Scientific Reports
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2026
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IF 3.9
Zhang Zutao,Xiao Peiyuan,Mei Jinping,Zhang Xinyu,Dai Anni,Wang Lei,Yao Qiufang
Chlorinated pharmaceuticals like diclofenac (DCF) pose persistent environmental risks due to their bioaccumulation and toxicity, necessitating advanced remediation strategies. Herein, an integrated electrochemical system was developed, combining a self-nitrogen-doped carbon nitride (CN)-supported PdNi (CN@PdNi) cathode for electrocatalytic hydrodechlorination (ECH) with a CN anode for oxidative mineralization in a single, sequential process. The CN@PdNi cathode achieved 98.6% ECH efficiency, selectively cleaving C–Cl bonds to mitigate toxicity, which is attributed to its structural merits, including a well-dispersed, albeit partially clustered, nanoparticle distribution, metallic Pd/Ni phases, predominant Pd 0 /Ni 0 states, and enhanced porosity. Subsequent CN anodic oxidation enabled 96.8% total organic carbon (TOC) removal, ensuring near-complete mineralization. Mechanistic studies via Electron paramagnetic resonance (EPR), quenching, LSV, and Tafel slopes revealed atomic hydrogen (*H) generated at Pd 0 sites as the primary reactive species, augmented by electron transfer. The system exhibited robust performance across varied conditions and exceptional stability (< 1% efficiency loss over 11 consecutive cycles). Toxicity assessments showed 3–5 Log 10 unit reductions (ECOSAR) and mung bean germination rates improving from 68.7 to 99.8%. This dual-functional detoxification-mineralization strategy overcomes the limitations of single-step processes and offers a scalable, sustainable solution for efficient remediation of halogenated pollutants.
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高影响因子
BIOSYSTEMS ENGINEERING
·
2019
·
IF 2.983
Chengpeng Xu,Shengying Ye,Xiaolei Cui,Xianliang Song,Xueting Xie
Aflatoxin B1 (AFB1) is the most common and toxic among the aflatoxin group. Improper storage of both raw and processed peanut oil makes it susceptible to AFB1 production. Here, a closed-loop photocatalytic reactor consisting of a glass tube coated with TiO 2 as a catalyst has been developed to study the photocatalytic detoxification of AFB1 in peanut oil. The removal rates of AFB1 in the photocatalytic process were apparently higher than that of the photolysis process. It is inappropriate to approximate Langmuir–Hinshelwood kinetics by a first-order kinetic expression based on the experimental kinetic data for the photocatalytic process. The newly proposed Weibull distribution model provides a good description of the kinetics of the photocatalytic process over the ranges of initial AFB1 concentrations and light intensities studied. The key parameters affecting the detoxification efficiency in terms of the reliable life of this model are described.
研究领域:
食品科学
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环境工程
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化学工程
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毒理学
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高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
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2022
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IF 10.753
Liancheng Fang,Yujing Zhou,Tianming Chen,Yuehan Geng,Zijing Li,Wei Zha,Taozhong Shi,Rimao Hua
Profenofos residues in the environment pose a high risk to mammals and non-target organisms. In this study, the biodegradation and detoxification of profenofos in an efficient degrading strain, Cupriavidus nantongensis X1 T , was investigated. Strain X1 T could degrade 88.82 % of 20 mg/L profenofos in 48 h. The optimum temperature and inoculation amount of strain X1 T for the degradation of profenofos were 30–37 °C and 20 % ( V /V), respectively. Metabolic pathway analysis showed that strain X1 T could degrade both profenofos and its main metabolite 4-bromo-2-chlorophenol. Metabolite toxicity analysis results showed that dehalogenation was the main detoxification step in profenofos biodegradation. The key gene and enzyme for profenofos degradation in strain X1 T were also explored. RT-qPCR shows that organophosphorus hydrolase (OpdB) was the key enzyme to control the hydrolysis process in strain X1 T . The purified enzyme OpdB in vitro had the same degradation characteristics as strain X1 T . Divalent metal cations could significantly enhance the hydrolysis activity of strain X1 T and enzyme OpdB. Meanwhile, strain X1 T could degrade 60.89 % of 20 mg/L profenofos in actual field soil within 72 h. This study provides an efficient biological resource for the remediation of profenofos residual pollution in the environment.
