REACTIVE & FUNCTIONAL POLYMERS
·
2025
·
IF 5.1
Wenxing Yuan,Rende Qin,Yuming Wang,Yongjie Yuan,Hailiang Zhang
Antibacterial nylon 6 exhibits excellent antibacterial properties, as well as good mechanical performance, wear resistance, and dyeing characteristics, making it widely applicable in various fields such as automotive, medical, apparel, and personal care industries, including medical sutures, food packaging films, and automotive interior materials. However, most of the reported antibacterial nylon 6 is prepared by doping antibacterial agents. Developing a simple strategy to synthesize intrinsically antimicrobial nylon 6 with superior antibacterial performance is of great significance, but also presents challenges. In this study, we propose a strategy for preparing intrinsically antimicrobial nylon 6 through a capping strategy. 2-Methyl-4-(trifluoromethyl)thiazole-5-carboxylic acid (TA), an antibacterial compound, was used as a capping agent. Through hydrolytic polymerization with caprolactam, we synthesized intrinsically antimicrobial nylon 6 with trifluoromethyl thiazole group. The results show that the prepared antibacterial nylon 6 possesses good mechanical properties and thermal stability, with a tensile strength exceeding 60 MPa and a thermal decomposition temperature above 390 °C. Furthermore, the addition of only 3 wt% TA completely eradicates E. coli and S. aureus , demonstrating excellent antibacterial efficacy.
研究领域:
材料科学
·
生物学
·
医学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2019
·
IF 4.561
Yi Li,Songwei Zhang,Qi Ding,Baofeng Qin,Litian Hu
Ionic liquids (ILs) are extensively used in many fields owing to their attractive characteristics. Good structure designability provides ILs an opportunity to integrate multiple functions into their structures, which could promote their industrial applications as versatile materials. In this study, three 4, 6-dimethyl-2-mercaptopyrimidine (DMMP) based phosphonium ILs were firstly synthesized. The corrosion inhibition behaviors of these ILs for mild steel in 0.5 M H 2 SO 4 aqueous solutions were investigated by electrochemical tests. Results indicated that all of the three ILs exhibited surprising inhibition efficiencies as high as 99%, even at an ultralow concentration of 0.1 mM. The ILs' adsorption behavior on surface obeys Langmuir isotherm, indicating that the ILs inhibit corrosion of mild steel by monolayer adsorption on the mild steel surface. Moreover, due to the superior adsorption capacity on steel surface, DMMP based ILs are expected have great application potentials as high-performance lubricating materials. As expected, DMMP based ILs showed excellent lubrication performances both at 30 °C and 100 °C as compared to PAO and 1-butyl-3-methylimidazolium tetrafluoroborate (LB104). Surface analyses indicated that tribofilms consist of ILs adsorption layer and tribochemical products, such as FeS, Fe 2 O 3 and organic compounds containing C O bonds, are responsible for the predominant lubrication performances. Therefore, versatile ILs designed in this paper have gathered two significant abilities for industrial applications, which are high corrosion inhibiting properties and excellent lubrication performances. This work is believed to be instructive for designing multifunctional ILs and promoting the ILs' application in industry in the future.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
·
2024
·
IF 6.9
Linquan Dai,Bo Feng,Mengyan Tang,Yuangan Chen
It is challenging to separate between molybdenite and chalcopyrite due to their comparable hydrophobic characteristics. Inorganic depressants were previously used to separate two minerals, but the results were unsatisfactory and polluted the environment. In this study, the molybdenite and chalcopyrite were separated using a highly effective and ecologically safe depressant, 2,4-Diamino-6-hydroxypyrimidine (DAHP). According to the single mineral experiment, chalcopyrite is totally depressed while molybdenite has superior floatability. The efficacy of DAHP as the depressant was validated by further artificially mixed mineral flotation experiments, indicating the possibility of separating chalcopyrite and molybdenite. The adsorption capacity experiment results showed that the adsorption capacity of DAHP on the surface of chalcopyrite was greater than that on the surface of molybdenite. Zeta potential experiment results show that DAHP is adsorbed on the surface of chalcopyrite and molybdenite through static electrostatic interactions . X-ray photoelectron spectroscopy (XPS) experiment results show that DAHP is mainly adsorbed on chalcopyrite surface through –NH 3 + group, which hinders the adsorption of kerosene. The electrostatic contact between DAHP and molybdenite has the least effect on kerosene adsorption. This study shows that DAHP has the potential to separate chalcopyrite and molybdenite as an efficient and environmentally friendly depressant.
