Journal of Materials Chemistry B
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2020
·Vol. 8
·期 7
·1396-1404
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IF 5.344
Shang-Qing Zhang,Xun Liu,Qi-Xuan Sun,Omar Johnson,Ting Yang,Ming-Li Chen,Jian-Hua Wang,Wei Chen
In this study, CuS@PDA nanoparticles were synthesized and used to create a novel tumor-targeting nanocomposite platform composed of copper sulfide@polydopamine–folic acid/doxorubicin (CuS@PDA–FA/DOX) for performing both photothermal and chemotherapeutic cancer treatment. The nanocomposite platform has ultrahigh loading levels (4.2 ± 0.2 mg mg−1) and a greater photothermal conversion efficiency (η = 42.7%) than CuS/PDA alone. The uptake of CuS@PDA–FA/DOX nanocomposites is much higher in MCF-7 cells than in A549 cells because MCF-7 cells have much higher folic acid receptors than A549. Under near infrared (NIR) irradiation, the CuS@PDA–FA/DOX system using a synergistic combination of photothermal therapy and chemotherapy yields a better therapeutic effect than either photothermal therapy or chemotherapy alone. The treatment is very effective with the cell viability is only 5.6 ± 1.4%.
研究领域:
肿瘤学
·
药剂学
·
生物医学工程
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DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2016
·
IF 4.712
Xiangheng Niu,Yanfang He,Jianming Pan,Xin Li,Fengxian Qiu,Yongsheng Yan,Libo Shi,Hongli Zhao,Minbo Lan
Nanosized materials acting as substitutes of natural enzymes are currently attracting significant research due to their stable enzyme-like characteristics, but some flaws of these nanozymes , including their limited catalytic rate and efficiency, need to be remedied to enable their wider applications. In this work, we verify for the first time the catalytic behavior of uncapped nanobranch-based CuS clews as a peroxidase mimic. XRD , XPS , SEM, and TEM proofs demonstrate that high-purity CuS clews composed of intertwined wires with abundant nanodendrites outside are successfully produced via a facile one-pot hydrothermal synthesis approach, with thiourea as both the sulfion source and the structure-directing agent. The synthesized CuS can catalytically oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) by H 2 O 2 to trigger a visible color reaction with rapid response (reaching a maximum change within 5 min). The proposed CuS nanozyme exhibits preferable catalytic kinetics over natural horseradish peroxidase (HRP). This outstanding activity primarily results from the large surface area and rich sites exposed by the uncapped unique structure. Under optimized conditions, the fabricated sensing system provides linear absorbance (652 nm) changes in the H 2 O 2 concentration range of 0.2˜130 μM, with a detection limit of as low as 63 nM. When coupled with glucose oxidase (GOD), the system is demonstrated to be capable of monitoring glucose in blood samples with excellent performance.
研究领域:
生物化学
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纳米医学
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产品关联
DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2021
·Vol. 45
·期 15
·6895-6903
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IF 3.591
Mingqian Wang,Haomiao Zhu,Jian Shen
Designing antibacterial nanomaterials with outstanding antibacterial effects has great practical significance. In this work, we developed a facile therapy tool that used CuS nanoparticles to modify graphite oxide (GO) sheets to form CuS@GO nanocomposites (NCs). At the same time, molecular dynamics simulation proved that compared with pure GO, the addition of PEG can effectively disperse GO and facilitate the enrichment of CuS on the GO surface. Then, a CuS@GO–CS hydrogel was prepared by electrostatic interaction between the CuS@GO NCs and CS hydrogel and the inherent antibacterial properties of the CS hydrogel were investigated. Meanwhile, the CuS@GO–CS hydrogel showed enhanced photothermal antibacterial properties to effectively prevent the bacteria. In vitro experiments indicated that a CS hydrogel has a certain antibacterial effect on Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). Moreover, the CuS@GO NCs have excellent photothermal properties, and the CuS@GO NCs loaded into CS hydrogel significantly enhanced the antibacterial efficacy for S. aureus and E. coli under near-infrared (NIR) laser irradiation. Taken together, the antibacterial CuS@GO–CS hydrogel with good antibacterial properties offers significant promise as an antibacterial nanomaterial for enhanced photothermal antibacterial therapy.
