CERAMICS INTERNATIONAL
·
2026
·
IF 6
Zhigang Xu,Lei Xue,Zhongwei Liu,Kaiping He,Qiang Shen,Chuanbin Wang
This study systematically investigates the effects of varying Y 2 O 3 /ZrO 2 additive ratios on the phase evolution, microstructural characteristics, densification, mechanical properties, and tribological performance of β-Sialon ceramics fabricated via spark plasma sintering. The results demonstrate that both Y 2 O 3 and ZrO 2 promote the formation and densification of β-Sialon. Specifically, ZrO 2 facilitates the in-situ reaction with Si 3 N 4 and AlN to form ZrN, while Y 2 O 3 enhances the densification process through liquid phase formation. Notably, the content of in-situ formed ZrN decreases with the increase of Y 2 O 3 addition. Compared to the single addition of Y 2 O 3 , the optimized Y 2 O 3 /ZrO 2 ratio enables the formation of fine β-Sialon grains, well-dispersed ZrN particles, and minimal grain boundary phases. When 2 wt% Y 2 O 3 and 4 wt% ZrO 2 (SY2Z4) were added, the β-Sialon ceramic achieved an optimal balance of properties, where the Vickers hardness and fracture toughness reached 17.3 GPa and 6.7 MPa m 1/2 , respectively, representing increases of 27.2% and 28.9% compared to the sample with the sole addition of 6 wt% Y 2 O 3 (SY6). In terms of tribological properties, the SY2Z4 sample exhibits a significantly reduced coefficient of friction (0.582), wear volume loss (0.89 × 10 −2 mm 3 ), and wear rate (0.25 × 10 −5 mm 3 /(N·m)), which are 12.87%, 91.76%, and 91.67% lower than those of SY6, respectively. The results also indicate that abrasive wear is the dominant wear mode, and the in-situ formation of a protective tribofilm on the worn surface of SY2Z4 further contributes to its superior wear resistance. This work provides a feasible strategy for the microstructural regulation and performance optimization of β-Sialon ceramics via tailoring rare earth oxide/transition metal oxide additive systems, which holds great potential for extending their applications in high-wear-resistance engineering fields.
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高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2026
·
IF 4.9
Wei Xu,Jiaxiang Zang,Lu Zhou,Chuanlan Zhang,Liling Song,Dongyang Zhu,Xinfang Liu,Lihua Zhang
This study investigates the drug co-delivery, cytotoxicity and cell phagocytosis of the ternary compound of β-CD/CUR/MTX prepared via co-precipitation methods. Fourier-transform infrared spectroscopy (FTIR), powder X-ray diffraction (XRD), 1 H NMR and thermogravimetric analysis (TGA) confirmed the successful encapsulation of CUR and MTX. Scanning electron microscopy (SEM) revealed rock-like morphologies for β-CD, β-CD/MTX, and β-CD/CUR/MTX. While β-CD/CUR exhibited micro-scaled rod structures. Thermogravimetric analysis (TGA) indicated that the compound maintain stability up to 200°C, although the ternary β-CD/CUR/MTX demonstrated an initial mass loss at approximately 120°C. Molecular docking studies indicated a strong binding affinity of β-CD with both CUR and MTX driving by hydrogen bonding. DPPH radical scavenging assays demonstrated that the β-CD/CUR and β-CD/CUR/MTX exhibited enhanced water solubility and antioxidant capacities compared to β-CD and β-CD/MTX. In vitro release studies revealed β-CD/MTX displayed a controlled release behavior of MTX, achieving 80-95% within 120 minutes. Whereas CUR loaded β-CD/CUR compound exhibited a rapid release of approximately 50% within 20 minutes. The release profile of β-CD/CUR/MTX was significantly influenced by pH, in which the release at pH 5.3 was higher than that at pH 7.4, and exceeding 80% after 120 minutes. Importantly, the compounds (β-CD/CUR and β-CD/CUR/MTX) at a concentration of 80 μM had a significant inhibitory cell viability and phagocytosed behavior on HepG2.
