Materials
·
2024
·Vol. 17
·期 11
·2543
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IF 3.1
Yuan Chen,Jiatong Yang,Aoxiong He,Jian Li,Weiliang Ma,Marie-Christine Record,Pascal Boulet,Juan Wang,Jan-Michael Albina
Due to the volume expansion effect during charge and discharge processes, the application of transition metal oxide anode materials in lithium-ion batteries is limited. Composite materials and carbon coating are often considered feasible improvement methods. In this study, three types of TiO2@Fe3O4@C microspheres with a core–double-shell structure, namely TFCS (TiO2@Fe3O4@C with 0.0119 g PVP), TFCM (TiO2@Fe3O4@C with 0.0238 g PVP), and TFCL (TiO2@Fe3O4@C with 0.0476 g PVP), were prepared using PVP (polyvinylpyrrolidone) as the carbon source through homogeneous precipitation and high-temperature carbonization methods. After 500 cycles at a current density of 2 C, the specific capacities of these three microspheres are all higher than that of TiO2@Fe2O3with significantly improved cycling stability. Among them, TFCM exhibits the highest specific capacity of 328.3 mAh·g−1, which was attributed to the amorphous carbon layer effectively mitigating the capacity decay caused by the volume expansion of iron oxide during charge and discharge processes. Additionally, the carbon coating layer enhances the electrical conductivity of the TiO2@Fe3O4@C materials, thereby improving their rate performance. Within the range of 100 to 1600 mA·g−1, the capacity retention rates for TiO2@Fe2O3, TFCS, TFCM, and TFCL are 27.2%, 35.2%, 35.9%, and 36.9%, respectively. This study provides insights into the development of new lithium-ion battery anode materials based on Ti and Fe oxides with the abundance and environmental friendliness of iron, titanium, and carbon resources in TiO2@Fe3O4@C microsphere anode materials, making this strategy potentially applicable.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Guanghao Li,Yujun Bao,Hui Zhang,Jingchun Wang,Xiaodan Wu,Rui Yan,Zhiqiang Wang,Yingxue Jin
Tumor metastasis and recurrence are closely related to immune escape and hypoxia. Chemodynamic therapy (CDT), photodynamic therapy (PDT), and photothermal therapy (PTT) can induce immunogenic cell death (ICD), and their combination with immune checkpoint agents is a promising therapeutic strategy. Iron based nanomaterials have received more and more attention, but their low Fenton reaction efficiency has hindered their clinical application. In this study, Fe 3 O 4 -carbon dots complex (Fe 3 O 4 -CDs) was synthesized, which was modified with ferrocenedicarboxylic acid by amide bond, and crosslinked into Fe 3 O 4 -CDs@Fc nano complex. The CDs catalyzed the Fenton reaction activity of Fe 3 O 4 by helping to improve the electron transfer efficiency, extended the reaction pH condition to 7.4. The Fe 3 O 4 -CDs@Fc exhibit exceptional optical activity, achieving a thermal conversion efficiency of 56.43 % under 808 nm light and a photosensitive single-line state oxygen quantum yield of 33 % under 660 nm light. Fe 3 O 4 -CDs@Fc improved intracellular oxygen level and inhibited hypoxia-inducing factor (HIF-1 α ) by in-situ oxygen production based on Fenton reaction. The multimodal combination of Fe 3 O 4 -CDs@Fc (CDT/PDT/PTT) strongly induced immune cell death (ICD). The expression of immune-related protein and HIF-1 α was investigated by immunofluorescence method. In vivo, Fe 3 O 4 -CDs@Fc combined with immune checkpoint blocker (antibody PD-L1, αPD-L1) effectively ablated primary tumors and inhibited distal tumor growth. Fe 3 O 4 -CDs@Fc is a promising immune-antitumor drug.
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ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Jing Zhang,Yang Xue,Lan Zhang,Jun Chen,Dayan Ma,Yingang Zhang,Yong Han
Bacterial infections seriously retard skin wound healing. To enhance the antibacterial efficiency and subsequent skin regeneration, a core–shell structured therapeutic platform, named FZAM, was designed with multiple antimicrobial pathways. FZAM consists of nanosized Fe3O4 as the core and ZIF-8 loaded with Au nanoparticles (NPs) and maltodextrin as the shell. Fe3O4 and Au NPs form a heterojunction that generates hyperthermia and abundant reactive oxide species (ROS) under near-infrared (NIR) irradiation. This heterojunction also exhibits outstanding peroxidase-like activity. When bacteria invade, maltodextrin plays a targeting effect to increase the interaction between FZAM and bacteria, and with the synergistic action of NIR-induced hyperthermia and ROS as well as Zn2+ from ZIF-8, FZAM kills more than 99% of bacteria at 200 μg mL–1. Fortunately, FZAM is cytocompatible and even promotes the biofunctions of fibroblasts and endothelial cells. In infected skin wound models, FZAM sterilizes bacteria with NIR irradiation and subsequently reduces the inflammatory response and accelerates skin regeneration. This work provides a core–shell structured therapy platform for treating infection with the assistance of NIR irradiation and helping skin wound healing.
