CHEMOSPHERE
·
2019
·
IF 5.108
Huizhong Chi,Xu He,Jianqiao Zhang,Jun Ma
Degradation of naproxen, bisphenol S and ibuprofen in a hydroxylamine enhanced zero-valent copper (Cu 0 ) catalyzed peroxymonosulfate system was investigated for the first time. We found that hydroxylamine addition accelerated the reduction of Cu 2+ to Cu + as well as the corrosion of Cu 0 , and environmental friendly gas nitrogen was the main product of hydroxylamine. Additionally, hydroxyl radical and sulfate radical were identified to be the dominant reaction species by competitive experiments. The degradation of naproxen, bisphenol S and ibuprofen kept highly efficient in the pH range of 3.0–7.0 in Cu 0 /hydroxylamine/peroxymonosulfate process, with their degradation products identified by HPLC-MS, which showed that Cu 0 /hydroxylamine/peroxymonosulfate system could be an alternative to remove non-steroidal antiinflammatory drugs or plasticizers in wastewater. Furthermore, the effects of Cu 0 , hydroxylamine and peroxymonosulfate dosage were studied and optimized by a BBD based response surface model. This study provided a method to solve the disadvantages of Cu 0 /peroxymonosulfate systems, and gave a promising method to enhance the efficiencies of ZVMs activated system such as iron, cobalt and copper.
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SOLID STATE SCIENCES
·
2019
·
IF 2.155
Jianxun Zhao,Xiangjun Zhou,Yalan Guo,Zhongmin Su,Heng Liu,Wanqiang Liu,Shang Gao
Co 0.9 Cu 0.1 Si alloy was fabricated via mechanical alloying technique. Different amount of palladium was doped into the Co 0.9 Cu 0.1 Si alloy by ball milling. The composite alloy combined the excellent electrocatalysis activity of Pd, exhibiting preferable electrochemical performance than the original alloy. The Co 0.9 Cu 0.1 Si + 5 wt% Pd composite showed a C max of 559.2 mAh/g, significantly higher than that for Co 0.9 Cu 0.1 Si (502.1 mAh/g). The cycle stability was also enhanced after Pd loading. Moreover, the effect of ball milling time on electrochemical performance for the composite alloy was also investigated. 5 wt% Pd was mixed with the Co 0.9 Cu 0.1 Si alloy at different ball milling time (0.5 h, 1 h, 2 h, 3 h and 5 h). The optimal discharge capacity, capacity retention and high-rate dischargeability were obtained under the ball milling time of 2 h. The studies on electrochemical reaction kinetics demonstrated that the addition of Pd could accelerate the charge-transfer, thus enhancing the electrochemical activity and reaction kinetics of the alloy. The results indicated that Pd loading was an effective way in enhancing the electrochemical performance of Co 0.9 Cu 0.1 Si alloy.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2019
·
IF 4.784
Cihui Tian,Sajid Asghar,Ziyi Hu,Yue Qiu,Jingwei Zhang,Feng Shao,Yanyu Xiao
The gliomas treatment is challenging due to the limits imposed by blood-brain barrier to the distribution of the drugs in the brain. Therefore, we designed a brain glioma targeting redox-sensitive hyaluronic acid (HA)-ss-curcumin (CUR) micelles . HA was conjugated to CUR through a disulfide bond , which could form micelles independently in aqueous solution. And we further increased the drug loading by loading free CUR. Brain penetration was achieved with Tween 80, whereas glioma-targeting was inclined by CD44-mediated endocytosis . Compared to the disulfide-free group, the redox-sensitive micelles exhibited rapid in vitro drug release under high glutathione conditions, significantly enhanced cell apoptosis and cellular uptake in G422 glioma cells. Redox-sensitive micelles displayed about 4.70-fold higher area under the curve in rats after intravenous injection in comparison to the free CUR and effectively accumulated in the brain. These findings suggest that redox-sensitive micelles could be a promising candidate to achieve brain targeted CUR delivery.
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CHEMICAL PAPERS
·
2019
·Vol. 74
·期 2
·485-497
·
IF 1.246
Quan Cong,Liu Jiayu,Sun Wei,Cheng Xinjian
It is extremely necessary to detect heavy metals sensitively and selectively, especially the ions that will cause great harm to humans and the environment. This work deals with two fluorescent chemosensors and their outstanding role when detecting Zn 2+ and Cd 2+ ions. First, a small molecular chemosensor (TPB) has been designed and synthesized via Suzuki reaction using one part of benzene-1,3,5-triyltriboronic acid and three parts of 2-bromo-1, 10-phenanthroline as starting materials. And then, its corresponding macromolecular fluorescent chemosensor (PTPB) was synthesized. The infrared spectra, mass spectrometry (MS), and 1 H-NMR were used to study the structures of TPB and PTPB. From what has been studied, the TPB and PTPB were stable in a relative wide pH range. As soon as the Cd 2+ and Zn 2+ ions added, fluorescence of the two sensors TPB and PTPB was changed obviously. In addition, PTPB was found have better performance to both Cd 2+ and Zn 2+ than TPB through the ‘‘molecular wire’’ mechanism. Job’s plots were also be tested, showing that the combination ratio of TPB and PTPB to Cd 2+ and Zn 2+ were both 3:1 (ion/sensor). In addition, the minimum detection limits of the macromolecular chemosensor PTPB for Cd 2+ and Zn 2+ reached 0.424 μM and 1.27 μM, respectively.
