APPLIED CATALYSIS A-GENERAL
·
2013
·
IF 3.41
Bing Liu,Zehui Zhang,Kangle Lv,Kejian Deng,Hongmin Duan
Magnetic Fe 3 O 4 supported Mn 3 O 4 nanoparticles (Fe 3 O 4 /Mn 3 O 4 ) were prepared by the solvent thermal method, and its structure was characterized by XRD, XPS, TEM, and FT-IR technologies. The resulting Fe 3 O 4 /Mn 3 O 4 nanoparticles could be used as an excellent heterogeneous catalyst for the aerobic oxidation of the biomass-derived model molecule 5-hydroxymethylfurfural into 2,5-diformylfuran (DFF) under benign reaction conditions. Some important reaction parameters such as reaction temperature, catalyst amount, solvent, oxidant, and oxygen pressure were explored and high DFF yield of 82.1% with HMF conversion of 100% were obtained in DMF under optimal reaction conditions. More importantly, the catalyst could be readily separated from the reaction mixture by a permanent magnet, and recycled up to 6 times without the significant loss of its catalytic activity.
研究领域:
化学工程
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材料科学
·
可再生能源
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DOI
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2025
·
IF 8
Duoduo Zhang,Kunying Chen,Yongkang Yu,Ruting Feng,Steve W. Cui,Xingtao Zhou,Shaoping Nie
Metabolites of dietary fibers which consist of non-digestible carbohydrates (usually as plant-based polysaccharides) exert many benefits on gastrointestinal health. Previous studies proved that polysaccharides can change intestinal metabolic pathways, increase metabolite levels and alleviate intestinal inflammation. Our previous studies have shown that polysaccharide from Aloe vera gel (AGP) alleviated intestinal barrier dysfunction. However, whether intestinal protective function of AGP was related to metabolites need further exploration. Therefore, the effects of AGP on intestinal metabolites and the relevant mechanisms for subsequent mitigation of intestinal damage was investigated in this work. Metabolomics analysis results showed that AGP promoted tryptophan metabolism to 5-hydroxytryptamine (5-HT). Intriguingly, antibiotics treatment decreased the expression of tryptophan hydroxylase 1 (TPH1) in the intestinal epithelium of mice, and TPH1 inhibitor (PCPA) down-regulated 5-HT level in colonic contents, proving that AGP up-regulated TPH1 expression in the intestinal epithelium by restoring intestinal microbiota homeostasis, thus promoted the intestinal tryptophan metabolism to 5-HT. Combination of bioinformatics analysis of RNA-sequencing (RNA-Seq) in mice colon and the reported relationship among “5-HT, Htr4 (one of the 5-HT receptors), Kit + goblet cells, canonical Wnt pathway and intestinal stem cells (ISCs)” guided the confirmation of related mechanism in intestinal organoids (IOs) that 5-HT regulated ISCs function and intestinal barrier via Htr4-Kit-Wnt3 axis. Overall, AGP promoted 5-HT production to alleviate intestinal injury. This study revealed the effects of polysaccharides on intestinal health, which was critical and may provide new insights for the reasonable selection of dietary fiber to prevent intestinal inflammation and maintain intestinal function.
研究领域:
胃肠病学
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营养学
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分子生物学
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产品关联
DOI
PubMed
高影响因子
BIOMASS & BIOENERGY
·
2025
·
IF 5.8
Junxiang Wang,Xu Wang,Xiaoyan Liu,Yanfei Feng,Yukun Wan,Hui Yang
Electrocatalytic 5-hydroxymethylfurfural oxidation reaction (HMFOR) to produce 2,5-furanedicarboxylic acid (FDCA) offers a promising strategy to produce high value chemicals. Herein, CuO(S-ER-1.5) with excellent catalytic performance was prepared by anodic oxidation, sulfidation and electrochemical reconstruction on the substrate of copper foam. The experimental results of catalytic performance showed that CuO(S-ER-1.5) can catalyze HMFOR with a high current density (200 mA cm −2 ) at a low potential (1.48 V vs RHE) and exhibit outstanding stability. The open-circuit potential time test displayed that more HMF molecules were adsorbed in the Helmholtz layer of CuO(S-ER-1.5), which proved that the CuO(S-ER-1.5) could improve the kinetic adsorption of HMF. The electrochemical impedance spectroscopy further showed that CuO(S-ER-1.5) had faster reaction kinetics than Cu(OH) 2 precursor. The product analysis showed that CuO(S-ER-1.5) electrocatalytic HMFOR followed the DFF path, and the catalytic mechanism was explored by the three-step rate deconvolution procedure. It was found that CuO(S-ER-1.5) electrocatalytic HMFOR was dominated by direct oxidation reaction. This work provides a valuable guidance for the synthesis of value-added chemicals FDCA by electrocatalytic HMFOR.
