BIORESOURCE TECHNOLOGY
·
2012
·
IF 4.98
Yongshui Qu,Chongpin Huang,Yanlei Song,Jie Zhang,Biaohua Chen
The dehydration of fructose or glucose to 5-hydroxymethylfurfural (5-HMF) using room temperature ionic liquids (ILs) as a solvent is a promising method for producing liquid fuels from renewable resources . The IL, 1-hydroxyethyl-3-methylimidazolium tetrafluoroborate ([C 2 OHMIM]BF 4 ), was used a catalyst—rather than as a solvent—in the conversion of fructose or glucose to 5-HMF. With glucose, the yield of 5-HMF reached as high as 67.3% after 1 h at 180 °C in dimethylsulfoxide (DMSO) as solvent. The catalyst was separated from the reaction mixture by distilling solvent and reused six times without loss of activity. Furthermore, a kinetic analysis was carried out to illustrate the formation of 5-HMF, and the values of the activation energy and the pre-exponential factor for the reaction were 55.77 kJ mol –1 and 1.6 × 10 4 min –1 respectively.
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JOURNAL OF APPLIED POLYMER SCIENCE
·
2015
·Vol. 132
·期 34
·
IF 1.768
Xiangyan Liu,Deng Hu,Meng Li,Jianming Zhang,Zhigao Zhu,Gaofeng Zeng,Yanfeng Zhang,Yuhan Sun
To improve the pervaporation performance of Silicalite-1/PDMS composite membrane by adding a small amount of Silicalite-1 zeolite, novel Silicalite-1/PDMS surface sieving membranes (SSMs) were prepared by attaching Silicalite-1 particles on the PDMS membrane surface. The obtained membranes and traditional mixed-matrix membranes (MMMs) were characterized by SEM, XRD, TGA, FT-IR, and pervaporation separation of ethanol–water mixture. Effects of Silicalite-1 particles content, feed temperatures, and feed compositions on the separation performance were discussed. From the cross-section view SEM images of SSMs, a two-layer structure was observed. The thickness of the Silicalite-1 layer was about 300 nm to 2 μm. The TGA analysis indicates that the zeolite concentration in 3 wt % SSM is lower than 10 wt % MMMs. In the ethanol/water pervaporation experiment, the separation factor of Silicalite-1/PDMS SSMs increased considerably compared with pure PDMS membrane. When the suspensions concentrations of Silicalite-1 particles reached 3 wt %, the separation factor was about 217% increase over pure PDMS membrane and 52.9% increase over 10 wt % Silicalite-1/PDMS MMMs. As the ethanol concentration in the feed increases, the separation factor of SSMs increases, whereas permeation flux decreases. At the same time, with increasing operating temperature, the permeation flux of SSMs increased. The stability of SSMs at high temperature is better than the traditional MMMs. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132 , 42460.
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NUCLEIC ACIDS RESEARCH
·
2016
·Vol. 45
·期 6
·e45
·
IF 9.202
Zhai Junqiu,Liu Yibin,Huang Shan,Fang Simin,Zhao Meiping
Human apurinic/apyrimidinic endonuclease/redox effector factor 1 (APE1) is an essential DNA repair protein. Herein, we demonstrate that avidin-oriented abasic site-containing DNA strands (AP-DNA) on the surface of silica coated magnetic nanoparticles (SiMNP) can selectively respond to APE1 while resist the digestion by other nucleases. Mechanism studies have revealed that avidin may serve as an organizer protein and recruit APE1 to the DNA substrates on the nanoparticles via strong and specific interactions. Taking advantage of this newly disclosed property, we for the first time successfully displayed the intracellular activities of APE1 in living cells by fluorescence imaging. The avidin organized AP-DNA-SiMNP assembly holds great potential for enzyme-mediated release of drugs inside tumor cells which often contain higher levels of APE1 than normal cells.