研究领域:
矿物加工工程
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环境科学
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产品关联
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2018
·
IF 3.141
Rui Wang,Lixin Wu,Dongxian Zhuo,Jianhua Zhang,Youdan Zheng
A 3D graphene network was constructed in polyamide 6 (PA6) monomers through the reduction and self-assembly of graphene oxide (GO), and then PA6 nanocomposites with low graphene content were fabricated through in situ polymerization. The effects of the 3D graphene network on the structure and properties of the PA6 were systematically investigated. Results show that the 3D graphene network can significantly improve the thermal conductivity of PA6. In the case of the PA6 with only 0.25 wt % graphene, its thermal conductivity is 0.69 W/(m K), about 2.88 times of that of the pure PA6. This improvement is attributed to the more-compact thermal conductive paths of the 3D graphene network, and its stronger interfacial interaction with PA6 in this work compares with those of pre-synthesized free-standing 3D graphene networks. Moreover, the mechanical properties and water resistance of PA6 also have significantly improved with the incorporation of the 3D graphene network.
研究领域:
材料科学
·
纳米复合材料
✓ 已验证
DOI
高影响因子
TALANTA
·
2025
·
IF 6.1
Xinyu Zhang,Xuan Zhou,Quan Wan,Taolei Sun,Guanbin Gao
Prussian blue analogue nanozymes (PBANZs) have been widely employed in the colorimetric detection of various organic small molecules due to their peroxidase-like activity. However, the practical applications of PBANZ are limited by its narrow operating pH range, insufficient catalytic activity, and poor stability. In this study, we synthesized a novel Cu 2 Fe(CN) 6 @PVP PBA nanozyme (Cu-PBANZ) using polyvinylpyrrolidone (PVP) as a capping ligand. This novel Cu-PBANZ not only exhibited enhanced peroxidase-like activity and improved stability under near-neutral conditions but also demonstrated higher sensitivity and a broader linear range in the detection of hydrogen peroxide (20–4000 μM, LOD 5 μM) and ascorbic acid (10–2000 μM, LOD 3.9 μM). Besides, a smartphone-based platform was developed for detecting AA content in fruits, achieving a detection limit of 7.8 μM. Both UV–Vis spectrophotometry and smartphone-based colorimetry were validated with recovery rates of 95.1 %–106.7 % and 94.8 %–108.9 %, respectively. This study proposed a promising biosensor incorporating Cu-PBANZ for rapid colorimetric detection of AA in fruits using a smartphone.
研究领域:
生物化学
·
食品科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2018
·Vol. 137
·期 2
·47298
·
IF 1.901
Wei Hou,Yifan Fu,Cen Zeng,Na Liu,Cuiyu Yin
In this study, the nanocomposites are prepared which used polyamide 6 (PA6) composite as matrix, melamine cyanurate (MCA) as fire retardant and attapulgite (AT) as synergistic agent. The mathematical model between MCA content, AT content, and limited oxygen index (LOI) is established by multiple linear regression fitting. The polymer materials are characterized using Fourier transform infrared spectroscopy, X-ray diffraction, Thermogravimetric Analysis, and scanning electron microscopy. Through response surface methodology, the important variables (polymerization time, the content of MCA, and the content of AT) affecting the mechanical strength of composites are modeled. Results demonstrate that when the t is 0.6 h, the AT content is 6.2%, and the MCA content is 11.5%, the mechanical properties of the PA6/MCA/AT composite are up to 44.81 MPa, and the sample passes the UL-94 V-0 flammability rating, and the LOI reaches 27.9%. Therefore, polymers with highly effective flame retardancy and optimal mechanical properties are prepared. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020 , 137 , 47298.
