IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
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2026
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IF 7
Chen Liu,Xue Zhou,Hanyu Bai,Yana Zhang,Yong Zhao,Xuegang Li
Beta-actin (ACTB), a highly conserved cytoskeletal protein, is frequently dysregulated in early-stage malignancies, making its sensitive and specific detection crucial for cancer screening. Here, we develop a reflective fiber-optic SPR biosensor functionalized with copper–glycine engineered WS₂ nanosheets for label-free ACTB detection. The Cu–glycine modification not only enables WS₂ surface amination for efficient antibody conjugation, but also introduces Cu²⁺-mediated near-infrared absorption to amplify the plasmonic resonance response. Combined with the intrinsically large surface area and high refractive index sensitivity of WS₂, this synergistic design markedly enhances both molecular binding and signal transduction. The resulting WS₂-NH₂-based sensor achieves a refractive index sensitivity of 1467.5 nm/RIU, representing a 1.67-fold enhancement over unmodified fiber probes. For ACTB detection, it delivers an ultralow detection limit down to 9.766 pM, a broadened linear range of 2.4–120 pM (5×expansion), and a biosensing sensitivity of 84.477 nm/nM (1.4× improvement). Furthermore, at 1 ng/mL, a rapid response time of 20 min is achieved, demonstrating applicability for trace-level biomarker screening. Integrating high sensitivity, broad dynamic range, amplified spectral response, and strong anti-interference capability, this plasmonic WS₂-NH₂-modified fiber platform enables highly selective, label-free ACTB quantification. These findings highlight its strong potential for early cancer diagnosis, biomarker monitoring, and precision medical applications.
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JOURNAL OF HAZARDOUS MATERIALS
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2026
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IF 10.6
Jiabai Cai,Wenjia Huang,Jieyi Gong,Jiaqing Huang,Huan Li
Catalytic air oxidation of refractory organic wastewater often faces limitations such as low efficiency and high energy consumption. Herein, by encapsulating size-tuned copper nanoparticles (NPs) within porous Al 2 O 3 and finely optimizing the associated Cu(I)/Cu(II) ratio, we realized a catalytic mechanism that synergistically leveraged spatial confinement and a low-temperature thermal induction effect (LTIE). Porous-Al 2 O 3 -enabled spatial confinement improved surface crystallinity and effectively suppressed copper NPs aggregation. Compared to the high energy required by gas-phase O–O bond homolysis (∼5.16 eV), O–O activation on the Al 2 O 3 @Cu catalyst required dramatically less energy (∼0.1 eV) owing to efficient charge transfer. Under low-temperature conditions, the LTIE promoted hot-electrons generation and transfer, thereby enabling the cascade production of reactive oxygen species (including · OH, · O 2 ⁻, and 1 O 2 ), resulting in exceptional performance in the catalytic air oxidation of refractory organic pollutants. In batch experiments, the LTIE caused an 86% reduction in ultraviolet absorbance at 254 nm for actual biogas slurry at 90°C within 5 h. Further, a continuous bench-scale system demonstrated an average chemical-oxygen-demand removal rate of 92%, compliant with wastewater treatment standards. This study presents an efficient strategy integrating spatial confinement, electron transfer, and thermal activation to achieve complete mineralization of refractory organic pollutants in wastewater.
