COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING
·
2024
·
IF 8.1
Xiaolu Chen,Mingen Ding,Chuan Yang,Wei Zhang,Hao Deng,Dawei Yan,Haohao Ren,Yonggang Yan
Developing biomaterials with high osteogenic activity and mechanical properties comparable to cortical bone is critical for repairing load-bearing bone defects. Poly(amino acid) (PAA), with its excellent biocompatibility and collagen-like structure, shows great potential as a biomaterial. In this study, PAA was synthesized via melt copolymerization, and bioactive glass (BG) with high osteogenic activity was uniformly dispersed in the PAA matrix using solution co-deposition. High-strength quartz fibers (QF) were added to form PAA/BG/QF composites. Amongst, the P/20BG-20QF composite exhibited bending strength (174.7 MPa), bending modulus (8.8 GPa), compressive strength (135.1 MPa) and compressive modulus (3.7 GPa) comparable to the lower range of cortical bone. In vitro analysis showed low degradation (1.1 %), optimal pH (7.2) and no surface cracks, indicating lasting stability. Cell compatibility tests and osteogenic gene expression further confirmed the potential of P/20BG-20QF composites as implants for low-load-bearing bone defect repair.
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Zhenglin Chen,Jiaqi Yang,Zhicheng Du,Jiansong Ji,Likun Zhang,Haifei Guan,Zhengyang Lei,Xiaopeng Zhang,Canhui Yang,Ying Zhu,Qianhui Sun,Lulu Xu,Ke Lin,Yuchen Wang,Chuhui Wang,Chong Zhang,Dongmei Yu,Peiwu Qin,Can Yang Zhang
In the realm of flexible wearable electronics and interactive technologies, the adhesive and touch-sensing properties of materials play a crucial role, especially soft ionic conductors. However, these materials face several challenges in practical application, including structural damage, loss of functionality, and device stratification, particularly in extreme environments. To address this, a novel multifunctional organic hydrogel, termed PC-OH, was designed and prepared to enhance its performance. The hydrogel exhibits self-adhesion, self-healing, anti-freezing, anti-drying, and conductive capabilities. It demonstrates outstanding self-adhesive properties on skin surfaces under air (approximately 967 J/m2) or underwater (approximately 428 J/m 2 ) conditions, with high transparency (visible light transmittance of 87 %), anti-freezing capability (−60 °C), anti-drying capability (60 °C), rapid self-healing in air or water (within 4 s), long-term stability over a wide temperature range (−20 °C to 60 °C for up to 7 days), high extensibility (up to ∼1700 % at 60 °C and ∼1200 % at −20 °C), and conductivity over a broad temperature range (ionic conductivity of 1.93 S m −1 at 60 °C and 3.13 × 10 -3 S m −1 at −30 °C). Based on these properties of PC-OH hydrogel, we constructed a capacitive touch system to demonstrate its practical application. The touch panel features high stretchability, transparency, anti-freezing, anti-dehydration, self-healing, and self-adhesive human–machine interface capabilities, enabling integration with the skin under abnormal temperature and humidity conditions. Tasks such as writing text, drawing graphics, and playing electronic games validated the significant potential of the hydrogel in touch panels, providing a solution to long-standing issues of adhesion and tactile sensing.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
·
IF 9.136
Gaocan Qi,Kaiyue Guo,Jie Yang,Yuhang Wang,Ziyu Wang,Zhihao Yuan
The practical application of filter membranes for oil–water separation requires high efficient, large flux and excellent stability. Hydrogel membrane with superhydrophilicity and underwater superoleophobicity has been considered as an ideal material for efficient separation of oil–water mixture. However, hydrogel materials are generally fragile and easy to dehydrate. In this work, inorganic CuO oriented-rods framework was used to support water-adsorbent polyacrylic acid (PAA) resin for constructing superhydrophilic-superoleophobic composite hydrogel membrane. The as-prepared composite membrane displayed stable underwater superoleophobicity during swelling-drying cycles and abrasion test. In “bottom-injection” filter apparatus, the CuO@PAA membrane exhibited high separation efficiencies, above 99.90%, for kerosene-water, hexadecane-water, soybean oil–water and rapeseed oil–water mixtures with water penetration fluxes larger than 5700 L•m −2 •h −1 . The excellent separation efficiency and flux were capable of maintaining for 200 separation processes. This work paved the way for designing and constructing economical and practical oil–water separation equipment for industrial application.