研究领域:
材料科学
·
聚合物化学
✓ 已验证
DOI
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2022
·
IF 3.841
Mengyu Zhu,Jun Lu,Linchang Dong,Shuheng Hu,Shuchuan Peng,Chengzhu Zhu
The possible photochemical transformation pathways of chlorophenols (2, 6-dichlorophenol and 2-chlorophenol) with superoxide anion radical (O 2 ·− ) were studied by steady-state irradiation and 355 nm laser flash photolysis technique. O 2 ·− was generated by irradiating riboflavin O 2 -saturated solution with an UVA light (maximum at 365 nm). The steady-state experimental results suggested that the transformation efficiency of chlorophenols improved with the increase of the initial riboflavin concentration and solution initial pH value, while the increase of chlorophenols concentration would inhibit the photochemical reaction. The second-order rate constant of the reaction of O 2 ·− with 2, 6-DCP phenoxyl radical (2, 6-DCP · ) and 2-CP phenoxyl radical (2-CP · ) were determined as (8.39 ± 0.99) × 10 9 L mol −1 s −1 and (5.17 ± 0.68) × 10 9 L mol −1 s −1 by laser flash photolysis techniques, respectively. The transformation of chlorophenols was accompanied by the formation of Cl − induced by superoxide radicals after the mixed riboflavin and chlorophenols solution with UVA irradiation. The main conversion products of the reaction between 2, 6-DCP and O 2 ·− were identified by GC-MS, as 2-chlorophenol, 2, 6-dichloro-1, 4-benzoquinone, 2, 6-dichloro-hydroquinone and 3-chlorocatechol, while 2-CP with O 2 ·− was 2-chloro-1, 4-benzoquinone, 2-chlorohydroquinone and phenol, respectively. The transformation pathways of 2, 6-DCP and 2-CP with O 2 ·− were also proposed.
研究领域:
环境科学
·
化学
✓ 已验证
DOI
高影响因子
Journal of Water Process Engineering
·
2025
·
IF 6.7
Liling Zeng,Xianyan Ao,Manli Xu,Yunqian Zhang,Zhu Tao
The synergistic removal of organic pollutants by adsorption and photocatalysis can be achieved by adsorption of enriched pollutants, followed by photocatalytic degradation to decompose the pollutants into non-toxic substances. In this work, a category of adsorption-photocatalytic bifunctional composite materials Q[6]-HPAs have been developed through the self-assembly of cucurbit[6]uril (Q[6]) and heteropoly acids (HPAs) like phosphomolybdic acid (PMA), phosphotungstic acid (PTA) and silicotungstic acid (STA). These composites exhibit enhanced surface area, structural stability, and extended light absorption into the visible range. Notably, Q[6]-HPAs have surface charge properties that attract cations and an energy band structure suitable for the generation of reactive oxygen species, thus possessing the potential for efficient adsorption and photodegradation of cationic pesticides. Among which, Q[6]-PMA and Q[6]-PTA removed over 95 % of diquat and paraquat through sequential adsorption and photodegradation. Electrostatic attraction drives the adsorption process, and ·O 2 − and ·OH radicals detected via Electron Spin Resonance (ESR) are the key to photodegradation. Ultimately, Liquid Chromatography-Mass Spectrometer (LC-MS) analysis revealed potential degradation intermediates and products, and toxicity analysis was performed.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
·
2019
·Vol. 2019
·期 9
·1212-1219
·
IF 2.578
Xin Yu Deng,Kai Chen,Ming-Dong Chen,Li Bin Lü,Zhu Tao
Graphical The probe responds to Cs + cations in alkali metal systems, Ba 2+ and Sr 2+ cations in alkaline earth metal systems; Eu 3+ , Tm 3+ , and Yb 3+ cations in lanthanide systems, and Cr 3+ , Fe 3+ , and Hg 2+ cations in systems containing transition and other metal cations, by obvious fluorescence quenching. Based on the study of a known host–guest inclusion complex comprising cucurbit[6]uril (Q[6]) and a hemicyanine dye, trans -4-[4-(dimethylamino)styryl]-1-pyridinium iodide ( t -DSMI), a water-soluble symmetric tetramethylcucurbit[6]uril (TMeQ[6]), was selected to construct a t -DSMI-based probe to test the response to various metal cations in neutral water. The experimental results revealed that the probe responded to Cs + cations in alkali metal systems, Ba 2+ and Sr 2+ cations in alkaline earth metal systems, Eu 3+ , Tm 3+ and Yb 3+ cations in lanthanide systems, and Cr 3+ , Fe 3+ and Hg 2+ cations in systems containing transition and other metal cations, via obvious fluorescence quenching.
