ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2025
·
IF 11.3
Yongkang Zhang,Haiyu Qin,Bowen Zu,Zichen Yu,Chunsheng Liu,Jianbo Shi,Bingsheng Zhou
Abnormal development and mortality in early life stages pose significant threats to the growth and continuation of fish populations. Tris(2,4-di-tert-butylphenyl) phosphate (TDtBPP) is a novel organophosphate ester contaminant detected in natural waters. However, the potential effects of maternal exposure to TDtBPP on the early development of offspring embryos in fish remain unknown. Here, 30-day-old zebrafish were exposed to TDtBPP at 0, 50, 500, or 5000 ng/L for 180 days, and the exposed females were spawned with unexposed males. TDtBPP accumulation was detected in offspring embryos, accompanied by an increased malformation rate and mortality. The developmental abnormality of offspring embryos was identified to originate from the gastrula stage. Furthermore, based on transcriptome analysis, the down-regulation of RHO family interacting cell polarization regulator 2 gene (ripor2) was considered as a key toxic event, and this was confirmed in the subsequent knockdown experiment. Moreover, molecular docking studies and forkhead box O1 (foxO1) transcription factor inhibitor (AS1842856) exposure experiments demonstrated that the blockade of foxO1 transcriptional regulation was responsible for the decreased expression of ripor2. The results of this study demonstrated that the occurrence of developmental malformation and mortality in zebrafish offspring embryos following maternal TDtBPP exposure were triggered by the blockade of foxO1 transcriptional regulation and the consequent down-regulation of ripor2.
研究领域:
环境科学
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毒理学
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分子生物学
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DOI
PubMed
高影响因子
MARINE POLLUTION BULLETIN
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2024
·
IF 5.3
Jiani Liu,Yueyong Shang,Fujing Deng,Zhihua Feng,Menghong Hu,Youji Wang
In the marine environment, nanoparticles play a role in adsorbing and catalytically degrading organic pollutants, thereby mitigating their toxic effects on aquatic organisms. This study aimed to investigate the impact of nano titanium dioxide (nTiO 2 ) and tris (2-chloropropyl) phosphate (TCPP) on the hemolymph and digestive function of the thick-shell mussel Mytilus coruscus . Mussels were divided into a control group, a group exposed to TCPP alone, a group exposed to a combination of TCPP and 0.5 mg/L nTiO 2 , and a group exposed to a combination of TCPP and 1 mg/L nTiO 2 . After 14 days of exposure, oxidative stress responses, including superoxide dismutase (SOD) activity and malondialdehyde (MDA) content, immune defense responses, including acid phosphatase (ACP) and alkaline phosphatase (AKP) activities, and gene expression, including HSP70 expression, were measured in the hemolymph and digestive glands of the mussels. Compared to the control group, mussels solely exposed to 100 μg/L TCPP exhibited a significant reduction in SOD activity in the hemolymph. When TCPP was co-exposed with 0.5 mg/L nTiO 2 , there were significant increases in MDA content and AKP activity in both the digestive gland and hemolymph compared to the control group. Upon co-exposure of TCPP with 1 mg/L nTiO 2 , MDA content and AKP activity in the digestive gland significantly decreased, while SOD, ACP, and AKP activity in the hemolymph significantly increased and MDA content significantly decreased, returning to the control group levels. Furthermore, in the combined exposure, HSP70 gene expression significantly decreased as the nTiO 2 concentration increased from 0.5 mg/L to 1 mg/L. In summary, TCPP impacted the hemolymph and digestive function of mussels, whereas a concentration of 1 mg/L nTiO 2 effectively alleviated the toxic effects of TCPP. This study is crucial for assessing the ecological risks of nanoparticles and emerging organic pollutants in marine environments, and provides new insights into the interaction between nTiO 2 and TCPP, as well as the influence of nTiO 2 concentration on mitigating TCPP toxicity.