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MATERIALS LETTERS
·
2016
·
IF 2.437
Shannan Chang,Cuiping Huang,Huimin Zhang,Aimin Chang
(1− x )BaSn 0.96 Sb 0.04 O 3 – x CoFe 0.5 Co 1.5 O 4 ( x =0.1, 0.3, 0.5, 0.7 and 0.9) composite ceramics had been fabricated through conventional solid-state method. The X-ray diffraction analysis indicated that the composite ceramics consisted of two phases: a perovskite BaSn 0.96 Sb 0.04 O 3 phase and a cubic spinel CoFe 0.5 Co 1.5 O 4 phase. The composite ceramics were more dense and lower porosity with increasing the CoFe 0.5 Co 1.5 O 4 content by SEM. The obtained ρ 25 and B 25/50 constants and activation energy of the composite ceramics were in the range of 1.61×10 5 –1.06×10 6 Ω cm, 1048–8458 K and 0.09–0.729 eV, respectively. In particular, their relationship between R and T which differed from normal NTC displayed a good linear characteristic at 0–200 °C. It could be used expediently in digital instrument and precision measurement.
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BIOSENSORS & BIOELECTRONICS
·
2016
·
IF 7.476
Shuisheng Hu,Wenjun Ouyang,Longhua Guo,Zhenyu Lin,Xiaohua Jiang,Bin Qiu,Guonan Chen
A fluorescent biosensor for ochratoxin A was fabricated on the basis of a new nanocomposite (Fe 3 O 4 /g-C 3 N 4 /HKUST-1 composites). Fe 3 O 4 /g-C 3 N 4 /HKUST-1 was synthesized in this work for the first time, which combined HKUST-1 with g-C 3 N 4 to improve its chemical stability. Fe 3 O 4 /g-C 3 N 4 /HKUST-1 composites have strong adsorption capacity for dye-labeled aptamer and are able to completely quench the fluorescence of the dye through the photoinduced electron transfer (PET) mechanism. In the presence of ochratoxin A (OTA), it can bind with the aptamer with high affinity, causing the releasing of the dye-labeled aptamer from the Fe 3 O 4 /g-C 3 N 4 /HKUST-1 and therefore results in the recovery of fluorescence. The fluorescence intensity of the biosensor has a linear relationship with the OTA concentration in the range of 5.0–160.0 ng/mL. The LOD of sensor is 2.57 ng/mL (S/N=3). This fluorescence sensor based on the Fe 3 O 4 /g-C 3 N 4 /HKUST-1 composites has been applied to detect OTA in corn with satisfying results.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2016
·Vol. 408
·期 22
·6115-6121
·
IF 3.125
Zhang Yun,Yang Hang,Yu Junping,Wei Hongping
In this study, a system of magnetic beads (MBs) coupled with catalytic fluorescent immunoassay for rapid and sensitive determination of HIV-1 capsid antigen p24 was developed. p24 was captured by antibody immobilized MBs, and the detection antibody was linked to horseradish peroxidase (HRP) through biotin–streptavidin recognition, catalyzing the oxidation of o -phenylenediamine (OPD) and hydrogen peroxide to produce a fluorescent product. This is the first reported utilization of the fluorescence of OPD oxidation product catalyzed by HRP for immunoassay. Optimization of conditions afforded a low detection limit of 0.5 pg/mL (3σ) for p24 with a linear range of 1.4–90.0 pg/mL. The assay exhibited good reproducibility with a relative standard deviation (RSD) of 4.4 %, 4.7 %, and 5.0 % for detecting 1.4 pg/mL, 22.5 pg/mL, and 45.0 pg/mL p24, respectively. The assay can be completed in less than 90 min. Moreover, the proposed method was successfully applied to detect p24 in spiked serum. This method overcomes the interference of MBs to the fluorescence signal and demonstrated higher sensitivity for detection of p24 than conventional ELISA kits. The system could be applied for detecting other antigens with high sensitivity, rapidity, specificity, and simple operation.
