RENEWABLE ENERGY
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2022
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IF 8.634
Shanshan Tu,Xiaojie Yu,Qinghua Ji,Qiannan Ma,Cunshan Zhou,Li Chen,Clinton Emeka Okonkwo
With the deepening of the research on the conversion of cellulose biomass to furfural, there is no green and efficient method to separate sugars and 5-HMF. This study utilized a thermoreversible aqueous two-phase system (ATPS) coupled with tetrabutylammonium bromide ([N 4444 ]Br)- based deep eutectic solvents (DES) and inorganic salts for separating glucose and 5-HMF. The thermal characteristics of DESs were analyzed by thermogravimetry (TGA) and differential scanning calorimetry (DSC). The thermoreversible phase behavior of ATPS was determined by phase diagram. Furthermore, the process factors were optimized, such as the type and concentration of DES and phosphate, the temperature, and the time of ATPS were investigated, to maximize the separation of glucose and 5-HMF. Finally, the ATPS was a successful integrated catalytic reaction of glucose involving CrCl 3 and 5-HMF separation. The results showed that the ATPS consist of 30 wt% [N 4444 ]Br-EG and 25 wt% K 2 HPO 4 had the most efficient extraction rate, 5-HMF reached 96.0 ± 0.6%, and mainly existed in the DES phase, while glucose was enriched in salt phase, and the extraction rate reached 99.9 ± 0.03%. And the 5-HMF yield reached 25.6 ± 1.1% in the production separation integrated platform. This thermoreversible ATPS may provide a guide for the effective extraction of furfural from biomass-derived glucose.
研究领域:
生物化学
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绿色化学
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高影响因子
Foods
·
2022
·Vol. 11
·期 5
·657
·
IF 5.561
Huiyu Hu,Yuting Wang,Yousheng Huang,Yanpeng Yu,Mingyue Shen,Chang Li,Shaoping Nie,Mingyong Xie
Maillard reaction during food processing contributes to the formation of some unpleasant heat-induced toxicants including advanced glycation end products (AGEs) and 5-hydroxymethylfurfural (HMF). The current study prepared butter cookies fortified with two dietary natural antioxidants (catechins and curcumin) and two dietary hydrocolloids (pectin and chitosan), and investigated their effects on formation of free Nε-(carboxymethyl)lysine (CML)/Nε-(carboxyethyl)lysine (CEL), protein-bound CML/CEL and HMF and on the sensory qualities of butter cookies. Meanwhile, three typical α-dicarbonyl compounds were also determined to identify possible correlations between α-dicarbonyl intermediates and formation of these harmful heat-induced products in butter cookies. Experimental data showed that catechin exhibited the strongest inhibitory effects on formation of AGEs and HMF, but its addition would impair the color and taste of cookies. On the other hand, chitosan was not so effective in inhibiting AGEs and HMF as compared to catechin, but its addition could increase the sensory qualities of butter cookies.Keywords:advanced glycation end products;5-hydroxymethylfurfural;butter cookies;natural antioxidants;hydrocolloids
研究领域:
食品科学
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营养学
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DOI
PubMed
高影响因子
APPLIED SURFACE SCIENCE
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2022
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IF 7.392
Fuyuan Qi,Weiping Yang,Haochen Yu,Lan-Lan Lou,Shuangxi Liu,Kai Yu
The electronic interaction between metal and support plays a significant role in varying catalytic activity of oxide-supported metal catalysts for the aerobic oxidation of biomass-based alcohols and aldehydes. Employing Y 3+ -doped ceria supported Pt catalysts, Pt/Ce 1-x Y x O 2-δ , different interfacial atomic structures, including Pt/Ce-Vo(-Ce) 2 , Pt/Y-Vo(-Ce) 2 , Pt/Ce-Vo(-Y) 2 , and Pt/Y-Vo(-Y) 2 (Vo represents an oxygen vacancy), were created in this work to modulate the interfacial electron transfer capacity. The results of experimental and theoretical investigations showed that the Pt/Y-Vo(-Ce) 2 interfacial structure owned the highest electron transfer capacity from Pt to the support, resulting in more Pt δ+ /Y-Vo(-Ce) 2 sites. Accordingly, the catalyst Pt/Ce 0.75 Y 0.25 O 2-δ owning the largest amount of Pt δ+ /Y-Vo(-Ce) 2 sites exhibited notably promoted catalytic activity for the oxidation of 5-hydroxymethylfurfural (HMF) toward 2,5-furandicarboxylic acid (FDCA), affording a complete conversion of HMF and 96.6% yield of FDCA in 6 h. This work provided a facile and versatile strategy to modulate the electron transfer capacity of oxide supported metal catalysts by manipulating the interfacial atomic structure for promoting their activities in various catalytic oxidation reactions.
