MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Raj Kumar Parajuli,Jin Liu,Shree Krishna Tamang,Govinda Gurung,Kumar Neupane,Yao Wang,Christopher D. Snow,Matt J. Kipper,Laurence A. Belfiore,Jianguo Tang
Patient urine may provide relatively convenient access to biomarkers, but it is challenging to directly and visibly sense drugs via fluorescence quenching or enhancement. This study reports the synthesis of water-soluble and fluorescence-stable terbium-induced nanoaggregates (TIPAs) of polystyrene-poly(acrylic acid) (PS- b -PAA), containing a novel [Tb( acac )Cl 2 ( phen )Cyclen] complex, to sense doxorubicin ( dox ) in urine. The TIPAs demonstrated remarkable water stability, maintaining high fluorescence intensity in aqueous environments, with a fluorescence lifetime of 55.5 ms and a quantum yield (QY) of 4.60 %, making them ideal for smart sensing applications. The novel aggregate exhibits an orthorhombic structure, with its photophysical properties elucidated through simulated modeling. Fluorescence quenching studies indicate dynamic interactions between TIPAs and dox in urine, achieving a limit of detection (LOD) of 13.77 μM, highlighting the method's sensitivity for real-time dox monitoring. The emission of TIPAs in the visible range (450–600 nm) overlaps with the absorption spectrum of dox , enabling efficient energy transfer and fluorescence quenching. These findings highlight the potential of TIPAs as stable, fluorescence-based sensors for drug monitoring, with promising applications in bioimaging and diagnostics within cancer therapy.
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高影响因子
ACS Applied Materials & Interfaces
·
2015
·
IF 6.723
Yong’an Tang,Jun Hu,Ahmed H. Elmenoufy,Xiangliang Yang
Photodynamic therapy (PDT) for deep-seated tumor is largely impeded by the limited penetration depth of excitation light in tissue. X-ray is considered as an ideal energy source to activate photosensitizers (PSs) located deep within the body with the assistance of scintillating nanoparticles (ScNPs). However, the efficacy under this concept is not satisfying due to the low scintillating luminescence and weak energy transfer from ScNPs to PSs. Here, mesoporous LaF3:Tb ScNPs were successfully synthesized by a facile hydrothermal process to act as PS carriers and X-ray energy transducers, owing to their good ionizing radiation stopping power and high luminescence efficiency. The formation mechanism of porous structure was elucidated in detail with classical crystallization theory. After a systematic investigation, LaF3:Tb ScNPs with optimized scintillating luminescence were obtained for loading Rose Bengal (RB) to establish an efficient FRET system, owing to their excellent spectral match. The FRET efficiency between ScNPs and RB was calculated to be as high as 85%. Under irradiation, enhanced 1O2 generation induced by LaF3:Tb-RB nanocomposites via FRET process was detected. This LaF3:Tb-RB FRET system shows great potential to be applied in X-ray stimulated PDT for deep-seated tumors in the future.
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高影响因子
OPTICAL MATERIALS
·
2016
·
IF 2.183
Chen Yuan,Hongde Xie,Haijun Cai,Cuili Chen,Peiqing Cai,Hyo Jin Seo
A green-emitting Tb(III) complex based on siloxane-modified pressure sensitive adhesives (SPSA-Tb(III)) was successfully synthesized by emulsion polymerization . Siloxane-modified pressure sensitive adhesives (SPSA) were used as host materials. The structural coordination, photoluminescence excitation (PLE) and luminescence (PL) spectra, and thermal characterization of this luminescent polymer were investigated. The result from the FT-IR spectra reveals that SPSA have successfully coordinated with the Tb(III) ions. The luminescent analysis indicates that SPSA-Tb(III) displays Tb(III) typical emission peaks at 489, 545, 583, and 622 nm under the excitation of 369 nm. When monitored at 545 nm, strong and sharp excitation bands appear from 300 to 500 nm. And SPSA-Tb(III) has short lifetime (0.25 ms). Meanwhile, SPSA-Tb(III) exhibits high thermal stability (T d = 402 °C) owing to the high bond dissociation energy of Si O bonds. All the results suggest that it is expected to be used as a superior green-emitting material under high temperature.
