SENSORS
·
2025
·Vol. 25
·期 3
·623
·
IF 3.5
Yuzhen Wang,Ningna Shi,Xiaoyue Kang,Qiliang Pan,Maozhong Tian,Yanfeng Wang,Yunfeng Bai
A sensitive and specific competitive electrochemical immunosensor for the detection of Hg (II) using a modified electrode based on molybdenum disulfide/reduced graphene oxide/gold (MoS2/rGO/Au) nanocomposites was developed in this study. The nanocomposites were characterized and assembled with an antibody against Hg (II) for the immunosensor, demonstrating good electrical activity, high affinity and high specificity. Free Hg (II) in a solution can be measured by the competitive reaction of the Hg element in the sample and the antigen with the antibody fixed on the electrode. A differential pulse voltammetry (DPV) method was used, and the competitive current changed in accordance with the concentration of Hg (II). Under optimal conditions, the sensor showed a linear relationship from 0.1 to 600 ng/mL, and the limit of detection (LOD) was 63 pg/mL. The proposed immunosensor showed an acceptable recovery from 98.4% to 100.3% in spiked samples. Satisfactory stability and reproducibility were obtained. Competitive species, including Zn (II), Mg (II), Al (III), Cu (II), Pb (II), Ba (II), Cd (II), Ag (I), MNA, CH3Hg (I) and CH3Hg-MNA, were selected and applied according to the procedure of the assay, and their significantly different response compared to Hg (II) indicated that the assay displayed not only high sensitivity but also high selectivity. This immunosensor offers a useful model for the detection of Hg (II).
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Mingming Chang,Ruiru Yang,Xiaojing Lai,Xinzhi Wang,Aike Liu,Jing Jiang
Exploiting efficient solar evaporators with photothermic-catalytic bifunctionality has been identified as a reliable strategy for alleviating pollutant enrichment when using organic wastewater as a water source to produce freshwater during solar evaporation. Herein, a new boron-doped molybdenum disulfide (B-MoS 2 ) is introduced as a photoabsorber and catalytic unit to create bifunctional solar evaporator, which demonstrates synergistic process of photothermal conversion and catalytic activation to achieve simultaneous freshwater production and antibiotic destruction in tetracycline (TC)-containing wastewater with peroxymonosulfate (PMS). The B-MoS 2 evaporator displays a superior evaporation rate of ∼ 2.31 kg·m −2 ·h −1 and a high degradation efficiency of 80.7 % within one hour for TC solution under 1-sun irradiation. The combined radical/nonradical pathways are found to dominate the TC degradation, and efficient detoxification is realized over the PMS-coupled B-MoS 2 evaporator. This work provides new avenues to produce freshwater from wastewater sources with the alleviated pollutant enrichment during solar evaporation.
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Frontiers of Chemical Science and Engineering
·
2023
·Vol. 17
·期 12
·2114-2126
·
IF 4.5
Nie Shibin,He Wei,Xu Yuxuan,Zhai Wenli,Zhang Hong,Yang Jinian
In this study, nickel phyllosilicate was synthesized based on molybdenum disulfide (MoS 2 @NiPS) by the sol-gel method, and then MoS 2 @NiPS was used to prepare epoxy composites. The thermal stability, flame retardancy, and frictional performances of epoxy composites were studied. With the addition of 3 wt% MoS 2 @NiPS, the epoxy composite increased the limiting oxygen index from 23.8% to 26.1% and reduced the vertical burning time from 166 s for epoxy resin to 35 s. The residual char of the epoxy composite increased from 11.8 to 20.2 wt%. MoS 2 @NiPS promoted the graphitization of the residual char, and facilitated the formation of a dense and continuous char layer, thereby improving the fire safety of epoxy resin. The epoxy composite with 3 wt% MoS 2 @NiPS had excellent wear resistance property with a wear rate of 2.19 × 10 −5 mm 3 ·N −1 ·m −1 , which was 68.8% lower than that of epoxy resin. This study presented a practical approach to improve the frictional and fire resistance of epoxy composites.
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JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
·
2026
·
IF 2.6
Liu Zhiguo,Miao Xiangqi,Li Junfeng,Bai Shengqi,Chen Yufei,Wang Yue,Jia Zhengfeng,Liu Meng,Zhen Jinming,Zhang Ran
CBP/MoS 2 hybrid filler-reinforced polyethylene glycol (PEG) composites were synthesized via a hydrothermal method in an aqueous PEG solution. These composites demonstrated excellent dispersibility and stability in PEG for tribological evaluation. Test results revealed that lubricants incorporating 2.0 wt.% of the composite material reduced the wear scar diameter (WSD) and coefficient of friction (COF) of steel balls by 48.7% and 41.7%, respectively. This significant enhancement in tribological performance is attributed to a synergistic interaction among PEG, carbon from carbonized bamboo powder (CBP), and MoS 2 . The present study offers a viable strategy for designing high-performance and environmentally sustainable lubricants, while also laying a groundwork for the development of nanoparticle-enhanced water-based lubricating systems.
