ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Dangge Gao,Fangxing Wang,Chi Zheng,Bin Lv,Jianzhong Ma
Cotton textiles with persistent antibacterial qualities are crucial in halting the spread of bacteria and other infections. However, fugitive bacteria and drug-resistant pathogens have rendered tremendous challenges in the development of cotton fabrics with long-lasting antibacterial efficacy. The work aimed to innovatively propose a functional cotton fabric integrating intelligent bacteria-capturing and dual antibacterial properties for efficacious personal health management. The functional cotton fabric was created by modifying the surface of cotton fabric with the quaternized carboxymethyl chitosan (Q-CF) and then covalently grafting the silver@Zr-based porphyrin metal–organic skeleton (Ag@MOF-545) prepared via the “bottle-around-the-boat” method on the surface of Q-CF (AM/Q-CF). In this process, the functional cotton fabric could capture bacteria via positive charges on the surface of the quaternized carboxymethyl chitosan. Due to the synergistic effect of broad-spectrum antibacterial silver nanoparticles (AgNPs) and the visible light-driven antibacterial Zr-based porphyrin metal–organic skeleton (MOF-545), the metabolism of bacteria and drug-resistant strains was well inhibited, which endowed the AM/Q-CF with lasting dual antibacterial properties. After repeated laundering cycles, abrasion cycles, simulated sweat soaking, and long-term storage, the antibacterial rates of AM/Q-CF were over 85%. Altogether, the results provided a potential antibiotic-free alternative for the preparation of durable antibacterial cotton fabrics.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nano Research
·
2024
·Vol. 17
·期 7
·5863-5871
·
IF 9.5
Ke Yanjing,Zhang Jiaxing,Peng Xin,Zhang Zhiyi,Wang Xu,Qi Wei,Wang Mengfan
Recently, many efforts have been dedicated to construct artificial catalysts with enzyme-like activity. However, it is still a big challenge to endow artificial catalysts with specific substrate selectivity. In this study, we developed a facile strategy to construct a MIL-53(Fe)-based nanocatalyst with designable selectivity in the degradation of oxytetracycline (OTC). Through the Fe–O–P conjunction, oxytetracycline aptamer (OA) can be easily anchored on MIL-53(Fe) to provide the specific site for OTC binding. We verified that the obtained MIL-53(Fe)-Apt nanocatalyst displayed enhanced catalytic ability in the degradation of OTC, whereas obvious suppression toward other substrate analogues. This performance therefore brings about an anticipated selectivity toward OTC. Moreover, we highlighted that the configuration of aptamers on MIL-53(Fe) can be modulated through varying conjunction mode. Structure–function analysis revealed that aptamer configuration affects the local concentration of substrate around catalytic site, which thus decides the catalytic performance toward OTC. This work presented a facile and promising strategy for developing artificial catalysts with designable selectivity.
✓ 已验证
产品关联
DOI
高影响因子
Molecular Catalysis
·
2024
·
IF 3.9
Yifei Chen,Xinnan Zhao,Chen Xin,Xiuqin Dong,Hao Gong
This work explored the role of defective sites on the hydroformylation of n-butene through ligand regulation. The investigation examined the effect of modulator properties on defect sites and rhodium loading, and optimized the H 2 BDC/modulator ratio to improve catalyst activity. Atomically dispersed Rh is anchored to these highly dispersed defect sites, effectively preventing aggregation and thereby enhancing hydrogenation ability. Under optimal conditions, the catalyst achieved a conversion of 96.9 %, with an overall aldehyde selectivity of 90 %. DRIFTS analysis provided compelling evidence that Rh(CO) 2 and HRhCO species were formed on 1Rh/MOF-5-HBC, improving CO insertion capability. This study highlights the significance of MOFs as catalyst supports in enhancing performance through defect engineering. The ability of the modulator to induce defect formation was measured by p K a. Meanwhile, it has been discovered that the length differences between the modulator and the MOF organic ligand can have a significant impact on the stability of defective MOFs.