研究领域:
环境微生物学
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生物修复
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酶学
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生态毒理学
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PubMed
高影响因子
Materials
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2022
·Vol. 15
·期 10
·3731
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IF 3.748
Dan Yuan,Shungang Wan,Rurong Liu,Mengmeng Wang,Lei Sun
A novel material of self-shaped ZnO-embedded biomass carbon foam pellets (ZnO@BCFPs) was successfully synthesized and used as fluidized particle electrodes in three-dimensional (3D) electro-peroxone systems for metronidazole degradation. Compared with 3D and 2D + O3systems, the energy consumption was greatly reduced and the removal efficiencies of metronidazole were improved in the 3D + O3system. The degradation rate constants increased from 0.0369 min−1and 0.0337 min−1to 0.0553 min−1, respectively. The removal efficiencies of metronidazole and total organic carbon reached 100% and 50.5% within 60 min under optimal conditions. It indicated that adding ZnO@BCFPs particle electrodes was beneficial to simultaneous adsorption and degradation of metronidazole due to improving mass transfer of metronidazole and forming numerous tiny electrolytic cells. In addition, the process of metronidazole degradation in 3D electro-peroxone systems involved hydroxyethyl cleavage, hydroxylation, nitro-reduction, N-denitrification and ring-opening. The active species of ·OH and ·O2−played an important role. Furthermore, the acute toxicity LD50and the bioconcentration factor of intermediate products decreased with the increasing reaction time.Keywords:electro-peroxone process;particle electrode;metronidazole;degradation mechanism;detoxification
研究领域:
环境科学
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化学工程
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PubMed
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
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2022
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IF 24.319
Haoyang Fu,Meirong Li,Qianyu Xu,Guoliang Chen,Yunjie Zou,Weixian Zhang,Shuzhou Li,Lan Ling
Downsizing supported metal of Fe 0 -based materials in dealing with ever-growing pharmaceutical contamination issues are highly desired but still challenging. Herein, we develop a modular design protocol to synthesize a family of ultrafine alloy nanoclusters embedded in a nitrogen-enriched carbon framework (NEC@FeM (M=Pd, Pt, Au)). Engineering the fine structure of nitrogen-enriched carbon and interfacial interaction with bimetallic nanoclusters largely suppresses bimetallic overgrowth, eventually producing supported ultrafine (< 4 nm), highly dispersed, well-alloyed nanoclusters. The alloying Fe 0 with M for ultrafine nanoclusters optimize the electron flow, chemical stability, and catalytic property, resulting in the obtained NEC@FeM exhibiting excellent doxorubicin (DOX) degradation performance. Density functional theory calculation combined with experimental results attribute the outstanding DOX degradation ability of NEC@FePd originally to the synergistic effect of enhanced DOX affinity and efficient electrons transfer from Fe to DOX. This work provides a paradigm for the design of ultrafine Fe 0 -based nanocluster with application in pollution control.
研究领域:
材料科学
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环境科学
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纳米技术
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药物化学
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DOI
高影响因子
FOOD CHEMISTRY
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2021
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IF 7.514
Chen Su,Yusong Lu,Jinbao Li,Yuxuan Wang,Luqing Pan,Mengyu Zhang
The potential of bile acids (BAs) to reduce aflatoxin B 1 (AFB 1 ) residues and toxicity in Litopenaeus vannamei was evaluated. Both juveniles and subadults were treated with 0, 0.05, 0.15 and 0.25 g/kg BAs for 60 days followed by 10-d AFB 1 exposure (2000 μg/kg), and fifteen shrimp (five shrimp were pooled into one sample, n = 3) from each treatment were collected at five time points (30, 60, 63, 66 and 70 d). All parameters were determined using accepted and standard methods with acceptable accuracy (recovery) of 90–110%. Results demonstrated that BAs reduced the AFB 1 residues in shrimp (limit of detection: 0.01 μg/L, relative standard deviation < 10% and recovery: 92.1–96.8%). BAs increased the detoxification of AFB 1 and decreased the levels of oxidative stress products by increasing Phase II and antioxidant systems, avoiding AFB 1 -induced deterioration of shrimp meat and health risks to human. The confidence level was 95%.
