ANALYTICAL CHEMISTRY
·
2019
·
IF 6.35
Xiaoding Xu,Lei Zhao,Qilu Xue,Jinkun Fan,Qingqing Hu,Chu Tang,Hongyan Shi,Bo Hu,Jie Tian
Cell detection is of great significance for biomedical research. Surface enhanced Raman scattering (SERS) has been widely applied to the detection of cells. However, there is still a lack of a general, low-cost, rapid, and sensitive SERS method for cell detection. Herein, a dynamic liquid SERS platform, which combines label-free SERS technique with soft tubular microfluidics for cell detection, is proposed. Compared with common static solid and static liquid measurement, the dynamic liquid SERS platform can present dynamical mixing, precise control of the mixing time, and continuous spectra collection. By characterizing the model molecules, the proposed dynamic liquid SERS platform has successfully demonstrated good stability and repeatability with 1.90% and 4.98% relative standard deviation (RSD), respectively. Three cell lines including one normal breast cell line (MCF-10A) and two breast cancer cell lines (MCF-7 and MDA-MB-231) were investigated in this platform. 270 cell spectra were selected as the training set for the classification of the models based on the K-Nearest Neighbor (K-NN) algorithm. In three independent experiments, three types of cells were identified by a test set containing 180 cell spectra with sensitivities above 83.3% and specificities above 91.6%. The accuracy was 94.1 ± 1.14% among three independent cell identifications. The dynamic liquid SERS platform has shown higher signal intensity, better repeatability, less pretreatment, and obtainment of more spectra with less time consumption. It will be a powerful detection tool in the area of cell research, clinical diagnosis, and food safety.
研究领域:
生物医学工程
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分析化学
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细胞生物学
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临床诊断
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DOI
PubMed
高影响因子
JOURNAL OF ELECTRONIC MATERIALS
·
2019
·Vol. 48
·期 11
·7068-7075
·
IF 1.676
Li Shuhui,Zhou Ying,Cui Lijun,Ge Zhenhua,Feng Jing
In 2 O 3 (ZnO) k superlattice ceramics are promising oxide thermoelectric materials, as superlattice interfaces are effective in scattering phonons and filtering low-energy electrons to decrease thermal conductivity and improve the figure of merit ( ZT ) value. In this work, homologous compounds were prepared by solid-state reaction method using ZnO and In 2 O 3 as raw materials. Phase purity and crystal structure were characterized by x-ray diffraction, revealing that In 2 O 3 (ZnO) k crystallizes in an R3 m space group for odd k values and P6 3 /mmc for even k values. The study of thermoelectric (TE) properties showed that as k increased, the thickness of InO(ZnO)
+ 3
also increased, while the electrical conductivity, thermal conductivity, Seebeck coefficient, power factor and ZT value were all decreased. In 2 O 3 (ZnO) 3 samples obtained a maximum power factor of 651 μ W m −1 K −2 at 973 K, and also achieved a maximum ZT value of 0.24 at 973 K.
研究领域:
材料科学
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凝聚态物理
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能源转换技术
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DOI
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2026
·
IF 19.7
Yuran Li,Yu Zhang,Yuting Lin,Guangyan Xu,Ruixiang Xu,Wei Su,Tingyu Zhu
A K-Nd/Al 2 O 3 catalyst achieves a COS capacity of 1.46 g/g under H 2 S/O 2 co-feeding. • K modulates Nd Lewis acidity and facilitates the dissociative activation of H 2 O. • Synergistic K and Nd sites enable the formation of key *HOCOS and *HSCOO intermediates. • Adaptive Nd-O x sites, enhanced by K-induced effects, promote H 2 S desorption. The development of efficient alumina-based catalysts for carbonyl sulfide (COS) hydrolysis remains a significant challenge, as their application in real blast furnace gas is largely hindered by insufficient activity and poor long-term durability. Here, K-Nd/Al 2 O 3 maintains nearly complete COS conversion for 20 h at 120 °C and achieves a cumulative COS conversion capacity of 1.46 g/g under a simplified H 2 S/O 2 -containing atmosphere. Comprehensive characterization reveals that K-Nd co-modulation tailors acid-base site distribution, preserving active sites. Aberration-corrected HAADF-STEM and XAFS analyses confirm that Nd is predominantly atomically dispersed, existing as isolated, low-coordinated Nd-O x single-sites. During reaction, the Nd-O coordination number increases from 4.2 to 8.0 without aggregation, demonstrating reaction-induced reconstruction of the first coordination shell. Surface characterization, in-situ DRIFTS, and DFT calculations further show that K enhances surface electron density and fine-tunes Nd Lewis acidity, promoting H 2 O dissociation and nucleophilic *OH attack on COS, stabilizing *HOCOS and *HSCOO intermediates while facilitating H 2 S desorption. The synergy between Nd-O x centers and K-induced electronic regulation reconcile durable COS hydrolysis under harsh conditions. Download: Download high-res image (225KB) Download: Download full-size image