研究领域:
海洋生物学
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环境科学
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毒理学
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DOI
PubMed
高影响因子
Surfaces and Interfaces
·
2024
·
IF 5.7
Dongxuan He,Gang Wang,Binghan Li,Junrong Huang,Shuming Dou,Wei Gan,Hengzhi You,Qunhui Yuan
Tris(hydroxymethyl)aminomethane (Tris) and its derivatives serve as crucial biological buffers. Presently, Tris is predominantly synthesized by reducing tris(hydroxymethyl)nitromethane using conventional reducing agents such as hydrazine hydrate and metal powders. However, hydrazine hydrate poses a significant threat to aquatic life, while the use of reducing metal powders generates substantial solid waste, thereby exerting considerable environmental pressure in terms of green and sustainable chemistry. The utilization of non-homogeneous catalysts for hydrogenation reduction offers a viable solution to mitigate these issues. Yet, the exploration of non-homogeneous catalysts remains incomplete and lacks comprehensive research. In this study, a highly active Pd/C catalyst for the hydrogenation reduction of tris(hydroxymethyl)nitromethane was fabricated, through an ultrarapid high-temperature thermal shock (HTS) synthesis. The ultrafine Pd particles (∼5.5 nm) are uniformly distributed on the carbon substrate, rendering the catalyst high activity and stability. Additionally, we successfully combine this heterogeneous catalyst with continuous flow technology and achieve a continuous and stable production of Tris for more than 8 h, with a satisfying yield of ∼96%. This report may shed light on the efficient fabrication of more ultrafine catalysts for hydrogenation reductions with high noble-metal utilization.
研究领域:
化学工程
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环境科学
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材料科学
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产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2026
·
IF 10.6
Jukun Xiong,Suyun Chen,Zixuan Wei-Xiong,Chang Yuan,Meicheng Wen,Wanjun Wang,Qinhao Lin,Yingxin Yu
In this study, carbon isotope analysis was employed to investigate hydrolysis and natural pyrite-activated persulfate (NP/PDS) degradation of TCPP. EPR and radical quenching experiments revealed that • OH and SO 4 • ⁻ were the dominant reactive oxygen species. The XPS, XRD, and FTIR results indicated Fe(Ⅱ) served as the primary active site, generating • OH and SO 4 • ⁻. For acidic and neutral hydrolysis, the apparent kinetic isotope effects ( 13 C-AKIE = 1.031 ± 0.004 and 1.030 ± 0.004, respectively) were consistent with the intrinsic KIE associated with C–O bond cleavage (1.00–1.03), suggesting that C–O bond cleavage was the initial rate-limiting step. In contrast, negligible carbon isotope fractionation during alkaline hydrolysis indicated that P–O bond cleavage was the initial rate-limiting step. For degradation in the NP/PDS, the observed 13 C-AKIEs were 1.009 ± 0.001, 1.004 ± 0.000, and 1.005 ± 0.001, respectively. These values were inconsistent with intrinsic KIEs expected for C-H (1.01–1.03) and C-Cl (1.02–1.03) bond cleavage but corresponded to the lower end of the intrinsic KIEs range for C–O bond cleavage, indicating that P–O bond cleavage was the initial rate-limiting step. Overall, this study demonstrates isotope analysis is a powerful tool for identifying the geochemical mechanisms of OPFRs in contaminated fields.