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MICROCHEMICAL JOURNAL
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2026
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IF 5.2
Li Wang,Liwei Wang,Yuhang Que,Ling Xin,Fugang Xu
Donut-like Cu-Zn-MOF@CuNPs were synthesized via facile two-step approaches. • Cl − amplifies Cu signal via formation of highly electroactive CuCl. • Ag + inhibits the signal by competitive binding with Cl − to form AgCl. • The sensor detects Ag + with a low LOD of 1.4 nM and wide linear range. • It shows good selectivity, stability, and real water sample recovery. Silver ions (Ag + ) are highly toxic heavy metal pollutants. Conventional electrochemical methods for Ag + detection typically involve complex ionophore preparation, long preconcentration/stripping steps, or costly biorecognition agent. Here, we report a Cu-Zn-MOF supported CuNPs composite (Cu-Zn-MOF/CuNPs) for Ag + detection. The composite is prepared via a two-step room temperature mixing process. The nest-like Cu-Zn-MOF, composed of stacked two-dimensional nanosheets, provides a high specific surface area and accessible active sites for CuNPs deposition, which improves conductivity and generates a detectable redox signal. The presence of Cl − enhances the Cu redox signal due to the formation of electroactive CuCl. In the presence of Ag + , this signal enhancement is suppressed due to the competitive binding that forms AgCl precipitates. Leveraging this “amplification-inhibition” response, the Cu-Zn-MOF/CuNPs modified electrode allows for Ag + detection with two linear ranges (5 nM–100 nM and 100 nM–1100 nM), a detection limit of 1.4 nM, and recoveries ranging from 96.5% to 104.5% in spiked real water samples. The preparation procedure and detection protocol are relatively straightforward, and the sensing mechanism offers an alternative pathway for heavy metal ion detection. A donut-like Cu-Zn-MOF/CuNPs composite enables sensitive and selective electrochemical detection of Ag + via a novel amplification-inhibition mechanism: Cl − enhances the Cu redox signal through CuCl formation, while Ag + competitively binds Cl − to suppress the signal. The sensor achieves a low detection limit of 1.4 nM and good performance in real water samples. Download: Download high-res image (121KB) Download: Download full-size image
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Catalysts
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2025
·Vol. 15
·期 7
·623
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IF 4
Caidong Du,Wenwei Wu,Jiangtao Shang,Keyi Xiang
Methane (CH4) has attracted much attention regarding its use in electrochemical carbon dioxide reduction reaction (CO2RR) due to its high mass-energy density; however, the uneven adsorption of intermediates on copper sites by conventional Cu-based catalysts limits the selective production of CH4. The introduction of a second metal can effectively regulate the adsorption energy of intermediates on the Cu site. In this paper, a method of alloying Cu with oxyphilic metals (M) using rapid electrodeposition is presented; the synergistic effect of the bimetal effectively directed the reaction pathway toward CH4. The best Faraday efficiency for methane occurred in the optimized Cu30La20electrode, reaching 66.9% at −1.7 V vs. RHE potential. In situ infrared testing revealed that the *CHO intermediate—a critical species for the electrocatalytic conversion of CO2to CH4—was detected on the Cu30La20catalytic electrode. However, no *CHO intermediate was observed on the Cu20La30electrode. Instead, the characteristic peak of the *OCCHO intermediate associated with C-C coupling emerged on the Cu20La30catalyst. This indicates that the adsorbed oxygen-containing groups on lanthanum sites reacted with carbon-containing groups on copper sites to form C2products, serving as the primary reason for the shift in reduction products from methane to ethylene.
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Journal of Materials Chemistry C
·
2025
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IF 5.1
Doan Thi Luu Luyen,Dinh Chuong Nguyen,Dat Ngoc Trinh,Son Vu Truong Le,Soon-Gil Yoon,Nguyen V. Hieu
Rationally designed electrocatalysts with excellent catalytic activity and robust stability are essential for enhancing the performance of water splitting toward a near-future hydrogen economy. In this work, we report a highly efficient triphase hetero-interface heterostructured electrocatalyst consisting of ultrafine Rh nanoparticles anchored on Cu3P/MnP nanosheets supported on Ni foam (labelled Rh/Cu3P/MnP) to boost the performance of overall water splitting. Experiments clarify the impressive role of the triphase hetero-interface of Rh, Cu3P, and MnP in interfacial electronic redistribution, which is significant for optimizing the catalyst's ability to adsorb and desorb reaction intermediates, thereby accelerating electrochemical reaction kinetics. Additionally, the rationally controlled multi-dimensional structure-comprising 0D Rh nanoparticles, 2D Cu3P/MnP nanosheets, and a 3D Ni substrate-endows the catalyst with a large electrochemically active surface area, excellent charge transfer ability, and abundant accessible active species. Therefore, the Rh/Cu3P/MnP catalyst demonstrates promising catalytic performance for the two key reactions in water splitting: the hydrogen evolution reaction and the oxygen evolution reaction. Moreover, a water electrolyzer utilizing Rh/Cu3P/MnP catalytic electrodes exhibits remarkable efficiency and remains stable over 50 h of continuous operation.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2025
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IF 9.7
Xi Wang,Fengyun Mao,Yun Gong
Prussian Blue Analogs (PBAs) stood out as promising candidates for sodium metal batteries cathode, leveraging their unique open-framework architecture, straightforward synthesis, and cost-effectiveness. However, PBAs were plagued by limited capacity arising from insufficient redox-active sites. Additionally, iodine cathode with high theoretical capacity (211 mAh g −1 ) suffer from poor practical performance due to the shuttle effect of polyiodides and slow kinetic conversion. The complex cathode to construct conversion reaction might be a better method to improve the capacity and easy to implement. Herein, we reported the design of a Cu-based PBAs/iodine composite cathode, where the PBAs framework serves as an iodine host and a conversion reaction mechanism via copper‑iodine coupling within PBAs cavities was established to enhance capacity. Various characterization results demonstrated that the Cu-based PBAs framework enabled favorable iodine encapsulation and facilitated Cu I coupling, enabling reversible conversion during charge/discharge progress. Density Functional Theory (DFT) simulations confirmed that the complexation of Cu-based PBAs with iodine represents a thermodynamically favorable process. Thereby, the assembled full battery achieved a high specific capacity of 276.4 mAh g −1 at 0.1 A g −1 and a capacity retention of 80.9 % after 1000 cycles at 0.3 A g −1 . This work introduced a novel Cu-based PBAs/iodine complexed conversion cathode, offering an innovative insight for the development of high-performance sodium metal batteries.