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Journal of Water Process Engineering
·
2024
·
IF 6.3
Shiyuan Kang,Bing Yi,Xin Nie,Quan Wan,Hai Yang
Treatment of antibiotics-containing wastewater is imperative for ensuring environmental and public health. However, effectively removing antibiotics in environment is still a great challenge. Fabrication of sepiolite-supported iron oxide nanomaterials with large specific surface area and high reactivity is a promising solution for efficient antibiotics removal. In this work, a highly dispersed Fe 3 O 4 nanoparticle modified sepiolite composite (Fe 3 O 4 -sep-vacuum) was synthesized in-situ by employing a novel vacuum-filtration assisted coprecipitation strategy for the first time. Fe 3 O 4 -sep-vacuum exhibited the highest adsorption capacity to ciprofloxacin compared with those of pure Fe 3 O 4 nanoparticles, sepiolite, and those composites obtained by traditional coprecipitation methods. Approximately 93 % of CIP (20 mg/L) could be removed by Fe 3 O 4 -sep-vacuum within 20 min at initial pH 6.0. The kinetic and adsorption isotherms followed pseudo-second-order and Temkin models, respectively. The maximum adsorption capacity (q m ) of Fe 3 O 4 -sep-vacuum for CIP was 18.4 mg/g at initial pH 6.0. The solution pH, temperature, coexisting divalent cations, and HA concentration were demonstrated to play substantial roles in the adsorption processes of ciprofloxacin on Fe 3 O 4 -sep-vacuum surface. The Fe 3 O 4 -sep-vacuum maintained excellent stability and reusability during CIP adsorption process. Electrostatic interactions play a decisive role in the adsorption process of ciprofloxacin by Fe 3 O 4 -sep-vacuum. Hydrogen bonds and hydroxyl groups on the Fe 3 O 4 -sep-vacuum surface also play important roles in the adsorption process of ciprofloxacin. Fe 3 O 4 -sep-vacuum also exhibited excellent adsorption capacity to ofloxacin. These results indicate that the vacuum-filtration assisted coprecipitation strategy could be used to fabricate monodispersed nanoparticles modified sepiolite composites, which could be acted as promising materials for highly efficient remediating antibiotics contaminated wastewater.
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FOOD CHEMISTRY
·
2024
·
IF 8.5
Yu Su,Xinjie Yin,Xiaofeng Wei,Rui Xu,Liwen Wei,Yanhua Chen,Lan Ding,Daqian Song
A facile and efficient detection method is required to address the potential health risks of ketoprofen (KP) in animal-derived foods. Herein, we integrated molecularly imprinted polymers (MIPs) with Cu-doped Fe 3 O 4 nanozymes (Fe 3 O 4 –Cu) to develop a selective colorimetric sensor for KP detection. Chitosan and glutaraldehyde were used as functional monomers and cross-linkers to fabricate proposed the MIPs@Fe 3 O 4 –Cu. On KP addition, it was specifically captured by the imprinted cavities, thereby blocking the channels between chromogenic substrates and Fe 3 O 4 –Cu. Based on this rationale, a selective colorimetric sensor utilizing MIPs@Fe 3 O 4 –Cu was established, exhibiting a linear range of 0.25–100 μM and a detection limit of 0.073 μM. The developed method was validated through its application in milk samples, yielding satisfactory recoveries with low relative standard deviations. This efficient and selective colorimetric sensor holds immense significance for KP detection in complex samples.
