OPTICAL FIBER TECHNOLOGY
·
2013
·Vol. 20
·期 1
·28-31
·
IF 1.187
Jiao-Yang Li,Xu-Guang Huang,Wei Xu,Dong-Rui Xiao,Ze-Bing Zhong
A biocompatible fiber-optic pH sensor based on Fresnel reflection technique and a sensing coating is presented. Sodium alginate and polyethylenimine are alternatively deposited on the sensing fiber end to form the sensing coating via a layer-by-layer electrostatic self-assembly technique. An optical switch is added to the measurement system for the convenience of fast calibration. A linear, monotonic and fast response in a large pH range (from pH 5.87 to pH 10.55) is obtained with the resolution of 0.01 pH unit. The sensitivity of the pH sensor is 0.018 R.I.U/pH. It is not influenced by fluctuations of light source.
研究领域:
生物医学工程
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传感技术
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分子生物学
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转化医学
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生物材料
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DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2025
·
IF 3.9
Yuqi Su,Denis Saric,Gabriela Guevara-Carrion,Kaijian Li,Ying Zhang,Maogang He,Jadran Vrabec
Diffusion in electrolyte solutions is critical for applications such as seawater desalination, wastewater treatment and energy storage technologies. However, reliable Fick diffusion coefficient data remain scarce. In this work, the self- and Fick diffusion coefficients of 19 aqueous alkali-halide solutions (LiCl, LiBr, LiI, NaF, NaCl, NaBr, NaI, KF, KCl, KBr, KI, RbF, RbCl, RbBr, RbI, CsF, CsCl, CsBr, CsI) are sampled with molecular simulation techniques at ambient conditions of temperature and pressure for salt concentrations ranging from c = 0.5 to 5 mol L–1. For seven solutions, where experimental Fick diffusion coefficient data were not available (LiI, RbF, RbBr, RbI, CsF, CsBr, CsI), digital holographic interferometry measurements are presented, covering a total of 29 state points. Molecular dynamics simulation accurately predicts the Fick diffusion coefficient when a consistent methodology is applied, combining the sampled Maxwell-Stefan diffusion coefficient with the thermodynamic factor derived from the same force field combination.
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DOI
高影响因子
Frontiers in Pharmacology
·
2024
·
IF 4.4
Xin Qiao,Xiaojuan Cao,Shuang Xu,Cunlin Wang,Rui Guo,Xiaojuan Yao,Qiong Zhang
Background: Dysregulated and excessive inflammatory reactions can lead to tissue damage, which is the underlying cause of most human diseases. Menisoxoisoaporphine A (MA), a novel oxoisoaporphine alkaloid, was obtained from Menispermi Rhizoma, a traditional Chinese medicinal herb used in the treatment of inflammatory conditions in clinical practice. This suggests that MA has very promising potential for the development of anti-inflammatory therapeutics. Hence, this study aims to investigate the anti-inflammatory effects and underlying mechanisms of MA.Method: The anti-inflammatory effects of MA were evaluated in lipopolysaccharide (LPS)-induced mouse macrophage RAW264.7 cells. Its underlying mechanisms were explored through RNA sequencing and Western blotting. The binding modes and interactions sites between MA and phosphodiesterase 4B (PDE4B) were predicted using molecular docking and validated by molecular dynamics simulation.Results: MA treatment significantly reduced LPS-induced morphological changes, inflammatory cytokine relesae, and proinflammatory genes expression in RAW264.7 cells compared to the LPS-induced controls. Transcriptome sequencing analysis suggested that PDE4B might be a key target for MA to exert its therapeutic effect. Mechanismly, MA directly acted on Tyr405 site of PDE4B, thus leading to a sustained elevation of the cyclic adenosine monophosphate (cAMP) levels, which subsequently inactivated NF-κB signaling pathway by phosphorylating protein kinase A (PKA). MA inhibited the NF-κB-mediated inflammatory response depending on PDE4B.Conclusion: MA, a natural and novel compound, exerted anti-inflammatory effects in LPS-induced RAW264.7 macrophage cells. It demonstrated a strong binding ability to the Tyr405 sites of PDE4B, thereby inhibiting NF-κB signaling pathway by regulating the cAMP-PKA axis. Elucidating the interaction between MA and PDE4B holds significant potential for the advancement of innovative therapeutic strategies aimed at inflammatory diseases. By strategically modulating this interaction, it may be feasible to achieve more precise regulation of inflammatory responses, thereby offering promising therapeutic benefits for conditions such as rheumatoid arthritis, asthma, and inflammatory bowel disease.
