IONICS
·
2014
·Vol. 20
·期 9
·1225-1234
·
IF 1.836
Ren Shitong,Zheng Tao,Zhou Qian,Zhang Liaoyun,Li Huayi
Hyperbranched star polymer HBPS-(PPEGMA)
x
was synthesized by atom transfer radical polymerization (ATRP) using hyperbranched polystyrene (HBPS) as macroinitiator and poly(ethylene glycol) methyl ether methacrylate (PEGMA) as monomer. The structure of the prepared hyperbranched star polymer was characterized by 1 H NMR, ATR-FTIR, and GPC. Polymer electrolytes based on HBPS-(PPEGMA)
x
, lithium salt, and/or nano-TiO 2 were prepared. The influences of lithium salt concentration and type, nano-TiO 2 content, and size on ionic conductivity of the obtained polymer electrolytes were investigated. The results showed that the low crystallinity of the prepared polymer electrolyte was caused by the interaction between lithium salt and polymer. The addition of TiO 2 into HBPS-(PPEGMA)
x
/LiTFSI improved the ionic conductivity at low temperature. The prepared composite polymer electrolyte showed the highest ionic conductivity of 9 × 10 −5 S cm −1 at 30 °C when the content of TiO 2 was 15 wt% and the size of TiO 2 was 20 nm.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2017
·
IF 3.981
Qiaochu Zhang,Meiling Qi,Jinliang Wang
This work reports oligothiophene-functionalized truxene-based stationary phases (TTT, TDT and TFT) with a unique star-shaped π-conjugated architecture for gas chromatographic (GC) separations. They exhibited medium polarity and column efficiency of 3340–3760 plates/m determined by naphthalene at 120 °C. Among them, the TTT stationary phase displayed advantageous resolving capability over the TDT and TFT phases for a wide ranging analytes from apolar to polar, particularly for structural and positional isomers, including alcohols, phenols, halogenated and alkylated benzenes and naphthalenes. Moreover, the TTT column exhibited good thermal stability and repeatability with relative standard deviation (RSD) values of 0.02%–0.07% for run-to-run, 0.10%–0.53% for day-to-day and 2.1%–2.9% for column-to-column, respectively. In addition, it was applied for the determination of isomer impurities in real samples, proving its good potential for practical GC analysis.
研究领域:
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2023
·
IF 9.9
Qian Ma,Rong Qiang,Yulong Shao,Xiao Yang,Rui Xue,Bowen Chen,Yi Chen,Shijiang Feng
The demand of microwave absorption materials (MAMs) with unique morphologies and electromagnetic (EM) balance has become necessary in recent years. Due to the ease of synthesis and tunable structure, metal–organic frameworks (MOFs) are widely used for this special MAMs. In this study, a new three-dimensional hybrid MOF is proposed that is co-doped with six equally branched star morphologies. The Co-C composite has the same six-branched morphology as that of the precursor. When the EM wave is incident, this special structure makes it easier for the EM wave to enter the material vertically due to the expansion of the incident surface, which is effective in adjusting the transmission path of the electron and the reflection and distribution of the EM wave. Because of the special morphology and magneto-dielectric synergy, the Co-C composite shows a minimum reflection loss ( R Lmin ) of −48.5 dB at 11.0 GHz at an absorption thickness of 3.0 mm, with a microwave absorption bandwidth (EAB) of 6.1 GHz. This research provides a practical guidance for preparing the MAMs of special star structure.
研究领域:
材料科学
·
电磁学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2015
·
IF 5.056
Fangli Deng,Xiaoen Wang,Dan He,Ji Hu,Chunli Gong,Yun Sheng Ye,Xiaolin Xie,Zhigang Xue
A novel microporous polymer electrolyte (MPE) based on poly (vinylidene fluoride) (PVDF)/poly (ethylene oxide) (PEO) star polymer was prepared by a phase inversion technique. The effects of PEO chain length of star polymer and temperature on ionic conductivity of MPE were investigated. The results showed that the ionic conductivity increased generally with the chain length of star polymer arms without any abrupt change. Effects of star polymer mass fraction on electrolyte uptake and leakage were also discussed. The distribution of holes and connectivity was improved with star polymer mass fraction increased, thus resulted in a high ionic conductivity (3.03×10 −3 S cm −1 ) exhibited at room temperature. Moreover, the electrochemical stability window was observed above 5.0 V (vs. Li/Li + ). All these results showed that this MPE could be served as a good candidate for lithium ion batteries .