研究领域:
材料科学
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生物医学工程
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抗菌材料研究
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产品关联
DOI
高影响因子
ChemistrySelect
·
2023
·Vol. 8
·期 17
·e202300167
·
IF 2.1
Lihui Xu,Jun Li,Hong Pan,Liming Wang,Yadong Liu,Yong Shen
Graphical CuS/RGO/PDMS@fabric with UV protection and photocatalysis were prepared via dip-pad-dry method. The obtained fabrics showed excellent superhydrophobic properties with the water contact angle (WCA) about 157.8°. Due to synergistic effect between the hierarchical structures and PDMS, the obtained cotton fabrics showed excellent superhydrophobic properties and durabilities. The superhydrophobic cotton fabrics possessed excellent robustness against 1000 rubbing cycles and 96 h UV irradiation. More importantly, the functional cotton fabric also showed good UV protection performance, with UPF of 851.2, UVA and UVB of 0.15 % and 0.06 %, respectively. In the present study, the superhydrophobic cotton fabrics with ultraviolet (UV) resistance and photocatalytic properties were fabricated by polydimethylsiloxane (PDMS) and CuS/reduced graphene oxide (RGO). The CuS/RGO particles enhanced the surface roughness, and PDMS was used to reduce the surface energy of cotton fabrics and increase the adhesion of CuS/RGO particles to cotton fabrics. The water contact angle (WCA) of coated cotton fabrics could reach ∼158.4°, endowing the fabrics with excellent self-cleaning and oil-water separation properties. It is confirmed that cotton fabric can obtain superhydrophobic property by adjusting the concentration of CuS/RGO and PDMS. Thanks to the good photocatalytic activity and excellent ultraviolet absorption capacity of the composite material, the superhydrophobic fabrics possessed outstanding ultraviolet resistance with the maximum UV protection factor (UPF) of 851.2 and photocatalytic performance with the photocatalytic degradation rate of methylene blue 92 %. Furthermore, the prepared cotton fabric retained superhydrophobicity after 90 h UV irradiation or 2000 cycles rubbing. The flexible superhydrophobic cotton fabrics with UV protection had promising application prospects in various fields.
研究领域:
材料科学
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纺织工程
·
纳米技术
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产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2017
·
IF 2.986
Jimin Du,Mengke Yang,Fangfang Zhang,Xuechun Cheng,Haoran Wu,Huichuang Qin,Qingsong Jian,Xialing Lin,Kaidi Li,Dae Joon Kang
Photoelectrochemical (PEC) water splitting using high-performance catalysts shows considerable promise in generating environment-friendly hydrogen energy. Its practical applications, however, suffer from several shortcomings, such as low photocurrent density, large onset-voltage value, and poor durability. In this study, CuS and CdS quantum-dot-cosensitized porous TiO 2 -based PEC catalysts (CuS-CT) have been successfully synthesized via in situ sulfuration of CuO and CdO coexisting inside a porous TiO 2 monolith by a hydrothermal method . Compared to porous TiO 2 , CuS-sensitized porous TiO 2 (CuS-TiO 2 ), and CdS-sensitized porous TiO 2 (CdS-TiO 2 ) in terms of PEC performance, the CuS-CT photoanode exhibited a significantly high anodic photocurrent for water splitting under simulated sunlight radiation. The photocurrent produced by the optimized sample of 7% CuS-5% CdS-TiO 2 (7% CuS-CT) was nearly 2.7 times higher than that of pure porous TiO 2 at 1.0 V versus a reversible hydrogen electrode (RHE). Porous TiO 2 possesses large surface areas that can drive fast electrolyte transport and afford more surface reaction active sites. On the other hand, CuS and CdS quantum dots not only broaden the visible light absorption range, but also improve photoinduced electron-hole separation efficiency. The co-sensitized multi-nanostructures photoanodes lead to a remarkable and promising application in PEC water splitting reactions.
研究领域:
材料科学
·
光化学
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能源材料
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纳米技术
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产品关联
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2018
·
IF 8.173
Yunfei Tang,Yun Chai,Xiaoqiang Liu,Lele Li,Liwei Yang,Peipei Liu,Yanmei Zhou,Huangxian Ju,Yunzhi Cheng
In this work, a CuS-TiO 2 heterojunction composite was prepared by dispersedly depositing CuS nanoparticles on TiO 2 nanospheres surface with a hydrothermal method , and was then used to construct a photoelectrochemical (PEC) aptasensor for sensitive detection of microcystin-LR (MC-LR) in aquatic environment. The energy bands of CuS nanoparticles and spherical anatase TiO 2 were well matched, which enhanced the photo-to-current conversion efficiency. The composite exhibited the enhanced visible light absorption , the improved separation of photo-generated charges, and the reduced self-aggregation of CuS nanoparticles, leading to the enhanced photocurrent response. The PEC aptasensor was constructed by immobilizing CuS-TiO 2 composite on ITO electrode with chitosan film that further covalently bound aminated aptamer. After the target, microcystin-LR (MC-LR) as an analyte model, was captured by the aptamer on the aptasensor, it could be oxidized by the photo-generated hole to impede the electron-hole recombination and further amplify the photocurrent. The PEC aptasensor showed superior analytical performance for MC-LR with a linear range of 5.0 × 10 −5 nM to 250 nM and a detection limit of 2.0 × 10 −5 nM. The detection results with the aptasensor for practical water samples indicated its promising application in environmental monitoring.