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高影响因子
JOURNAL OF MOLECULAR STRUCTURE
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2020
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IF 2.463
Meiyu Xu,Guangming Liang,Shuang Wang,Xueli Ma,Guangyuan Liang,Qingling Ni
The semi-rigid polycarboxylic acid, 4′,4′,4′-[(trimethylamino)]-tris[(1,1′-biphenyl)-2-car- boxylic acid] (H 3 TMCA), is first synthesized and used to self-assembly three cadmium coordination polymers , formulated as {[Cd(HTMCA)]•(H 2 O)•(DMA)} n (1), {[Cd(HTMCA)(H 2 O)]·(H 2 O) 5 } n (2), {[Cd(TMCA)] - (CH 3 CH 3 NH 2 ) + •H 2 O} n (3) by the reaction of Cd(NO 3 ) 2 ·4H 2 O under solvothermal conditions. The coordination polymers have been characterized by elemental analysis , IR spectroscopy , thermogravimetric analysis and single-crystal X-ray diffraction. Complex 1 is a 2D framework with a point symbol of {6˄3}. Complex 2 exhibit a 3D topology net with point symbol of {10˄3}. Complex 3 display a (3,6)-connected 3D topology net with point symbol of {4.6 2 } 2 {4 2 .6 10 .8 3 }. The structural comparison of complexes 1–3 shows that the final frameworks can be adjusted by changes in the reaction of temperature and solvents. Moreover, the solid-state photoluminescence properties of 1 – 3 have also been investigated.
研究领域:
化学
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材料科学
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DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2021
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IF 4.539
Li Zhang,Shaobin Li,Kevin P. O’Halloran,Zhuanfang Zhang,Huiyuan Ma,Xinming Wang,Lichao Tan,Haijun Pang
In this work, a highly sensitive non-enzymatic electrochemical sensor based on an inorganic-organic nanocomposite film consisting of H 7 P 2 Mo 17 V 1 O 62 (P 2 Mo 17 V), Ru(bpy) 3 Cl 2 ·6H 2 O (Ru(bpy) 3 ) and chitosan-palladium (Cs-Pd) was constructed for the determination of ascorbic acid (AA). The non-enzymatic sensor has advantages such as simple preparation and operation, good reproducibility and superior sensitivity, which overcomes the drawbacks of enzyme-based sensors such as restricted immobilization and easy inactivation due to the combination of three active components in the new film presented here. The sensor displays excellent sensing performance for the detection of ascorbic acid with a fast response time (< 2 s), a wide linear range of 0.125–118 μM and a low detection limit of 0.1 μM (S/N = 3). In addition, the sensor was successfully employed to detect AA in juice.
研究领域:
分析化学
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材料科学
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生物医学工程
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DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2022
·Vol. 33
·期 6
·2210036
·
IF 19.924
Wen Li,Wen Liu,Jin Zhang,Haining Wang,Shanfu Lu,Yan Xiang
Porous proton exchange membranes (PEMs) with abundant porous structures show enhanced phosphoric acid (PA) doping levels and proton transport capability. However, the high PA loss rate and serious hydrogen cross-over lead to poor membrane stability. Enhancing the stability of PA-doped porous PEMs is therefore crucial for obtaining high-performance proton exchange membrane fuel cells. Herein, a porous polybenzimidazole membrane with dense double skin layers is reported using amino tris (methylene phosphonic acid) (ATMP) constructed. This membrane effectively alleviates hydrogen permeation and PA loss in a water/anhydrous environment and exhibits enhanced stability. Surprisingly, as an organic proton conductor, ATMP has strong hydrogen bonding with PA, leading to the formation of more continuous proton transport channels. Due to the dense double skin layers protection and the synergistic mass transfer of ATMP and PA, the porous membrane shows excellent proton conductivity (0.112 S cm −1 ) and a H 2 -O 2 fuel cell peak power density of 0.98 W cm −2 at 160 °C. Moreover, it presents excellent fuel cell stability, with a voltage decay rate of only 5.46 µV h −1 . In addition, the porous membrane surpasses the traditional working temperature range, operating in the range of 80–220 °C. This study provides new insight into developing high-performance porous PEMs.
