARB. The oxidative damage of ARB cell was systemically studied by cell viability, intracellular Mg 2+ levels, the changes of extracellular and internal structure, integrity of cell walls and membranes and enzymatic activities. S-nZVI/PMS effectively inactivated ARB (~7.32 log) within 15 min. These effects were greatly higher than those achieved individually. Moreover, removal efficiencies of iARGs sul1 , intI1 and tetA were 1.52, 1.79 and 1.56 log, respectively. These results revealed that S-nZVI and PMS have a synergistic effect against ARB and iARGs. The regrowth assays illustrated that the ARB were effectively inactivated. By verifying the inhibitory impacts of S-nZVI/PMS treatment on conjugation transfer, this work highlights a promising alternative technique for inhibiting the horizontal gene transfer.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF DENTISTRY
·
2021
·
IF 4.379
Rui Guo,Wenan Peng,Hongye Yang,Chenmin Yao,Jian Yu,Cui Huang
Objectives This paper aimed to evaluate the influence of resveratrol-doped adhesive on the durability and antibiofilm capability of dentin bonding . Methods Experimental adhesives were prepared by incorporating resveratrol into a universal adhesive at concentrations of 0 (control), 0.1, 1, and 10 mg/mL. The microtensile bond strength, fracture modes, and adhesive–dentin interface nanoleakage were assessed after 24 h of water storage, 10,000 times of thermocycling or 1-month of collagenase ageing. Relevant antibiofilm capability on Streptococcus mutans ( S. mutans ), in situ zymography , degree of conversion, and cytotoxicity of resveratrol-doped adhesives were also determined. Results Irrespective of thermocycled or collagenase ageing, the resveratrol-doped adhesive (1 mg/mL) maintained the bond strength and reduced the nanoleakage expression. Meanwhile, the inhibitory ability on endogenous protease activity and S. mutans biofilm formation with acceptable biocompatibility were obtained. Conclusions This study suggested that the resveratrol-doped adhesive achieved effective improvement on dentin bond durability and secondary caries management. Clinical significance The application of the resveratrol-doped adhesive indicates promising benefits to increase the lifetime of composite restorations.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TEXTILE RESEARCH JOURNAL
·
2019
·
IF 1.613
Lu Wang,Chenmeizi Wang,Qingle Zhang,Jianhua Liu,Xin Xia
As new bio-based sustainable materials, this paper made a comparative study on the phloem and straw of Apocynum venetum. The cellulose nanofibers (CNFs) of Apocynum venetum phloem and straw were prepared by the acid hydrolysis method, and then different parts and proportions of poly (lactic acid) (PLA)/CNF films were prepared via electrospinning, respectively. The results revealed the CNF with longer length and finer diameter network structure can be separated by straw, while the short nanostructure of the rod-like structure can be separated by phloem. It was also shown that the wettability and permeability of PLA improved significantly by adding these two kinds of CNFs, the water contact angle of PLA decreased from 130° to 101° and the permeability was up to 4658 g/(m2•d). As for antibacterial properties, the antibacterial rate of CNF from straw proved slightly better than that from phloem against E.coli, reaching more than 90%. It proved that the CNF from straw showed excellent performance as phloem, providing a novel material for the preparation of CNFs, which can be naturally antibacterial and environment-friendly. The obtained PLA/CNF films could be potentially applied in antibacterial medical dressings.
✓ 已验证
产品关联
DOI
高影响因子
COLLOID AND POLYMER SCIENCE
·
2019
·Vol. 297
·期 5
·705-717
·
IF 1.906
Yan Qing,Liu Lulu,Wang Ting,Wang Henan
An interpenetrating double network hydrogel based on cellulose backbone and poly-dopamine dendritic structure was successfully prepared with the advantages of controlled hydrophobic drug loading, pH-responsive ability, and long-term bacteriostatic property. 13 C-NMR was used to process the structural characterization and explain the mechanism of hydrogel system’s construction. Hydrophobic drug of ciprofloxacin with carbonyl group can evenly carry in the hydrogel system, and the highest loaded ratio of ciprofloxacin was reach to 80.56%. Besides, the swelling property and the controlled drug loading ability of our prepared hydrogel were carefully studied, which showed a close relation with the hydrogel design. Moreover, the in vitro drug release experiments demonstrated that the hydrogel had an obvious pH-responsive release property of ciprofloxacin, and the result of bacteriostatic experiment also showed a long-term bacteriostatic effect on Escherichia coli , which showed potential application on biological and medical fields, including wound treatment.
.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）