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CRYSTENGCOMM
·
2026
·
IF 2.4
Jicong Lin,Yushu Dai,Jintao Xu,Mengjie Xu,Xieming Xu,Hao Lu,Shaofan Wu,Shuaihua Wang
LiLuF4 microcrystalline scintillation materials possess several advantages, including high chemical stability, simplified fabrication processes, and tunable emission wavelengths. These materials demonstrate significant potential in fields such as X-ray imaging, biodiagnostics, photodynamic therapy, advanced anti-counterfeiting, and thermally activated delayed imaging. However, the relatively weak radioluminescence intensity of single rare-earth-doped LiLuF4 crystals has constrained their practical applications. In this work, Ni2+ co-doped LiLuF4:Tb microcrystalline scintillators are synthesized via a hydrothermal method. The incorporation of heterovalent Ni2+ ions effectively enhanced both the radioluminescence and thermoluminescence intensities of LiLuF4 microcrystals. After doping with 3 mol% Ni2+ ions, the radioluminescence intensity increased by 125.34%. The X-ray detection limit of LiLuF4:Tb,Ni reaches 3.7966 nGy s−1, which is considerably lower than the medical imaging requirement of 5.5 μGy s−1. Furthermore, a large-area flexible composite scintillation film of dimensions 80 mm × 145 mm was prepared to achieve high-spatial-resolution X-ray imaging of 25 LP mm−1@20% MTF, indicating that heterovalent-doped fluoride scintillators possess exceptional application potential.
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INORGANIC CHEMISTRY
·
2024
·
IF 4.3
Huan Dai,Zichen Xu,Ke Yang,Jianchao Zhou,Jing Wang,Ya Zhang,Yudong Shen,Xiaolan Liu,Yue Jiang,Wei Xu
The utilization of metal–organic frameworks (MOFs) as fluorescent sensors for the detection of environmental and chemical reagent pollutants as well as heterogeneous catalysis for CO2 conversion represents a crucial avenue of research with significant implications for the protection of human health. In this work, a Tb(III)-based three-dimensional metal–organic framework, [Tb(L)·4DMF]n (Tb-MOF) (H3L = 5′-(4-carboxy-3-hydroxyphenyl)-3,3″-dihydroxy-[1,1′:3′,1″-terphenyl]-4,4″-dicarboxylic acid), has been structurally conformed by single-crystal X-ray crystallography. It possesses a 1D rhombus channel along the [010] direction, featuring a pore size of 6.02 × 9.13 Å. Tb-MOF was proved to be a multifunctional material for a fluorescent sensor and CO2 cycloaddition heterogeneous catalyst material. Fluorescence sensing studies revealed that Tb-MOF demonstrates high sensitivity, selectivity, and favorable regeneration properties, making it an effective chemosensor for detecting the metamitron (MMT) pesticide and trace water in organic solvents. The mechanism of fluorescence quenching by MMT and water was elucidated by a combination of XRD, UV–vis absorption spectra, IR spectra, theoretical calculations, and fluorescence lifetimes. The material was also utilized for the sensing of MMT and water in paper strips. Additionally, the open Tb3+ site as Lewis acidic centers makes Tb-MOF achieve efficiently catalytic conversion for CO2 and epoxides to cyclic carbonates. Moreover, a possible catalytic mechanism for the conversion of carbon dioxide to cyclic carbonates was proposed by in situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) experiments. It also exhibited recyclability for up to five cycles without noticing an appreciable loss in sensing or catalytic efficiency.
