OPTICS AND LASER TECHNOLOGY
·
2026
·
IF 5.2
Wei Gao,Jiaxi Li,Junlin Qi,Qingyan Han,Chengyun Zhang,Xuewen Yan,Jun Dong
Balancing red-emission intensity and the red-to-green (R/G) emission ratio remains an important challenge in Er 3+ -based upconversion nanoparticles. Herein, a multilayer core–shell architecture was developed to achieve differential regulation of red-emission intensity and the red-to-green (R/G) emission ratio in Er 3+ -based upconversion nanoparticles. After screening NaYbF 4 : x %Er 3+ @NaYF 4 core–shell nanoparticles, the sample containing 2% Er 3+ exhibited a favorable balance between overall emission intensity and the R/G ratio and was therefore selected as the precursor for constructing NaYbF 4 :2%Er 3+ @NaYF 4 @NaErF 4 :y%M 3+ @NaYF 4 (M = Yb or Tm) multilayer nanoparticles. In this architecture, the Yb-rich core, intermediate NaYF 4 layer, compositionally tunable Er-rich shell, and outer NaYF 4 shell were designed to provide spatially differentiated excitation harvesting, interfacial modulation, spectral regulation, and surface passivation, respectively. Under identical 980 nm excitation and collection conditions, incorporation of 15%Yb 3+ into the Er-rich shell increased the integrated red-emission intensity to 2.40 times that of the undoped multilayer counterpart, whereas incorporation of 0.5%Tm 3+ produced the highest R/G ratio of 17.1 while retaining comparatively strong emission. Power-dependent and time-resolved luminescence measurements, together with the proposed energy-transfer model, indicate that Yb 3+ incorporation is predominantly associated with enhanced local excitation sensitization and energy utilization within the Er-rich region, whereas trace Tm 3+ incorporation is more closely associated with excited-state population redistribution toward the red-emitting pathway. These results demonstrate that red-emission intensity and the R/G ratio can be differentially regulated within the same multilayer platform through Yb 3+ or Tm 3+ incorporation into the Er-rich shell. This work provides a spatially organized and compositionally tunable strategy for tailoring red upconversion emission in Er 3+ -based multilayer nanoparticles.
✓ 已验证
产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2019
·
IF 6.97
Huijie Zhang,Yuqing Xiao,Fei Qi,Pei Liu,Yuan Wang,Fangjie Li,Changlei Wang,Guojia Fang,Xingzhong Zhao
Hexagonal NaYF4:Yb3+,Tm3+@SiO2 upconversion nanoprism-mixed SiO2 passivation layers are introduced into hole-transport-layer free carbon-based perovskite solar cells to improve the power conversion efficiency. This layer on the top of the TiO2 scaffold has multiple functions: (i) upconversion units could transform near-infrared photons to visible region and thus extend the absorption range; (ii) nanoprisms act as light-scattering centers to prolong light-transmission distance and enhance light harvesting; (iii) SiO2 capping layer could suppress charge recombination at the interface of perovskite/TiO2 through passivation effect. The champion efficiency of our carbon-based device with an optimal amount of upconversion nanoprisms is 14.47%, which is 16.1% higher than that of the reference (12.46%). In addition, our unencapsulated solar cells exhibit good stability against moisture and thermal stressing in ambient condition. We also demonstrated another application of our device as a self-powered photodetector with NIR-sensitive features.
研究领域:
材料科学
·
光电子学
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry C
·
2024
·Vol. 12
·期 37
·15070-15081
·
IF 5.7
He Lin,Shuangqiang Fang,Tianchun Lang,Jiali Yu,Haoliang Cheng,Jiaqi Ou,Zhijie Ye,Renjie Xu,Xiulan Shui,Haolin Qu,Le Wang
Near-infrared (NIR) luminescent materials exhibit unique photophysical properties that make them crucial components in photobiological, photonic and optoelectronic applications. Nonetheless, almost all rare earth ions are difficult to be efficiently excited by blue light for NIR emission, mainly due to the inherent electron shielding effect of 5s25p6 orbitals. Here, an amazing enhancement of the Tm3+ 3H4 → 3H6 transition (800 nm) was achieved in the SrGa12O19 host upon 450 nm excitation. Compared with the Tm3+ single-doped sample, the internal quantum efficiency (IQE) in the 700–900 nm range was significantly improved from less than 1% to 74%, and the external quantum efficiency (EQE) was enhanced from nearly 0 to 33%, benefitting from the synergistic effect of Cr3+ contribution and electron shielding effect breaker of In3+. XRD structure refinement, time-resolved fluorescence spectroscopy and electron paramagnetic resonance were used to determine the effect of Cr3+ and In3+ doping. Furthermore, the universality of this strategy has also been verified with other rare earth ions (Ho3+, Nd3+, and Yb3+). Finally, a NIR phosphor-converted LED (pc-LED) is fabricated, exhibiting a satisfactory output power of 141 mW@500 mA and demonstrating the potential for photosynthetic bacteria culture, venous imaging and non-destructive testing. This work opens a window for blue light-pumped NIR emission of rare earth ions.