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2024
·
IF 5.6
Yi Xiao,Pengcheng Huang,Fang-Ying Wu
α-Glucosidase, which directly involves in the metabolism of starch and glycogen and causes an increase in blood sugar level, is the major target enzyme for the precaution and therapy of type II diabetes. Based on the previous work, we adopted a post-synthetic modification method to encapsulate Tb 3+ into Ce-MOF nanozyme which owned mixed valence states. Tb@Ce-MOF displayed induced luminescence characteristic and exceptional oxidase-like activity that could oxidize colorless 3,3′,5,5′-tetramethylbenzidine (TMB) to blue ox-TMB. α-Glucosidase can hydrolyze the substrate l -ascorbic acid-2- O -α- d -glucopyranosyl (AAG) to generate ascorbic acid (AA), which could increase the Ce 3+ /Ce 4+ redox valence mode in Tb@Ce-MOF, leading to the inhibition of the allochroic reaction of TMB and the decreased absorption of ox-TMB at 652 nm. The energy transfer (EnT) process from Ce 3+ to Tb 3+ will enhance due to the increased Ce 3+ /Ce 4+ mode in Tb@Ce-MOF, which will result in an enhanced fluorescence signal of Tb@Ce-MOF at 550 nm. But the addition of inhibitor acarbose will inhibit the above process. We have constructed a dual-mode detection platform of α-glucosidase and its inhibitor via colorimetric and fluorometric method. The linear range of α-glucosidase were 0.01–0.5 U/mL (colorimetric mode) and 0.8–1.5 U/mL (fluorometric mode), respectively, with a detection limit as low as 0.0018 U/mL. Furthermore, our approach was also successfully employed to the analysis of α-glucosidase in serum samples.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Liling Wang,Yanbin Wang,Yifeng Zhou
Bimetallic MOF derivatives have shown excellent performance as nano-enzymes in the field of catalysis. Herein, PdCo oxide nanoflowers with three-dimensional flower were prepared by a simple pyrolysis method on a precursor of bimetallic PdCo-MOF. PdCoO x showed excellent peroxidase mimic activity, which could significantly promote the oxidation of TMB by H 2 O 2 . Compared with CoO x , the peroxidase mimic activity of the optimized PdCoO x -300 increased by 2.41-fold. PdCoO x -300 has high affinity for TMB and H 2 O 2 with K m values of 0.16 mM and 2.11 mM, which are only 57.03% and 36.87% of HRP, respectively. The highly specific peroxidase mimic activity is conducive to the sensitive detection of H 2 O 2 , glucose and ascorbic acid with limit of detection of 10, 100 and 10 nM, respectively. Furthermore, the total antioxidant capacity in the actual beverage samples was conducted, which showed good anti-interference ability and recovery rate.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Advanced Healthcare Materials
·
2025
·
IF 9.6
Lu Liu,Daiyong Chao,Qing Dong,Xianli Zhang,Kai Zhang,Zhenyu Ju
Doxorubicin (DOX), a potent anthracycline chemotherapeutic agent, is widely used in cancer treatment but is associated with significant adverse effects, particularly DOX-induced cardiomyopathy (DIC). DIC pathogenesis involves the generation of reactive oxygen species (ROS) and ferroptosis induction. Novel therapeutic strategies targeting antioxidant defenses and ferroptosis inhibition are essential for mitigating DIC. An innovative bimetallic metal-organic framework (MOF), NiCu-MOF (NCM), is developed, exhibiting multifaceted antioxidant enzyme-mimicking activities that effectively scavenge a broad spectrum of ROS. Additionally, the bimetallic NCM exhibits excellent iron-chelating ability. In vitro experiments demonstrate that NCM significantly reduces cardiomyocyte death by attenuating ROS levels and inhibiting ferroptosis. Furthermore, in a mouse model of DIC, NCM treatment results in substantial myocardial protection, evidenced by improved cardiac function and structural integrity. This protective effect is attributed to suppression of ferroptosis, preservation of mitochondrial function, and attenuation of inflammatory responses. Collectively, these findings highlight biocompatible NCM's potential as a novel cardioprotective agent and offer a promising therapeutic strategy for managing DIC.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
DALTON TRANSACTIONS
·
2024
·Vol. 53
·期 31
·12936-12942
·
IF 3.5
Jiaqi He,Xin Deng,Wenting Sun,Wenjing Shang,Yongbing Lou,Jinxi Chen
To address the shortage of fossil energy, the development of affordable and efficient non-precious metal catalysts for oxygen evolution reaction (OER) from electrocatalytic water splitting is still a crucial challenge. Herein, the bimetallic NiFe metal–organic frameworks (MOFs) are synthesized by hydrothermal and electro-deposition. Benefiting from the synergistic effect of Fe and Ni, the catalyst demonstrates extraordinary activity, which exhibits favorable OER catalytic activity in 1 M KOH solution with an overpotential of 206 mV at 10 mA cm−2. Meanwhile, the obtained NiFe-NDC presents promising stability in the 20 h test at 50 mA cm−2.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHINESE CHEMICAL LETTERS
·
2024
·
IF 9.4
Yan-Kai Zhang,Yong-Zheng Zhang,Chun-Xiao Jia,Fang Wang,Xiuling Zhang,Yuhang Wu,Zhongmin Liu,Hui Hu,Da-Shuai Zhang,Longlong Geng,Jing Xu,Hongliang Huang