研究领域:
水产养殖学
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食品科学
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毒理学
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PubMed
高影响因子
ENVIRONMENTAL RESEARCH
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2022
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IF 8.431
Caixia Fu,Miao Yan,Zhuoyue Wang,Ji Li,Xiaolei Zhang,Wei Song,Zhiliang Xu,Kalpana Bhatt,Zhongming Wang,Shunni Zhu
The huge application of synthetic dyes caused a severe impact in the environment. In the present study, a physico-chemical strategy of heterogeneous-Fenton catalyzed by the natural ferrous ore has been established for toxic chemical degradation , of which the complex and high-expense repetitive pH adjustment procedures were escaping. And this natural heterogeneous catalyst also could be recycled and sustainable for toxic substances treatment involved in synergetic adsorption and oxidation. The siderite , served as an adsorbent and catalyst for the degradation of methylene blue (MB). Siderite exhibited a better adsorption capacity with a saturated adsorption capacity of ∼11.08 mg/g. Batch adsorption experiments have verified that adsorption rate and adsorption equilibrium followed pseudo-second-order rate model and Langmuir isotherm equation, respectively. The combination with H 2 O 2 , showed significant enhancement of MB degradation without any pH adjustment. The effect of siderite dosage, H 2 O 2 dosage, MB concentration, initial pH, and reaction temperature on MB degradation was investigated, which also has indicated the excellent catalytic performance of siderite. About 99.71% of MB was degraded in 480 min with initial pH of 7.0, reaction temperature of 25 °C, siderite, and H 2 O 2 dosage of 2.5 g/L and 122.38 mM, respectively. It was found that siderite could be reused and remained high degradation efficiency on MB after 5 times reutilization, which also could demonstrate the sustainable and effective process to degrade organic pollution. The generation of reactive species including ·OH and O2·- have been confirmed based on scavenger test and electron spin resonance (ESR) analysis, which was dominated by heterogeneous reaction. The possible degradation mechanisms of MB have been predicted based on spectrum scanning and GC-MS analysis. Moreover, acute toxicity assessment with marine photobacterium Vibrio fisheri was conducted to investigate the toxicity change in the adsorption/oxidation coupled process. This sustainable heterogeneous-Fenton technology has been verified as a promising and applicable process for toxic organic chemicals removal due to effective mineralization and detoxification assisted with the natural ore mineral through the simple operation and mild condtions.
研究领域:
环境科学
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化学工程
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PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2022
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IF 9.136
Ling Cheng,Xianglong Yang,Xiaomei Chen,Chunling Lv,Jin Mao,Qi Zhang,Peiwu Li
A surface oxygen vacancy-engineered WO 3-x film with enhanced photoelectrocatalytic (PEC) activity for the detoxification of deoxynivalenol (DON) was successfully synthesized via an improved sol-gel method. The presence of oxygen vacancy was verified by high-resolution transmission electron microscopy, X-ray photoelectron spectroscopy, X-ray diffraction, Raman spectra and electron spin resonance spectroscopy. The introduction of oxygen vacancy into WO 3-x film substantially enhanced its absorption in visible region, and facilitated its transfer and separation of photogenerated charges. This made the WO 3-x film to have excellent PEC activity for the detoxification of DON under visible light illumination at a low bias of +0.3 V. The percentage of DON removed was up to 86.4 % after being treated with PEC for 2 h. When the bias potential applied was further increased, there were no obvious changes in the degradation efficiency of the film. The cell viabilities were dramatically enhanced with prolonged time, which were over 95 % after 2 h PEC treatment compared to the control. Through the analysis of eight intermediates that were separated and identified by high performance liquid chromatography-mass spectrometry, it can be concluded that the reduction of DON and the cleavage of double bond at C9 C10, epoxy group at C12 13 and hydroxyl group at C3 in DON could greatly reduce the toxicity, and the detoxification mechanism of this PEC system was proposed. This work can provide further insights into DON detoxification using PEC system with low bias.