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高影响因子
Food Chemistry-X
·
2026
·
IF 9.2
Lihua Zhang,Zhenwei Li,Siqi Yu,Guanchen Wu,Jiawei Xue,Lala Li,Wei Xu
KGM addition decreases droplet size and improves uniformity in CAS-based emulsions. • CRG addition transformed the emulsion into gel, improving the system's stability. • The emulsion gel has excellent textural properties and water-holding capacity. • The emulsion gel improved β-carotene storage stability and photostability. This study investigated the effect of κ-carrageenan (CRG) concentration on konjac glucomannan (KGM)/sodium caseinate-based emulsion gels and evaluated their protective effect on β-carotene. Adding CRG induced a sol-gel transition, resulting in structured emulsion gels. Microstructural analysis showed that the synergistic interaction between CRG and KGM facilitated the formation of a denser and more stable gel network, within which oil droplets were uniformly distributed. These structural enhancements enhanced the rheological and textural properties of the gel and increased its water-holding capacity to 98.1%. Furthermore, the gels effectively protected β-carotene during storage and ultraviolet exposure. At 1.5% CRG, 62% of the β-carotene was retained after 15 days of storage, indicating reduced oxidative degradation. Notably, 1.0% CRG provided superior photoprotection, with more than 50% of the β-carotene retained after 8 h of ultraviolet irradiation. Overall, these findings highlight the potential of KGM/CRG emulsion gels as a delivery system for lipophilic nutrients.
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NUTRITIONAL NEUROSCIENCE
·
2026
·
IF 3.1
Dawei Xu,Luge Chen,Xiaohu Chen,Weiming Jiang,Lijuan Sun
Background and Objectives Insomnia is a major public health issue that impairs daily functions and quality of life. Sleep-onset difficulty, a common complaint among patients, is accompanied by reduced central serotonin (5-HT) function. β-myrcene from lavender has sedative–hypnotic effects via serotonergic pathways, but most previous studies used intraperitoneal injection, which causes stress and limits clinical translation. Here, we asked whether non-invasive inhalation of β-myrcene produced similar effects in a mouse model of insomnia with low 5-HT function, and explored the underlying mechanisms.Methods β-myrcene was given to PCPA-induced insomnia mice by inhalation (with intraperitoneal injection as a pharmacodynamic control). In the inhalation group, sleep and behavior were evaluated using the amobarbital sodium sleep test and spontaneous locomotor activity test. ELISA, RT-qPCR, Western blot, and 16S rRNA sequencing were applied to study mechanisms.Results Inhaled β-myrcene shortened sleep latency and prolonged sleep duration. It also reduced oxidative stress and modulated GABA, 5-HT, and glutamate levels. These changes were accompanied by upregulation of mRNAs such as GABAARγ2 and 5-HT1A, as well as proteins including GAD65/67 and PKA, suggesting involvement of 5-HT1A/PKA signaling. Additionally, inhalation of β-myrcene was correlated with alterations in gut microbiota composition in PCPA-induced insomnia mice.Conclusions Our findings indicate that inhaled β-myrcene is associated with sedative–hypnotic effects and alterations in gut microbiota composition in PCPA-induced insomnia mice, potentially involving modulation of 5-HT1A/PKA signaling.