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CHEMISTRY-A EUROPEAN JOURNAL
·
2019
·Vol. 25
·期 49
·11486-11493
·
IF 5.16
Xinyi Wang,Xijun Xu,Jun Liu,Zhengbo Liu,Jiadong Shen,Fangkun Li,Renzong Hu,Lichun Yang,Liuzhang Ouyang,Min Zhu
Graphical Nanocomposite anodes : Uniform peapod-like Cu 3 Ge/Ge@C composites are fabricated successfully through a facile dopamine-coating and annealing route (see figure). Owing to the homogeneous carbon encapsulation and the addition of the inactive alloying phase Cu 3 Ge, this Ge-based anode exhibits an excellent high specific capacity, outstanding cycle stability, and excellent rate performance for LIBs. As anode materials for high-performance Li-ion batteries, peapod-like Ge-based composites, including Ge, a Li-inactive conducting Cu 3 Ge, and a porous carbon matrix are synthesized simply by annealing CuGeO 3 @dopamine in a H 2 /Ar atmosphere. The introduction of the carbon layer and inactive alloying phase Cu 3 Ge not only enhances the electrical conductivity of the Ge anode, but also reduces the volume change of Ge during the cell cycle as a buffer. In particular, the anode of this peapod-like Cu 3 Ge/Ge@C shows an excellent long cycle life as well as outstanding capacity performance, with a discharge specific capacity up to 934 mA h g −1 after 500 cycles.
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MATERIALS AND CORROSION-WERKSTOFFE UND KORROSION
·
2019
·Vol. 70
·期 11
·1964-1976
·
IF 1.458
Jin Li,Daquan Zhang,Kai Zhang,Lixin Gao,Cheng Shi,Donghui Chen,Manhong Huang
The triazole inhibitor of 1-(p-tolylthio)-1H-1,2,3-triazole-4-carboxylic acid (TTC) was synthesized via the Cu(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition reaction. The self-assembling method was performed to fabricate the self-assembled film of TTC on the copper surface. The electrochemical measurement results indicate that the TTC film can efficiently protect the copper from corrosion in high concentrated industrial cooling water. The protection efficiency of TTC film for copper is 92.2%. Surface characterizations imply that the copper with TTC film after corrosion is covered with multiple protective layers. It probably contains Cu(I) and Cu(II) complexes mixed with nitrogenous compound, Cl − and SO 4 2− . The result of quantum chemical calculation shows that the superior performance of TTC film is related to the adsorption of TTC molecules on copper surface horizontally. This kind of adsorption is mainly achieved via the adsorption centers of triazole ring and O atoms in TTC molecule.
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Molecular Medicine Reports
·
2019
·Vol. 20
·期 1
·771-778
·
IF 1.851
Yanyan Wang,Huaqiao Tang,Min Xu,Jie Luo,Ling Zhao,Fei Shi,Gang Ye,Cheng Lv,Yinglun Li
The aim of the present study was to evaluate the long‑term effect of copper nanoparticles (CuNPs) on cytochrome P450 (CYP450) enzymes in the rat brain. Rats were repeatedly gavaged with different forms of copper sources for 28 days, and the levels of oxidative stress and CYP450 mRNA and protein expression in the rat brain were subsequently analyzed. The results demonstrated that a high dose of CuNPs (200 mg/kg) induced severe oxidative stress in the rat brain along with a decrease in the levels of total superoxide dismutase and glutathione, and an increase in hydroxyl radicals and malondialdehyde. A medium dose of CuNPs reduced CYP450 2C11 and CYP450 3A1 protein expression in the rat brain, whereas high doses of CuNPs resulted in decreased expression of most CYP450 enzyme proteins, and inhibition of pregnane X receptor and constitutive androstane receptor expression. The results suggested that CuNPs may inhibit CYP450 enzyme expression by increasing the levels of oxidative stress and decreasing the expression of nuclear receptors in the rat brain, which affects the metabolism of drugs and endogenous hormones in the brain.