研究领域:
材料科学
·
能源科学
✓ 已验证
DOI
高影响因子
Soft Matter
·
2012
·Vol. 8
·期 23
·6364-6370
·
IF 4.39
Fenggui Chen,Chunliang Li,Xiaoyan Wang,Guangming Liu,Guangzhao Zhang
In the present study, by use of the atom transfer radical polymerization (ATRP) method, we have prepared well-defined 6-arm star-shaped poly[2-(dimethylamino)ethyl methacrylate] (PDEM) and poly(acrylic acid) (PAA) containing a fluorescent triphenylene core and have studied the pH and ion-species sensitive fluorescence properties of such two star polyelectrolytes. The results obtained by analytical ultracentrifugation indicate that the star PDEM molecules will aggregate together as the pH increases over the pKa but the star PAA molecules will keep a monomeric state over the whole pH range. For both PDEM and PAA, the fluorescence intensity decreases with increasing pH, indicating that the fluorescence intensities of PDEM and PAA are dominated by aggregation induced fluorescence quenching and the chain conformation controlled nonradiative relaxation, respectively. This suggestion is further confirmed by the fact that the star PDEM molecules can form excimers at high pHs and no excimer emission peak can be observed for the star PAA molecules. In the studies of ion-specific fluorescence properties at different pH, for both of the two polyelectrolytes, the ion specificity is determined by the counterion condensation for the charged chains, whereas nonelectrostatic ion adsorption governs the specific ion effect for the uncharged chains.
研究领域:
高分子化学
·
物理化学
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2020
·Vol. 55
·期 22
·9525-9537
·
IF 3.553
Bai Ting,Zhu Bobo,Du Zhaoyi,Shi Junling,Shao Dongyan,Kong Jie
The combination therapy by using two or more chemotherapeutic agents with different action mechanisms has shown to be an attractive strategy for cancer treatment with synergistic therapeutic effects, and also the side effects reduction by one agent replacing part of another one. In this work, an amphiphilic star copolymer with an H40 hyperbranched polyester as the core and poly(ε-caprolactone)-poly(2-dimethylaminoethylmethacrylate) copolymer incorporated with the fluorescent DTM groups as the arms were designed to encapsulate the model anti-cancer drug, doxorubicin (DOX), and a novel potential agent, avasimibe (Ava). Those two drugs could inhibit DNA replication and block acyl-CoA cholesterol acyltransferase-1 (ACAT-1) to induce the cell apoptosis, respectively. The model drugs could be easily loaded into the micelles with a high total drug-loading content toward 24.6% by altering the feeding drug ratios. Three molar ratios (DOX:Ava = 3:1, 1:1, and 1:3) of the drug-loaded micelles were prepared and evaluated for in vitro antitumor efficacy. Results showed that the micelles with 1:1 ratio exhibited the best synergistic cytotoxic activity against both K562 and HeLa cells. Furthermore, the dual-drug combination with efficient anticancer performance was also confirmed by live/dead staining, apoptosis, and cell cycle analysis. Moreover, the internalization of these dual-drug-loaded micelles could be monitored by fluorescent DTM groups and DOX. All these results suggested that the addition of Ava could cut down the dose of DOX to reduce its potential side effects and the co-delivery system could be a promising approach for an effective combination chemotherapy.