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高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Jialing Long,Jin Liu,Bowen Qin,Rui Shi,Mingming Zheng,Yibin Zhou,Shiyi Li
Binary oleogels were developed using β-sitosterol (Sit) and propyl gallate (PG). • The 5:5 M ratio (Sit:PG) showed the densest and most ordered crystal network. • Hydrogen bonding between Sit and PG drove the self-assembly of oleogels. • The oleogels showed excellent thermal and freeze-thaw stability. In this study, binary oleogels based on β-sitosterol (Sit) and natural phenolics bearing aromatic hydroxyl groups were developed. Among five screened phenolics (eugenol, propyl gallate (PG), thymol, carvacrol, and resveratrol), only PG formed stable binary oleogels with Sit, specifically at Sit:PG molar ratios ranging from 2:8 to 6:4. All resulting Sit-PG binary oleogels exhibited short needle-like crystals, with hydrogen bonding identified as the primary molecular interaction driving self-assembly. Among these, the 5:5 M ratio (S5P5) showed the highest fractal dimension (D b = 1.7672), the smallest intermolecular spacing and subcell dimensions, and the strongest gel network. Consequently, this formulation also showed the highest storage modulus (7.71 × 10 5 Pa), viscosity, and thixotropic recovery rate (49.47%), along with excellent oil binding capacity (98.21%) and hardness (8.62 N). These findings identify PG as an effective co-gelator for Sit and provide insights into the design of binary oleogels. Download: Download high-res image (231KB) Download: Download full-size image
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
·
IF 8.7
Deyi Peng,Wenchang Zhang,Chengfeng Tan,Xia Zhang,Yan Zhao,Yide Han,Mi Wu
β-Chitin nanofibers enable freeze–thaw reinforcement of hemostatic cryogels. • Freeze–thaw cycling improves structural integrity and rapid blood absorption. • β-Chitin nanofibers mainly enhance coagulation through the intrinsic pathway. • The sponges show low hemolysis and high cytocompatibility in vitro. • An optimized sponge achieves 3.5 s hemostasis in a rat liver injury model. Non-compressible hemorrhage remains a major clinical challenge, requiring hemostatic materials with rapid blood absorption and sufficient mechanical robustness. Conventional carboxymethyl chitosan (CMCS)/sodium alginate (SA) polyelectrolyte complex (PEC) sponges exhibit high swelling capacity but limited uptake kinetics and mechanical strength. Here, β-chitin nanofibers (β-ChNFs) were incorporated into the CMCS/SA system to establish a freeze–thaw reinforcement strategy depended on β-ChNFs. Repeated freeze–thaw cycles had little effect on the storage modulus (G′) of CMCS/SA alone, whereas G′ progressively increased with the number of cycles in β-ChNF-containing systems. After six freeze–thaw cycles and electrostatic complexation, the resulting double-network sponges featured layered, stacked pore walls that conferred excellent shape recovery and fatigue resistance, together with rapid blood absorption and enhanced platelet–red blood cell adhesion, thereby accelerating blood clotting. The β-ChNF-dependent procoagulant enhancement was mainly associated with activation of the intrinsic coagulation pathway, and the sponges also exhibited favorable hemocompatibility and cytocompatibility. In a rat liver perforation model, the optimized sponge demonstrated significantly superior hemostatic performance compared with a commercial gelatin sponge, achieving a hemostasis time of 3.5 s and blood loss of 80 mg, underscoring its strong potential for controlling non-compressible hemorrhage. Download: Download high-res image (144KB) Download: Download full-size image
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高影响因子
PHYTOMEDICINE
·
2026
·
IF 11.3
Ningyue Liu,Xuan Li,Xiaojuan Xu
Lentinus β-glucan (LBG) could directly interact with the human colon cancer cells. • PRSS3 was identified as the potential target of LBG. • LBG inhibits colon cancer cell proliferation and promotes apoptosis by targeting PRSS3. Lentinus β-glucan (LBG), an edible dietary fiber, has promising anticancer potential. However, the anticancer mechanism remains poorly understood. Herein, we focus on the anti-colon cancer mechanism of four LBGs with different molecular weights. As a result, LBGs could directly interact with the human colon cancer cells and were even ingested into cells. Mass spectrometry results reveal that the protein interacting with LBGs was most likely PRSS3. Molecular docking simulation further confirmed LBGs interacted with PRSS3 through hydrogen bonding, van der Waals forces, and hydrophobic interactions. In vitro results demonstrate that LBGs down-regulated PRSS3 expression in colon carcinoma cells, as well as decreased cell viability. Meanwhile, in vivo studies reveal that LBGs targeted the carcinogenic promoter of PRSS3, leading to cancer cell proliferation inhibition and apoptosis promotion. This study provides new insights that LBG can be used for clinical colon cancer treatment as a PRSS3 inhibitor without system toxicity. Download: Download high-res image (245KB) Download: Download full-size image
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PubMed
高影响因子
Foods
·
2026
·Vol. 15
·期 17
·2957
·
IF 6
Cuixia Yang,Penghui Wei,Zhaotong Duan,Tinghui Duan,Mina Nan,Huali Xue,Yang Bi,Yan Yin