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产品关联
DOI
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2021
·
IF 5.645
Ping Zhang,Cong Zhang,Tiancheng Jiang,Md. Yousuf Hossain,Wenju Zhu,Md. Nahid Pervez,Md. Ikram Ul Hoque,Iusuf Khan,Xuejun Long,Yingjie Cai
The traditional grass cloth, which has a long history in China, is primarily constructed of raw ramie yarns. In this study, the dye adsorption of three reactive dyes (Reactive Red 2, Reactive Blue 194, and Reactive Orange 5) onto raw ramie yarns indicated that the high-temperature type of reactive dye was more suitable for dyeing raw ramie yarn. The adsorption kinetics for the sorption of Reactive Orange 5 onto raw and degummed ramie yarns was studied by applying pseudo-first-order and pseudo-second-order kinetics and the intraparticle diffusion model. The kinetics study revealed that adsorption primarily followed the pseudo-second-order model in the case of both yarns, and the adsorptions were spontaneous and exothermic. The adsorption isotherms were studied by applying Langmuir and Freundlich isotherm models and found that the Freundlich isotherm model was better fitted. The dyeing performance of Reactive Orange 5 on raw ramie fiber was investigated and compared with that of the degummed ramie yarn. The dyed fiber surface and cross-section were investigated using an optical microscope to understand the structural characteristics. The influences of different dyeing conditions and soap washing on gummy substance removal were also investigated. The tensile strength, stiffness, and colorfastness were also evaluated after raw ramie yarn washing. After the dyeing and soaping processes, gummy substances in the fiber were removed, and notably, they did not affect the water absorbency, tensile strength, and stiffness of ramie yarn.
研究领域:
纺织科学
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材料科学
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染料化学
✓ 已验证
DOI
高影响因子
Polymers
·
2025
·Vol. 17
·期 10
·1413
·
IF 4.9
Huimin Gao,Wei Mao,Pize Xiao,Chutong Ling,Zhiming Wu,Jinghong Zhou
5-Hydroxymethylfurfural (HMF) is a versatile carbohydrate-derived platform chemical that has been used for the synthesis of a number of commercially valuable compounds. In this study, several chromium (Cr)-doped, biomass-derived hydrochar catalysts were synthesized via the one-pot method using starch, eucalyptus wood, and bagasse as carbon sources. Then, the performance of these synthesized materials for the catalytic conversion of glucose into HMF was evaluated by, primarily, the yield of HMF. The synergistic interactions between the Cr salt and the different biomass components were investigated, along with their effects on the catalytic efficiency. The differences in the catalytic activity of the synthesized materials were analyzed through structural characterization, as well as assessments of the acid density and strength. Among the catalysts, Cr5BHC180derived from bagasse presented the highest activity, achieving an HMF yield of 64.5% in an aqueous solvent system of dimethyl sulfoxide (DMSO) and saturated sodium chloride (NaCl) at 170 °C after 5 h. After four cycles, the HMF yield of Cr5BHC180decreased to 38.7%. Characterization techniques such as N2adsorption–desorption and Py-FTIR suggested that such a decline in the HMF yield is due to pore blockage and acid site coverage by humic by-products, as demonstrated by the fact that regeneration by calcination at 300 °C restored the HMF yield to 50.5%.
研究领域:
化学工程
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材料科学
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环境科学
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产品关联
DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
·
2021
·
IF 6.707
Wenguang Zhao,Zexing Huang,Liu Yang,Xianxiang Liu,Hongye Xie,Zixuan Liu
The hydrogenation of furan derivatives is of great scientific and strategic significance because the molecular diversity of the hydrogenation products ensures the efficient utilization of biomass resources. In this study, an inexpensive and magnetically separable bimetallic catalyst (Ni x Co y ) was synthesised via solid-phase grinding. The catalyst exhibited efficient catalytic activity towards the hydrogenation of 5-hydroxymethylfurfural (HMF) into 2,5-bis(hydroxymethyl)furan (BHMF) and 2,5-dimethylfuran (DMF) at a low reaction temperature and H 2 pressure. Further, the 93.1% and 80.1% selectivities of BHMF and DMF with a full conversion of HMF were obtained under the optimal conditions by controlling the temperature, respectively. Furthermore, the as-prepared catalysts were characterized via the thermogravimetry–derivative thermogravimetry (TG-DTG), X-ray photoelectron spectroscopy (XPS), inductively coupled plasma atomic emission spectroscopy (ICP-AES), X-ray diffraction (XRD), Fourier-transform infrared (FT-IR), and N 2 adsorption–desorption isotherm techniques. Additionally, the synergistic catalytic effect of the hydrogenation sites in the Ni and Co metals, as well as the Lewis acid sites in NiO and CoO promoted the conversion of HMF into BHMF and DMF. Thereafter, the possible synergistic catalytic mechanism was proposed based on the characterization of the catalyst and the experimental results.