研究领域:
材料科学
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燃料电池技术
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Mengyao Li,Haifei Wan,Jingyong Xiong,Linyu Wang,Li Yang,Li Wang,Yonghai Song
Luminescent covalent organic frameworks (LCOFs) is a promising luminescent material with huge potential for various applications because it can integrate various chromophores into its porous ordered structure. A facile and effective approach to edit LCOFs emission is very necessary but remains a challenge. Herein, a rigidity-flexibility combination strategy to edit the luminescence properties of LCOFs was proposed by using a flexible fluorescent 1,3,5-tris(phenylacetylene) benzene with propeller-like conformation as center skeleton and linkers with different rigidity and conjugation degree. Since the conjugated degree of LCOFs’ frameworks depended on conformation of propeller-like 1,3,5-tris(phenylacetylene)benzene skeleton, the emission wavelengths of 1,3,5-tris (phenylacetylene)benzene-based LCOFs could be edited by linkers to tune conjugated degree of the frameworks. These 1,3,5-tris(phenylacetylene)benzene-based LCOFs emitted blue, green, yellow, orange and red light depending on the conjugation degree caused by the effect of the linkers of melem, terephthalic dihydrazide, hydrazine hydrate and p-phenylenediamine on the conformation of central skeleton. Binary or ternary mixed 1,3,5-tris(phenylacetylene)benzene-based LCOFs were used for white emission, white light-emitting diodes and information encryption/decryption. The work provides a simple yet efficient method to systematically edit the emission behaviors of LCOFs by linker engineering.
研究领域:
材料科学
·
光学
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DOI
高影响因子
Journal of Materials Chemistry B
·
2018
·Vol. 6
·期 37
·6008-6015
·
IF 4.776
Fengyi Wang,Xuan Hu,Jing Hu,Qianqian Peng,Baozhan Zheng,Juan Du,Dan Xiao
In this study, bimetallic lanthanide coordination polymer nanoparticles (Tb-GMP-Eu CPNs) were developed for sensing alkaline phosphatase (ALP) by utilizing guanine monophosphate (GMP) as the bridge ligand to self-assemble with Tb3+ and Eu3+ in Tris–HCl buffer solution. In this polymer framework, an efficient energy transfer from Tb3+ to Eu3+ occurred because the emission energy of Tb3+ matched well with the absorption energy of Eu3+. As a result, the synthesized Tb-GMP-Eu CPNs exhibited the characteristic red emission of Eu3+ when excited at 290 nm. When ALP was introduced into the Tb-GMP-Eu CPNs system, it would destruct the combination between Tb and GMP by a dephosphorylation process, resulting in interruption of energy transfer from Tb3+ to Eu3+ and therefore the fluorescence quenching of Eu3+. Based on these facts, a fluorescence assay based on bimetallic lanthanide coordination polymer nanoparticles for ALP detection was developed. Such a Tb-GMP-Eu CPNs sensor exhibited sensitive response to ALP with a detection limit down to 0.004 U L−1. Moreover, the successful application of ALP inhibitor evaluation and determination of ALP in serum samples have been demonstrated. Therefore, the proposed method has great potential application for ALP detection in biological and clinical diagnosis.
研究领域:
分析化学
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生物化学
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纳米技术
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生物医学工程
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临床诊断
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产品关联
DOI
PubMed
高影响因子
Nanomaterials
·
2024
·Vol. 14
·期 5
·390
·
IF 4.4
Ruliang Yu,Yujiao Zhao,Jiyang Liu
Convenient and highly sensitive detection of oxalate ions in body fluids is of crucial significance for disease prevention, diagnosis, and monitoring of treatment effectiveness. Establishing a simple solid-state electrochemiluminescence (ECL) sensing system for highly sensitive detection of oxalate ions is highly desirable. In this work, a solid ECL sensor was fabricated by immobilizing the commonly used emitter ruthenium(II)tris(bipyridine) (Ru(bpy)32+) on a double-layered bipolar silica nanochannel array film (bp-SNA)-modified electrode, enabling sensitive detection of oxalate ions in serum or urine samples. Cost-effective and readily available indium tin oxide (ITO) was used as the supporting electrode. Convenient fabrication of multiple negatively charged SNA (n-SNA)-modified ITO electrodes was achieved through the one-step Stöber solution growth method. Subsequently, a positive outer layer film (p-SNA) was rapidly prepared using an electrochemical-assisted self-assembly method. The double-layered bipolar silica nanochannel array film achieved stable immobilization of Ru(bpy)32+on the electrode surface, facilitated by the electrostatic adsorption of Ru(bpy)32+by n-SNA and the electrostatic repulsion by p-SNA. Utilizing oxalate ions as a co-reactant for Ru(bpy)32+, combined with the electrostatic enrichment of oxalate ions by p-SNA, the constructed sensor enabled highly sensitive detection of oxalate ions ranging from 1 nM to 25 μM and from 25 μM to 1 mM, with a detection limit (LOD) of 0.8 nM. The fabricated ECL sensor exhibited high selectivity and good stability, making it suitable for ECL detection of oxalate ions in serum and urine samples.