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Materials
·
2018
·Vol. 11
·期 2
·247
·
IF 2.467
Quanguo He,Jun Liu,Jing Liang,Xiaopeng Liu,Du Tuo,Wen Li
Solubility parameter-dependent drug releasing property is essential in practical drug delivery systems (DDS), and how to combine magnetic nanoparticles(NPs) and suitable polymer coating towards DDS is always a crucial and valuable challenge in biomedical application. Herein, a controllable drug delivery model with a surface having a chemically tunable solubility parameter is presented using hollow magnetite/polyacrylic acid (Fe3O4/PAA) nanocomposites as nanocarrier towards DDS. This composite is prepared by simply coating the modified hollow Fe3O4with PAA. The coating amount of PAA onto the surface of Fe3O4(measured by TGA) is about 40% (w/w). Then, Rhodamine 6G (R6G) is selected as model drug in drug delivery experiment. The efficiency of drug loading and drug release of these Fe3O4/PAA nanocarriers are evaluated under various temperature, solvent and pH values. As a result, the best drug releasing rate was achieved as 93.0% in pH = 7.4 PBS solution after 14 h. The releasing efficiency is 86.5% in acidic condition, while a lower releasing rate (30.0%) is obtained in aqueous solution, as different forms (polyacrylic acid and polyacrylate) of PAA present different solubility parameters, causing different salt and acid effects in various solvents, swelling property of PAA, and binding force between PAA and R6G. Therefore, by changing the solubility parameter of coating polymers, the drug delivery properties could be effectively tuned. These findings prove that the DDS based on magnetic particle cores and polymer encapsulation could efficiently regulate the drug delivery properties by tuning surface solubility parameter in potential cancer targeting and therapy.Keywords:hollow Fe3O4NPs;Fe3O4/PAA composite NPs;solubility parameter;controlled release;drug delivery systems
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PROCESS BIOCHEMISTRY
·
2024
·
IF 3.7
Pengpeng Cheng,Zhenyu He,Bo Liu,Jinmei Wang,Chuyue Zhang,Lan Tang,Lihua Du,Yuan Lu,Zhimin Ou
Nano-bienzyme conjugates (nano-BECs) for catalysing one-pot reactions can simplify the reaction process and improve the efficiency of biocatalytic reactions. In this work glucose dehydrogenase (GDH) and Candida parapsilosis secondary alcohol dehydrogenase (CpSADH) were immobilised with polyacrylic acid (PAA) to form two types of PAA-based nano-BECs (2-S, 2-P), which achieved in situ regeneration of NADH for the production of chiral alcohols in oil-water biphasic systems, such as the key chiral pharmaceutical intermediate of ( S )-1-(3-trifluoromethylphenyl)ethanol (( S )-TMPE). At a substrate concentration of 100 mM 3-trifluoromethylacetophenone (TMAP), the conversion catalyzed by nano BEC was 98.2 % in dipentyl phthalate-phosphate buffer biphasic system. In contrast, the conversion was only 39.5 % and 38.9 % in the PB buffer and 8.4 % and 7.7 % in dipentyl phthalate system. The experiments on kinetic constants demonstrated that the catalytic efficiencies (K cat /K m ) of nano-BECs (2-S, 2-P) were enhanced by 6.7-fold and 7-fold, respectively, compared to free CpSADH. Additionally, nano-BECs showed stronger coenzyme regeneration ability. Under optimal reaction conditions, nano-BECs achieved 96.2 % conversion of TMAP to ( S )-TMPE in an organic-buffer system with e.e. > 99.6 % at 300 mM substrate concentration. This research expands the potential applications of polymers and proteins, and offers valuable insights into the synergistic effects of PAA on bienzyme catalytic systems in biocatalysis.