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International Journal of Nanomedicine
·
2026
·
IF 8.7
Yadong Liu,Yaodong Chen,Shazhou Ye,Jiasheng Hu,Zhong Zheng,Kaining Lu,Wu Chen,Zejun Yan,Xingyi Li
Background: The most challenging clinical characteristic of bladder cancer (BC) is its exceptionally high recurrence rate. Recurrence, metastasis and drug resistance remain critical challenges in BC treatment. Microwave dynamic therapy (MWDT) is an emerging antitumor modality; however, its therapeutic efficacy is limited by the hypoxic tumor microenvironment (TME). To address these limitations, we developed a multifunctional nanoplatform (Mn-Fe-Dox-BSA-MoS2) to enhance oxygenation and therapeutic efficiency. In this system, MoS2 served as a microwave sensitizer and photoacoustic imaging (PAI) agent, while bovine serum albumin (BSA) improved biocompatibility. Doxorubicin (Dox) acted as a chemotherapeutic drug, Mn/Fe ion complexes provided catalase-like activity, and Cy5.5 enabled fluorescence imaging (FI).Methods: Reactive oxygen species (ROS) generation, oxygen production, imaging capability, and microwave/acid-responsive drug release were systematically evaluated. The antitumor efficacy and underlying mechanisms of Mn-Fe-Dox-BSA-MoS2-mediated therapy were further evaluated in MB49 cells in vitro and in BALB/c nude mice in vivo.Results: The nanoflowers exhibited excellent biosafety and efficient microwave sensitization, producing abundant ROS under MW irradiation. Dual-mode FI/PAI imaging enabled precise visualization of tumor accumulation. Mn/Fe complexes catalyzed H2O2 decomposition to continuously generate O2, alleviating tumor hypoxia and enhancing MWDT efficacy. Meanwhile, Dox was effectively delivered and released in response to MW irradiation and acidic TME conditions. The synergistic effects of chemotherapy, MWDT, and microwave thermotherapy (MWTT) significantly inhibited tumor cell proliferation.Conclusion: Mn-Fe-Dox-BSA-MoS2 nanoflowers enable FI/PAI dual-modal imaging-guided multimodal therapy, demonstrating potent antitumor efficacy in a preclinical BC model. MoS subscript 2 is combined with Dox, Mn, Fe and BSA to form Mn-Fe-Dox-BSA-MoS subscript 2. This compound is shown interacting with a cell, enhancing MVDT, MWTT and chemotherapy, leading to tumor cell apoptosis. The process involves ROS enhancement. A mouse model is depicted, indicating the use of this compound for imaging and treatment, with PAI and imaging results shown. The overall process aims at effective tumor treatment and monitoring.Diagram of Mn-Fe-Dox-BSA-MoS2 for tumor treatment and imaging in a mouse model.
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MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 8
·550
·
IF 5.4
Ma Guozhi,Wang Xuan,Cai Jihai,Wang Xiaoying
The rapid detection of Salmonella is an essential precautionary measure to ensure food safety and prevent foodborne illness. In this study, based on the specific binding between mannan oligosaccharides (MOS) and type I fimbriae of Salmonella typhimurium ( S. typhimurium ), an efficient sensing strategy was developed. Obtained by enzymatic hydrolysis of konjac glucomannan, MOS were grafted to mannan-oligosaccharide modified carbon dots (g-CDs-MOS). It is worth noting that the introduction of MOS reduced the dissociation constant (K D ) between fabricated g-CDs-MOS and Con A from 25.4 µM (g-CDs and ConA) to 6.22 µM. This enhanced binding affinity stem from elevated density of MOS on surface of g-CDs. Furthermore, to construct recovery-type fluorescent probe, g-CDs-MOS was bonded onto two-dimensional quencher such as 3-aminobenzeneboronic acid-functionalized graphene oxide (GO-PBA), MnO 2 or MoS 2 . The g-CDs-MOS/MoS 2 exhibited the best sensitivity due to the high electron mobility of MoS 2 . Its fluorescent intensity was logarithmically responsive to concentration of S. typhimurium within the range of 10 2 -10 8 CFU·mL − 1 , and the corresponding limit of detection was as low as 11.79 CFU·mL − 1 . This fluorescent sensor shows promise for the detection of S. typhimurium in food safety. Graphical
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JOURNAL OF MOLECULAR STRUCTURE
·
2025
·
IF 4.7