研究领域:
环境科学
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材料科学
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毒理学
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分析化学
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高影响因子
Agriculture-Basel
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2022
·Vol. 12
·期 10
·1528
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IF 3.408
Shengnan Li,Zedong Wu,Chunhong Liu,Lianxue Fan,Yongheng He,Ke Lu,Dajun Liu,Guojun Feng
Propamocarb is a pesticide widely used to control cucumber downy mildew. The overuse of propamocarb has resulted in residues and phytotoxicity. However, the detoxification and metabolic process of propamocarb have not been documented well. Our previous work showed differences in the propamocarb residues among the different genotypes of cucumber and their regulation by multiple genes. Based on the already reported data on gene expression profiles under propamocarb treatment, we identified the glutathione pathway, including six different genes (Csa4M303130,Csa3M133380,Csa5M409710,Csa7M395820,Csa3M597320, andCsa1M571280), involved in propamocarb detoxification. The qPCR analysis showed thatCsa1M571280(CsGSH2) was most significantly and differentially expressed at 48 h after propamocarb spray in the cucumber varieties Y3F604 (low propamocarb residues) and M729 (high propamocarb residues). In Y3F604,CsGSH2expression increased from 6 to 48 h after spraying propamocarb, and the expression was positively correlated with propamocarb residues, whereas M729 showed no significant difference inCsGSH2expression. Therefore, we presumedCsGSH2as a key gene in managing propamocarb residues. Gene functional analysis showed that propamocarb residues decreased inCsGSH2-overexpressing plants and increased inCsGSH2-antisense plants. Overexpression ofCsGSH2enhanced glutathione (GSH) accumulation and glutathione S-transferase (GST), glutathione reductase (GR), and glutathione peroxidase (GPX) activities, probably for propamocarb detoxification. The activity of antioxidant enzymes (SOD, POD, CAT, and APX) increased to maintain a high antioxidant capacity inCsGSH2-overexpressing plants. The superoxide (O2−), hydrogen peroxide (H2O2), and malondialdehyde (MDA) levels decreased inCsGSH2-overexpressing plants, promoting the antioxidant system composed of ascorbic acid and glutathione (AsA-GSH). Thus, we conclude thatCsGSH2alleviates propamocarb residues and phytotoxicity by enhancing cucumber’s antioxidant and glutathione detoxification potential.Keywords:cucumber;propamocarb;antioxidant;glutathione;detoxification
研究领域:
植物科学
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分子生物学
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农业化学
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高影响因子
Current Nanoscience
·
2019
·Vol. 15
·期 2
·188-196
·
IF 1.586
Xu Chengpeng,Ye Shengying,Cui Xiaolei,Zhang Quan,Liang Yan
Background: Improper storage and raw materials make peanut oil susceptible to Aflatoxin B1 (AFB1). The semiconductor TiO2 photocatalysis technology is an effective technology which is widely used in sewage treatment, environmental protection and so on. Moreover, the photocatalytic efficiency
can be improved by doping I. Method: The experiment is divided into two parts. In the first part, supported TiO2 thin film (STF) was prepared on the quartz glass tube (QGT) by the sol-gel and calcination method and the supported iodine doped supported TiO2 thin film (I-STF) was synthesized
using potassium iodate solution. In the second part, the photocatalytic degradation of AFB1 was performed in a self-made photocatalytic reactor. The AFB1 was detected by ELISA kit. Results: The photocatalytic degradation of AFB1 has been proven to follow pseudo first-order reaction kinetics
well (R2 > 0.95). The maximum degradation rate of 81.96%, which was reached at the optimum iodine concentration of 0.1mol/L, was 11.38% higher than that with undoped STF. Conclusion: The doping of iodine reduces the band-gap of TiO2, thereby increasing the photocatalytic response range.