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Journal of Materials Chemistry B
·
2017
·Vol. 5
·期 21
·3919-3926
·
IF 4.543
Yan Xing,Qin Gao,Yanmin Zhang,Le Ma,Kang Yong Loh,Mingli Peng,Chao Chen,Yali Cui
Nanocomposites are emerging complex nanoscale materials composed of different phases that have received considerable attention as a result of their widespread impact on a myriad of fields. Having said this, it is important to recognize that poor colloidal stabilities in physiological media and non-specific interactions with biology are key limitations prohibiting their successful translation into the development of practical technologies with real impact. Herein, PAA coated Au/Fe3O4 composite magnetic nanoparticles (NPs) with monodispersity and high biostability were engineered for the development of a highly sensitive C-reactive protein (CRP) chemiluminescence immunoassay (CLIA), based on the horseradish peroxidase (HRP)–luminol–H2O2 system. In addition, zwitterionic glycerophosphoryl choline (GPC) was employed as a co-blocking agent to reduce the nonspecific adsorption. This assay reports a limit of detection (LOD) of 2.5 pM with high reproducibility verified clinically and demonstrating improved progress towards translation into clinics.
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MACROMOLECULAR BIOSCIENCE
·
2026
·Vol. 26
·期 8
·e70242
·
IF 4.2
Linhan Hu,Zheng Yang,Xinwei Tao,Bowen Ren,Tianle Zhou,Jianliang Li,Huaping Tan,Xiaohong Hu
Hydrogel-based dressings are widely used in wound healing. Herein, we report a polyacrylic acid (PAA)/polyvinyl alcohol (PVA) composite hydrogel fabricated via self-catalyzed free radical polymerization, with borax serving as the reinforcing phase. Meanwhile, metal-ligand coordination bonding between tannic acid (TA) and Fe 3 + further elevates the crosslinking density of the hydrogel network. Magnetic chitosan microspheres (MCMs) were synthesized by emulsion cross-linking and loaded with two antibacterial agents, namely tetracycline hydrochloride (TH) and berberine hydrochloride (Bbh). The incorporation of MCMs into the hydrogel matrix resulted in the development of a multifunctional composite hydrogel suitable for wound dressing applications. Results demonstrated that the composite hydrogel containing a specific concentration of 4‰ (w/v) borax and 20 mg/mL MCMs exhibited superior performance, including enhanced mechanical strength, improved responsiveness, sustained drug release, and potent antibacterial efficacy. The core novelty of this work lies in the synergistic integration of borax-based mechanical reinforcement, MCM-mediated dual drug loading and sustained release, and the self-catalyzed polymerization system. This innovative structural and functional collaboration effectively optimizes the mechanical stability of the hydrogel dressing and achieves synergistic antibacterial and intelligent responsive therapeutic performances, providing a reliable and high-efficiency candidate for advanced wound care and next-generation wound dressing applications.