研究领域:
环境科学
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分析化学
·
材料科学
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产品关联
DOI
PubMed
高影响因子
CRYSTENGCOMM
·
2018
·Vol. 20
·期 41
·6565-6572
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IF 3.304
Jiani Gu,Yi Xie,Wenhui Chen,Chao Hu,Fen Qiao,Zhiyuan Xu,Xiaoqing Liu,Xiujian Zhao,Gaoke Zhang
We report inter-diffusion of as-synthesized covellite CuS nanocrystals (NCs) with Cu2+ cations at room temperature in the presence of a mild reducing agent (i.e., ascorbic acid). Unlike the previously-reported incorporation of Cu+ or Cu2+ ions with CuS that generates homogenous Cu2−xS NCs, the controlled diffusion of Cu2+ ions into the CuS NCs allows the formation of a unique CuS@Cu2−xS core–shell-like nanostructure as the intermediate and Cu2S NCs in the presence of excess Cu2+ ions. The CuS@Cu2−xS core–shell nanostructure can evolve into homogenous Cu2−xS NCs by further cation diffusion from the Cu2−xS shell toward the center (i.e. the CuS core) under E-beam irradiation during TEM test or when the core–shell NCs are stored in toluene for some time (e.g. four weeks). Notably, the CuS/paraffin composite with filler loading of 50 wt% and thickness of 1.95 mm displays a minimum reflection loss (RL) of −54.84 dB at 12.6 GHz. By adjusting the thickness in the range of 1–5 mm, the effective absorption bandwidth (below −10 dB, 90% microwave absorption) could reach 15 GHz (3–18 GHz). In particular, the diffusion of Cu2+ into CuS NCs leads to dampening of the NIR plasmon absorbance and a decrease in free carrier (i.e., hole) density and conductivity, which accounts for the confinement effect on the microwave absorption properties of the resulting samples.
研究领域:
材料科学
·
纳米技术
·
电磁材料
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Wenhui Chen,Jiayao Wang,Chiyin Zhang,Shaokui Cao,Jingguo Li,Jun Shi
Hollow natural polysaccharide microcapsules have broad applications in drug delivery field due to their excellent biocompatibility and drug loading efficiency. In this paper, pH/near-infrared (NIR) dual-responsive microcapsules composed of hyaluronic acid (HA), chitosan (CS) and hollow CuS (HA/CS/HA@CuS) had been fabricated via a layer-by-layer (LbL) approach. The negative charge, rough surface and hollow structure of microcapsules are very favorable for loading positively charged DOX. As a result, hollow microcapsules display a high drug loading efficiency of 91.15 %. The variation in the degree of amino ionization at different pH values leads to the changes in the electrostatic force between CS/HA multilayers, resulting in the structural change in microcapsules. Therefore, microcapsules exhibit significant pH-responsive drug release properties. In addition, hollow CuS nanoparticles with excellent photothermal conversion ability are capped on the multilayer surface, enabling microcapsules to exhibit excellent NIR-responsive drug delivery properties. Overall, hyaluronic acid/chitosan-based hollow microcapsules with notable pH/NIR dual-responsiveness have been prepared, which can be used as a potential drug carrier for controlled drug delivery and photothermal chemical combination therapy.
研究领域:
药学
·
材料科学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Xiaoqing Ma,Kang-lai Tang,Kang Lu,Chenke Zhang,Wenbing Shi,Wenxi Zhao
Designing metal sulfides with unique configurations and exploring their electrochemical activities for hydrogen peroxide (H2O2) and hydrazine (N2H4) is challenging and desirable for various fields. Herein, hollow microflower-like CuS@C hybrids were successfully assembled and further exploited as a versatile electrochemical sensing platform for H2O2 reduction and N2H4 oxidation, of which the elaborate strategies make the perfect formation of hollow architecture, providing considerable electrocatalytic sites and fast charge transfer rate, while the appropriate introduction polydopamine-derived carbon skeleton facilitates the electronic conductivity and boosts structural robustness, thus generating wide linear range (0.05–14 and 0.01–10 mM), low detection limit (0.22 μM and 0.07 μM), and a rather low overpotential (−0.15 and −0.05 V) toward H2O2 and N2H4, as well as good selectivity, excellent reproducibility, and admirable long-term stability. It should be highlighted that the operating potentials can compare favorably with those of some reported H2O2 and N2H4 sensors based on noble metals. In addition, good recoveries and acceptable relative standard deviations (RSDs) attained in serum and water samples fully verify the accuracy and anti-interference capability of our proposed sensor systems. These results not only elucidate an effective structural nanoengineering strategy for electroanalytical science but also advance the rational utilization of H2O2 and N2H4 in practicability.