研究领域:
材料科学
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催化化学
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DOI
高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
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2023
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IF 3.1
Xiang Shuang,Guo Yong,Liu Xiaohui,Wang Yanqin
The interface between Au and support has attracted extensive interest because of its unique catalytic ability for hydrogen activation in catalytic hydrogenation/hydrogenolysis reactions. Herein, we create the Au-CoO-O V interface in the 1.0%Au/Co 3 O 4 -Rod-250 catalyst, which could dissociate H 2 via the heterolytic way to yield rich hydride species and achieve excellent catalytic performance in the hydrogenolysis of biomass-derived 5-hydroxymethylfurfural (HMF) to 2,5-dimethylfuran (DMF). The XRD and HRTEM analyses show that Au nanoparticles are uniformly dispersed on CoO-O V surface and in situ DRIFTS spectra show the enhancement of heterolytic dissociation of hydrogen (signals of Au—D and O—D vibration) compared with bare CoO (Co 3 O 4 -Rod-250). This work provides insights for fabricating highly active Au-support catalysts for catalytic hydrogenation/hydrogenolysis reactions.
研究领域:
化学工程
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催化材料科学
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DOI
高影响因子
CATALYSIS LETTERS
·
2025
·Vol. 155
·期 8
·1-12
·
IF 2.4
Ma Xueqin,Shen Liuwei,Shi Gaolei,Zhang Xingguang
The selective oxidation of 5-hydroxymethylfurfural (HMF) to value-added products plays an important role in biomass catalytic transformation, which essentially depends upon design of highly efficient and selective catalysts. This study aims to identify contributions of silanols (Si-OH groups) on Ag/USY catalysts to regulating catalytic performances in selective oxidation of HMF to HMFCA (5-hydroxymethyl-2-furancarboxylic acid), by means of aluminium tri-sec-butoxide (AlBO) modification to suppress Si-OH groups of USY and 2,6-di-tert-butylpyridine (2,6-DTBPy) selective poison to shield Brønsted acid sites in the reaction system. The catalysts are characterized by XRD, BET, TEM, XPS and FT-IR to examine the crystal structures, surface areas, porosity, morphology, Ag distribution, chemical states, and surface adsorptive properties. The HMF conversion (44-49.2%) slightly changes with increasing AlBO content, whereas the HMFCA selectivity gradually goes down from 56.2 to around 22.1% and the levulinic acid (LA) selectivity minorly raises from 5.6 to 12.8%. The production of LA originates from enhanced Brönsted acid sites after AlBO modification, and the decline of HMFCA selectivity is principally attributed to the suppression of Si-OH groups that weakens the interaction between HMF reactants and catalysts. This work provides new insights into the role of surface modification in tailoring metal and zeolite-based catalysts for organic conversions. Graphical
研究领域:
催化化学
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生物质转化
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化学反应工程
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材料科学
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有机化学
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DOI
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
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2021
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IF 4.952
Zhisheng Zhou,Miao Zhu,Guowen Zhang,Xing Hu,Junhui Pan
5−Hydroxymethyl−2−furaldehyde (5-HMF) in dairy food products generated via Maillard reaction may bring health risks. Herein, the interaction of 5-HMF with β-casein (β-CN) and its influences on the structure and function of β-CN were investigated. 5-HMF was found to quench the inherent fluorescence of β-CN by a static mode and the binding constant was in the order of magnitude of 10 4 L mol −1 . Thermodynamic analysis indicated that hydrophobic forces played the major role in the interaction. The results of synchronous and three-dimensional fluorescence revealed that 5-HMF changed the microenvironment of tyrosine and tryptophan residues and interfered the stability of the polypeptide backbone structure in β-CN. Molecular docking revealed that 5-HMF bound to the hydrophobic cavity of β-CN mainly interacting with the amino acid residues Pro196, Val155, Leu163, Phe157 and Leu192. The binding of 5-HMF with β-CN caused partial unfolding of β-CN conformation, resulting in the increase in surface hydrophobicity and emulsifiability, and decrease in emulsification stability of β-CN, thereby reducing the solubility of β-CN. The study might facilitate the comprehensive understanding of 5-HMF affecting the structure and functional properties of β-CN.