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POLYMERS FOR ADVANCED TECHNOLOGIES
·
2025
·Vol. 36
·期 1
·e70031
·
IF 3.4
Xiaotian Wang,Yeerken Aheyeli-kai,Huakun Ying,Jiangli Lin,Yulu Luo,Hongying Ma,Zhongyang Li,Zhen Su
Triphenylmethane dyes have a wide range of applications in textiles, pharmaceuticals, food, and other fields. Malachite green (MG), fuchsin acid (FA), and crystalline violet (CV) were typical representatives of triphenylmethane dyes, and they are carcinogenic and mutagenic to aquatic organisms and environment. However, they need to be separated and enriched for their accurate quantification due to their low content. Therefore, it is important to develop a rapid and accurate enrichment method to monitor these dyes in aquatic systems for human health. In this paper, a novel QuEChERS adsorbent porous ZIF67/PAA/PES composite microspheres were prepared and applied for the rapid adsorption of triphenylmethane dyes in wastewater and fish samples, which improved the adsorption capacity and the analytical sensitivity of the targets. The experimental results demonstrated that the porous ZIF-67/PAA/PES composite microspheres exhibited excellent selective adsorption capacity of MG, FA, and CV, and after six adsorption–desorption cycles, the material adsorption amount can reach more than 90% of its original adsorption amount in wastewater. In addition, the porous ZIF67/PAA/PES composite microspheres were applied as QuEChERS adsorbents for the enrichment of MG and CV dyes in fish, and the adsorption rates of the dyes were 99.11% and 99.03%, with the RSDs of 1.58% and 1.27%, respectively. The limits of detection were 0.0093 and 0.0127 mg/L for MG and CV. Through the Langmuir adsorption isotherm models to predict the MG, FA, and CV of the maximum adsorption capacity were 5417.3622, 2119.9011, and 1654.1026 mg/g, respectively. Thus, the novel porous ZIF67/PAA/PES composite microspheres are more advantageous as QuEChERS adsorbents for sample pre-treatment and have very important research significance.
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Advanced Optical Materials
·
2025
·
IF 7.2
Zi-Rong Zhou,Hong-Fei Li,Zi-Hao Liao,Zhe-Xun Zhu,Feng Wang
Smart luminescent materials capable of time-resolved dynamic fluorescence color transitions hold immense potential for advanced information encryption and anti-counterfeiting technologies in the emerging digital era. However, achieving precise control over wide-range fluorescence color modulation remains a significant challenge. In this study, a novel reverse sustained-release strategy is presented to fabricate CsPbBr 3 @PAA perovskite quantum dots (QDs), where ultra-small CsPbBr 3 QDs within quantum confinement size (QCS) are confined within a polyacrylic acid (PAA) matrix. Initially, the CsPbBr 3 @PAA QDs exhibit blue-violet fluorescence in toluene due to the quantum confinement effect. Upon exposure to hydrous alcohol, the PAA matrix enables a controlled, reverse release of CsPbBr 3 QDs into the solvent, triggering a morphological transition from sub-nanometer QDs to nanoblocks exceeding the QCS. This structural evolution induces a dynamic time-dependent fluorescence shift from blue-violet to green, spanning five visually distinct colors (blue-violet, blue, cyan, turquoise, and fluorescent green) across the CIE chromaticity diagram. By leveraging this unique time-resolved color transition mechanism, programmable information encryption and dynamic fluorescent patterning with temporal precision are demonstrated. This work not only advances the design of stimuli-responsive luminescent materials but also provides a versatile platform for next-generation optical security systems
研究领域:
材料科学
·
纳米技术
·
光学安全
·
荧光光谱学
·
化学工程
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Carbon Energy
·
2024
·
IF 19.5
Yuanyuan Zhao,Lei Gao,Qiurui Wang,Qiang Zhang,Xiya Yang,Jingwei Zhu,Hao Huang,Jialong Duan,Qunwei Tang
Suppressing nonradiative recombination and releasing residual strain are prerequisites to improving the efficiency and stability of perovskite solar cells (PSCs). Here, long-chain polyacrylic acid (PAA) is used to reinforce SnO 2 film and passivate SnO 2 defects, forming a structure similar to “reinforced concrete” with high tensile strength and fewer microcracks. Simultaneously, PAA is also introduced to the SnO 2 /perovskite interface as a “buffer spring” to release residual strain, which also acts as a “dual-side passivation interlayer” to passivate the oxygen vacancies of SnO 2 and Pb dangling bonds in halide perovskites. As a result, the best inorganic CsPbBr 3 PSC achieves a champion power conversion efficiency of 10.83% with an ultrahigh open-circuit voltage of 1.674 V. The unencapsulated PSC shows excellent stability under 80% relative humidity and 80°C over 120 days.