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PubMed
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2026
·
IF 4.1
Zhao Ziyu,Shan Xueling,Wu Yuqi,Jiang Ding,Wang Wenchang,Du Xiaojiao,Chen Zhidong
The residue of chloramphenicol (CAP) in animal-derived foods and the environment poses a serious threat to human health, highlighting the urgent need for sensitive, selective, and rapid detection methods. In this study, a novel electrochemiluminescence resonance energy transfer (ECL-RET)-based sensing platform was developed for the ultrasensitive detection of CAP, employing a Tb-PTC/Ag MOF composite as the energy donor and hollow ZIF-8@polydopamine (ZIF-8@PDA) as the energy acceptor. Coordination of Tb 3+ with PTCA ligands within the MOF framework effectively suppressed aggregation-induced quenching, while the incorporation of Ag MOF further enhanced and stabilized the ECL intensity through synergistic effects. Efficient ECL-RET was achieved owing to the spectral overlap between the UV-vis absorption of the acceptor and the ECL emission of the donor, with a high energy transfer efficiency of 75.1%, significantly improving the sensitivity of the sensor. The proposed platform exhibited a wide linear range from 10 −5 to 10 −15 mol L −1 for CAP detection, with an exceptionally low detection limit of 1.57 × 10 −15 mol L −1 . By integrating the structural advantages of MOFs with the high sensitivity of the ECL-RET strategy, this work establishes a robust and promising platform for trace-level CAP monitoring in environmental and food samples. Graphical abstract
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PubMed
高影响因子
CRYSTENGCOMM
·
2022
·Vol. 24
·期 14
·2542-2550
·
IF 3.756
Ming-Yang Cao,Chun-Li Hu,Peng-Fei Chen,Qian Wang,Bing-Xuan Li,Yuan Lin,Jiang-Gao Mao
Three nonlinear optical materials Cd4REO(BO3)3 (RE = Sm, Eu, Tb) have been synthesized through high-temperature solid-state reactions. In their crystal structures, Cd(1)O8 and Cd(2)O6 polyhedra are interconnected via sharing edges and corners into a 3D anion framework with two types of tunnels based on 4- and 7-membered rings; the BO3 groups are grafted into the above-mentioned types, creating new tunnels based on Cd4B3 seven-membered rings, which are filled by RE3+ cations. Powder SHG measurements revealed that the Cd4REO(BO3)3 (RE = Sm, Eu, Tb) samples display SHG signals that are approximately 1.2, 5.6 and 1.5 times that of the KDP sample. In addition, Cd4EuO(BO3)3 and Cd4TbO(BO3)3 emit red and green light, respectively. The lifetime of the Eu(5D0) state for λex,em = 464, 610 nm in Cd4EuO(BO3)3 is measured to be about 1.43 ms whereas the lifetime of the Tb(5D4) state for λex,em = 376, 543 nm in Cd4TbO(BO3)3 is measured to be about 1.01 ms.
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OPTICAL MATERIALS
·
2021
·
IF 3.08
Panpan Du,Qi Zhu,Xiaodong Li,Xudong Sun,Byung-Nam Kim,Ji-Guang Li
A series of garnet-type Li 6 CaLa 2(1- x ) Nb 2 O 12 : x RE phosphors (LCLN: x RE, RE = Pr, Sm, Tb and Dy) were prepared via sol-gel processing and subsequent calcination for the first time, with the course of phase evolution and the characteristics of the LCLN host and RE 3+ luminescence being investigated in detail. It was found that ∼900–1000 °C is a suitable temperature for precursor calcination to produce the garnet phase and LCLN has a relatively low phonon energy (∼725 cm −1 ) and a relatively wide bandgap (∼4.53 eV) for luminescence. The LCLN:0.012Pr, LCLN:0.04Sm, LCLN:0.06 Tb and LCLN:0.06Dy typical phosphors were analyzed to have dominant excitation/emission bands at ∼278/489, 265/614, 268/549 and 264/581 nm, emission colors of white, orange, green and yellowish white, and fluorescence lifetimes of ∼0.43, 0.74, 0.90 and 0.44 ms, respectively. Temperature-dependent photoluminescence found that the four phosphors maintained ∼28, 37, 45 and 56% of their room-temperature intensities at 423 K, with activation energies for thermal quenching of ∼0.37, 0.29, 0.34 and 0.25 eV, respectively. The results demonstrated that the Li-stuffed LCLN garnet could be a suitable host for UV excitable multicolor phosphors.
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INORGANIC CHEMISTRY
·
2022
·
IF 5.436
Min Chen,Zhengli Liang,Xiaoxiao Wang,Jiehua Li,Xingguo Chen,Xingxing Jiang,Zheshuai Lin,Zhen Ma,Hongming Liu
A series of lanthanide-containing water-resistant nitrates, namely RE(OH)2NO3 (RE = Tb(1), Dy(2), Ho(3), and Er(4)), was obtained through the hydrothermal process. As possible nonlinear optical materials, they feature a layered isomorph composed of an [REO3(OH)6] polyhedron and an [NO3] triangle, and the synergistic arrangement of the [REO3(OH)6] and [NO3] groups in their structures leads to their obvious second-order nonlinear optical effect. Nevertheless, the unique optical absorption caused by the electronic transitions on 4f–4f orbitals of lanthanides results in their second harmonic generation responses of different strengths, with 1 exhibiting 5.07 times that of KDP, but 2–4 showing less than half of KDP. In addition, 1 possesses an outstanding water-resistant capacity and a transparent cut-off edge around 300 nm, foreshadowing its potential value as a nonlinear optical crystal. Moreover, 1 is found to emit characteristic green fluorescence due to the typical 5D4 → 7F5 transitions of the excited Tb3+ ions
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高影响因子
MICROCHIMICA ACTA
·
2018
·Vol. 185
·期 7
·1-8
·
IF 5.705
Sun Chongmei,Yuan Fangzheng,Li Huihui,Wu Xia
A nanoprobe was developed for the fluorometric determination of the neurotransmitter dopamine (DA). It is based on the synergistic enhancement action of citrate and gold nanoparticles (AuNPs) on the luminescence of Tb(III). AuNPs serve as substrates of surface enhanced fluorescence (SEF). Citrate, in turn, acts as a spacer for the SEF effect, a co-ligand of Tb(III) complex, and a recognizing component for DA. The synergistic action of citrate and AuNPs significantly increases the intrinsic green fluorescence of Tb(III) (best measured at excitation/emission peaks of 300/547 nm). Under the optimum conditions, the fluorescence intensity increases linearly in the 3.0 to 200 nM DA concentration ranging (with an R 2 value of 0.9959), and the limit of detection (at S/N = 3 ) is 0.84 nM. The nanoprobe shows good selectivity for DA among other interfering neurotransmitters, some amino acids and ions. The method was applied to the detection of DA in human serum samples where it gave recoveries ranging from 100.5 to 102.9%.