研究领域:
化学工程
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可再生能源
·
催化科学
✓ 已验证
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2024
·
IF 3.8
Dezhu Zhang,Su Fan,Kenan Xu,Haotian Liu,Nana Chang,Yijie Wang,Yixing Wang,Kang Huang,Zhi Xu
Vanadium flow battery (VFB) shows great potential in balancing the volatility of renewable energy. In this work, we investigated, for the first time, the various properties of crystalline ZSM-5 membranes prepared through the organic template-free gel strategy in VFB. The subnano windows (∼0.55 nm) of ZSM-5 zeolite provided selective transport paths for protons (∼0.27 nm) and blocked the vanadium (>0.6 nm) migration through pore repulsion effect. The zeolite membranes exhibited a very low vanadium penetration rate (0.05 mmol L–1 h–1), achieving a Coulombic efficiency (CE) of 96.1%, a voltage efficiency of 78.3%, and an energy efficiency of 75.3% at the current density of 40 mA cm–2. Notably, ZSM-5 prepared using the template-free strategy eliminates the need for a high-temperature calcination step, and the membrane has a lower defect density and exhibits a higher CE. The self-discharge time of the ZSM-5 zeolite membrane increased up to 78 h. Furthermore, the charge–discharge performance kept stable more than 300 cycles at 60 mA cm–2.
研究领域:
材料科学
·
能源存储
✓ 已验证
产品关联
DOI
高影响因子
ChemCatChem
·
2021
·Vol. 13
·期 16
·3601-3610
·
IF 5.686
Bing Xu,Minghui Tan,Xuemei Wu,Hailun Geng,Shengying Zhao,Jie Yao,Qingxiang Ma,Guohui Yang,Noritatsu Tsubaki,Yisheng Tan
Graphical Catalytic propane aromatization : Post-introducing Cr species to Ga/Z5 catalyst had the maximum dehydrogenated active Cr 3+ species. Propane was effectively converted, and more light alkenes from propane dehydrogenation were converted into BTX on 2Cr/GaZ5 catalyst. Active Cr 3+ species and strong interaction between Ga species and ZSM-5 zeolite on 2Cr/GaZ5 catalyst accelerated the dehydrogenation step in propane aromatization. Accelerating propane dehydrogenation in propane aromatization is vital because it is the first and rate control step. In this study, we introduced Cr to Ga/ZSM-5 by tuning its impregnation sequence and amount, which was expected to accelerate the dehydrogenation step and improve aromatization performance. The impregnation sequence of Cr on catalyst not only affected the interaction between Ga and ZSM-5, but also tuned the amount of dehydrogenation active species Cr 3+ . Due to the plenty of Cr 3+ species and strong interaction between Ga species and ZSM-5, 2Cr/GaZ5 catalyst accelerated the dehydrogenation step and improved the aromatization process. More light hydrocarbons were preferred to be produced and were further converted into BTX on 2Cr/GaZ5 catalyst. Excessive Cr on catalyst caused the formation of Cr 2 O 3 particles with worse dispersion. The aggregated Cr 2 O 3 decreased the strong acidity of catalyst, which could not further promote propane conversion and decreased the aromatization ability of catalyst.
研究领域:
催化化学
·
材料科学
✓ 已验证
DOI
高影响因子
GREEN CHEMISTRY
·
2012
·Vol. 14
·期 9
·2506-2512
·
IF 6.32
Jianjian Wang,Jiawen Ren,Xiaohui Liu,Jinxu Xi,Qineng Xia,Yanhong Zu,Guanzhong Lu,Yanqin Wang
5-Hydroxymethylfurfural (HMF) is a very important intermediate in the fine chemical industry. This study aims to investigate the direct conversion of glucose or glucose-based carbohydrates, such as sucrose, cellobiose, inulin, starch and cellulose, to HMF by using a Sn-Mont catalyst. With the use of this catalyst, a HMF yield of 53.5% was achieved from glucose in a mono-phase medium of tetrahydrofuran (THF)/dimethylsulfoxide (DMSO) at 160 °C for 3 h. The success of one-step conversion of glucose to HMF is attributed to the Sn-Mont catalyst containing two types of acid sites, Lewis acid and Brønsted acid sites. The former one plays a crucial role in the isomerization of glucose to fructose and the latter one is active in the dehydration of generated fructose to HMF. Furthermore, Sn-Mont catalyst also demonstrated excellent activity in the conversion of disaccharides and polysaccharides and as high as 39.1% HMF was directly obtained from cellulose in a THF/H2O–NaCl bi-phasic system.