Postharvest spoilage of fresh fruits demands efficient bio-based packaging films. Here, chitosan/gelatin (CG) films were incorporated with β-cyclodextrin-encapsulated clove essential oil microcapsules (β-CD@CEO MCs) at varying loadings. The results suggested that CEO encapsulation occurred within β-CD cavities and hydrogen-bond binding of MCs to the CG matrix. At 0.4% MCs, the composite film showed 60.11% higher tensile strength, excellent UV shielding, lower water vapor transmission rate, and strong antioxidant activity (DPPH 89.6%, ABTS 97.1), along with 58.21% biodegradation after 16 days of soil burial. In vitro release studies revealed a pH-responsive sustained release profile of CEO from the composite films, with faster release under acidic conditions (98.5% at pH 3.5 after 72 h) compared to neutral conditions (87.2% at pH 7.0), indicating the potential for targeted release on the weakly acidic grape surface. The film also exhibited significant antimicrobial effects againstBotrytis cinerea,Penicillium gladioli,Staphylococcus aureus, andEscherichia coli. In table grape preservation, CG/MCs-0.4 film effectively delayed decay, reduced weight loss by 38.79%, maintained firmness and color, and preserved higher levels of soluble solids, titratable acidity, reducing sugars, and vitamin C compared to polyethylene packaging and untreated controls.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Lu Li,Xinyan Chen,Yuxuan Zhang,Luqiao Tian,Chaoran Lei,Miao Lin,Juan Wei,Dejian Huang,Yongquan Xu,Guiqiang Fei
A Rhodamine 6G fluorescence sensor was developed through synergistic enhancement combining β-cyclodextrin host–guest regulation with hollow-sphere photonic crystals amplification. • The sensor enabled ultrasensitive detection of (-)-epigallocatechin gallate with an ultra-low theoretical detection limit of 5.1 × 10 -16 mol·L -1 and a broad concentration-dependent fluorescence response • The sensing platform exhibited excellent reproducibility and strong anti-interference capability, demonstrating reliable performance in complex sample matrices. (−)-Epigallocatechin gallate (EGCG) is one of the most abundant bioactive polyphenols in tea, and its rapid and sensitive determination is of great importance for food quality control and safety evaluation. Herein, a highly sensitive fluorescence sensing platform based on the synergistic enhancement of hollow-sphere photonic crystals (HSPCs) and β-cyclodextrin (β-CD) is developed for the quantitative detection of EGCG. The photonic band-edge effect and light localization effect of HSPCs, combined with microenvironment regulation induced by the host–guest inclusion interaction of β-CD, synergistically amplify the fluorescence emission intensity of rhodamine 6G (Rh6G). Under acidic conditions, EGCG reacts with ammonium molybdate to form molybdate ester complexes, which induce selective fluorescence quenching of Rh6G, enabling an indirect sensing strategy with a good linear response. Benefiting from the synergistic contribution of structural optical field modulation and molecular microenvironment engineering, the proposed sensor achieves a theoretical limit of detection (LOD) of 5.1 × 10 −16 mol·L −1 , together with good selectivity, anti-interference capability, and reusability. In practical tea sample analysis, satisfactory recoveries are obtained, confirming the accuracy and reliability of the method. This study demonstrates that synergistic fluorescence amplification provides an effective strategy for the sensitive detection of bioactive small molecules in complex food matrices. Download: Download high-res image (139KB) Download: Download full-size image
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高影响因子
Chemistry-An Asian Journal
·
2026
·Vol. 21
·期 7
·e70731
·
IF 3.2
Xiaoyu Meng,Xuan Shi,Kunlin Chen
Rising demand for textiles combining odor control, antibacterial properties, and ultraviolet (UV) protection has stimulated interest in durable functional finishing approaches. Microcapsules were prepared using 5-propylhydantoin (PHDT) and menthol essential oil as dual cores, encapsulated within a polyurethane shell incorporating 2-(4-bromophenyl)-5-phenylthiophene-modified β-cyclodextrin (β-CD). The microcapsules were further applied to fabric, and the adsorption and degradation behaviors toward trans-2-nonenal were investigated. The dual-core system, together with the photocatalytic activity of the modified β-CD, significantly improved odor removal efficiency. Further analysis of the individual and combined contributions of PHDT and the thiophene-based component revealed a pronounced synergistic effect, leading to improved adsorption and degradation performance on the treated fabrics. In addition, the functional cotton fabric exhibited strong antibacterial activity, achieving inhibition efficiencies of 97% against Escherichia coli and 92% against Staphylococcus aureus . The integration of modified β-CD also substantially improved UV protection, increasing the ultraviolet protection factor (UPF) to 71, while maintaining a value of approximately 40 after 30 abrasion cycles. This study presents a feasible pathway for developing multifunctional textile materials with durable odor management and protective performance.