研究领域:
分析化学
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医学诊断
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生物传感
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产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
·
2026
·
IF 2.8
Chen Cijia,Gao Ning,Ma Jiayu,Yang Lanpeng,Zhu Lin,Feng Jianfeng
Micro(nano)plastics (MNPs) are both pollutants and carriers of other toxic pollutants, which produce complex combined effects with coexposed pollutants. Tris (1,3-dichloro-2-propyl) phosphate (TDCIPP), a widely used organophosphate ester plasticizer and flame retardant in plastics, was selected to examine how MPs and NPs modulate its bioaccumulation and toxicity in zebrafish embryos. The results indicated that MPs did not significantly affect the bioaccumulation or toxicity of TDCIPP in embryos. In contrast, NPs increased the accumulation of TDCIPP in embryos, thereby enhancing adverse effects on hatching, development, and survival. Toxicokinetic (TK) and toxicodynamic (TD) models were applied to validate the influence of MPs and NPs on the bioaccumulation and toxicity of coexisting pollutants. The TK-TD modeling revealed that MPs had no significant effect on the bioconcentration factor (BCF) or internal threshold concentration (CIT) of TDCIPP, whereas NPs significantly increased BCF and decreased CIT. Moreover, the ratio CIT/BCF was found to explain the differential toxicity effects of TDCIPP in the presence of MPs and NPs. This study quantified the disparate effects of MPs and NPs at environmental concentrations on the bioaccumulation and toxicity of TDCIPP from the TK-TD perspective, contributing to a better understanding of the toxicity mechanism of the mixture.
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DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Lucheng Li,Meiling Liu,Peng Yang,Wenfeng Yuan,Jun Chen
Broadening the charging and discharging voltage window of high nickel cathode material NCM811 is the most expected method to improve the high specific energy density of batteries currently, yet the cathode-electrolyte interface (CEI) formed by the oxidized and decomposed products of carbonate-based electrolyte under high voltage are always so unsatisfied. Therefore, a voltage-stabilizer, TPFPB (Tris(pentafluoro)phenylborane), added into baseline electrolyte (1 M LiPF 6 in EC:EMC:DMC=1:1:1 vol%) to promote the electrochemical performance of the battery at 4.5 V. The results interpret that the TPFPB-contained NCM811-Li half-cells exhibit high specific capacity (167.10 mAh/g), excellent capacity retention rate (CRR) (75.37 %), and high rate performance (173.3 mAh/g at 5C) during 4.5 V. Meanwhile, through the analysis of the physical characterization techniques. the B- and F-rich interfacial layer, named as CEI film, existing at the interface between the cathode and the electrolyte, produced under 4.5 V, is superior, resulting in impeding the structural collapse of the cathode material and the continued dissolution of transition metal ions (TM n + ) from the cathode material, as well as, ameliorate the electrochemical polarization of the battery, ultimately, it can stabilize the electrochemical performance of the battery under high voltage. Therein, the present work elucidate a new and substantial approach to enhance the high-voltage performances of rich-Ni cathode materials.
研究领域:
材料科学
·
电化学
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产品关联
DOI
PubMed
高影响因子
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