Shan Huang,Huishan Cao,Chunyan Pan,Xincong Tu,Yi Fang,Qi Xiao,Yue Zhang
This study investigates the interaction mechanism between molybdenum disulfide quantum dots (MoS 2 QDs) and bovine liver catalase (BLC) and its effect on enzyme activity using multispectral analysis and molecular simulations. The results demonstrated that MoS 2 QDs induced noncompetitive inhibition of BLC by binding to its allosteric sites (binding constant: 1.27 × 10 5 L∙mol −1 at 298 K), reducing maximum catalytic velocity with altering the Michaelis-Menten constant. Stable 1:1 non-fluorescent complex formation, primarily driven by van der Waals forces, triggers significant conformational alterations in BLC, including a decrease in α -helix content (from 21.73% to 17.33%) and an increase in random coil structure. Molecular docking identifies 14 binding residues (e.g., aspartate-156, leucine-158, arginine-430) distal to the active site, with a binding free energy of −4.79 kcal·mol −1 . Thermal denaturation studies reveal that MoS 2 QDs reduce the thermal stability of BLC (Δ T m = 5.3 °C). These findings elucidate the machanism bu which MoS 2 QDs inhibit BLC activity through structural perturbation, providing critical insights for the biological safety evaluation of nanomaterials.
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ACS Sustainable Chemistry & Engineering
·
2023
·
IF 8.4
Xiaoxiao Cheng,Yun Tong
Hydrazine oxidation assisting water splitting is considered as a promising strategy toward the highly efficient and energy-saving hydrogen acquirement. However, the development of efficient and stable electrocatalysts for hydrazine hydrate oxidation (HzOR) as well as hydrogen evolution reaction (HER) still remains challenging. In this study, an interface-coupled Co(OH)2/MoS2 nanosheet array is designed to form a synergistic hierarchical heterostructure on a carbon cloth substrate, which is shown to have superior bifunctional performance for HzOR/HER under alkaline conditions. Benefiting from the abundant electrocatalytic active sites and improved reaction kinetics, the Co(OH)2/MoS2/CC electrode shows superior bifunctional performances with low potentials of −134 and 177 mV at 100 mA cm–2 for HER and HzOR, respectively. For the hydrazine-assisted overall water electrolyzer system (OHzS), the Co(OH)2/MoS2/CC electrode delivers low potentials of 142, 197, and 271 mV to realize 10, 50, and 100 mA cm–2, which proves the promising potential application in large-scale preparation of hydrogen fuel. This strategy put forward a simple way toward robust and economic electrodes for energy-related systems.
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DESALINATION
·
2022
·
IF 11.211
Xiaoping Wang,Yanling Liu,Kaiming Fan,Peng Cheng,Huabiao Xia,Shengji Xia
The incompatibility between inorganic nanoparticles and polyamide matrix in thin film nanocomposite (TFN) nanofiltration membranes tends to generate defects in the selective layer and further sacrifice the membrane separation performance, which can be promisingly mitigated by modifying nanoparticles with hydrophilic functional groups. In this study, carboxyl group-grafted molybdenum disulfide (COOH-MoS 2 ) nanoparticles were prepared via organic functionalization grafting reaction and then incorporated into membrane polyamide layers. The resultant TFN membranes exhibited a rougher surface with unique globule structures, which greatly contributed to the enhancement of water permeance . The optimal membrane obtained at the COOH-MoS 2 depositing density of 50.0 μg/cm 2 exhibited a high Na 2 SO 4 rejection of 98.5 %, a low NaCl rejection of 23.8 %, and an excellent water permeance of 27.7 LMH/bar, which was 2.8 and 1.5 times higher than that of the control membrane (9.6 LMH/bar) and the original MoS 2 modified TFN membrane (18.4 LMH/bar), respectively. The more superior membrane performance enabled by COOH-MoS 2 was mainly due to the enhanced hydrophilicity of the nanoparticles, which effectively inhibited the piperazine monomer diffusion and resulted a thinner and properly looser selective layer. This work provides an effective strategy to improve the performance of TFN nanofiltration membranes via graft of proper functional groups on nanomaterials .