研究领域:
材料科学
·
光学
·
生物光子学
·
光生物学
✓ 已验证
DOI
高影响因子
BIOMATERIALS
·
2011
·
IF 7.883
Ao Xia,Yuan Gao,Jing Zhou,Chunyan Li,Tianshe Yang,Dongmei Wu,Limin Wu,Fuyou Li
New core–shell structured NaYF 4 :Yb 3+ ,Tm 3+ @Fe x O y nanocrystals , with 20 nm Yb 3+ ,Tm 3+ -co-doped NaYF 4 nanocrystals as a core and 5 nm Fe x O y nanocrystals as a shell, have been synthesized and characterized by TEM and XRD analysis . These core–shell nanocrystals exhibit excellent near-infrared upconversion luminescence (UCL) emission at 800 nm under excitation by a continuous-wave 980 nm laser and superparamagnetic properties with a saturation magnetization (Ms) of ∼12 emu/g. Water-soluble nanocrystals were obtained by surface ligand exchange of oleic acid-coated precursor nanocrystals, and their internalization within living cells has been investigated by laser scanning UCL microscopy. Furthermore, the obtained core–shell nanocrystals have been applied in dual-modality T 2 -enhanced magnetic resonance (MR) and UCL imaging in vivo of the lymphatic system. Moreover, the toxicity of NaYF 4 :Yb 3+ ,Tm 3+ @Fe x O y nanocrystals has also been evaluated by MTT assay, IC50 values, and histological analysis of lymphatic node sections.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TOXICOLOGY
·
2025
·
IF 4.6
Mei-Ling Le,Jia-Yu Xue,Li-Hai Wu,Xin-Yuan Zhao,Jing Ding,Yang-Yang Yuan,Yi-Qi Wan,Da-Lei Zhang
Hexafluoropropylene oxide (HFPO) homologues (HFPOs), specifically HFPO-dimeric acid (DA), HFPO-trimeric acid (TA) and HFPO-tetrameric acid (TeA), have emerged as industrial replacements for phased-out perfluorooctanoic acid (PFOA), garnering considerable attention due to their environmental ubiquity and bioaccumulation potential. Nevertheless, the reproductive toxicity of HFPOs remains incompletely characterized, particularly regarding their endocrine-disrupting effect and the underlying mechanisms involving Leydig cell dysfunction. In this study, we investigated the cytotoxic influences of HFPOs on TM3 Leydig cells, focusing on mitochondrial function and dynamics, oxidative stress, and apoptosis. Our findings demonstrated that exposure to HFPOs significantly compromised mitochondrial function and fusion-fission dynamics by disrupting the SIRT1/PGC1α signaling pathway. The mitochondrial dysfunction further triggered excessive ROS production and apoptosis, ultimately impairing TM3 Leydig cell viability and testosterone secretion. However, supplementation with the SIRT1 agonist SRT1720 relieved the inhibitory effect of HFPOs on SIRT1/PGC1α signaling pathway and reversed the expression of apoptosis-associated proteins (BAX/BCL2), oxidative stress-associated proteins (SOD1/SOD2), as well as proteins associated with mitochondrial fusion (MFN2/OPA1) and fission (DRP1/FIS1). These results elucidated the involvement of the SIRT1/PGC1α pathway in mediating the cytotoxicity of HFPOs. Notably, the activation of SIRT1 mitigated HFPO-induced toxicity in the TM3 cells, uncovering its potential in safeguarding testicular cells from the damage caused by HFPOs exposure.