研究领域:
药理学
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免疫学
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分子生物学
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炎症性疾病
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产品关联
DOI
PubMed
高影响因子
Surfaces and Interfaces
·
2024
·
IF 5.7
Zhihao Liu,Tingting Yang,Yuwen Yan,Yongtao Tang,Jianxin Meng,Fengyu Li
Colorimetry is to determine the component content usually comparing or measuring the “RGB” values, which has the advantages of quick response and visual comparison. However, the widely reported “RGB” models are limited by requiring professional operation such as accurate sampling, insufficient information, cumbersome calculation, etc., which has significantly restricted the promotional application. Inspired by the PAA-PVA gel with excellent absorbing-swelling ability and superior response ability, indefinite volume addition has a significant difference in the swelling phenomenon of PAA-PVA hydrogel, the extent of this enlargement is directly related to the amount of testing sample absorbed, which can be applied to reflect testing sample volume added. In addition, benefited from a comprehensive and precise parameter network, the deep learning (DL) algorithm solves the defects such as ambient light effect and manual extract RGB values of the colorimetric sensing analysis strategy. Considering Fe(II) is an essential element for life science and environmental monitoring, we have developed a self-calibrating colorimetric sensor assisted deep learning strategy for the Fe(II) detection with indefinite volume. It can directly complete the analysis of Fe(II) concentration via captured images, without going through a complicated process similar to the RGB model. Specifically, we integrated the advantages of colorimetric sensing strategy, absorbing-swelling hydrogel, and DL algorithm to develop a phenanthroline (PHEN) indicator doped PAA-PVA colorimetric sensor (PHEN-PAA-PVA). Then, 2,500 colorimetric response images were collected as the training dataset and assessed 2 DL algorithms and 7 machine learning (ML) algorithms. The convolutional neural network (CNN) model exhibited the most efficiency to quantify 1×10 −5 -9×10 −4 mol/L Fe(II), with a limit of detection (LOD) of 3.3×10 −6 mol/L. It provides a promising and blooming in-situ detection approach for Fe(II) analysis, contributes to health management and environment monitoring.
研究领域:
分析化学
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环境科学
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深度学习
·
传感器
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产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2025
·
IF 4.7
Yunkai Sun,Qingqing Song,Meng Cao,Chunhong Tan,Xiao-Feng Wang,Kejie Du,Yuheng Zhang,Yi Ding,Xiaoqiang Xue
Metal-organic complexes, particularly copper complexes, are emerging as promising candidates for anticancer drug due to their versatile redox states. Two copper complexes ( complex1 and complex2 ) have been designed based on the ligands for 1,10-phenanthroline (phen), 4,5-diazofluoren-9-one (DAFO) and 1,4-terephthalic acid (1,4-BDC), and the structures have been determined by X-ray single crystal analysis. The interactions of the complexes with calf thymus DNA (CT-DNA) have been investigated using UV-vis absorption and viscosity measurements. The results indicate that the complex 1 and complex 2 respectively bind to CT-DNA, and the binding mode of the former is in electrostatic binding or groove mode, while that of the latter is in insertion mode. The complex 2 had better activity to break CT-DNA than complex 1 .
研究领域:
无机化学
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生物无机化学
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药物化学
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分子药理学
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核酸化学
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晶体学
·
抗肿瘤药物开发
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产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Yan Gao,Shuhan Lu,Xiongpo Hou,Bin Wang,Zhao Jiang,Yuqi Wang,Tao Fang
Compared to hexagonal 2H-MoS 2 , rhombohedral 3R-MoS 2 exhibits noncentrosymmetric atomic structures and enhanced current density and carrier mobility. Rhombohedral 3R-MoS 2 is considered to possess outstanding electrocatalytic properties comparable to those of 1 T-MoS 2 . However, the preparation of 3R-MoS 2 has been rarely reported owing to its metastable nature and high formation energy. Herein, we perform theoretical calculations to demonstrate that Na adsorption in MoS 2 interlayers can alter the arrangement of adjacent layers. Based on this finding, and assisted by Na 2 SO 4 , a bottom-up synthesis strategy is designed for the in-situ growth of 3R-MoS 2 . In-situ Raman spectroscopy confirms that the electronic configuration of Mo is regulated by the insertion of Na into the MoO 3−x lattice, which is facilitated by high-temperature diffusion, thereby guiding the epitaxial growth of 3R-MoS 2 . As hydrogen evolution reaction catalysts, 3R-MoS 2 exhibits an overpotential of 51.4 mV and a Tafel slope of 35.6 mV/dec. Further analyses indicate that this excellent performance can be attributed to the intrinsic activity of 3R-MoS 2 . Additionally, obtaining a product with perfect crystallinity is fundamental to its electrochemical performance. Importantly, the preparation strategy for pure 3R-MoS 2 developed in this study does not rely on substrates, and the resulting products can be easily transferred and integrated. The proposed method is expected to contribute to the practical application of 3R-MoS 2 in energy storage and also provide a platform to explore stacking sequences and correlations between new phenomena and properties.