研究领域:
食品科学
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生物化学
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分子生物学
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DOI
高影响因子
Acta Pharmaceutica Sinica B
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2021
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IF 11.614
Ping-Ting Xiao,Zhi-Shen Xie,Yu-Jia Kuang,Shi-Yu Liu,Chun Zeng,Ping Li,E-Hu Liu
The mammalian target of rapamycin (mTOR)-sterol regulatory element-binding proteins (SREBPs) signaling promotes lipogenesis. However, mTOR inhibitors also displayed a significant side effect of hyperlipidemia. Thus, it is essential to develop mTOR-specific inhibitors to inhibit lipogenesis. Here, we screened the endogenous inhibitors of mTOR, and identified that FKBP38 as a vital regulator of lipid metabolism. FKBP38 decreased the lipid content in vitro and in vivo via suppression of the mTOR/P70S6K/SREBPs pathway. 3,5,6,7,8,3ʹ,4ʹ-Heptamethoxyflavone (HMF), a citrus flavonoid, was found to target FKBP38 to suppress the mTOR/P70S6K/SREBPs pathway, reduce lipid level, and potently ameliorate hyperlipidemia and insulin resistance in high fat diet (HFD)-fed mice. Our findings suggest that pharmacological intervention by targeting FKBP38 to suppress mTOR/P70S6K/SREBPs pathway is a potential therapeutic strategy for hyperlipidemia, and HMF could be a leading compound for development of anti-hyperlipidemia drugs.
研究领域:
药理学
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代谢学
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脂质生物学
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药物发现
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DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
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2026
·
IF 13.2
Bo Zhang,Xinlei Ma,Jing Zhang,Neyha Rubab Syed,Leilei Dai,Roger Ruan
This study presents a novel strategy of piezocatalysis driven by ball milling (BM) for the anaerobic oxidation of biomass-derived 5-hydroxymethylfurfural (HMF) to high-value 2,5-diformylfuran (DFF) with simultaneous hydrogen (H₂) production. A rationally designed Schottky heterojunction (CS/MB) composed of 1D CdS nanorods (CS) and 2D MoB MBene nanosheets (MB) is synthesized, demonstrating strong interfacial coupling and efficient electron transfer (from CS to MB). The unique piezocatalytic system operates under mild mechanical energy input (600 rpm), achieving an exceptional 80.36% HMF conversion with 78.00% DFF yield (97.07% selectivity) and an H 2 evolution rate of 0.147 μmol/(mg catalyst ·h). This substantial enhancement, which achieved a 2.7-fold increase in DFF formation kinetics and a 1.8-fold boost in H₂ generation over pristine CS, signifies a clear breakthrough in piezocatalytic systems for coupled biomass oxidation and proton reduction. Mechanistic investigations via ESR spectroscopy and DFT calculations reveal that carbon-centered radicals mediate the selective oxidation pathway, while the Schottky junction at the CS/MB interface enhances charge separation, thereby suppressing recombination. By replacing conventional thermal/chemical inputs with mechanical activation, this work pioneers a self-sustaining bio-refinery paradigm where piezoelectric polarization and catalytic active sites cooperate as a unified energy-harvesting reactor. This strategy demonstrates a promising potential pathway for simultaneously advancing green chemical synthesis and renewable energy production.