研究领域:
毒理学
·
环境健康
·
内分泌学
·
生殖生物学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Lingjun Zhou,Wenyan Zheng,Muzhi Cai,Feifei Huang,Ying Tian,Shilong Zhao,Liaolin Zhang,Junjie Zhang
The TeO 2 -ZnO-Na 2 O glass system demonstrates significant promise for mid-infrared laser applications due to its high refractive index and low phonon energy, although it is inherently limited by poor thermal stability. Traditional methods aimed at enhancing thermal stability, such as the incorporation of intermediates, typically result in compromised optical performance. However, this study introduces a synergistic optimization strategy through strategic Ta 2 O 5 doping. A systematic analysis utilizing Differential Scanning Calorimetry (DSC), Raman spectroscopy, X-ray Photoelectron Spectroscopy (XPS), and photoluminescence (PL) spectroscopy has uncovered a novel correlation between optical performance and average rather than maximum phonon energy. This discovery provides a refined theoretical framework for the design of tellurite glasses. The optimized Tm 3 -doped TZNT4 glass, with a glass transition temperature ( T g ) of 388 °C and a thermal stability range ( ΔT ) of 137 °C, demonstrates excellent absorption (9.1 ×10 −21 cm 2 ) and emission cross-sections (7.1 ×10 −21 cm 2 ) at 2 μm. This work establishes a structure-property-performance paradigm for tellurite glasses, effectively addressing the critical trade-off between thermal robustness and mid-infrared emission performance through rational composition engineering.
研究领域:
材料科学
·
光学
·
固体物理
·
红外技术
·
玻璃工程
✓ 已验证
产品关联
DOI
高影响因子
Laser & Photonics Reviews
·
2026
·
IF 9.7
Gaixin Zhang,Kejie Li,Jiaqi Zhao,Zhiying Wang,Zuoling Fu
Luminescent materials relying on Yb 3+ or Nd 3+ sensitization often suffer from severe thermal quenching at elevated temperatures, which limits their performance in high-precision ratiometric thermometry and optical encryption. Herein, we report a phonon-tuning strategy in lead-free Cs 2 NaTmCl 6 double perovskite nanocrystals that enables thermal enhancement of Tm 3 + -sensitized luminescence across the visible (450–680 nm) and near-infrared (NIR, 860–1600 nm) regions under 808 nm excitation.Tm 3+ acts as an efficient multi-path sensitizer, facilitating emissions from various lanthanide activators (Nd 3+ , Ho 3+ , Dy 3+ , Yb 3+ , and Er 3+ ). Notably, Tm 3+ -sensitized upconversion emissions of Ho 3+ (∼660 nm) and Nd 3+ (∼600 and 614 nm) exhibit substantial thermal enhancement from 313 to 533 K, with intensity increases of 7.6- and 1.6-fold, respectively, arising from optimized cross-relaxation pathways. In contrast, Tm 3+ -sensitized downshifting NIR emissions from Dy 3+ (∼1320 nm), Yb 3+ (∼980 nm) and Er 3+ (∼1550 nm) are dominated by energy transfer from the Tm 3+ 3 H 4 and 3 H 5 excited states. By exploiting the interplay between activator thermal quenching and Tm 3+ thermal enhancement, highly sensitive NIR-II ratiometric thermometry is achieved, delivering a maximum relative sensitivity of 1.59% K–1 based on the emission bands of Yb 3+ ( 2 F 5/2 → 2 F 7/2 ) and Tm 3+ ( 3 H 5 → 3 H 6 ). This phonon-tuning strategy further provides a broadband temperature-responsive platform for multimodal optical sensing and information encryption.
✓ 已验证
DOI
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2021
·
IF 4.291
Xue Li,Wenting Liu,Jiaojiao Fang,Hengming Huang,Cheng Zhu,Yaru Ni,Liang Fang,Jiahui Kou,Chunhua Lu,Zhongzi Xu
The incorporation of multiple up-conversion (UC) materials into dual-layered UC films presents a promising strategy for achieving multi-peaks spectrum. Here, we developed dual-layered UC films containing triplet-triplet annihilation up-conversion luminescence (TTA-UCL) chromophores and NaYF 4 :Yb 3+ ,Tm 3+ nanoparticles to enable multi-peaks emissions at 340−360 and 390 nm in the transmission manner and 340, 360 and 400–440 nm in the reflection manner under irradiations of green and NIR light. The light absorption and emission behaviors from different film surfaces were studied clearly. Besides, TiO 2 and g-C 3 N 4 with different absorption spectra were chosen to verify the availability of the dual-layered films to tune emission spectra. When both green and NIR light were used simultaneously, TiO 2 and g-C 3 N 4 can degrade tetracycline (TC) by 2.14 and 1.77 times more than the cases where single light was used alone. The photocatalytic abilities of TiO 2 or g-C 3 N 4 can be further improved by the selective increase in NIR or green light power density due to their different absorption spectra. The dual-layered films containing TTA-UCL chromophores and NaYF 4 :Yb 3+ ,Tm 3+ nanoparticles provide a candidate framework for UC systems with tunable short-wavelength spectra to expand their applications in the fields of photocatalysis.