Schematic of a Tb(III) composite fluorescent nanoprobe for the sensitive determination of dopamine (DA). Citrate and gold nanoparticles (AuNPs) synergistically enhance the fluorescence of Tb(III)-DA.
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高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Yuxin He,Hecun Zou,Xinhui Jiang,Yanrui Wei,Siqiao Li,Tong Wu,Zhengwei Zhang
Foodborne residue of carbendazim (CBZ) poses a major threat to human health. Here, we rationally designed a smartphone-assisted fluorescent sensor based on bimetallic-organic framework (Eu/Tb-MOF) for ultrasensitive and visual monitoring of CBZ. The Eu/Tb-MOF nanorods fabricated using Eu 3+ /Tb 3+ as metal nodes and homobenzoic tricarboxylic acid (H 3 BTC) as organic ligand exhibit superior optical properties. After adding CBZ, the strong orange fluorescence of Eu/Tb-MOF nanorods was suppressed by the inner filter effect (IFE). The linear ranges of the fluorescent sensor were 0.01–15 and 15–80 µg/mL, with a detection limit as low as 7.09 ng/mL. The analyses of CBZ residue in tomato and orange samples showed satisfactory recoveries of 99.32 %–101.97 % and low relative standard deviations of 0.87 %–3.44 %., verifying the practicality of the probe for CBZ. Notably, a simple and portable smartphone-assisted sensing platform based on the Eu/Tb-MOF nanorods was successfully constructed for quick, visual, and real-time monitoring of CBZ residue. This work provides an efficient onsite analytical method for assessment and warning-early of CBZ to safeguard food quality
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Z.H. Xu,C. Wang,X.Z. Xiong,W.B. Dai
Borate-based phosphors, as a critical class of luminescent materials, have garnered significant attention due to their stable crystal structures, wide bandgaps, excellent thermal stability, and robust spectral tunability, making them essential components in white light-emitting diodes ( w LEDs) technologies. In this work, a high-symmetry Ba 3 Y 2 B 6 O 15 (BYB) phosphor co-doped with Bi 3+ , Tb 3+ , Eu 3+ , and Lu 3+ was synthesized via a multi-step sol-gel method. Different photoluminescence (PL) behaviors of Bi 3+ , Tb 3+ and Eu 3+ in BYB were systematically revealed. By modulating the PL spectrum via energy transfer (ET) from Bi → Tb → Eu, ‘cool’ white-light emission was achieved. A strategy of replacing Y 3+ with Lu 3+ was adopted to adjust the crystal field splitting and symmetry. This modification broadens the blue light coverage range in Bi 3+ PL, increases the hypersensitive transition of Eu 3+ ( 5 D 0 → 7 F 2 ), increase the intensity of red emission. They achieved their optimal balance ultimately. The improved structural compactness and rigidity reduced electron-phonon coupling effects, endowing the phosphor with superior chemical/thermal stability. Finally, a high-performance phosphor-converted w LED (pc- w LED) device with chromaticity coordinates of (0.361, 0.358), a luminous efficacy (LE) of 95.2 lm/W, was fabricated by integrating the optimized BYB: Bi/Tb/Eu/Lu phosphor with a UV LED chip using remote ‘cap’ packaging, demonstrating exceptional performance.
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