研究领域:
药学
·
肿瘤学
·
生物材料
✓ 已验证
DOI
高影响因子
JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS
·
2016
·
IF 1.568
Fangyuan Guo,Wei Zhang,Xiaohong Pei,Xia Shen,Qinying Yan,Hanbing Li,Junxian Yun,Gensheng Yang
Effective local delivery methods for sustained and stable release of protein drugs are urgently needed. Biodegradable elastomers based on star-shaped polycyclic esters have received attention for their drug-loading and drug-release kinetics. However, the long degradation periods resulting from their strong lipophilicity greatly hinder their application. In this study, we synthesized new cross-linked elastomers based on methyl-acrylic-star-poly(ϵ-caprolactone-co-d,l-lactide) cyclic ester and methyl-bi-acrylic-poly(ϵ-caprolactone-b-poly(ethylene glycol)-b-ϵ-caprolactone) with different molecular weights; determined their physical, thermal, and morphological characteristics; and studied their in vitro degradation and release of bovine serum albumin and recombinant human interleukin 2. Elastomer hydrophilicity improved with the introduction of methyl-bi-acrylic-poly(ϵ-caprolactone-b-poly(ethylene glycol)-b-ϵ-caprolactone), and a shorter degradation period (~25 weeks) was achieved. Additionally, the degradation rate could be adjusted by varying the composition of methyl-bi-acrylic-poly(ϵ-caprolactone-b-poly(ethylene glycol)-b-ϵ-caprolactone) to directly influence the degree of swelling, cross-linking density, and sol content of the elastomer. The controlled rate of bovine serum albumin and recombinant human interleukin 2 release increased with a larger degree of swelling, higher sol content, and lower cross-link density of the elastomers. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide analysis showed good biocompatibility. These results suggest that these new elastomers are potential candidates for carrier materials in controlled, implantable delivery systems for protein drugs and other biomedical applications.
研究领域:
生物材料学
·
药物递送系统
·
组织工程
✓ 已验证
DOI
高影响因子
PLANT DISEASE
·
2026
·
IF 2.8
Hongyan Zhang,Wenwen Li,Wenjun Song,Chao Wang,Shandong Xu,Aining Li,Yonglin Wang
Fungicides currently used to control poplar Cytospora canker (PCC), mainly caused by Cytospora chrysosperma, exhibit variable field efficacy, require high application frequency, pose resistance risks, and impose considerable environmental burdens. In this study, we developed a six-arm star polymer (SSP)-based nanocarrier system to deliver benomyl and carbendazim, aiming to enhance the control efficacy against C. chrysosperma. The SSP formed stable complexes with benomyl and carbendazim through hydrogen bonding and Van der Waals interactions, reducing their particle sizes from 864.36 nm to 14.76 nm and 2725.44 nm to 33.16 nm, respectively. Nanoagents demonstrated markedly enhanced antifungal efficacy over standalone fungicides. Specifically, SSP-benomyl at 3.8 mg/L (IC50 of benomyl) reduced the colony diameter of C. chrysosperma from 80 mm to 23 mm, while SSP-carbendazim at 2.6 mg/L (IC50 of carbendazim) reduced it from 80 mm to 29 mm. Besides high inhibition of fungal growth and control efficiency of PCC, these SSP-based nanoagents exhibited potential disease prevention. Our results provide a nanopesticide delivery system of SSP to manage PCC.
✓ 已验证
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Qiang Peng,Xiaomin Luo,Jiarong Su,Yongguang Bi,Fansheng Kong,Zhong Wang,Shaofan Tan,Junyong Zhang
Star anise essential oil (SAEO) has garnered significant attention for its potent bioactivities. However, the instability and poor water solubility of SAEO limit its application in the food and pharmaceutical industries. To overcome these challenges and improve bioavailability, we encapsulated SAEO within β-cyclodextrin (β-CD) using a saturated aqueous solution method. Characterization techniques including Fourier transform infrared spectroscopy , Scanning electron microscopy, X-ray diffraction, and Thermogravimetric-differential scanning calorimetry confirmed the successful formation of SAEO and β-CD inclusion complex (SAEO-IC) with good thermal stability . The inclusion complex had a yield of 63.18 ± 3.18% and an oil content of 9.32 ± 0.36%. In vitro digestion studies revealed the stability of SAEO-IC in gastric conditions, with the primary release of active ingredients occurring in the intestine. Moreover, the encapsulation process preserved the antioxidant properties of SAEO and demonstrated enhanced antimicrobial and anti-tumor activity, suggesting that SAEO-IC has the potential to serve as a natural antimicrobial and anticancer agent .