研究领域:
材料科学
·
光催化
·
纳米技术
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MATERIALS CHEMISTRY
·
2011
·Vol. 22
·期 6
·2632-2640
·
IF 5.101
Daqin Chen,Yunlong Yu,Feng Huang,Hang Lin,Ping Huang,Anping Yang,Zhaoxing Wang,Yuansheng Wang
We present a novel strategy involving the lanthanide dopant-induced formation of ultrasmall (sub-10 nm) uniform Ln3+:BaF2/Ln3+:SrF2 active-core/active-shell architectures. The lanthanide ions doped in the shell are demonstrated to play a key role to retard the growth of the core/shell nanocrystals. Particularly, adopting ∼3 nm Tm3+,Yb3+:BaF2 nanocrystals as cores prepared by a solvothermal reaction, growth of Gd3+,Nd3+:SrF2 shells is successfully induced on the surfaces of these cores through a thermal decomposition process, forming ∼7 nm highly uniform and monodisperse Tm3+,Yb3+:BaF2/Gd3+,Nd3+:SrF2 active-core/active-shell nanocubes. In this architecture, the Gd3+,Nd3+:SrF2 shell not only benefits the enhancement of the near-infrared to near-infrared upconversion luminescence of the Tm3+,Yb3+:BaF2 core, but also acts as the host to realize the near-infrared to near-infrared downconversion luminescence of Nd3+ dopants and the paramagnetism of Gd3+ ones. Importantly, the doping of Tm3+/Yb3+ and Nd3+ into the core and shell respectively effectively suppresses the adverse energy transfer from Tm3+ to Nd3+ as well as from Nd3+ to Yb3+, resulting in lessening of the quenching for both Tm3+ upconversion and Nd3+,Yb3+ downconversion emissions. These hydrophobic core/shell nanocrystals are further converted into hydrophilic ones using thioglycolic acid as the surface ligand. The sub-10 nm water-soluble active-core/active-shell architectures with near-infrared to near-infrared dual-modal luminescence and proper paramagnetism may find potential applications in biomedical imaging and detection.
研究领域:
材料科学
·
纳米技术
·
生物医学工程
·
光学
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2026
·
IF 5.4
Bin Yao,Huiyun Luo,Mengdie Qu,Xingyan Liu,Lirong Mo,Panyin Wang,Li Wen,Youzhou He,Yuyu Fang,Min Fu,Bowen Lei
Preparation of upconversion efficient In-TCPP(Zn) via an " internally-empowered " Strategy • Synergistic enhancement of light absorption and charge carrier migration via the upconversion effect and IEF • The IZT has highly efficient photocatalytic production capacity of H 2 . In recent years, most current studies on upconversion photocatalysts mainly focus on improving light harvesting, while their deeper role in regulating charge carrier dynamics remains insufficiently explored. Herein, high-photosensitivity Zn-porphyrin (ZnTCPP) was used as a ligand to synthesize In-TCPP(Zn) (IZT-X%, X represents the content of doped metal salts) doped with upconversion elements (Tm 3+ ). Among the series of synthesized materials, IZT-3% exhibited the most outstanding photocatalytic performance (1775 μmol·g −1 ·h −1 ), which is 8.07 times that of pristine In-TCPP(Zn). In-situ X-ray photoelectron spectroscopy ( in-situ XPS), time-resolved photoluminescence (TRPL), upconversion photoluminescence (UCPL) and DFT analyses reveal that the incorporation of Tm 3+ improves the charge distribution and enhances the built-in electric field (IEF) in In-TCPP(Zn), thereby accelerating charge carrier migration. Simultaneously, Tm 3+ can upconvert low-energy near-infrared (NIR) light to visible light that can be absorbed by In-TCPP(Zn), thereby significantly enhancing its photocatalytic performance. This study highlights the key role of upconversion doping in modulating charge carrier dynamics and provides new insights into the synergistic effect of upconversion and the IEF for improving photocatalytic hydrogen evolution efficiency, thereby broadening the utilization of near-infrared light. Download: Download high-res image (205KB) Download: Download full-size image
✓ 已验证
DOI
高影响因子
JOURNAL OF ETHNOPHARMACOLOGY
·
2020
·
IF 3.69
Wanwan Zhang,Yifang Wei,Xiaoxiao Cao,Kaixin Guo,Qiangqiang Wang,Xiaochun Xiao,Xufeng Zhai,Dingding Wang,Zebo Huang