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MICROCHEMICAL JOURNAL
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2025
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IF 5.1
Luping Feng,Leikeqing Shen,Xueping Dang,Huaixia Chen
Copper 1,3,5-benzenetricarboxylate (Cu-BTC) holds promise for adsorption applications due to its high specific surface area, yet its aqueous instability severely restricts practical use. To overcome this limitation, a novel hydrophobic modification strategy using isopropyl alcohol (IPA) was developed to significantly enhance the structural stability of Cu-BTC in water. Capitalizing on this improved stability, the modified Cu-BTC-IPA was integrated with the conductive polymer 3,4-ethylenedioxythiophene (PEDOT) through electrodeposition copolymerization, creating a robust Cu-BTC-IPA@PEDOT composite coating for solid-phase microextraction (SPME). This developed coating enabled the establishment of a highly sensitive direct immersion SPME-GC-FID method for the efficient extraction and detection of six trace phenolic compounds. The resulting coating exhibited extraction capacities 2–8 times higher than the PEDOT and 6–40 times greater than the commercial PDMS coating. Adsorption mechanisms were elucidated through isotherm studies and electrostatic potential mapping. The established method exhibited low detection limits (0.01–0.08 μg L −1 ), a wide linear range (0.05–50 μg L −1 ), and was successfully applied to the analysis of five environmental water samples, yielding satisfactory recoveries ranging from 87.2 % to 117.9 %.
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Advanced Science
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2025
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IF 14.1
Siyao Cheng,Qinglin Zhou,Daohu Sheng,Wei Dong,Jinhu Dou,Yuanbiao Huang,Rong Cao,Aming Xie,Roland A. Fischer,Soumya Mukherjee,Weijin Li
Conduction and polarization are known to profoundly impact conductive metal–organic frameworks (c-MOFs) for their applications in electromagnetic wave (EMW) absorption. Albeit a few advances along c-MOF platforms in enhancing their EMW absorption performances, reticular modulation-led inter/intra-layer conduction and polarization loss remains an unmet challenge. To address this, a ligand substitution-guided bottom-up structural control strategy is introduced to study the depth of reticular modulation-led inter/intra-layer conduction and polarization loss in c-MOFs under an electromagnetic (EM) field. A family of triphenylene-X ligands (X = −NH 2 , −OH, and −SH) is harnessed to afford an isoreticular family of three Cu-based c-MOFs. Thanks to the distinct Cu─X bonds, such a platform allowed to systematically study the synergistic features of conduction and polarization loss in EMW absorption enhancement. One of the trio, Cu 3 (HITP) 2 (X = −NH 2 ; HITP, 2,3,6,7,10,11-hexahydroxytriphenylene) is identified with an optimal EM loss capacity under the EM field, achieving a record-high reflection loss of −63.03 dB in the effective absorption range of 3–18 GHz band. Setting up a new benchmark for EM loss among c-MOFs, this study introduces a way to leverage control in the charge mobility characteristics of Cu─X bonds relative to the dielectric losses at both molecular and atomic scales.
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ENERGY & FUELS
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2025
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IF 5.3
Chen Chen,Cengceng Du,Zhenyu Wang,Xin Chen,Yiming Wang,Na Ju,You Fu,Zilong Liu,Mingjie Jia,Shenyin Luo,Guangwen Xu,Junli Xu,Hong-bin Sun
The development of economical and efficient catalysts for the hydrogen evolution reaction (HER) is critical for achieving low-energy water splitting. This study demonstrates that self-supported Cu–Co–B/NF, synthesized via the one-pot NaBH4 reduction, is converted into the active species Cu–Co(OH)2 during the HER process. This in situ conversion was verified through XRD, HRTEM, XPS, and other characterization techniques. This noble-metal free catalyst exhibits exceptional HER performance. It requires overpotentials of only 32 mV and 148 mV to achieve the current densities of 10 mA cm–2 and 500 mA cm–2, respectively, and maintains stability for over 200 h at a current density of 200 mA cm–2. The density functional theory (DFT) calculations reveal that the Co(OH)2 holds the active site, while the introduction of copper optimizes both the hydrogen adsorption free energy (ΔGH*) and the d-band center, thereby enhancing the catalytic activity. More than water electrolysis, an Al–H2O battery employing Cu–Co–B/NF as the positive electrode achieves a high open-circuit voltage (1.29 V) and a maximum power density of 11.17 mW cm–2.