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ANALYTICAL BIOCHEMISTRY
·
2024
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IF 2.6
Nanfei Yang,Yuncheng Bei,Yahong Huang,Wei Zheng,Jiehua Ma,Jiangqiong Ke
Serum Cystatin C (CysC) is an impressive marker for early diagnosis of renal dysfunction. In this work, we established a novel electrochemical immunosensor based on Fe 3 O 4 /AuNPs-MWCNTs@PDA nanocomposite for the detection of CysC. The Fe 3 O 4 /AuNPs-MWCNTs@PDA nanozyme complex by polydopamine encapsulation can not only carry massive detection antibodies, but also bind the electroactive substance toluidine blue (TB) through electrostatic adsorption. By immobilizing AuNPs onto the electrode to bind the capture antibody (Ab1), we constructed a sandwich electrochemical immunosensor with low cost, high sensitivity, and repeatability. The detection range is 3.9–125.0 ng/mL with a significant linear relationship between the current peak difference (ip) and logarithm of the CysC concentration. Moreover, the detection limit of the immunosensor is 0.157 ng/mL. We have successfully utilized this novel immunosensor to detect CysC in human serum samples, and these results have implications for its potential use in clinical application.
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LANGMUIR
·
2011
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IF 4.269
Bin Xu,Hongjing Dou,Ke Tao,Kang Sun,Jing Ding,Weibin Shi,Xiasheng Guo,Jiyu Li,Dong Zhang,Kun Sun
A new method for the fabrication of Fe3O4 nanoparticles enveloped by polymeric nanocapsules is proposed. This method is characterized by combining a double emulsification with the interfacial coprecipitation of iron salts to form Fe3O4/polymer composite nanocapsules in a single step. To demonstrate the viability of this approach, methoxy poly(ethylene glycol)-poly(lactide) (MePLEG) was chosen as the shell material for Fe3O4/MePLEG nanocapsules. In addition to the versatility offered for fabricating nanocapsules with different shell materials, the method was found to be convenient for adjusting the magnetite content of the nanocapsules from 0 to 43%. In addition to their confirmed T2-weighted magnetic resonance imaging (MRI) enhancement, the resultant composite nanocapsules display much more obvious acoustic responses than MePLEG nanocapsules in an acoustic investigation. Furthermore, the low toxicity of these composite nanocapsules, as confirmed by our study, combined with their magnetic and acoustic properties ensure that these composite nanocapsules have great potential in acting as ultrasonic/MRI dual contrast agents.
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JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
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2012
·
IF 2.947
Shaozhong Li,Wei Zhang,Man-Ho So,Chi-Ming Che,Runming Wang,Rong Chen
A facile solvothermal synthetic route has been successfully developed to fabricate Pd/Fe 3 O 4 nanocomposite with the assistance of polyvinylpyrrolidone (PVP) in N,N-dimethylformamide (DMF) solution. The as-prepared Pd/Fe 3 O 4 nanocomposite was composed of uniform 5 nm-sized Pd nanoparticles and Fe 3 O 4 nanocrystals with dimension of 40 nm. In this fabrication, PVP played an important role as a capping agent. The as-prepared Pd/Fe 3 O 4 nanocomposite exhibited superior catalytic performance and stability for various Suzuki coupling reactions, compared with single-component Pd nanoparticles under the same reaction conditions. More importantly, it displayed good magnetic property and could be easily separated from the reaction mixture by using a magnet and recycled for 10 times without losing its catalytic activity.
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FOOD CHEMISTRY
·
2011
·
IF 3.458
Huanshun Yin,Yunlei Zhou,Xiaomeng Meng,Tiantian Tang,Shiyun Ai,Lusheng Zhu
In this work, a simple and sensitive electrochemical method was developed to determine Sudan I based on magnetic Fe 3 O 4 nanoparticles modified glassy carbon electrode using cyclic voltammetry and differential pulse voltammetry. The sensor exhibited an obviously electrocatalytic activity towards the oxidation of Sudan I, which can be confirmed by the increased oxidation peak current and the decreased oxidation peak potential when compared with the bare GCE. The determination conditions, such as pH, modifier amount, accumulation time and accumulation potential, were optimised. And some kinetic parameters were calculated. Under the optimum experimental conditions, the oxidation current of Sudan I was proportional to its concentration from 0.01 to 1 μM and 1 to 20 μM. The detection limit was estimated to be 0.001 μM ( S / N = 3). The developed method was successfully applied to determine Sudan I content in food samples with satisfactory results.