Ethnopharmacological relevance Crassostrea gigas Thunberg and other oysters have been traditionally used in China as folk remedies to invigorate the kidney and as natural aphrodisiacs to combat male impotence. Aim of the study Erectile dysfunction (ED) has become a major health problem for the global ageing population. The aim of this study is therefore to evaluate the effect of peptide-rich preparations from C. gigas oysters on ED and related conditions as increasing evidence suggests that peptides are important bioactive components of marine remedies and seafood. Materials and methods Crassostrea oyster peptide (COP) preparations COP1, COP2 and COP3 were obtained from C. gigas oysters by trypsin, papain or sequential trypsin-papain digestion, respectively. The contents of testosterone, cyclic adenosine monophosphate (cAMP) and nitric oxide (NO) and the activity of nitric oxide synthase (NOS) in mice and/or cells were measured by enzyme-linked immunosorbent assays. Real-time PCR was used to assess the expression of genes associated with sex hormone secretion pathways. The model animal Caenorhabditis elegans was also used to analyze the gene expression of a conserved steroidogenic enzyme. In silico analysis of constituent peptides was performed using bioinformatic tools based on public databases. Results The peptide-rich preparation COP3, in which >95% peptides were <3000 Da, was found to increase the contents of male mouse serum testosterone and cAMP, both of which are known to play important roles in erectile function, and to increase the activity of mouse penile NOS, which is closely associated with ED. Further investigation using mouse Leydig-derived TM3 cells demonstrates that COP3 was able to stimulate the production of testosterone as well as NO, a pivotal mediator of penile erection. Real-time PCR analysis reveals that COP3 up-regulated the expression of Areg and Acvr2b , the genes known to promote sex hormone secretion, but not Fst , a gene involved in suppressing follicle-stimulating hormone release. Furthermore, COP3 was also shown to up-regulate the expression of let-767 , a well-conserved C. elegans gene encoding a protein homologous to human 17-β-hydroxysteroid dehydrogenases. Preliminary bioinformatic analysis using the peptide sequences in COP3 cryptome identified 19 prospective motifs, each of which occurred in more than 10 peptides. Conclusions In this paper, Crassostrea oyster peptides were prepared by enzymatic hydrolysis and were found for the first time to increase ED-associated biochemical as well as molecular biology parameters. These results may help to explain the ethnopharmacological use of oysters and provide an important insight into the potentials of oyster peptides in overcoming ED-related health issues.
研究领域:
药理学
·
生物化学
·
分子生物学
·
民族药理学
·
海洋生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2016
·
IF 7.145
Pengpeng Lei,Peng Zhang,Shuang Yao,Shuyan Song,Lile Dong,Xia Xu,Xiuling Liu,Kaimin Du,Jing Feng,Hongjie Zhang
Bioimaging probes have been extensive studied for many years, while it is still a challenge to further improve the image quality for precise diagnosis in clinical medicine. Here, monodisperse NaGdF4:Yb3+,Tm3+,x% Bi3+ (abbreviated as GYT-x% Bi3+, x = 0, 5, 10, 15, 20, 25, 30) upconversion nanoparticles (UCNPs) have been prepared through the solvothermal method. The near-infrared upconversion emission intensity of GYT-25% Bi3+ has been enhanced remarkably than that of NaGdF4:Yb3+,Tm3+ (GYT) with a factor of ∼60. Especially, the near-infrared upconversion emission band centered at 802 nm is 150 times stronger than the blue emission band of GYT-25% Bi3+ UCNPs. Such high ratio of NIR/blue UCL intensity could reduce the damage to tissues in the bioimaging process. The possibility of using GYT-25% Bi3+ UCNPs with strong near-infrared upconversion emission for optical imaging in vitro and in vivo was performed. Encouragingly, the UCL imaging penetration depth can be achieved as deep as 20 mm. Importantly, GYT-25% Bi3+ UCNPs exhibit a much higher X-ray computed tomography (CT) contrast efficiency than GYT and iodine-based contrast agent under the same clinical conditions, due to the high X-ray attenuation coefficient of bismuth. Hence, simultaneous remarkable enhancement of NIR emission and X-ray CT signal in upconversion nanoparticles could be achieved by optimizing the doping concentration of Bi3+ ions. Additionally, Gd3+ ions in the UCNPs endow GYT-25% Bi3+ UCNPs with T1-weighted magnetic resonance (MR) imaging capability.
研究领域:
材料科学
·
纳米技术
·
生物医学工程
·
医学成像
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）