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Molecular Catalysis
·
2025
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IF 4.9
Pai Peng,Tianhao Li,Yichun Cai,Yao Zhang,Zhuoxi Li,Zhao-Bin Ding,Qiang Chen
Selective hydrogenation of nitroaromatics to anilines is a kind of important reaction in pharmacy industry and fine chemical engineering. However, this reaction is restrained by lack of catalysts and reaction system with high efficiency, energy saving, environmental protection and high selectivity. Herein, Cu nanoclusters were successfully encapsulated into Silicalite-1 zeolite by in-situ hydrothermal synthesis with ligand protection to obtain Cu@S-1 catalyst. The catalyst showed an excellent selectivity of 98 % with substrate conversion of 100 % in the hydrogenation of p -nitrostyrene to 4-vinylaniline using ammonia borane as hydrogen source, which was due to the preferential adsorption effect of Cu@S-1 catalyst on the nitro group. The Cu@S-1 catalyst also exhibits good recycling performance and substrate compatibility.
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Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 2
·121808
·
IF 7.5
Shuyan Miao,Jing Zhou,Zhen Xu,Yuting Wang,Rui Liu,Tian Gan
This work presents a disposable, integrated three-electrode sensor fabricated on paper via vacuum filtration of single-walled carbon nanotubes for rapid and sensitive detection of phthalylsulfacetamide (PSA) in environmental water. To improve performance, the working electrode was functionalized with a two-dimensional copper-based catalyst synthesized by one-pot pyrolysis, which provides high electrocatalytic activity. A molecularly imprinted polymer (MIP) layer was then constructed on the electrode surface through a dual-functional monomer strategy, generating specific recognition cavities complementary to PSA. The synergistic integration of the catalytic Cu-based material and the selective MIP enabled rapid, accurate, and sensitive PSA detection. Experimental results show a broad linear detection range (10 nM to 60 μM), a low detection limit (3.86 nM), good reproducibility (RSD of 3.9 %), good long-term stability (RSD of 1.5 % over 30 days), and high anti-interference performance against structural sulfonamide analogues and common environmental contaminants. When applied to spiked environmental water samples, the method achieved a recovery rate of 95.2–106 %, demonstrating its feasibility for on-site antibiotic residue detection.
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CHEMICAL ENGINEERING SCIENCE
·
2026
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IF 5.1
Ao Li,Luyao Sun,Suting Weng,Zhichen Liu,Qunhong Liu,Hongwei Zhang,Xiaojun Bao,Pei Yuan
Copper-based catalysts are widely studied for glycerol hydrogenolysis due to their high 1,2-propanediol (1,2-PDO) selectivity. However, their performance is fundamentally limited by the low hydrogenation activity of metal copper and the unbalanced distribution of acid-base sites. Herein, we designed a MgO-coordinated Cu x /Mg y -Al 2 O 3 catalyst through lattice-selective doping, where Mg 2+ incorporation generates interfacial Mg-O-Al acidic sites while surface MgO clusters provided tunable basicity. The optimized Cu 0.3 /Mg 0.1 -Al 2 O 3 catalyst achieves complete glycerol conversion with 94.2% 1,2-PDO selectivity at 250 °C/3.5 MPa H 2 , surpassing conventional Cu-based catalysts. Through In-situ diffuse reflectance infrared Fourier transformations spectroscopy (DRIFTS) analysis combined with CO 2 /NH 3 -TPD measurements reveal that Mg doping stabilizes metastable Cu + species and establishes an adjustable acid-base distribution, crucial for selective C O cleavage. Mechanistic analysis identifies a sequential dehydration-hydrogenation pathway, where the synergistic interaction between Cu + active centers and precisely tuned acid-base dual sites promotes intermediate transformation kinetics, and effectively suppresses undesired side reactions through spatial confinement effects. This work establishes a design principle for multifunctional catalysts in biomass upgrading.
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