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PubMed
高影响因子
Coatings
·
2026
·Vol. 16
·期 4
·498
·
IF 3.4
Mengzi Wang,Xinyu Tan,Lei Jin,Guiguang Qi,Weiwei Hu,Shengyu Chen,Silu Li,Yulong Qiao,Xiaobo Chen,Shengchao Qiu
The inefficient utilization of industrial by-product phosphogypsum, coupled with the increasing global demand for cooling, has spurred the development of sustainable radiative cooling materials. Compared with conventional cooling coatings that primarily rely on expensive synthetic materials or complex fabrication processes, this study provides a promising cost-effective and sustainable route for integrating industrial solid waste valorization with zero-energy cooling technologies. In this study, we fabricated a composite coating (β-HPG@CA/SiO2@OTS) consisting of β-hemihydrate phosphogypsum (β-HPG), a derivative product of phosphogypsum, cellulose acetate (CA), SiO2particles and octadecyltrichlorosilane (OTS) by a facile combination of blade coating and spraying, which exhibited strong solar reflectivity (90.9%), high mid-infrared emissivity (98.7%) and satisfactory superhydrophobicity (157°). The as-prepared composite achieved an ambient temperature drop of 18.7 °C under direct sunlight during sunny weather, achieving a net cooling power of 92.23 W/m2. Meanwhile, the composite coating exhibits excellent durability after prolonged immersion in strongly acidic and alkaline solutions, ultraviolet radiation and outdoor testing. Owing to its simple fabrication process and robust cooling performance, this coating shows promise for scalable production and practical outdoor applications, such as building envelopes and equipment enclosures.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Yongseok Jeong,Jeongwoo Han,Sooyoung Lee,Gyeongsoo Kim,Dabin Kim,Jonggeun Sung,Changsik Song
Covalent adaptable networks (CANs) have emerged as promising alternatives to conventional polymer matrices to address the limited service life of carbon fiber-reinforced polymers (CFRPs); however, their mechanical and thermal performance is typically inferior. In this study, we synthesized a CAN matrix by introducing divinyl sulfone (DVS) into an epoxy network, achieving an unusual combination of high performance and malleability. The rigid network of the epoxy resin and the strong polarity of DVS yielded a β -amino sulfone-based CAN-based CFRP (BAS-CP) with an exceptionally high glass transition temperature (170.9 °C) and a tensile strength (876.9 MPa). In addition, the dynamic bond exchange enables crack self-healing, potential fabrication of enduring prepregs, and reshaping of fully cured CFRPs. β -Amino sulfone-based CAN (BAS) can be readily degraded using a mild oxidizing agent such as H 2 O 2 , enabling efficient recovery of carbon fibers from BAS-CP. The combination of these properties, low-cost monomers, and the simplicity of BAS synthesis suggest a new pathway for the development of cost-efficient, sustainable, and high-performance CFRPs.
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高影响因子
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