APPLIED SURFACE SCIENCE
·
2013
·
IF 2.112
Ruifeng Li,Chunfeng Cai,Lian Hu,Huizhen Wu,Wenhua Zhang,Junfa Zhu
Band alignments of ZnO/CdSe nanocrystal quantum-dots (NQDs) heterojunctions are determined by ultraviolet photoelectron spectroscopy using synchrotron radiation source. To obtain ideal heterojunction interface, 1,2-ethanedithiol was used for CdSe NQDs as a ligand substitute. A type II band alignment of the ZnO/CdSe NQDs heterojunctions with changeable band offsets by varying the sizes of CdSe NQDs is concluded. The tunable band alignment of ZnO/CdSe NQDs heterojunctions is beneficial to the improvement of the design and fabrication of quantum-dot-sensitized solar cells.
研究领域:
材料科学
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光电子学
·
可再生能源
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2016
·
IF 4.758
Qiao Liu,Ying Yang,Xing-Pei Liu,Yu-Ping Wei,Chang-Jie Mao,Jing-Shuai Chen,He-Lin Niu,Ji-Ming Song,Sheng-Yi Zhang,Bao-Kang Jin,Meng Jiang
A novel highly electrochemiluminescence (ECL) metal-organic frameworks (MOFs) have been successfully synthesized by combining CdSe quantum dots (QDs) and MIL-101 in one step by facile hydrothermal method. The as-prepared MIL-101-CdSe nanocomposites combine a high ECL activity and sensing selectivity derived from CdSe and the highly selective adsorption and efficient accumulation performance of MOFs. The selective accumulation effect of MOFs can greatly amplify the sensing signal and specificity of the ECL probe. The resulting nanocomposites were applied to develop an ultrasensitive ECL immunosensor for detection of carcinoembryonic antigen (CEA). This ECL immunosensor has a sensitive response to CEA in a linear range of 10 −12 mg mL −1 –10 −4 mg mL −1 with a detection limit of 0.33 fg mL −1 . The developed ECL immunosensor shows high sensitivity, good stability, specificity, and excellent reproducibility, and can be used for detection of real samples, which providing potential application in clinical detection.
研究领域:
材料科学
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分析化学
·
生物医学工程
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产品关联
DOI
高影响因子
Nanoscale Research Letters
·
2018
·Vol. 13
·期 1
·1-7
·
IF 3.125
Wang Shan,Liu Ruiqing,Li Chenchen
In the presence of Hg 2+ , a fluorescence resonance energy transfer (FRET) system was constructed between CdSe quantum dots (QDs) (donor) and g-C 3 N 4 (receptors). Nanocomposites of g-C 3 N 4 supported by CdSe QDs (CdSe QDs/g-C 3 N 4 nanosheets) were fabricated through an electrostatic interaction route in an aqueous solution. The nanocomposites were characterized by X-ray photoelectron spectroscopy, X-ray diffraction, Fourier-transform infrared spectroscopy, and transmission electron microscopy. Results showed that the g-C 3 N 4 nanosheets were decorated randomly by CdSe QDs, with average diameter of approximately 7 nm. The feasibility of the FRET system as a sensor was demonstrated by Hg (II) detection in water. At pH 7, a linear relationship was observed between the fluorescence intensity and the concentration of Hg (II) (0–32 nmol/L), with a detection limit of 5.3 nmol/L. The new detection method was proven to be sensitive for detecting Hg 2+ in water solutions. Moreover, the method showed high selectivity for Hg 2+ over several metal ions, including Na + , Mg 2+ , Ca 2+ , Pb 2+ , Cr 3+ , Cd 2+ , Zn 2+ , and Cu 2+ . The CdSe QDs/g-C 3 N 4 nanosheet conjugate exhibited desirable long-term stability and reversibility as a novel FRET sensor. The novel FRET-based fluorescence detection provided an attractive assay platform for quantifying Hg 2+ in complex water solutions.
