JOURNAL OF MOLECULAR LIQUIDS
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2018
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IF 4.513
Bincheng Xu,Huaili Zheng,Hui Zhou,Yongjuan Wang,Kun Luo,Chun Zhao,Yu Peng,Xinyu Zheng
In this work, a novel chitosan-based magnetic adsorbent [poly(2-(dimethylamino)ethyl methacrylate) grafted magnetic chitosan microspheres , GMCMs] was synthesized by graft polymerization of (2-(dimethylamino)ethyl methacrylate on the surface of magnetic chitosan microspheres (MCMs). The as-prepared GMCMs exhibited significantly enhanced adsorption capacity towards anionic dyes (e.g., Acid Green 25 and Reactive Blue 19) compared with MCMs. It is due to the fact that the abundant tertiary amine groups of the grafted polymer protonated at low pH and the polymer chains stretched as a result of electrostatic repulsions and chain-solvent interactions. The stretched polymer chains provided a variety of adsorption sites, which efficiently adsorbed dyes through electrostatic interactions and hydrogen bonding . While, in alkaline conditions, the tertiary amine groups were deprotonated and the polymer chains collapsed due to hydrophobic interactions, which facilitated the regeneration of the dye-loaded GMCMs at high pH. The regenerated GMCMs showed excellent adsorption performance even after five adsorption–desorption cycles. Besides, the GMCMs could be rapidly separated from aqueous solutions under an external magnetic field. Therefore, the GMCMs materials bear great application potentials in water treatment owing to its high adsorption capacity, pH-responsiveness, facile regeneration and good reusability.
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ACS Biomaterials Science & Engineering
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2018
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IF 4.432
Ying Duan,Ruiping Duan,Rui Liu,Man Guan,Wenjuan Chen,Jingjing Ma,Mingmao Chen,Bo Du,Qiqing Zhang
Biocompatible, near-infrared luminescent gold nanoclusters were synthesized in situ using as-prepared chitosan grafted with N-acetyl-l-cysteine (NAC-CS). The fluorescent gold nanoclusters coated with chitosan-N-acetyl-l-cysteine (AuNCs@NAC-CS) were aggregated by multiple ultrasmall gold nanoclusters closing with each other, with strong fluorescence emission at 680 nm upon excitation at 360 nm. AuNCs@NAC-CS did not display any appreciable cytotoxicity on cells even at a concentration of 1.0 mg mL–1. AuNCs@NAC-CS were more insensitive to H2O2 and trypsin compared with fluorescent gold nanoclusters coated with Albumin Bovine V (AuNCs@BSA), which make them have long time imaging in HeLa cells. Furthermore, the obvious fluorescence signal of AuNCs@NAC-CS appeared in the liver and kidney of the normal mice after 6 h injection. And the fluorescence intensity decreased after that because of the highly efficient clearance characteristics of ultrasmall nanoparticles. These findings demonstrated that AuNCs@NAC-CS possessed good fluorescence, low cytotoxicity, and low sensitivity to some content of cells, allowing imaging of the living cells.