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DOI
高影响因子
THERMOCHIMICA ACTA
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2017
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IF 2.236
Ying Zhang,Shi Zhang,Sanguo Peng,Maogang He
Diffusivity of redox shuttle additive in solvent plays an important role in the design of Li-ion battery. As redox shuttle additive, 10-methylphenothiazine (MPT) can give good overcharge protection in LiFePO4-based Li-ion cells, therefore diffusion coefficient of MPT in solvent needs to be known. A different data processing method based on optical digital interferometry is put forward to determine diffusion coefficient in this work. This method is verified by KCl aqueous solution and the relative standard uncertainty of diffusion coefficient is about 2.3%. The diffusion coefficients of MPT in dimethyl carbonate (DMC) from 288.15 K to 313.15 K at several concentrations are measured and the corresponding calculation equation of diffusion coefficient is presented.
研究领域:
化学工程
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电化学
·
材料科学
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产品关联
DOI
高影响因子
APPLIED ORGANOMETALLIC CHEMISTRY
·
2024
·
IF 3.7
Yi Jing Jia,Jin Quan Tao,Hao Ran Liu,Wen Bin Huang,Rongpeng Yao,Miaomiao Niu,Rongrong Li,Qiang Wei,Ya Song Zhou
To enhance the CO 2 hydrogenation activity and low-carbon olefin selectivity of Fe-based catalysts, a strategy involving the use of metal promoters to modulate the structure of active metal centers in catalyst preparation was proposed. The incipient wetness impregnation method was used to introduce modifying agents K and/or Co into the Fe/Al 2 O 3 catalyst. Characterization techniques such as XRD, BET, SEM, HRTEM, H 2 -TPR, XPS, CO 2 -TPD, NH 3 -TPD, and TG were employed to investigate the effects of the modifying agents on the dispersion, reducibility, electronic properties, and acid–base properties of active metal species. Furthermore, the influence of K and Co modification on the CO 2 hydrogenation activity and low-carbon olefin selectivity of Fe/Al 2 O 3 catalysts was explored. The results revealed that the introduction of K generated more basic sites and electron-rich active metal centers in the catalyst, facilitating the adsorption and activation of CO 2 , while suppressing the hydrogenation of olefins and the formation of methane, thus improving the selectivity towards low-carbon olefins. Co promoter facilitated the dispersion of Fe species, exposing more active sites and enhancing the FTS reaction activity, leading to more CO being converted into C 2+ hydrocarbon products. Under the synergistic effect of K and Co, the CO 2 conversion activity of the Fe-based catalyst significantly increased, achieving a CO 2 conversion rate of 37%, while the selectivity towards C 2 -C 4= increased to 31.9%.
研究领域:
催化化学
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材料科学
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产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Yaru Wang,Ruyue Su,Jingyi Chen,Wenqing Wang,Xueqin Zhang,Hao Xu,Rujie He
With 5G and millimeter-wave technologies evolving rapidly, the high communication frequency leads to high integration and miniaturization of the Luneburg lens (LL). In this paper, a miniaturized K-band flat LL with 0.95MgTiO 3 –0.05CaTiO 3 (95MCT) ceramic was designed and successfully printed by vat-photopolymerization 3D printing . Optimal 3D printing parameters and thermal treatment processes of 95MCT ceramic were investigated. The as-prepared 95MCT ceramic showed excellent properties: a density of 3.40 g/cm 3 , a high flexural strength of 81.78 MPa, a dielectric constant of 17.7, and a remarkably low dielectric loss value of 4.56 × 10 -4 . Based on the 95MCT ceramic, a flat LL with a diameter of 40 mm and thickness of 6 mm was printed with sophisticated metastructure. While miniaturization was accomplished with a high degree of dimensional compression, the printed flat LL showed a maximum gain enhancement over 5 dBi. Thus, this study provides a novel viewpoint on the fabrication of microwave dielectric ceramic and miniaturized ceramic radio frequency (RF) devices with complex structures.