研究领域:
材料科学
·
纳米技术
·
电化学
·
催化
·
理论化学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2021
·
IF 5.316
Yunhua Song,Yang Yang,Shudi Mo,Donggang Guo,Lu liu
Construction of heterostructure engineered to modulate the electronic structure and enhance conductivity is an effective approach to enhance the performance of materials. The construction of heterostructure electrocatalysts with efficient catalytic activity by combining 2D nanosheet metal organic frameworks (MOFs) with other earth-rich transition metal oxide materials is a compelling study. Herein, a novel (Fe 2 O 3 ) 0.36 @Ni-MOF heterostructure nanosheets has been synthesized by a rapid one-pot hydrothermal procedure as an efficient OER catalyst. (Fe 2 O 3 ) 0.36 @Ni-MOF exhibited prominent OER property with the overpotential of 230 mV at10 mA cm −2 , a small Tafel slope of 66.7 mV dec −1 and ignorable activity decay after 20 h long-term test at 10 mA cm −2 . The excellent properties of (Fe 2 O 3 ) 0.36 @Ni-MOF nanocomposite could be attribute to the vast amounts of active sites exposed by the nanosheets and ultrasmall size nanoparticles, and the electronic interaction between Fe 2 O 3 and Ni-MOF in the heterostructure. This work presents an attractive tactics for the preparation of heterostructure catalysts with good OER catalytic performance.
研究领域:
材料科学
·
电化学
·
纳米技术
·
催化
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DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Chengfeng Wang,Hongdong Li,Weiping Xiao,Zhenyu Xiao,Guangrui Xu,Dehong Chen,Zexing Wu,Lei Wang
The interaction between metal nanoclusters and the carrier can enhance the electron transfer rate to optimize the hydrogen evolution reaction (HER) performance, but the common synthesis approaches often lead to metal particle agglomeration, and then blocking active sites. Herein, highly-dispersed Pt nanoclusters supported onto molybdenum boride (MoB) is developed through microwave approach with various solvent to regulate the catalytic performance. The synthesized electrocatalyst with the addition of methanol (Pt/MoB-M) exhibits excellent electrocatalytic performance towards HER with low overpotential (13 mV at 10 mA cm −2 ), small Tafel slope (24 mV dec −1 ), and high mass activity (10.06 A/mg Pt at 50 mV). This work presents a novel approach to prepare highly-efficient electrocatalysts for renewable energy-related applications of non-carbon supported low loading of precious metals.
研究领域:
材料科学
·
电化学
·
催化
·
可再生能源
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2024
·
IF 8.1
Sanchuan Liu,Longyun Shen,Yujun Tang,Chengyu Guo,Francesco Ciucci,Zhenghua Tang
Exploring high-efficiency catalyst toward hydrogen evolution reaction (HER) for sustainable hydrogen production is critical for building a forthcoming hydrogen economy. Atomically dispersed catalysts have shown great promises for catalyzing HER yet further fine-tuning the coordination chemical environment to boost the performance is still challenging. Herein, we report the synthesis and electrocatalytic HER application of Ru single atoms dispersed in P, N co-doped porous carbon (Ru SAs@PNC). Spherical aberration corrected scanning transmission electron microscope (AC-STEM) analysis revealed the formation of atomically dispersed Ru single atoms. The as-prepared Ru SAs@PNC catalyst showed excellent HER activity in 1 M KOH, evidenced by a small overpotential of 21 mV @ 10 mA cm −2 and a low Tafel slope of 31 mV dec −1 , both of which are comparable to the Pt/C benchmark catalyst. It also exhibited great durability for long-time operation, as demonstrated by negligible overpotential increase in the 50 h E -t test, and outperformed stability in the accelerated durability test. Such excellent HER performance is mainly attributed to the N, P co-doped chemical coordination environment that differs from most widely reported solely nitrogen-coordinated Ru single atoms.