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JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY
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2018
·Vol. 93
·期 9
·2691-2700
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IF 2.587
Zhuqing Wang,Pengxiang Jin,Min Wang,Genhua Wu,Jiayin Sun,Yujie Zhang,Chen Dong,Aiguo Wu
BACKGROUND In this study, a low-cost and environment-friendly alginate–chitosan hybrid adsorbent (depicted as Alg-Chi) was developed for the removal of Pb 2+ from water. RESULTS Experimental results showed that the Alg-Chi exhibits high selectivity and affinity for Pb 2+ . The selectivity coefficients of the Alg-Chi for Pb 2+ /Cr 3+ , Pb 2+ /Co 2+ Pb 2+ /Cd 2+ , Pb 2+ /Zn 2+ , and Pb 2+ /Cu 2+ are all >5. It can uptake 96.8% of Pb 2+ from Pb 2+ -containing solutions (1.5 mmol L −1 ), and the maximum adsorption capacity for Pb 2+ reaches 468.5 mg g −1 , which is higher than that of most reported adsorbents for Pb 2+ . Moreover, the Alg-Chi can also be regenerated via simple acid elution and used repeatedly without loss in adsorption ability. CONCLUSIONS Analysis of the adsorption mechanism indicated that the Alg-Chi adsorbed Pb 2+ mainly through ion exchange and chemical coordination. Green and low-cost raw materials, simple preparation process, efficient removal efficiency and recyclable, these characteristics give the synthetic Alg-Chi broad application prospects in the field of Pb 2+ -containing wastewater treatment. © 2018 Society of Chemical Industry
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JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
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2024
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IF 3.3
Huiyun Zhang,Xinling Li,Ziye Zhang,An Jiang,QiaoQiao Bai
BACKGROUND Previous studies have demonstrated that the addition of chitosan can improve the quality and functional properties of meat products. However, the underlying mechanism remains unclear. In this study, the effect and mechanism of the addition of chitosan on the gel properties of myofibrillar protein (MP) were investigated. RESULTS The results indicated that the gel strength and the water-holding capacity of MP-chitosan gel increased significantly when chitosan was added at 2.5–10 mg mL −1 . Myofibrillar protein samples with 10 mg mL −1 added chitosan exhibited the highest elasticity and viscosity during gel formation and strengthening. The addition of chitosan also caused a modification in both the secondary and tertiary structure of MP, resulting in an enhanced exposure of hydrophobic and sulfhydryl groups in comparison with the control. Chitosan inhibited the conversion of immobilized water into free water and the formation of water channels during the thermal gelation process of MP. The denaturation enthalpy ( Δ H) of myosin decreased as the concentration of chitosan exceeded 5 mg mL −1 . The microstructure showed that the incorporation of chitosan (5–10 mg mL −1 ) facilitated the formation of compact and well organized MP gel networks. CONCLUSION The addition of chitosan can enhance the functional properties of meat protein and facilitate heat-induced gelation, making it a promising ingredient for improving the quality of processed meat products. © 2024 Society of Chemical Industry.
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Polymer-Plastics Technology and Materials
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2024
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IF 2.6
Lu Guo,Shiwei Wang,Weizhen Xie,Xuan Wu,Bo Zhao,Man Liu,Chaolu Yin,Qian Li
In order to improve the thermal insulation and smoking properties of expanded vermiculite matrix composites, a kind of expanded vermiculite (EV)/chitosan (CS) composites was prepared by hot pressing. The effects of CS on smoke density, fire-resistance, insulation, and mechanical properties of the EV/CS composites were studied. The results show that with the increase of CS content, the smoke absorption performance and energy storage modulus of the composites is improved. Thermogravimetric (TG) analysis shows that the thermal stability of the EV/CS composite is improved by the presence of chitosan. The pores appear on the surface of the composites after the single-side fire-resistance test. After that, the thermal conductivity of the composites gradually decreases and the insulation performance is improved as the CS content increases. The CS carbonized during the preparation of the composites and thermal decomposition during the test. The morphology results show phase separation of the composites, and the porosity of the composites increases after the test. The reticular structure formed between the EV particles, sodium silicate, and CS molecules reduces the strength loss of the composites.
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CARBOHYDRATE RESEARCH
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2024
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IF 2.4
Xuerong Luo,Lingyu Zhao,Imran Mahmood Khan,Lin Yue,Yin Zhang,Zhouping Wang
Curcumin (Cur) is a naturally hydrophobic polyphenol, and it has a wide range of physiological functions. But the practical application of Cur is constrained by its low water solubility and poor stability. To improve these deficiencies of Cur, a novel Cur derivative (CS-Cur) was prepared by grafting chitosan (CS) with Cur through a one-step reaction of a free radical-mediated redox system. A series of characterizations provided evidence that the grafting of CS with Cur was successful. The obtained CS-Cur showed lower crystallinity and thermal properties than CS and Cur. After grafting, the water solubility of CS-Cur was found to be 9.76 ± 2.45 g/L and greatly improved. Meanwhile, the CS-Cur showed good photothermal stability, antioxidant activity, and photodynamic antibacterial activity in an aqueous solution, and it had good in vitro biosafety. This provides an idea for the design and synthesis of novel highly water-soluble Cur derivatives and also improves the practical application of Cur in aqueous systems.