研究领域:
分析化学
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环境科学
·
纳米技术
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF NANOPARTICLE RESEARCH
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2015
·Vol. 17
·期 11
·1-8
·
IF 2.184
Chen Jun,Yang Xiao-Quan,Qin Meng-Yao,Zhang Xiao-Shuai,Xuan Yang,Zhao Yuan-Di
In this paper, polyethylene glycol-phospholipid structure is used to synthesize hybrid cluster of 40–50 nm diameter that contains hydrophobic bismuth sulfide nanoparticles and CdSe/ZnS quantum dots. The composite probe’s toxicity, CT imaging, and fluorescence imaging performance are also studied. Experimental results show that the nanocomposite hybrid cluster has obvious CT contrast enhancement and fluorescence imaging capability in vitro even after cellular uptake. It gives a CT number of 700 (Hounsfield units) at 15 mg/mL, higher than that of the current iobitridol CT contrast agent. 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide experiment reveals that it has low cytotoxicity at concentration up to of 3.14 mg/mL of Bi, indicating the composite probe has potential ability for CT and fluorescence bimodal imaging.
研究领域:
医学影像学
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纳米医学
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生物材料学
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产品关联
DOI
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2020
·Vol. 412
·期 13
·3073-3081
·
IF 3.637
Cheng Jin-long,Liu Xing-Pei,Chen Jing-Shuai,Mao Chang-jie,Jin Bao-Kang
In this work, an electrochemiluminescence (ECL) biosensor was fabricated for the selective detection of vascular endothelial growth factor (VEGF 165 ). g-C 3 N 4 /PDDA/CdSe nanocomposites were used as the ECL substrate. Then, DNA labeled at the 5′ end with amino groups (DNA 1 ) was immobilized on the surface of g-C 3 N 4 /PDDA/CdSe nanocomposite-modified glassy carbon electrode (GCE) by amido linkage. AuNP-labeled target DNA (Au-DNA 2 ) could hybridize with DNA 1 to form a double strand. The ECL of the g-C 3 N 4 /PDDA/CdSe nanocomposite was efficiently quenched due to the resonance energy transfer between CdSe QDs and Au NPs. After VEGF 165 was recognized and bound by Au-DNA 2 , the double helix was disrupted, and the energy transfer was broken. In this case, Au-DNA 2 was released from the electrode surface, and the ECL intensity recovered to a higher level. Under optimal conditions, this ECL biosensor possesses excellent selectivity, accuracy, and stability for VEGF 165 detection in a linear range of 2 pg mL −1 to 2 ng mL −1 with a detection limit of 0.68 pg mL −1 . In addition, this assay has been successfully applied to the determination of VEGF 165 in serum samples.
Schematic representation of the electrochemiluminescence sensor based on a g-C3N4/PDDA/CdSe nanocomposite, which can be determined in the concentration of vascular endothelial growth factor in serum.
研究领域:
生物化学
·
分析化学
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纳米技术
·
生物传感器
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DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Long Wu,Shuhong Zhou,Yonghuan Yun,Lin Zhu,Bei Li,Weimin Zhang
Based on the exchange of the DNA duplex-quadruplex, a multifunctional Pb(II) ion probe was fabricated, in which Pb(II) ion-driven DNA duplexes act as a bridge to link CdSe/ZnS-luminol and Fe 3 O 4 nanoparticles . As Pb(II) ion owns a strong binding capacity for G-quadruplex (G4), it can unwind the DNA duplex and release its complementary strand. In this strategy, three detection modes, chemiluminescence (CL), fluorescence (FL) assay and colorimetric assay (CA), can be realized via DNA duplex bridged CdSe/ZnS and Fe 3 O 4 nanocomposites . Amongst, FL assay shows the best detection performance, and it exhibits a linear range of 10 nM to 10 µM, as well as the limit of detection (LOD) with 1.63 nM (n = 3, ± 3.5%). In the selective analysis, Pb(II) ion can be specifically detected in the nine different interfering metal ions . Besides, the magnetic probe requires only one “mixing and separation” operation and greatly improves the detection efficiency. The three assays can be combined as one method to achieve a simple and rapid feature. Such a three-in-one analytical platform, therefore, can serve as a powerful tool for selective, accurate and sensitive detection of Pb(II) ion.