研究领域:
化学工程
·
催化科学
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产品关联
DOI
高影响因子
Journal of Energy Chemistry
·
2017
·
IF 2.594
Xiaoyu Wang,Wei Chen,Zheng Li,Xianhai Zeng,Xing Tang,Yong Sun,Tingzhou Lei,Lu Lin
In this study we report a new reaction pathway in which the hydroxyl and the aldehyde groups of 5-hydroxymethyl furfural were aminated respectively. Hydroxyl group was aminated via Ritter reaction followed by direct reductive amination of aldehyde group. For the Ritter reaction of 5-hydroxymethyl furfural, mixture of trifluoromethane sulfonic acid and phosphoric anhydride showed good performance and the intermediate N -acyl-5-aminomethyl furfural with the highest yield of 89.1 wt% was obtained. Optimization of direct reductive amination of 2,5-bis(aminomethyl) furan was conducted and a yield of 45.7 wt% was achieved. This study presents a simple way for preparing bis(amino)furans from renewable biomass based 5-hydroxymethyl furfural, which enriches the biorefinery concept from biomass.
研究领域:
有机化学
·
生物质能
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产品关联
DOI
高影响因子
Frontiers in Chemistry
·
2019
·
IF 3.782
Li Renna,Chong Shijia,Altaf Naveed,Gao Yanshan,Louis Benoit,Wang Qiang
In this research, we investigated the hydrophobicity and dynamic adsorption-desorption behaviors of volatile organic compounds (VOCs) by applying different optimized coating dosage (25, 50, and 75%) on designed novel ZSM-5/MCM-41 and ZSM-5/Silicalite-1 hierarchical composites. The relatively large specific surface area and pore volume of adsorbents ZSM-5/MCM-41 and ZSM-5/Silicalite-1 composites with excellent stability were affirmed by ex-situ XRD, FTIR, BET, SEM, and water contact angle analyses. Regarding, toluene adsorption-desorption investigation, ZSM-5/MCM-41 composite lead a longer stable toluene breakthrough time no matter under dry or 50% humid conditions. However, under different loading dosage condition, the breakthrough time of 75% coating ratio was the longest, which was 1.6 times as long as that of pure ZSM-5 under wet adsorption. Meanwhile, the complete elimination of toluene for ZSM-5/MCM-41-75% was done by largest desorption peak area and the lowest desorption temperature of 101.9°C, while, the largest contact angle of ZSM-5/MCM-41-75% was 17.0° higher than pure ZSM-5 zeolite. Therefore, we believe that the present hydrophobic sorbent will provide new insight with great research potential for removing low concentration of VOCs at industrial scale.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
BIOCHEMICAL PHARMACOLOGY
·
2025
·
IF 5.6
Dapeng Lu,Lin Ma,Qingyue Zhang,Chengzhong Xing,Yanke Li
5-Fluorouracil (5-FU) is an effective drug in the treatment of colorectal cancer (CRC); however, the development of acquired resistance to 5-FU poses a great challenge in clinical practice. Through the analysis of public datasets, we found that reduced 3-Hydroxybutyrate Dehydrogenase 2 (BDH2) expression in CRC tissues predicted poor survival in CRC patients. Low expression of BDH2 in clinical CRC tissue samples predicted a higher degree of malignancy. In addition, public dataset analysis showed that GLI Pathogenesis Related 1 (GLIPR1) expression was elevated in CRC patients following 5-FU treatment, contrasting with the expression pattern of BDH2. We reported that in 5-FU-resistant CRC cell lines (LOVO/5-FU and HCT15/5-FU), BDH2 was downregulated, while the expression of GLIPR1 was increased. To explore the regulatory relationship between BDH2 and GLIPR1 in 5-FU resistance, BDH2 and GLIPR1 overexpression plasmid vectors were constructed to transfect 5-FU resistant CRC cell lines. BDH2 led to enhanced 5-FU sensitivity in 5-FU-resistant CRC cell lines and inhibited the malignant behavior of CRC-resistant cells in vitro . In nude mice with subcutaneous tumors and intraperitoneal injections of 5-FU, tumor tissues formed by BDH2-overexpressing cells exhibited slower growth and increased apoptosis. Mechanistically, the upregulation of BDH2 increases GLIPR1 promoter methylation, mediated by DNA methyltransferases, thereby inhibiting GLIPR1 expression. High expression of GLIPR1 reduces 5-FU sensitivity in 5-FU-resistant CRC cell lines, which abolished the impact of BDH2 expression. These results suggest that BDH2 inhibits GLIPR1 expression by increasing GLIPR1 promoter methylation, thereby enhancing 5-FU sensitivity of 5-FU-resistant CRC cell lines and inhibiting CRC progression.
研究领域:
肿瘤学
·
分子生物学
·
药理学
·
表观遗传学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）