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LANGMUIR
·
2025
·
IF 3.9
Shi-Hao Yang,Xue Zhang,Yu-Mei Tan,Rui Xie,Wei Wang,Zhuang Liu,Da-Wei Pan,Xiao-Jie Ju,Liang-Yin Chu
The controllable fabrication and performances of monodisperse genipin-cross-linked gelatin–chitosan composite (GGC) embolic microspheres with both uniform sizes and adjustable characteristics of elasticity and degradation are reported for the first time. Monodisperse emulsion droplets are fabricated as templates by using gelatin and chitosan aqueous solution as the disperse phase in a microfluidic device, and the chemical cross-linking of gelatin and chitosan inside droplet templates is achieved with genipin that transfers from the collection bath into the droplets. The sizes of droplet templates and the resultant GGC microspheres can be flexibly controlled and predicted by adjusting the fluid flow rates and the device dimensions. The elastic property of GGC microspheres can be flexibly regulated by adjusting the molar ratio of gelatin/chitosan in the disperse phase. The in vitro degradation-caused dynamic volume shrinkage of GGC microspheres can be flexibly regulated by adjusting the molar ratio of gelatin/chitosan, the chitosan deacetylation degree, and the enzyme concentration in degradation solution. Based on the Box–Behnken design-response surface method, a second-order equation is developed for the first time to predict the in vitro degradation-caused dynamic volume shrinkage ratios of microspheres prepared with different molar ratios of gelatin/chitosan and different chitosan deacetylation degrees in degradation solutions with different enzyme concentrations. The fabricated GGC microspheres show good repeatable embolization performances in an in vitro embolization chip system. The results of this study provide valuable guidance for controllable fabrication of degradable microspheres with both uniform sizes and on-demand elastic and degradation characteristics for efficient application in embolization therapy.
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JOURNAL OF MOLECULAR LIQUIDS
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2025
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IF 5.2
Li Yaqi,Dai Yimin,Cai Ling,Yang Siwen,Wang Junlong,Liu Bo,Ding Xianglong,Zhang Yue-Fei,Li Yan,Lu Cuihong,Wan Li
Using aniline and environmentally friendly chitosan as raw materials, MnFe 2 O 4 with photocatalytic properties was introduced and in-situ polymerization was used to prepare Cht/PANI/MnFe 2 O 4 . The Cht/PANI/MnFe 2 O 4 was characterized by FTIR, SEM, XPS, XRD, BET and TGA. The experiment on the influence of pH on the adsorption capacity of the material shows that an acidic environment is conducive to the adsorption of fuel by the adsorbent. The zero charge point (pH PZC ) on the adsorbent surface is obtained at pH 6.45. The adsorption kinetic model conformed to the pseudo second order model, and the adsorption isotherm was in agreement with the Langmuir isotherm model. The q max values of Cht/PANI/MnFe 2 O 4 and Cht/PANI were 202.84 and 148.37 mg·g −1 . Experimental results have shown that Cht/PANI/MnFe 2 O 4 exhibits photocatalytic performance, which is superior to pure MnFe 2 O 4 .The maximum removal amount of Cht/PANI/MnFe 2 O 4 at equilibrium is 2569.66 mg·g −1 . The photocatalytic process of Cht/PANI/MnFe 2 O 4 also conforms to the pseudo-second-order kinetic model. The material has the advantages of simplicity and environmental friendliness and has potential application prospects in the purification of dye wastewater. The study proposed possible mechanisms for the adsorption and photocatalysis of CR.
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CARBOHYDRATE POLYMERS
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2024
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IF 10.7
Dong Xiang,Kunlan Wang,Feilong Wang,Yan Li,Yulin Hou,Kun Hu,Yongxiang Xu
Uncontrolled non-compressible hemorrhage, which is often accompanied by coagulopathy, is a major cause of mortality following traumatic injuries in civilian and military populations. In this study, coagulopathy-independent injectable catechol-modified chitosan (CS-HCA) hemostatic materials featuring rapid shape recovery were fabricated by combining controlled sodium tripolyphosphate-crosslinking with hydrocaffeic acid (HCA) grafting. CS-HCA exhibited robust mechanical strength and rapid blood-triggered shape recovery. Furthermore, CS-HCA demonstrated superior blood-clotting ability, enhanced blood cell adhesion and activation, and greater protein adsorption than commercial hemostatic gauze and Celox. CS-HCA showed enhanced procoagulant and hemostatic capacities in a lethal liver-perforation wound model in rabbits, particularly in heparinized rabbits. CS-HCA is suitable for mass manufacturing and shows promise as a clinically translatable hemostat.