研究领域:
生物化学
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分析化学
·
纳米技术
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产品关联
DOI
高影响因子
Frontiers in Chemistry
·
2019
·
IF 3.782
Hong Sihui,She Yongxin,Cao Xiaolin,Wang Miao,He Yahui,Zheng Lufei,Wang Shanshan,Abd El-Aty A. M.,Hacimüftüoglu Ahmet,Yan Mengmeng,Wang Jing
In the present study we have developed a direct competitive CdSe/ZnS quantum dot (QD) fluorescence assay based on micro-array-imprinted membranes for the determination of triazophos in cabbage and apple. The imprinted membranes were directly synthesized on the surface of a 96-well plate by thermal polymerization using triadimefon as the dummy template. Under optimal conditions, the assay showed an excellent linear response over the concentration ranges of 0.1–10,000 μg L−1 with a good coefficient of determination (R2= 0.982). The sensitivity (IC50) and limit of detection (LOD, expressed as IC15) of the developed assay were 3.63 mg L−1 and 0.31 μg L−1, respectively. The applicability of the developed approach was tested for detecting triazophos in incurred samples. The method showed excellent recoveries (109.6–118.9%) and relative standard deviations (RSDs) between 9.9 and 19.5%. The obtained results correlated well with those obtained by LC-MS/MS (R2= 0.9995). The competitive assay using CdSe/ZnS QDs as fluorescence-labeled probe showed good sensitivity, steady and fast response, and excellent anti-interference ability compared to conventional fluorescence-quenching methods. Finally, the feasibility of the proposed methodology was successfully applied for detection of triazophos in real samples.
研究领域:
分析化学
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食品安全
·
环境科学
✓ 已验证
DOI
PubMed
高影响因子
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
·
2017
·
IF 1.86
Shengyu Zhang,Liuwan Zhao,Nanqin Qiu,Yanjun Liu,Bohui Xu,Hongyan Zhu
Hypoxia, an outstanding characteristic of various solid tumors, has been considered a critical factor of aggressive tumor phenotypes, poor clinical prognosis, and increased expression of the multidrug-resistant gene. Therefore, it is critical to develop a drug delivery system to enhance the delivery effect of the antitumor drug in the hypoxic tumor. We constructed two types of tumor targeting micelles based on chitosan and evaluated their properties in targeting hypoxic tumors. Chitosan-based micelles consisted of a hydrophobic group octyl group, a hydrophilic polyethylene glycol, tumor targeting ligands glucosamine or folic acid, and a transmembrane peptide 9-d-arginine. The molecular structure, morphology, size distribution, zeta potential, and biosafety of two micelles were characterized. Oil-soluble CdSe quantum dots were used as a fluorescent probe to evaluate the hypoxic tumor cell targeting properties of the micelles. Moreover, HepG2 human hepatocellular carcinoma cells and HeLa human cervical carcinoma cells were used as in vitro models. We demonstrated that, under hypoxic conditions, two chitosan micelles showed better targeting ability to HepG2 and HeLa cells, which enhanced the effect of antitumor drugs by specifically targeting transport in hypoxic tumors. Therefore, chitosan micelles may be a potential drug delivery system that can be used to deliver antitumor drugs to hypoxic tumors.
研究领域:
药剂学
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肿瘤学
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材料科学
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纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL LETTERS
·
2025
·
IF 1.8
Junting Li,Hailing Zheng,Hao Du,Chao Zhang,Jiancong Fu,Xinyu Wen,Lin Ma,Yang Zhou,Zhiqin Peng,Bing Wang
Obtaining information about proteins is crucial for exploring the origin and distribution of ancient silk. However, complex burial environments often cause degradation of silk. During archaeological excavations, these silk residues were usually in the form of fibers, fabric fragments or coatings, and in some cases even degrade into peptides that are difficult to find with the naked eye. In this work, a fluorescent immunochromatographic strip assay based on CdSe/ZnS quantum dots, which have high fluorescence quantum yield, good stability, and wide range of excitation wavelengths, was developed for on-site detection of silk residues. The results showed that the strip assay possessed good specificity and recognized silk fibroin within 15 min with a limit of detection (LOD) of 42.66 ng/mL. The strip assay was also successfully utilized for the analysis of ancient silk residues and assisted in obtaining information on residual proteins. In addition, the strip assay is portable, easy to use, and suitable for batch screening and testing. Therefore, this study provides a new strategy for rapid identification of silk residues.