A rapid and sensitive biosensing method coupling immunomagnetic separation and catalytic fluorescence for determination of HIV-1 p24 has been developed
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JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
·
2016
·
IF 4.179
Peizhu Zheng,Handi Yin,Jihua Zhao,Weiguo Shen
In order to clarify the nature of the inter-micellar interactions, we developed an approach to obtain the intermicellar interaction enthalpy through measuring the mixing heats of dodecyltrimethylammonium bromide (DTAB)/1-dodecyl-3-methylimidazolium bromide (C 12 mimBr) mixed micelles by using flow-mixing calorimetry . It was found that the inter-micellar interaction enthalpies for this system were negative, representing the attractive enthalpy interactions between the mixed micelle droplets. These results are contradictory to those reported in the literature and interpreted by the predominant attractive dehydration effect of counterion. Static light scattering experiment revealed that the repulsive nature of the interaction characterized by the Gibss free energy should be dominated by the entropy interaction.
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JOURNAL OF MOLECULAR LIQUIDS
·
2017
·
IF 3.648
Tian Tian,Xiaoling Hu,Ping Guan,Shuangjie Wang,Xiaoqi Ding
Energetic ionic liquids (EILs) based upon nitrate, perchlorate and dicyandiamide salts of 1-alky/esteryl-4-amino-1,2,4-triazolium are synthesized. The structures are characterized by 1 H NMR, FT-IR and element analysis. The density, constant volume combustion heat and specific heat capacity of these EILs are determined through experiment. Their interaction energies of ion pairs , standard molar volume , standard molar heat capacity and standard molar enthalpy of formation are calculated by DFT/B3LYP/6-311 + G(d,p) and further researched. The thermodynamics function data relative to the reference temperature (298 K) are obtained based on the C p from 303 to 353 K. The influences of temperature, molecular structure and interaction energy of ion pairs on ρ and C p are also discussed systematically. In addition, the density and thermodynamic properties of EILs are deduced from theoretical calculation and experimental evidences. As a result, the physicochemical properties estimation of EILs using theoretical calculation method can be applied in the field of modern military, science, etc.
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RSC Advances
·
2017
·Vol. 7
·期 77
·48526-48536
·
IF 3.108
Qian Zeng,Jinwei Zhang,Hongye Cheng,Lifang Chen,Zhiwen Qi
Ionic liquids (IL) become more promising in industrial applications, especially in desulfurization processes. It is of great importance to investigate their corrosivity to steel and the effect of steel corrosion on desulfurization performance. In this work, the corrosion behavior of two typical metals, namely mild steel and stainless steel, in 1-butyl-3-methylimidazolium hydrogen sulfate ([BMIM]HSO4) IL systems for desulfurization application were investigated by weight loss and surface analyses. The model oil can inhibit the IL corrosivity, while the presence of water or H2O2 enhances the corrosion degree. The bonding information of [BMIM]HSO4 adsorbed on a steel surface was confirmed using ATR-FTIR. It was found that the IL film is mainly adsorbed on the metal surface by the interaction of the imidazolium group of the cation and HSO4− of the anion with the steel surface. From the ICP-MS and Raman analyses, the primary component of corrosion products is iron sulfate (ferric sulfate for mild steel and ferrous sulfate for stainless steel). Localized corrosion (pitting and/or intergranular corrosion) appears on steel surface from SEM observation, which could be a serious safety risk to the [BMIM]HSO4-based desulfurization systems for industrial application. The corrosion has a side effect on the desulfurization performance of [BMIM]HSO4.