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 3
·1-10
·
IF 5.3
Zou Ziwei,Chen Yi,Sun Rengang,Shi Boya,Jiang Li,Huang Feixiang
A surface plasmon resonance imaging (SPRi) biosensor is presented which facilitates rapid and sensitive detection of the ovarian cancer biomarker carbohydrate antigens 125 (CA125). The CA125 protein was specifically captured and directly recognized by polyadenylic (polyA)-modified DNA aptamer on the surface of a Au chip. The biosensor demonstrated a linear range of direct detection of CA125 based on SPRi from 20 nM to 0.5 nM, with a detection limit of 0.47 nM. Furthermore, Fe 3 O 4 nanoparticles were synthesized in situ on the carboxyl-functionalized two-dimensional (2D) material Ti 3 C 2 to obtain MXC/Fe 3 O 4 nanocomposites. The large surface area of Ti 3 C 2 provides ample binding sites for the in situ generation of Fe 3 O 4 and this facilitates subsequent immobilization of DNA aptamers. The amino-modified DNA aptamer interacted with carboxylate sites activated on the surface of Ti 3 C 2 , and the aptamer was immobilized on the MXC/Fe 3 O 4 nanocomposite surface. Due to the magnetic properties of Fe 3 O 4 nanoparticles within the composite material, CA125 protein in serum can be effectively captured and separated under an external magnetic field. The captured protein forms a sandwich amplification structure with the DNA adapter on the surface of the Au chip, thereby enhancing the detection signal of CA125. The biosensor demonstrates a linear detection range from 0.5 pM to 1000 pM, with a detection limit as low as 81 fM. The unique separation capability of the composite nanomaterials enables the biosensor to detect CA125 protein as low as 1 pM in complex liquid matrices such as serum, achieving exceptional selectivity, accuracy, and sensitivity in detecting the ovarian cancer marker. This capability significantly supports the early diagnosis of ovarian cancer. Graphical abstract
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ANALYTICA CHIMICA ACTA
·
2024
·
IF 5.7
Xiangyu Ma,Yaoying Cui,Kexing Zhu,Xiufang Zhu,Lijing Zhang,Liming Guo,Liangdong Feng,Jiadong Zhang,Yihong Wang,Ling Xia
Background Nanozymes , a new class of nanomaterials , have emerged as promising substitutes for enzymes in biosensor design due to their exceptional stability, affordability, and ready availability. While nanozymes address many limitations of natural enzymes, they still face challenges, particularly in achieving the catalytic activity levels of their natural counterparts. This indicates the need for enhancing the sensitivity of biosensors based on nanozymes. The catalytic activity of nanozyme can be significantly improved by regulating its size, morphology, and surface composition of nanomaterial. Results In this work, a kind of hollow core-shell structure was designed to enhance the catalytic activity of nanozymes. The hollow core-shell structure material consists of a nanozymes core layer, a hollow layer, and a MOF shell layer. Taking the classic peroxidase like Fe 3 O 4 as an example, the development of a novel nanozyme@MOF, specifically p-Fe 3 O 4 @PDA@ZIF-67, is detailed, showcasing its application in enhancing the sensitivity of sensors based on Fe 3 O 4 nanozymes. This innovative nanocomposite, featuring that MOF layer was designed to adsorb the signal molecules of the sensor to improve the utilization rate of reactive oxygen species generated by the nanozymes catalyzed reactions and the hollow layer was designed to prevent the active sites of nanozymes from being cover by the MOF layer. The manuscript emphasizes the nanocomposite's remarkable sensitivity in detecting hydrogen peroxide (H 2 O 2 ), coupled with high specificity and reproducibility, even in complex environments like milk samples. Significance and novelty This work firstly proposed and proved that Fe 3 O 4 nanozyme@MOF with hollow layer structure was designed to improve the catalytic activity of the Fe 3 O 4 nanozyme and the sensitivity of the sensors based on Fe 3 O 4 nanozyme. This research marks a significant advancement in nanozyme technology, demonstrating the potential of structural innovation in creating high-performance, sensitive, and stable biosensors for various applications.
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Nanomaterials
·
2024
·Vol. 14
·期 10
·852
·
IF 4.4
Jun Chen,Mengdong Tu,Mengying Xu,Depeng Gong,Xi Li,Chaocan Zhang
In this paper, we designed and investigated a reduction-based method to synthesize controllably monodisperse superparamagnetic nano Fe3O4colloidal clusters for magnetically responsive photonic crystals. It was shown that the addition of ascorbic acid (VC) to the system could synthesize monodisperse superparamagnetic nano Fe3O4and avoided the generation of γ-Fe2O3impurities, while the particle size and saturation magnetization intensity of nano Fe3O4gradually decreased with the increase of VC dosage. Nano Fe3O4could be rapidly assembled into photonic crystal dot matrix structures under a magnetic field, demonstrating tunability to various diffraction wavelengths. The nano Fe3O4modified by polyvinylpyrrolidone (PVP) and silicon coated could be stably dispersed in a variety of organic solvents and thus diffracted different wavelengths under a magnetic field. This is expected to be applied in various scenarios in the field of optical color development.
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