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ELECTROANALYSIS
·
2024
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IF 2.7
Jianrong Wang,Luhua Wang,Hongfang Zhao,Hongxia Li,Xiaohui Niu,Yi Wang,Kunjie Wang
Polysaccharide materials have wide applications in the field of chiral recognition. Herein, a new series of chiral materials based on chiral polysaccharide were synthesized for electrochemical enantioselective recognition of tryptophan (Trp) enantiomers. Chiral recognition was investigated via differential pulse voltammetry (DPV). Among poly (L-lactide) La/hydroxyapatite chitosan (PLLHC-X) series materials (PLLHC-0, PLLHC-1, PLLHC-3, PLLHC-7 PLLHC-9 and PLLHC-5), PLLHC-5 has the best recognition efficiency. And the results reveal that the PLLHC-5 displays a stronger interaction with L-Trp than to that of D-Trp. The synergetic effect of chiral recognition from chitosan and signal amplification from poly (L-lactide) (PLLA) offered an easy-handling and effective electrochemical approach for isomers discrimination to realize the chiral recognition of Trp enantiomers. The synergetic effect results in highly efficiency and thus opens up new directions in the field of chiral materials.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
·
IF 7.7
Yajie Zhong,Libin Dong,Jiao Li,Farzad Seidi,Guofu Li,Huining Xiao
Chronic wounds, particularly those with non-healing ulcers, show high levels of oxidant stress, such as excessive reactive oxygen species (ROS), which delays the healing process. Bacterial infections in wounds increase the need for antibiotics, which brings up serious concerns regarding antibiotic resistance. The innovative antibiotic-free strategies to endow the hydrogels with antibacterial and antioxidant features including the grafting of ROS-scavenging moieties onto the hydrogel structure are in high demand for wound management. Herein, an antibacterial and antioxidant hydrogel with rapid self-healing performance was fabricated via the dynamic borate ester cross-linkages between catechol-grafted chitosan (CS-CA) and polyvinyl alcohol in the presence of borax with the incorporation of ellagic acid (EA). Benefiting from the catechol groups from EA and CS-CA, the resulting hydrogel exhibited desirable adhesive property, excellent antioxidant and intensified antibacterial dual functions. Furthermore, the hydrogel demonstrated remarkable biocompatibility and pH-responsive behavior for the controlled release of EA, attributed to the reversible characteristics of borate ester linkages. Notably, these multifunctional hydrogels exhibited substantial regenerative capabilities in wound healing, as evidenced by in vivo assessments conducted on a full-thickness skin defect model, highlighting their considerable potential as wound dressings for effective wound management.
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CARBOHYDRATE POLYMERS
·
2024
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IF 10.7
Lijian Cai,Yutong Chen,Zetan Lu,Ming Wei,Xin Zhao,Yanjun Xie,Jian Li,Shaoliang Xiao
Developing bio-based sustainable wood adhesives is significant as a substitute for petroleum-derived adhesives. However, the existing bio-based adhesives have disadvantages of complex fabrication, uncontrollable viscosity, and poor water resistance. Herein, we developed a citric acid/chitosan adhesive with viscosity-controlled and water-resistant features by one-step dissolution at room temperature based on the supramolecular self-assembly strategy. Different wood products (plywood, laminated veneer lumber and particleboard) with superior performance were prepared by applying that adhesive on veneer and wood particles (fine and rough particles). The plywood test results showed that the citric acid/chitosan adhesive had dry and wet shear strengths outperforming the China National Standard (GB/T 9846-2015, ≥0.7 MPa), reaching 2.1 and 1.1 MPa, respectively. The adhesion mechanism was mechanical interlocks and cross-linking of citric acid/chitosan in adhesives with those in the cell wall. This work provides high promise for alternatives to traditional unsustainable wood adhesives (urea-formaldehyde, melamine-urea-formaldehyde and phenolic resins) for fabricating different wood products.
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