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RSC Advances
·
2017
·Vol. 7
·期 51
·32336-32343
·
IF 3.108
Ying Zhou,Lanting Zeng,Yinyin Liao,Fang Dong,Qiyuan Peng,Jianlong Li,Jinchi Tang,Naoharu Watanabe,Ziyin Yang
Insect attacks change the quantity of volatiles emitted from plants, but little is known about the effects on the volatiles' stereochemical configurations. 1-Phenylethanol (1PE) is a major internal volatile of tea (Camellia sinensis) flowers. In the present study, insect-damaged C. sinensis flowers in the field emitted a different (R)-/(S)-1PE pattern than that emitted from undamaged flowers. Laboratory experiments showed that changes in the (R)-/(S)-1PE ratio were caused by treatments with Thrips hawaiiensis (Morgan), a pest of cut flowers and vegetable crops. These treatments led to an increase in jasmonic acid (JA) through the activation of allene oxide synthase, which is involved in JA biosynthesis. Exposing flowers to exogenous JA induced an (R)-/(S)-1PE emission pattern that was similar to that induced by a T. hawaiiensis attack, suggesting that JA was involved in the changes in the stereochemical configuration of 1PE emitted from the flowers after insect treatments. This study provides new insights into the involvement of volatiles in interactions between plants and insects, showing that not only the quantity but also the stereochemical configuration of plant volatiles is affected by insects.
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JOURNAL OF CHEMICAL THERMODYNAMICS
·
2016
·
IF 2.196
Li Wan,Hengde Li,Cheng Huang,Yuqing Feng,Guoqiang Chu,Yuying Zheng,Wei Tan,Yanlin Qin,Dalei Sun,Yanxiong Fang
Linalool and geraniol are the primary components of rose oil, palmarosa oil, and citronella oil and many other essential oils, and two important compounds used in the flavour and fragrance, cosmetic or pharmaceutical industries. Phase equilibria (LLE, VLE, solubility, etc. ) and related thermodynamic properties of a mixture are essential in the processes design and control of mass transfer process. In this work, experimental (liquid + liquid) equilibria data of the systems (water + 1-propanl + linalool) and (water + 1-propanl + geraniol) are presented. The (liquid + liquid) equilibria of both systems were determined with a tie-line method at T = (283.15, 298.15 and 313.15) K under atmospheric pressure. The well-known Hand, Bachman and Othmer–Tobias equations were used to test the reliability of the experimental values. The influence of the temperature on the (liquid + liquid) phase equilibria of the mixtures, the binodal curves and distribution ratios of 1-propanl are shown and discussed. Moreover, the NRTL and UNIQUAC models were applied to fit the data for both ternary systems. The interaction parameters obtained from both models successfully correlated the equilibrium compositions. Furthermore, the ternary systems could be represented using the binary parameters of the thermodynamic model with a function of temperature.
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BIOMEDICINE & PHARMACOTHERAPY
·
2012
·
IF 2
Lan Qian,Di Xiang,Jing Zhang,Shunying Zhu,Jin Gao,Xia Wang,Jing Gao,Yang Zhang,Jiaqing Shen,Yan Yu,Wei Han,Mingyuan Wu
Cyclophosphamide (CY), targeting to fast dividing cells, results in bone marrow (BM) suppression, which is the most common side effect of cancer chemotherapy . Interleukin-1 receptor antagonist (IL-1Ra), activated by variety of chemotherapeutic drugs, is a natural inhibitor of interleukin-1 (IL-1) and blocks the functional IL-1 receptor signaling. Our previous studies showed the protective effect of recombinant murine IL-1Ra on hematopoiesis in mice after treatment with chemotherapeutic agent 5-fluorouracil. In this report, we demonstrate that the pretreatment use of recombinant human IL-1Ra (rhIL-1Ra) significantly alleviated chemotherapy-induced peripheral blood injury in mice, and reduced the incidence and severity of neutropenia in beagle dogs. Moreover, acute lethal toxicity in single and repeated CY treatment was markedly reduced by rhIL-1Ra administration. The chemoprotective role of rhIL-1Ra is attributed to the attenuated BM damage, accelerated recovery of BM cells , and enhanced survival of hematopoietic progenitor cells which expressed high level of aldehyde dehydrogenase and IL-1 receptor type I. Thus, our data strongly suggest that the prophylactic use of exogenous rhIL-1Ra renders BM primitive hematopoietic cells resistant to chemotherapy, which provides novel strategies to prevent BM suppression in clinical settings.
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