研究领域:
材料科学
·
太阳能
·
纳米技术
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Zheng Zhang,Jinfeng Zhang,Zhihua Zhang,Xiao Du,Xiaogang Hao,Xiaowei An,Guoqing Guan,Jun Li,Zhong Liu
A novel physically blended polyvinylidene fluoride (PVDF) and polyacrylic acid (PAA) composite binder enhanced LiMn 2 O 4 /C (carbon black) film based electrode was successfully fabricated, and applied in an electrochemically switched ion exchange (ESIX) process for selective extraction of Li + from high Mg/Li ratio brine. The multifunctional composite binder system enabled the obtained LiMn 2 O 4 /C/PVDF- b -PAA film coated electrode to exhibit superior mechanical, hydrophilic and electrochemical properties compared with the LiMn 2 O 4 /C/PVDF film coated electrode. Based on the density functional theory (DFT) calculations, the ion exchange interaction between H + of –COOH groups in PAA and Li + facilitated the transport of Li + at the electrode interface, which enhanced lithium extraction performance of the film coated electrode. For treating the simulated brine (Mg/Li: ∼500), the intercalation capacity of Li + was about 15.1 mg g −1 , and the total extraction efficiency of lithium reached up to 62.8% after two electrochemical intercalation tests. Moreover, the film coated electrode displayed excellent selectivity towards Li + ions even in pre-treated actual brine (Mg/Li: ∼292.2). The Mg/Li mass ratio in the recovery solution could decrease to 0.46, and the calculated Li + /Mg 2+ separation coefficient reached as high as 631.08. In particular, the highly stable and scalable electroactive film could be prepared effectively, thus increasing its applicability. It is expected that such a LiMn 2 O 4 /C/PVDF- b -PAA film coated electrode could be a promising candidate for the selective extraction of Li + from high Mg/Li mass ratio brines.
研究领域:
材料科学
·
电化学工程
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高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Jinpeng Hu,Dezhi Zhang,Wenbao Li,Yan Li,Guorong Shan,Min Zuo,Yihu Song,Ziliang Wu,Lie Ma,Qiang Zheng,Miao Du
Marine biofouling, resulting from the adhesion of marine organisms to ship surfaces, has long been a significant issue in the maritime industry. In this paper, we focused on utilizing soft and hydrophilic hydrogels as a potential approach for antifouling (AF) coatings. Acrylic acid (AA) with a polyelectrolyte effect and N-(3-sulfopropyl)-N-(methacryloxyethyl)-N,N-dimethylammonium betaine (SBMA) with an antipolyelectrolyte effect were selected as monomers. By adjusting the monomer ratio, we were able to create hydrogel coatings that exhibited low swelling ratio in both fresh water and seawater. The Al(OH)3 nanoparticle, as a physical cross-linker, provided better mechanical properties (higher tensile strength and larger elongation at break) than the chemical cross-linker through the dynamic coordination bonds and plentiful hydrogen bonds. Additionally, we incorporated trehalose into the hydrogel, enabling the repair of the hydrogel network through covalent-like hydrogen bonding. The zwitterion compound SBMA endowed the hydrogel with excellent AF performance. It was found that the highest SBMA content did not lead to the best antibacterial performance, as bacterial adhesion quantity was also influenced by the charge of the hydrogel. The hydrogel with appropriate SBMA content being close to electrical neutrality exhibits the strongest zwitterionic property of PSBMA chains, resulting in the best antibacterial adhesion performance. Furthermore, the pronounced hydrophilicity of SBMA enhanced the lubrication of the hydrogel surface, thereby reducing the friction resistance when applied to the hull surface during ship navigation.
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