研究领域:
考古科学
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生物考古学
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蛋白质组学
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分析化学
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免疫学
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材料科学
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现场快速检测
✓ 已验证
产品关联
DOI
高影响因子
Analytical Methods
·
2019
·Vol. 12
·期 4
·491-498
·
IF 2.378
Zhang-Jin He,Tian-Fang Kang,Li-Ping Lu,Shui-Yuan Cheng
In this study, a novel electrochemiluminescence (ECL) biosensor based on a CdSe@CdS quantum dot (QD)-functionalized MoS2-modified electrode was developed for the sensitive detection of mercury ions. Polycationic poly(diallyldimethylammonium chloride) (PDDA) and negatively charged QDs were adsorbed on the surface of MoS2, in sequence, to form the QD–PDDA–MoS2 composites, which were employed as matrices for immobilizing thymine-rich DNA sequences (DNA1). The gold nanoparticles (AuNPs) were combined with another type of thymine-rich DNA sequences (DNA2) and glucose oxidase (GOD) to prepare the GOD–AuNP–DNA2 conjugates. The composites were characterized via UV-visible absorption spectroscopy, fluorescence and transmission electron microscopy. A thymine–Hg2+–thymine complex was formed through Hg2+ mismatching with DNA1 and DNA2. GOD was, therefore, modified onto the electrode surface. GOD catalyzed the reduction of dissolved oxygen by glucose to produce hydrogen peroxide, which was a co-reactant of the QDs. The electrochemiluminescence signal of the biosensor increased linearly with the increase in the Hg2+ concentration over the range from 1.0 × 10−12 to 1.0 × 10−6 M with a detection limit of 1 × 10−13 M. The reproducibility, stability and specificity of the biosensor was also studied. The biosensor was used to determine Hg2+ in a real water sample and satisfactory results were obtained.
研究领域:
分析化学
·
环境科学
·
生物传感技术
✓ 已验证
DOI
高影响因子
Journal of Environmental Sciences
·
2017
·
IF 2.865
Jiangsu Wen,Changchang Ma,Pengwei Huo,Xinlin Liu,Maobin Wei,Yang Liu,Xin Yao,Zhongfei Ma,Yongsheng Yan
Visible-light-driven photocatalysis as a green technology has attracted a lot of attention due to its potential applications in environmental remediation. Vesicle CdSe nano-semiconductor photocatalyst are successfully prepared by a gas template method and characterized by a variety of methods. The vesicle CdSe nano-semiconductors display enhanced photocatalytic performance for the degradation of tetracycline hydrochloride, the photodegradation rate of 78.824% was achieved by vesicle CdSe, which exhibited an increase of 31.779% compared to granular CdSe. Such an exceptional photocatalytic capability can be attributed to the unique structure of the vesicle CdSe nano-semiconductor with enhanced light absorption ability and excellent carrier transport capability. Meanwhile, the large surface area of the vesicle CdSe nano-semiconductor can increase the contact probability between catalyst and target and provide more surface-active centers. The photocatalytic mechanisms are analyzed by active species quenching. It indicates that h + and O 2 − are the main active species which play a major role in catalyzing environmental toxic pollutants . Simultaneously, the vesicle CdSe nano-semiconductor had high efficiency and stability.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2020
·
IF 4.939
Changlin Li,Yanfang Wang,Shangrong Chen,Wei Zhang,Zi Wang,Zhongyu Hou
The erosion issue of ZnO nanorod arrays (NRAs) film is the major obstacle in surface sensitization of ZnO NRAs grown on Zn foil substrate for photoelectrochemical (PEC) applications. In this paper, PEC performance of ZnO NRAs grown on Zn foil substrate was greatly enhanced by coating ZnSe and CdSe on the surface of ZnO NRAs. Dense ZnO NRAs were in - situ grown on seed-free Zn foil substrate in a NH 3 ·H 2 O and NaOH hydrothermal system. ZnSe/CdSe co-sensitized ZnO heterostructures were then successfully synthesized using ZnO NRAs as precursors by two successive in - situ ion exchanges without damaging Zn foil and ZnO NRAs film. To obtain optimal photoconversion efficiency, anion exchange time and temperature were optimized. ZnO/ZnSe/CdSe heterostructures with optimized structure were shown as a layer of compact ZnSe/CdSe nanofilm conformally and uniformly coated on ZnO NRAs, which leads to efficient separation of photogenerated carriers , significant enhancement in visible-light absorption, and excellent PEC performance with photocurrent density of 3.008 mA/cm 2 (−0.2 V vs . Ag/AgCl) and photoconversion efficiency of 1.99% (0.418 V vs . RHE in polysulfide electrolyte solution), 27.55 and 40.61 times higher than those of ZnO NRAs, respectively.
研究领域:
材料科学
·
光电化学
·
纳米技术
·
能源材料
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DOI
高影响因子
危险品化学品经营许可证（带存储）