The proportion of Ti4+ in I-STF has decreased, which means that Ti4+ are replaced by I. The I-STF prepared at iodine concentration of 0.1mol/L has good photocatalytic properties.
研究领域:
食品安全
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环境科学
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材料科学
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化学工程
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高影响因子
JOURNAL OF HAZARDOUS MATERIALS
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2022
·
IF 14.224
Na Chen,Ying Zhao,Meiqi Li,Xiaobing Wang,Xing Peng,Hongwei Sun,Lizhi Zhang
Safe treatment of antibiotics requires efficient removal of both antibiotics and their degraded intermediates. In this study, we demonstrate that FeC 2 O 4 •2H 2 O enables the more sustainable conversion of H 2 O 2 to • OH than commonly used FeSO 4 •7H 2 O, promoting the detoxification of a typical antibiotic sulfadimidine. It was found that the FeC 2 O 4 /H 2 O 2 system could completely degrade 250 mg L −1 of sulfadimidine within 40 min at pH 3.0, along with decreasing the contents of chemical oxygen demand and total organic carbon by 295.0 and 33.5 mg L −1 , respectively, more efficient than those in a classical Fenton system (FeSO 4 /H 2 O 2 ). Analysis of sulfadimidine degraded intermediates and toxicity evaluation suggested that the FeC 2 O 4 /H 2 O 2 treatment could more effectively decrease the overall toxicity of the sulfadimidine solution than the FeSO 4 /H 2 O 2 counterpart. The sustainability of FeC 2 O 4 •2H 2 O in H 2 O 2 conversion to • OH was attributed to its controlled release of Fe 2+ into the solution to prevent the quenching of • OH by excessive Fe 2+ , as well as the simultaneous release of C 2 O 4 2− to complex with Fe 2+ and Fe 3+ , which could inhibit iron sludge formation and accelerate Fe 3+ /Fe 2+ redox cycle. This study provides a promising Fenton system for the safe treatment of antibiotics and sheds light on the potential of FeC 2 O 4 •2H 2 O in environmental remediation.
研究领域:
环境科学
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化学工程
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生物学
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高影响因子
Toxins
·
2016
·Vol. 8
·期 11
·335
·
IF 3.571
Ye Tian,Yanglan Tan,Na Liu,Zheng Yan,Yucai Liao,Jie Chen,Sarah De Saeger,Hua Yang,Qiaoyan Zhang,Aibo Wu
Deoxynivalenol (DON) is a mycotoxin mainly produced by theFusarium graminearumcomplex, which are important phytopathogens that can infect crops and lead to a serious disease calledFusariumhead blight (FHB). As the most common B type trichothecene mycotoxin, DON has toxic effects on animals and humans, which poses a risk to food security. Thus, efforts have been devoted to control DON contamination in different ways. Management of DON production byTrichodermastrains as a biological control-based strategy has drawn great attention recently. In our study, eight selectedTrichodermastrains were evaluated for their antagonistic activities onF. graminearumby dual culture on potato dextrose agar (PDA) medium. As potential antagonists,Trichodermastrains showed prominent inhibitory effects on mycelial growth and mycotoxin production ofF. graminearum. In addition, the modified mycotoxin deoxynivalenol-3-glucoside (D3G), which was once regarded as a detoxification product of DON in plant defense, was detected whenTrichodermawere confronted withF. graminearum. The occurrence of D3G inF. graminearumandTrichodermainteraction was reported for the first time, and these findings provide evidence thatTrichodermastrains possess a self-protection mechanism as plants to detoxify DON into D3G when competing withF. graminearum.Keywords:mycotoxin;toxigenicFusarium;biological control;Trichoderma;modified mycotoxin
研究领域:
植物病理学
·
食品安全
·
微生物学
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PubMed
高影响因子
危险品化学品经营许可证（带存储）