研究领域:
材料科学
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电子工程
·
通信技术
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产品关联
DOI
高影响因子
LUMINESCENCE
·
2023
·Vol. 38
·期 9
·1562-1571
·
IF 2.9
Fadong Li,Yaosen Ye,Ruirui Cui,Jun Zhang,Cong Xu,Hui Xu,Gangyi Zhang,Chaoyong Deng
A series of Mn 4+ -doped and Mn 4+ ,K + -co-doped Ba 2 LaTaO 6 (BLT) double-perovskite phosphors was synthesized using a high-temperature solid-state reaction. The phase purity and luminescence properties were also studied. The optimum doping concentration of Mn 4+ and K + was obtained by investigating the photoluminescence excitation spectra and photoluminescence emission spectra. The comparison of BLT:Mn 4+ phosphors with and without K + ions shows that the photoluminescence intensity of K + -doped phosphors was greatly enhanced. This is because there was a charge difference when Mn 4+ ions were doped with Ta 5+ ions in BLT. Mn 4+ –K + ion pairs were formed after doping K + ions, which hinders the nonradiative energy transfer between Mn 4+ ions. Therefore, the luminescence intensity, quantum yield, and thermal stability of phosphors were enhanced. The electroluminescence spectra of BLT:Mn 4+ and BLT:Mn 4+ ,K + were measured. The spectra showed that the light emitted from the phosphors corresponded well with chlorophyll a and phytochrome P R . The results show that the BLT:Mn 4+ ,K + phosphors had good luminescence properties and application prospects and are ideal materials for plant-illuminated red phosphors.
研究领域:
材料科学
·
植物学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2025
·
IF 2.1
Honglin Xu,Ruilin Wang,Yongsheng Deng,Guofeng Dou,Xinyu Wang
The stable phase equilibrium of the reciprocal quaternary system of Na+, K+//VO3–, Cl––H2O at 298.15 K was investigated by an isothermal solution equilibrium method. The equilibrium liquid phase solubility data and physical property data [density (ρ), refractive index (nD), and pH] were determined, and the composition of the equilibrium solid phase was verified by X-ray diffraction. The phase diagram and physical property–composition diagrams were constructed based on the equilibrium solubility data and physical property data. The phase diagram contains three invariant points, seven isothermal univariant curves, and five crystalline phase regions. The study found that this quaternary system belongs to a complex system with the presence of the double salts. By comparing the experimental results with literature data, it was confirmed that at 298.15 K, the chemical formulas of the complex salt which formed by the quaternary system Na+, K+//VO3–, Cl––H2O were consistent with the complex salt chemical formula (Na2mKn(VO3)2m+n) proposed by the Druzynski group, thus verifying the reliability of this experiment. The results of this study will provide new experimental data for the thermodynamics of vanadium–water systems.
研究领域:
物理化学
·
无机化学
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产品关联
DOI
高影响因子
FLUID PHASE EQUILIBRIA
·
2013
·
IF 2.379
Zhongbin Meng,Yonghong Hu,Yumei Kai,Wenge Yang,Zheng Cao,Fei Shen
The solubility of thiomalic acid was measured in methanol, ethanol, 2-propanol, 1-butanol, acetone, acetonitrile, and ethyl acetate in the temperature range between 278.15 K and 333.15 K under atmospheric pressure by gravimetric method. The solubility of thiomalic acid in those selected solvents increased with increasing temperature. The solubility data were correlated using the simplified molecular thermodynamic equation, the modified Apelblat equation and the semi-empirical Buchowski–Ksiazczak λh equation. The thermodynamic properties of the solution process, including the Gibbs energy, enthalpy, and entropy were calculated by the van’t Hoff analysis and the Gibbs equation. The experimental results showed that acetonitrile had the potential as the better solvent in the recrystallization process of thiomalic acid.