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Analytical Methods
·
2019
·Vol. 11
·期 34
·4382-4389
·
IF 2.378
Fanglin Ming,Jingzhou Hou,Danqun Huo,Jun Zhou,Mei Yang,Caihong Shen,Suyi Zhang,Changjun Hou
A luminescent amino-functionalized metal–organic framework (Cu–MOFs) was synthesized from 2-aminoterephthalic acid and Cu(II) ions by a solvothermal method. Cu–MOFs displayed blue fluorescence with a peak at 430 nm under 330 nm excitation. Its structure was characterized by FTIR, TEM, XRD, and XPS. The fluorescence of the Cu–MOFs was quenched by Fe3+ in aqueous solutions. The limit of detection was 0.5 μM, and the linear working range extended from 2 μM to 35 μM. Additionally, a good logarithmic relationship between relative fluorescence intensity (F/F0) and Fe3+ concentrations ranging from 2 to 180 μM was obtained with a detection limit of 1.56 μM (R2 = 0.9975). No clear interference was observed when challenged with a wide variety of cations and anions. The recoveries from spiked real water samples were in the range of 91.7–107.7%, and the detection results were consistent with inductively coupled plasma mass spectrometry (ICP-MS) results. Therefore, the fluorescent sensor has great potential in environmental monitoring.
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CHEMOSPHERE
·
2019
·
IF 5.108
Huizhong Chi,Zeyu Wang,Xu He,Jianqiao Zhang,Da Wang,Jun Ma
Organic degradation by zero-valent metal (ZVM)-activated peroxymonosulfate (PMS) systems has drawn great attention in water treatment . Among various types of ZVM, zero-valent copper (ZVC) showed greatest activating capacity. However, the disadvantages of the released Cu 2+ limit the practical utilization of ZVC. In this study, the activation capacity of four normal-sized copper catalysts, namely, copper sheet, graphene-copper sheet, copper foam, and graphene-copper foam, for PMS was investigated using Naproxen (NPX) as the probe compound. Results showed that the degradation efficiency of NPX increased by 10%, while the release of Cu 2+ decreased by 30% by coating the copper with graphene. Stability tests showed that all of the four catalysts exhibited considerable stability in PMS activation . Furthermore, we found for the first time that the hydroxyl radical was the dominant species in the degradation of NPX rather than the sulfate radical, which was proved by ESR and radical scavenging experiments. Finally, six intermediates were identified by HPLC-MS/MS, and the degradation pathways were proposed. This study confirmed the feasibility of graphene coating on metals to achieve the enhancement of PMS activation.
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Nano-Micro Letters
·
2020
·Vol. 12
·期 1
·1-13
·
IF 12.264
Pan Zhengbin,Han Ershuan,Zheng Jingui,Lu Jing,Wang Xiaolin,Yin Yanbin,Waterhouse Geoffrey I. N.,Wang Xiuguo,Li Peiqiang
Flower-like CeO 2 nanoparticles enhance the performance of CuO nanoparticle/Cu.
The system benefits from the heterojunction between p-type CuO and n-type CeO 2 .
The selective reduction of CO 2 to methanol on the target catalyst is studied.
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ELECTROCHIMICA ACTA
·
2020
·
IF 6.215
Chenhuinan Wei,Xiao Zou,Qiming Liu,Shuxian Li,Chenxia Kang,Wei Xiang
CuS nanosheets modified Cu 2 O/CuO nanowire arrays (NWAs) were successfully fabricated on Cu foil by in-situ growth and successive ionic layer adsorption and reaction (SILAR) methods without binders. The three-dimensional Cu 2 O/CuO NWAs not only showed strong binding force with current collector but also provided abundant surface area to support CuS nanosheets. Different morphologies of CuS were obtained by varying the Cu(NO 3 ) 2 and Na 2 S concentrations and the SILAR cycle. When these step-wise prepared products were employed for non-enzymatic glucose sensing, the amperometric response of the optimized CuS/Cu 2 O/CuO/Cu electrode was approximately twice of that of Cu 2 O/CuO/Cu electrode. The result is attributed to the modification of CuS nanosheets with suitable amount which increases the active surface area of the electrode. This designed electrode presents an ultrahigh sensitivity of 4262 μA mM −1 cm −2 in the range from 0.002 to 4.096 mM, as well as the excellent selectivity, reproducibility and stability. Moreover, due to the facile preparation and the low cost of Cu based sensors, the CuS/Cu 2 O/CuO/Cu electrode will be one kind of promising materials for constructing practical non-enzymatic glucose sensors.
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Food Packaging and Shelf Life
·
2019
·
IF 3.63
Zi-Wei Jiang,Wen-Wen Yu,Yan Li,Lei Zhu,Chang-Ying Hu
Nanocopper with different concentrations was introduced to homopolymer polypropylene (PP-H) matrix to prepare nanocopper/PP-H composite film. Film appearance, mechanical and thermal properties were investigated. Migration test to 3% acetic acid (w/v) food simulant, film antibacterial ability and human hepatotoxicity were conducted to further evaluate film safeness. FTIR results suggest that nanocopper particles were physically dispersed in PP-H matrix and the addition of nanocopper could significantly improve thermal and mechanical properties of composite films, ensuring its potential utilization for food packaging. Also, the composite film showed great antibacterial ability including Escherichia coli , Staphylococcus aureus , Shigella castellani and Bacillus subtilis . At 70 ℃, when the initial concentration of added nanocopper reached 1% (w/w) or higher, the concentration of copper migrated from film to acetic food simulant would reach to 4.5 μg/g and would start damaging L-02 cells. This study provides important information for the potential utilization of nanocopper in food packaging films.
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