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高影响因子
CATALYSIS LETTERS
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2026
·Vol. 156
·期 9
·261
·
IF 2.5
Su Qiqi,Dai Wanrong,Liu Meijun,Cheng Mengyu,Dai Chunyan,Li Yafei
The rational design of non-noble metal catalysts relies on a deep understanding of the structure-performance relationship. Herein, we investigate the influence of pyrolysis temperature (800–1100 °C) on Co–N/C catalysts derived from ZnCo-ZIF for the aerobic oxidation of 5‑hydroxymethylfurfural (HMF) to 2,5‑furandicarboxylic acid (FDCA). A volcano‑shaped dependence of FDCA yield on pyrolysis temperature is observed, with the catalyst pyrolyzed at 1000 °C (Co–N/C-1000) delivering complete HMF conversion and 98.0% FDCA yield within 4 h under optimized conditions (110 °C, 2 MPa O 2 ). Multi-technique characterization reveals a temperature-driven evolution of Co species: from atomically dispersed Co–N x sites at 800–900 °C, to a bimodal configuration comprising abundant Co–N x together with a small amount of metallic Co 0 nanoparticles at 1000 °C, and finally to large Co aggregates at 1100 °C. The optimal catalytic performance at 1000 °C is thus attributed to this unique coexistence. Kinetic analysis confirms the consecutive pathway HMF → HMFCA → FFCA → FDCA with FFCA→FDCA as the rate‑determining step. Notably, the optimal catalyst maintains 96.8% FDCA yield under industrially relevant 5 wt% HMF concentration. This work provides insights into the structure-performance relationship of Co–N/C catalysts and a rational strategy for designing efficient non-noble metal catalysts for biomass conversion. Graphical
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高影响因子
RARE METALS
·
2026
·Vol. 45
·期 9
·e70493
·
IF 12.1
Pei Li,Wei Quan,Weikang Ling,Yushun Han,Jimei Li,Guanlong Wang,Jiliang Ma,Runcang Sun
en This link goes to a English section zh This link goes to a Chinese section Photocatalytic H 2 evolution coupled with biomass upgrading offers a sustainable route for clean energy conversion and high-value chemical synthesis. Herein, an in situ grown S-scheme MnS/MnB-MBene heterojunction (denoted as SM x ) was fabricated via alkaline etching of Mn 2 AlB 2 followed by controlled sulfurization. This strategy effectively removes the Al layer, exposes abundant active sites, and simultaneously establishes an intimate S-scheme heterojunction that promotes spatial charge separation and boosts redox kinetics. The optimized SM6 catalyst achieves a remarkable H 2 evolution rate of 1704.81 μmol g −1 h −1 , along with 99.16% conversion of 5-HMF and 79.42% selectivity toward 5-hydroxymethyl-2-furoic acid (HMFCA). These values correspond to 15.97-fold and 7.7-fold enhancements in H 2 evolution compared to pristine Mn 2 AlB 2 and MnB-MBene, respectively. The spatially separated redox sites—MnB-MBene as oxidation sites and MnS as reduction sites—enable efficient, site-specific catalytic reactions, significantly enhancing overall performance. This study provides a rational design strategy for MBene-based heterojunctions and offers insights into advancing biomass photorefinery coupled with solar fuel production. 摘要 en This link goes to a English section zh This link goes to a Chinese section 光催化析氢耦合生物质高值化转化, 为清洁能源转化与高附加值化学品合成开辟了一条可持续路径。本文通过对Mn 2 AlB 2 进行碱刻蚀并结合可控硫化处理, 原位制备出S型异质结MnS/MnB-MBene复合材料 (记作SM x )。该制备策略可有效去除铝原子层, 暴露出大量活性位点, 同时构建紧密的S型异质结, 进而促进载流子空间分离、加快氧化还原反应动力学过程。经优化的SM6催化剂表现出优异性能:光催化析氢速率达1704.81 μmol g −1 h −1 , 5-羟甲基糠醛(5-HMF)转化率为99.16%, 对5-羟甲基糠醛酸(HMFCA)的选择性达79.42%。相较于纯Mn 2 AlB 2 与MnB-MBene, 其析氢活性分别提升15.97倍和7.7倍。体系中氧化还原位点实现空间分离:MnB-MBene作为氧化活性位点, MnS作为还原活性位点, 可实现位点专一的高效催化反应, 大幅提升整体催化性能。本研究为基于MBene的异质结催化剂提供了合理的设计思路, 也为光驱动生物质精炼耦合太阳能燃料制备领域的发展提供了理论参考。
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高影响因子
CELLULOSE
·
2025
·
IF 4.8