研究领域:
化学
·
分析化学
✓ 已验证
DOI
高影响因子
Journal of Functional Foods
·
2016
·
IF 3.973
Yang Xu,Qilong Wang,Yingshu Feng,Caleb Kesse Firempong,Yuan Zhu,Emmanuel Omari-Siaw,Yuanyuan Zheng,Zunqin Pu,Ximing Xu,Jiangnan Yu
The purpose of this study was to develop a [6]-Gingerol-loaded self-microemulsifying drug delivery system ([6]-Gingerol-SMEDDS) for oral administration and enhanced bioavailability of the drug. The [6]-Gingerol-SMEDDS, consisting of oils (ethyl oleate), surfactant (Cremophor EL35) and co-surfactant (1,2-propanediol), showed an acceptable spherical nanoparticle with stable physicochemical properties such as the mean droplet size (73.06 ± 0.49 nm), zeta potential (−2.45 ± 0.41) and encapsulation efficiency (89.40 ± 1.11%). The in vitro release of [6]-Gingerol from the delivery system in the three different media (HCl, pH 1.2; Double distilled water, pH 7.0; phosphate buffer solution, pH 7.4) was significantly higher than in the free drug. The [6]-Gingerol-SMEDDS also exhibited prolonged plasma circulation which led to 6.58-fold increase in oral bioavailability compared with the free drug. These findings indicated that the developed [6]-Gingerol-SMEDDS could be a promising alternative in improving the solubility and oral bioavailability of [6]-Gingerol, as well as increasing its biological applications.
研究领域:
药剂学
·
药物递送
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL BIOCHEMISTRY
·
2021
·
IF 3.365
Haiyan Zhou,Guorui Zhong,Jing Bai,Xiaolei Li,Wen Peng,Lei Zhang,Jing Li
The urate transporter 1 (URAT1) inhibitors were considered a very promising class of uricosuric agents for the treatment of hyperuricemia and gout. In vitro activity testing of these compounds has been conducted by radio-labeling uric acid for a long time. However, relatively few offer the convenience and speed of fluorescence-based assays. Herein, we report the development of a non-radioactive cell-based method for the screening of URAT1 inhibitors using the human embryonic kidney 293T cells stably expressing human URAT1, and 6-carboxyfluorescein (6-CFL) as a substrate. The URAT1-mediated transport of 6-CFL was time dependent and saturable (Km = 239.5 μM, Vmax = 6.2 pmol/well/min, respectively). Molecules known to interact with organic anion transporters, including benzbromarone , probenecid , and lesinurad, demonstrated concentration-dependent inhibition of 6-CFL transport by URAT1. Moreover, we screened a small subset of compounds, and identified compound 4 as a promising URAT1 inhibitor. This in vitro assay may be employed to screen for novel URAT1 inhibitors, which are effective against hyperuricemia.
研究领域:
药理学
·
生物化学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
·
2025
·
IF 4.9
Yuzhen Kang,Dongyu Wu,Tiantian Zhang,Yue Zhang,Yan Zhong,Shiqi Chen,Xiaoyu Wang,Xuyu Chai
In this study, we investigated the feasibility of using poly(N-acryloyl 6-aminocaproic acid) (PA6ACA) as a pH-responsive polymer for oral enteric drug delivery. PA6ACA, characterized by its acylamino group, carboxyl group, and flexible 5-carbon chain, demonstrates pH sensitivity due to the presence of ionizable carboxyl groups and hydrogen bonding interactions between the carboxyl and amino moieties. Our research focused primarily on the preparation, characterization, and evaluation of enteric drugs delivered via PA6ACA. We evaluated the morphology, structure, thermal properties, and crystallinity of PA6ACA. Cytotoxicity experiments conducted in Caco-2 cells and the oral administration studies in mice provided preliminary safety evidence for PA6ACA. Three model drugs (budesonide, sulfasalazine, and diclofenac sodium) were employed to fabricate drug-polymer coprecipitates, and PA6ACA exhibited high loading capacities for these drugs. Furthermore, the drug release profiles revealed that the drug-loaded polymers were resistant to acid at pH 1.0 and nearly completely dissolved within the next 8 h at pH 6.8. The kinetic model fitting results indicated that the release of drugs from the coprecipitates were more consistent with the Higuchi model, suggesting minimal polymer swelling in the media and a primary drug release mechanism via diffusion. Based on these findings, we conclude that PA6ACA holds promise for the development of innovative and efficient intestine-specific drug delivery systems.
研究领域:
药剂学
·
生物材料
·
药物化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）