研究领域:
催化
·
材料科学
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电化学
·
可持续能源
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产品关联
DOI
高影响因子
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
·
2025
·
IF 2.9
Heng Ke,Jixiang Zhang,Wenqi Luo,Yunshan Ding,Liangzhe Chen,Wentao Tang,Youbing Zhang,Jing Ding,Jun Wang,Hong Wang
The fabrication of highly efficient and stable non-noble metal hydrogen evolution reaction (HER) electrocatalysts is of paramount significance for alleviating the energy and environmental crises. Herein, nickel (Ni) nanoparticles anchored on a carbon layer dispersed on carbon materials (Ni/C) are synthesized via a facile one-step thermal treatment. The nanostructure can facilitate mass transfer, expose more active sites and promote hydrogen (H2) gas release. Benefiting from these advantages, Ni/C-0.8 exhibits excellent electrocatalytic HER performance. The overpotential of Ni/C-0.8 is −132 mV at −10 mA cm−2, and its Tafel slope is 117 mV dec−1 in an alkaline solution. Additionally, Ni/C-0.8 exhibits remarkable stability during long-term testing. This work offers a new avenue for designing and fabricating non-noble metal electrocatalysts for the electrocatalytic HER.
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产品关联
DOI
PubMed
高影响因子
POLYMER
·
2025
·
IF 4.5
Yonghao Lv,Hongyan Li,Zhubao Shao,Zhiming Jiang
Cycloaliphatic epoxy resins exhibit excellent dielectric properties but are often harder to be flame retarded. To address this issue, a magnolol-derived active ester DDA was synthesized and employed to prepare flame-retardant cycloaliphatic epoxy resins through the intrinsic incorporation of a phosphaphenanthrene moiety (DOPO). Compared with anhydride MHHPA-cured resins, DDA demonstrated superior char-forming capability and enhanced the compactness of carbon residues. Under equivalent phosphorus loadings, the DDA-cured resin (CFDAP) exhibited a significantly higher limiting oxygen index (LOI) value of 30.2 %, notably surpassing the 26.7 % LOI of the MHHPA-cured counterpart. CFDAP effectively achieved reductions of 44 % in peak heat release rate and 50 % in total heat release during combustion. Importantly, ether bonds instead of ester bonds in the main chain of CFDAP enhanced the thermal stability and tensile strength relative to MHHPA-cured system. The chemical integration of DOPO moiety further improved the dielectric properties of epoxy resins at high frequencies by increasing free volume within the matrix. Collectively, the active ester curing agent DDA enables simultaneous enhancements in flame retardancy, thermal stability, mechanical properties, and dielectric performance of epoxy resins, presenting an efficient strategy for designing advanced electronic packaging materials suitable for high-frequency and high-speed electronic communication.
研究领域:
高分子科学
·
材料工程
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阻燃材料
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介电材料
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电子封装材料
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产品关联
DOI
高影响因子
Nanomaterials
·
2025
·Vol. 15
·期 17
·1356
·
IF 4.3
Jingchao Zhang,Yingping Bu,Jia Hao,Wenjun Zhang,Yao Xiao,Naihui Zhao,Renchun Zhang,Daojun Zhang
Among various H2production methods, splitting water using renewable electricity for H2production is regarded as a promising approach due to its high efficiency and zero carbon emissions. The oxygen evolution reaction (OER) is an important part of splitting water, but also the main bottleneck. The anodic oxygen evolution reaction (OER) for water electrolysis technology involves multi-electron/proton transfer and has sluggish reaction kinetics, which is the key obstacle to the overall efficiency of electrolyzing water. Therefore, it is necessary to develop highly efficient and cheap OER electrocatalysts to drive overall water splitting. Herein, a series of efficient RuO2-Co3O4composites were synthesized via a straightforward three-step process comprising solvothermal synthesis, ion exchange, and calcination. The results indicate that using 10 mg of RuCl3·xH2O and 15 mg of Co-MOF precursor in the second ion exchange step is the most effective way to acquire the Co3O4-RuO2-10 (RCO-10) composite with the largest specific area and the best electrocatalytic performance after the calcination process. The optimal Co3O4-RuO2-10 composite powder catalyst displays low overpotential (η10= 272 mV), a small Tafel slope (64.64 mV dec−1), and good electrochemical stability in alkaline electrolyte; the overall performance of Co3O4-RuO2-10 surpasses that of many related cobalt-based oxide catalysts. Furthermore, through integration with a carbon cloth substrate, Co3O4-RuO2-10/CC can be directly used as a self-supporting electrode with high stability. This work presents a straightforward method to design Co3O4-RuO2composite array catalysts for high-performance electrocatalytic OER performance.
研究领域:
电化学
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材料科学
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催化
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可再生能源
·
纳米材料
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）