Xuan Xiang-Tao,Zhang Hui,Yao Jia-Le,Miao Ya-Ping,Fan Wei,Dong Xiang-Zhi,Dai Chen-Min,Miao Jiao-Jiao
Photoreforming cellulose to simultaneously produce 5-hydroxymethylfurfural (5-HMF) and hydrogen represents a promising strategy for harnessing solar energy. However, the development of highly efficient photocatalysts for this reaction remains a challenge, and the influence of cellulose’s crystalline structure on conversion efficiency is not well understood. In this study, a Pt-modified g-C 3 N 4 –Bi 3 TiNbO 9 heterojunction photocatalyst was synthesized to explore the photocatalytic reforming of four crystalline forms of cellulose. The results demonstrate that the crystalline structure of cellulose significantly affects hydrogen and 5-HMF production, with the order of activity being cellulose III > IV > II > I. Among the cellulose types tested, cellulose III exhibited the highest performance, achieving 51.8 μmol g⁻ 1 h⁻ 1 of hydrogen and 113.4 μmol g⁻ 1 h⁻ 1 of 5-HMF, surpassing the yields from cellulose I, II, and IV when using the Pt 1.0 –g-C 3 N 4 –Bi 3 TiNbO 9 (2:1) heterojunction. Additionally, a lower degree of polymerization of cellulose was found to favor the coproduction of hydrogen and 5-HMF, as it enhances the breakdown of cellulose via reactive species. Factors such as cellulose powder size, solution pH, and catalyst-cellulose interactions were also shown to influence the yields. Density functional theory (DFT) calculations revealed an electron migration of 0.019684e between the O 2 p and Bi 6 p orbitals of Bi 3 TiNbO 9 (220) and the C 2 p and N 2 p orbitals of g-C 3 N 4 , confirming interfacial electron transfer. The calculated adsorption energies followed the trend: cellulose IV (− 1.72 eV) > I (− 1.73 eV) > II (− 1.94 eV) > III (− 2.07 eV), consistent with experimental results, except for cellulose IV. Graphical abstract
研究领域:
能源科学
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材料科学
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化学工程
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Yuan-Bao Zhang,Qun-Xing Luo,Mei-Heng Lu,Dan Luo,Zhong-Wen Liu,Zhao-Tie Liu
The hollow-structured porous aromatic polymers (H-PAP) with cavity diameter from 228 ± 11 to 464 ± 15 nm were controllably prepared through surface coating and template-etching method under scalable synthesis conditions from standard scale to 20-fold scale-up. It is found that the fill factor ( f ) of reactor is an important parameter for determining the scalability of synthesis. Benefiting from the favorable textural properties, chemical and thermal stability, surface hydrophobicity and π electrons, the well-developed H-PAP as adsorbent was investigated in selective adsorption of 5-hydroxymethylfurfural (HMF) under static batch mode from the single-component and multi-component aqueous solutions. The H-PAP shows an exclusive adsorption for HMF, without adsorption of fructose, levulinic acid (LA) and formic acid (FA), and can be recycled three times without significant decrease in adsorption capacity. Structure-performance relationship points out that the apparent amount of HMF adsorbed on H-PAP is related to micropore surface area, micropore volume and cavity diameter, while HMF selectivity depends on surface hydrophobicity. In the case of HMF adsorption from the real reaction mixture of acid-catalyzed fructose dehydration, the HMF constituent with high purity (ca.94.4%) can be recovered. Combining the adsorption isotherms with DFT calculation reveals adsorption mechanism that HMF adsorption on H-PAP proceeds initially via π–π stacking interaction, and then assembles into regular array around spherical surface to form monolayer coverage following modified Langmuir model, and finally diffuses into interior cavity until adsorption saturation.
研究领域:
化学工程
·
材料科学
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DOI
高影响因子
危险品化学品经营许可证（带存储）