研究领域:
食品科学
·
药学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
POLYMER INTERNATIONAL
·
2016
·Vol. 65
·期 5
·551-558
·
IF 2.414
Shihai Wang,Yu Zhou,Bo Zhuang,Peng Zheng,Hongxiang Chen,Tongcun Zhang,Haiman Hu,Dengcheng Huang
To obtain polyurethane micelles with excellent stability as a drug delivery carrier, star-shaped amphiphilic block polyurethane (SAPU) was successfully synthesized by the ‘arm-first’ method, using methoxypoly(ethylene glycol) and poly(ε-caprolactone) diol as soft segments, hexamethylene diisocyanate as hard segments and pentaerythritol as the core. The structure of the SAPU was characterized by Fourier transform infrared spectroscopy, 1 H NMR spectroscopy and gel permeation chromatography. The micellization behaviour and micelle properties of SAPU were measured by the pyrene fluorescence probe technique, 1 H NMR, SEM and dynamic light scattering. The results indicated that SAPU could self-assemble to form nanomicelles in aqueous solution and that the micelles showed excellent stability upon dilution and storage. Indometacin as a model drug could be incorporated into SAPU micelles and be released sustainedly. Meanwhile, the hydrophilic segment content and the molecular weight of SAPU had effects on the micelle properties. In addition, SAPU exhibited good cytocompatibility estimated by methylthiazole-tetrazolium assay. © 2016 Society of Chemical Industry
研究领域:
材料科学
·
药学
✓ 已验证
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2026
·
IF 5.8
Dan Tu,Ming Chen,Yue Guo,Shuaichao Mao,Yu Shi,Le Yuan,Qifeng Pan,Jianhua Xu,Daniel H.C. Chua
To enhance supercapacitor performance, it is crucial to design electrode materials that are abundant in active sites and incorporate specific functional groups to facilitate rapid ion transport. This study demonstrates the synthesis of star-shaped CoZn-ZIFs using a green method. The derived CoZn-NCs exhibit a wealth of effective functional groups, achieved through the rational tuning of elemental proportions and calcination temperatures. When utilized as a supercapacitor electrode, the Co 1 Zn 1 -NCs/550 electrode attained a specific capacitance of 928 F g⁻¹ at a current density of 0.1 A g⁻¹. Density functional theory (DFT) results further reveal a narrow energy band, suggesting that CoZn-NCs possess good conductivity. A solid-state flexible micro-supercapacitor was constructed using the Co 1 Zn 1 -NCs/550 electrode material. This device exhibited an area capacitance of 637.5 mF cm⁻² accompanied by remarkable electrochemical durability with 97% capacitance retention performance after 5000 cycles at a current density of 1 mA cm⁻². Furthermore, devices connected in series and/or parallel successfully powered light-emitting diodes for several minutes, as demonstrated in a video recording, confirming their potential for practical applications. This work offers promising insights into enhancing energy storage.
✓ 已验证
产品关联
DOI
高影响因子
Biomaterials Science
·
2021
·Vol. 9
·期 7
·2721-2731
·
IF 6.843
Hao Liu,Xu Zhang,Ziyin Zhao,Fangping Yang,Ruizhong Xue,Lichen Yin,Ziyuan Song,Jianjun Cheng,Shifang Luan,Haoyu Tang
Antimicrobial peptides (AMPs) have been considered as a promising new tool to combat the antimicrobial resistance (AMR) crisis. However, the high toxicity and high cost of AMPs hampered their further development. Herein, a series of star poly(L-lysine) (PLL) homo- and copolymers with excellent antimicrobial activity and improved biocompatibility were prepared by the combination of ultra-fast ring opening polymerization (ROP) and side-chain modification. The amine-terminated polyamidoamine dendrimer (Gx-PAMAM) mediated ROP of Nε-tert-butyloxycarbonyl-L-lysine N-carboxyanhydride (Boc-L-Lys-NCA) and γ-benzyl-L-glutamic acid-based N-carboxyanhydride (PBLG-NCA) was able to prepare star PLL homo- and copolymers with 400 residues within 50 min. While the star PLL homopolymers exhibited low minimum inhibitory concentration (MIC = 50–200 μg mL−1) against both Gram-positive and Gram-negative bacteria (i.e., S. aureus and E. coli), they showed high toxicity against various mammalian cell lines. The star PLL copolymers with low contents of hydrophobic and hydroxyl groups showed enhanced antimicrobial activity (MIC = 25–50 μg mL−1) and improved mammalian cell viability. Both SEM and CLSM results indicated the antimicrobial mechanism of membrane disruption.
研究领域:
生物材料学
·
有机化学
·
微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）