研究领域:
材料科学
·
分析化学
·
生物医学工程
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产品关联
DOI
PubMed
高影响因子
Crystals
·
2025
·Vol. 15
·期 6
·505
·
IF 2.4
Xinyuan Zhang,Meng Sun,Haibo Guo,Ming Su
Pursuing cost-effective non-precious metal electrocatalysts is a key challenge in the field of sustainable energy conversion. Transition metal dichalcogenides, known for their unique electronic structure, demonstrate superior electrocatalytic capabilities for the hydrogen evolution reaction (HER), yet their effectiveness is still lacking. In the present study, a CuS/Co3S4@MWCNT composite was fabricated via single-step hydrothermal synthesis for HER applications. This catalyst exploited the synergistic effects between CuS and Co3S4to increase edge site functionalities and metallic conductivity, thereby resulting in high catalytical activity within the material. Furthermore, the incorporation of multi-walled carbon nanotubes (MWCNTs) into the composite effectively enhanced electron transfer kinetics throughout the HER process. Notably, thiourea serves a dual function in this synthesis, acting both as a reducing agent and as a sulfur source for the formation of metal sulfides. When evaluated in a 1 M KOH alkaline electrolyte, the synthesized nanocomposite exhibited a minimal overpotential of 300 mV to reach a current density of 10 mA/cm2, and a Tafel slope of merely 76.2 mV/dec, indicative of its good HER catalytic activity. These findings underscore the composite’s potential for application in hydrogen production technologies.
研究领域:
材料科学
·
电化学
·
能源转换
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产品关联
DOI
高影响因子
Scientific Reports
·
2022
·Vol. 12
·期 1
·1-10
·
IF 4.996
Tan Meina,Qin Yang,Wang Yiping,Zhang Fazhi,Lei Xiaodong
We propose a new Cu–Al dual-ion battery that aqueous solution composed of LiCl, CuCl and AlCl 3 (LiCuAl) is used as the electrolyte, CuS is used as the cathode of aqueous aluminum ion battery for the first time and copper foil is used as the anode. The assembled Cu–Al dual-ion battery yields a reversible capacity of 538 mA h/g at 200 mA/g, and exhibits longterm cycling stability of over 200 cycles with 88.6% capacity retention at 1000 mA/g. Above excellent performance is inseparable from the three components of LiCuAl electrolyte and electrode materials. The Al-storage mechanism of CuS is proposed that the S–S bond in CuS lattice interacts with aluminum ions during the aluminum storage process. In addition, the charging and discharging process does not cause irreversible damage to the S–S bond, thus Cu–Al dual-ion battery with CuS as cathode shows great cycle stability.
研究领域:
电化学
·
材料科学
·
能源存储
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2020
·
IF 10.652
Qinyuan Hong,Haomiao Xu,Jiaxing Li,Wenjun Huang,Ping Liu,Zan Qu,Naiqiang Yan
Inducing gaseous substances to migrate inward into a solid material is one of the effective methods to improve the interfacial adsorption stability. However, the gaseous mercury (Hg 0 ) adsorption on bulk material, especially mineral sulfides , generally occurred on the outer surface owing to their compact structure, resulting in the low bonding stability. This study prepared porous [email protected] with different shell thickness to investigate mercury adsorption performance and bonding stability. The porous shell structure enabled Hg 0 to migrate inward into [email protected] Such an inducing effect, on one hand, improved the mercury adsorption performance due to the increase of active sites with the thickened shell. On the other hand, the mercury bonding stability was enhanced along with the increase of shell thickness. The initial mercury desorption temperature gradually increased from 50 to higher than 100 °C, and meanwhile, the desorption peak temperature increased from 150 to 275 °C. The improved bonding stability also enlarged its adaption to a wider temperature window (50–150 °C). Moreover, the optimal [email protected] has a saturated adsorption capacity of 60.53 mg/g, and it has high resistance against O 2 , SO 2, and H 2 O. This work thus offers a promising thickness-induced method to enhance the mercury bonding stability on sulfides.
研究领域:
环境科学
·
材料科学
·
化学工程
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）