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MICROCHIMICA ACTA
·
2023
·Vol. 190
·期 2
·1-12
·
IF 5.7
Zhang Zi-Yang,Xu Yi-Heng,Chen Ke-Yan,Zhang Mei-Hang,Meng Chun-Yan,Wang Xue-Sheng,Wang Man-Man
Benzotriazole UV stabilizers (BUVSs) are a class of emerging contaminants of concern; the development of rapid and convenient monitoring method for these trace-level pollutants in waters is of crucial significance in environmental science. Here, a novel magnetic flower-like molybdenum disulfide/cobalt ferrite nanocomposite (MoS 2 /CoFe 2 O 4 ) was synthesized by hydrothermal reaction. Compared with the conventional Fe 3 O 4 -based magnetic composites, the proposed material just required a minimum consumption of Co/Fe towards the equivalent of MoS 2 while providing superior magnetization performance. Taking advantages of high adsorption capacity, extraordinary stability, and repeatability in construction, MoS 2 /CoFe 2 O 4 was applied to the extraction to BUVSs. The enrichment factors of three BUVSs were in the range 164–193 when 20 mL of environmental water sample was loaded on 40 mg of the adsorbent. MoS 2 /CoFe 2 O 4 could be regenerated and recycled at least 10 cycles of adsorption/desorption with recoveries of 80.1–111%. The method of MoS 2 /CoFe 2 O 4 -based extraction coupled with high-performance liquid chromatography-variable wavelength detector was applied to the monitoring of BUVSs in seawater, lake water, and wastewater, which gave detection limits ( S/N = 3) of 0.023–0.030 ng·mL −1 and recoveries of 80.1–110%. The intra-day and inter-day precisions (relative standard deviation, RSDs, n = 3) were in the range 1.6–7.5% and 3.2–11.5%, respectively. The approach is an alternative for efficient and sensitive extraction and determination of trace-level environmental pollutants in waters. Graphical Abstract
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ENVIRONMENTAL POLLUTION
·
2023
·
IF 8.9
Yuxuan He,Jin Qian,Yuanyuan Li,Peifang Wang,Bianhe Lu,Yin Liu,Yuhang Zhang,Feng Liu
The effect of the molybdenum disulfide (MoS 2 )/levofloxacin (LVF) co-exposure was explored on Phragmites communis and rhizosphere soil bacterial communities. The sequence of MoS 2 /LVF exposure and the different MoS 2 dosages (10 mg/kg and 100 mg/kg) contributed to different degrees of effect on the plant after 42 days of exposure. The treatment with priority addition of low dosage MoS 2 significantly ameliorated P. communis growth, with root length growing up to 532.22 ± 46.29 cm compared to the sole LVF stress (200.04 ± 29.13 cm). Besides, MoS 2 served as an alleviator and reduced the accumulation of reactive oxygen species (ROS) and malondialdehyde (MDA) in P. communis under LVF stress, and activated bacteria in rhizosphere soil. These rhizosphere soil microbes assisted in mitigating toxic pollution in the soil and inducing plant resistance to external stress, such as bacteria genera Bacillus , Microbacterium , Flavihumibacter and altererythrobacter . Potential functional profiling of bacterial community indicated the addition of MoS 2 contributed to relieve the reduction in functional genes associated with amino acid metabolism and the debilitation of gram_negative and aerobic phenotypic traits caused by LVF stress. This finding reveals the effect of different exposure sequences of MoS 2 nanoparticles and antibiotic for plant-soil systems.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2022
·
IF 9.965
Hongqin Liu,Pengfei Tan,Yong Liu,Huanhuan Zhai,Wenna Du,Xinfeng Liu,Jun Pan
The interfacial charge dynamics was crucial for semiconductor heterostructure photocatalysis. Through the rational design of the heterostructure interface, heterojunction expressed variable recombination and migration dynamics for excited carriers. Herein, followed by a typical chemical bath strategy with the hexagonal cadmium sulfide (CdS) overlapped on the exfoliated molybdenum disulfide (MoS 2 ) film, we developed a cadmium sulfide/molybdenum disulfide (CdS-MoS 2 ) nano-heterojunction and investigated the interfacial charge dynamics for photocatalytic hydrogen evolution. Photoelectron spectroscopy detected an energetic offset between CdS and MoS 2 , revealing the formation of an interfacial electric field with efficient charges separation. Through transient absorption spectra, we demonstrated the type-II contact at the CdS-MoS 2 interface. Driven by the electric field, the excited carriers separated and rapidly migrated to sub-band defects of CdS within the first 500 fs. The carriers-restricted defects provided catalytic active sites, endowing CdS-MoS 2 a highly efficient photocatalytic capability. Consequentially, the CdS-MoS 2 achieved an enhanced hydrogen evolution rate of 2.3 mmol·g −1 ·h −1 with significantly stronger photocurrent density. This work gave an insight to the channel of interfacial separation and migration for excited carriers, which could contribute to the interfacial engineering of advanced heterojunction photocatalysts.
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