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产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2022
·
IF 3.119
Yongjun Wu,Yong Xie,Hongwei Shi
In this work, the mole fraction solubility of rhein in 12 pure solvents including methanol, ethanol, n-propanol, isopropyl alcohol, 1-butanol, isobutyl alcohol, 1,4-dioxane, 2-butanone, cyclohexanone, acetone, acetonitrile, and N,N-dimethylformamide (DMF) at the temperature range from 283.15 K to 323.15 K was studied. The largest mole fraction solubility is observed in 1,4-dioxane (1.450 × 10–3) at 323.15 K, followed by in DMF (6.964 × 10–4), cyclohexanone (4.026 × 10–4), acetone (2.432 × 10–4), 2-butanone (2.009 × 10–4), 1-butanol (5.646 × 10–5), isopropyl alcohol (5.082 × 10–5), n-propanol (4.552 × 10–5), isobutyl alcohol (3.375 × 10–5), ethanol (3.798 × 10–5), methanol (3.083 × 10–5), and acetonitrile (1.655 × 10–5). The solubility first increases and then decreases with the increase of carbon chain length in alcohols. Through the analysis of 1,4-dioxane and DMF properties, the solute molecules should belong to weakly polar compounds, which is also reflected in the alcohols. However, for ketone solvents, the solubility decreases with the decrease of dipolarity/polarizability. This may be caused by the joint action of the solvent cavity term effect and hydrogen bonds. The largest relative average deviation (RAD) from the data is no more than 5%, which suggests that the calculated solubility data using the modified Apelblat model and λh model agreed very well with the experimental ones for each solvent. Compared with the values reported by Cheng and co-workers, there is an increase of 87.61-fold of solubility between 1,4-dioxane and acetonitrile at 323.15 K. Hence, the solubility data achieved in the present work could be very useful for the purification and crystallization of rhein.
研究领域:
药理学
·
物理化学
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产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2023
·
IF 2.6
Xudong Yu,Xia Feng,Shan Feng,Yun Peng,Ying Zeng
The solid–liquid equilibria of the quinary system Li+, K+, Mg2+//Cl–, B4O72––H2O at 323.2 K were investigated by the isothermal dissolution method. The solubility, refractive index, and density of the system were determined, and the corresponding space phase diagram, planar projection diagram, water content diagram, and density/refractive index vs composition diagrams saturated with MgB4O7 are constructed based on the experimental data. The result shows that there are double salts of lithium carnallite (LiCl·MgCl2·7H2O) and carnallite (KCl·MgCl2·6H2O) formed in the system. The space phase diagram consists of five invariant points, 16 isothermal solution curves, and eight crystalline regions (Li2B4O7·3H2O, K2B4O7·4H2O, KCl, MgB4O7·9H2O, KCl·MgCl2·6H2O, MgCl2·6H2O, LiCl·MgCl2·7H2O, LiCl·H2O). Under the saturation of salt MgB4O7, the crystalline region of Li2B4O7·3H2O is the largest in the planar projection diagram of this system, and the solubility of LiCl is the largest. A comparison of planar projection diagrams (under the saturation of salt MgB4O7) of the system at 273.2 and 323.2 K shows that the crystallization regions of Li2B4O7·3H2O, KCl·MgCl2·6H2O, LiCl·MgCl2·7H2O, and LiCl·H2O increase along with the temperature, while those of K2B4O7·4H2O and KCl decrease. The results show that low temperature is conducive to the extraction of potassium in the form of K2B4O7·4H2O and KCl and has less entrainment loss; high temperature is beneficial to the precipitation of Li2B4O7·3H2O.
研究领域:
化学工程
·
材料科学
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产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF LEGAL MEDICINE
·
2024
·Vol. 138
·期 4
·1323-1328
·
IF 2.2
Yu Zhonghao,Zhao Erjuan,Shi Qing,Yuan Yuhao,Ma Jinghong,Zhou Luwang,Duan Yijie,Zhou Yiwu
Brodifacoum exerts its antagonistic effect against the metabolism of vitamin K, an essential component in the synthesis of blood coagulation factors. This effect ultimately hinders the blood’s capacity to clot effectively, rendering it a commonly employed rodenticide. Instances of lethal poisonings are exceedingly rare owing to expeditious medical intervention and treatment. Within this report, we present a case of brodifacoum-induced homicide, wherein the patient exhibited distinct clinical examinations and symptoms. Moreover, the patient’s blood sample exhibited a noteworthy brodifacoum concentration of 0.681 µg/mL even after a period of 43 days following the incident of poisoning. Although an autopsy was not conducted due to religious restrictions, we endeavor to reasonably deduce the cause of death and furnish corroborative evidence for clinical diagnosis, treatment, and forensic examination in instances involving brodifacoum poisoning.
研究领域:
医学
·
毒理学
·
法医学
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DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）