ABSTRACT The highly desired goal is to employ visible light for the photocatalytic reduction of toxic Cr(VI) to environmentally friendly Cr(III). Metal-organic frameworks (MOFs) are considered one of the most promising materials for the photoreduction of Cr(VI). Nevertheless, developing MOFs with high stability and activity is still challenging. Herein, we report a stable Zn-based MOF (named DZU-64 ) with an anthracene functionalized ligand, and its reduction of Cr(VI) under sunlight irradiation was investigated. DZU-64 exhibits excellent chemical stability in pH range of 2−14 aqueous solution, and remarkable thermal stability to 570°C. For the photoreduction of Cr(VI) under visible light irradiation, DZU-64 gives a record rate constant of 0.467 min −1 and a high Cr(VI) reduction rate of 6.68 mg Cr (VI) g −1 cata min −1 at pH 2. Moreover, under real solar light, DZU-64 can also efficiently reduce Cr(VI) to Cr(III) while retaining its catalytic activity throughout 5 cycles without any notable decline, further demonstrating its great application prospect. By combining the photovoltaic performance tests and electron spin resonance test, the possible photoreduction of Cr(VI) mechanism in DZU-64 was analyzed.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Zhi Luo,Jing Li,Shenglan Hu,Lingling Zheng,Lixin Xu,Biyang Deng
In this study, Ru(bpy) 3 2+ and oxalate (C 2 O 4 2− ) in Ru@Zn-MOF generated self-enhanced electrochemiluminescence (ECL). The self-enhanced ECL composite exhibited a short electron transfer distance and minimal energy loss, which ensured the high and stable luminescence efficiency of Ru@Zn-MOF. A MnO 2 @AuNPs nanocomposite was introduced into Ru@Zn-MOF via antigen–antibody interactions in the presence of squamous cell carcinoma antigen (SCCA). This significantly quenched the ECL signal due to the combined effect of the dual quenchers, MnO 2 NFs and AuNPs. A highly efficient ECL-RET immunosensor was constructed for the sensitive detection of SCCA in the linear range of 1 fg/mL to 100 ng/mL, with a limit of detection of 0.26 fg/mL (S/N = 3). This immunosensor has broad clinical applications for the quantitative detection of biomarkers.
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Jingling Gong,Ruirui Jin,Bin Xiang,Fuli Du,Weimin Liu,Jian Li
Membrane technology has become one of the most effective methods for treating oily wastewater, which is harmful to the survival of ecosystems. However, separation membranes often suffer from serious fouling problems. Therefore, in this work, MOF-303 nanoparticles and attapulgites (APT) were loaded on the surface of polyvinylidene fluoride (PVDF) membrane based on the layer-by-layer self-assembly to construct MOF/APT/PEG composite membrane with excellent superhydrophilicity/underwater superoleophobicity, anti-fouling ability and outstanding emulsion separation performance, durability. It should be noted that a unique “absorption-storage” strategy for water molecules has been creatively adopted to realize anti-fouling and promote permeability. The separation efficiency of MOF/APT/PEG composite membrane was as high as 99.6 %, and permeability was above 1316 LMH/bar. Particularly, separation performance still remained stable after 10 cycles and 60 min of cross-flow separation. This study introduces a comprehensive and straightforward methodology for the development of membranes with anti-fouling properties aimed at the highly efficient treatment of oily wastewater.
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Bo Liu,Liangliang Xiong,Xiaoqiang Fan
In this work, two-dimensional UiO-67 nanosheets are successfully modified on graphene oxide (GO). The synthesized GO@2D-UiO-67 composite not only exhibits the electrical insulation characteristics of Zr-MOF, but also leverages the passive barrier effect of its 2D layered structure to prepare a highly anticorrosive epoxy coating. Electrochemical measurements reveal that the impedance modulus of the GO@UiO-67/EP composite coating remain two orders of magnitude higher than that of the pure EP coating even after 28 days of immersion in 3.5 wt% NaCl solution. This good long-term anti-corrosion performance could derive from the enhanced crosslinking density of composite coating due to the incorporation of GO@UiO-67 nanosheets. Furthermore, the shielding effect of layered structure and the corrosion inhibition behavior of organic ligands are proved to improve the corrosion resistance properties of composite coating. This research fills the application void of two-dimensional Zr-MOF composites in resin coatings, as well as serves as a forward-looking initiative to enhance the long-term corrosion protection of epoxy resin coatings.
✓ 已验证
产品关联
DOI
高影响因子
Analytical Methods
·
2024
·
IF 2.7
Wenxia Xue,Jihong Fu,Yaxue Zhang,Shuxian Ren,Guoqi Liu
Surface-enhanced Raman scattering (SERS) enables pesticide residue monitoring to become facile and efficient. In this study, a core–shell structured gold nanoparticles@ZnCo metal–organic framework (AuNPs@ZnCo-MOF) SERS substrate was designed and successfully synthesized for efficient and selective detection of thiram. The bimetallic ZnCo-MOF shell can not only enrich the targeted molecules in the electromagnetic field because of its excellent absorptive capacity, but also act as a stabilized matrix for protecting the AuNPs from aggregation. The AuNPs@ZnCo-MOFs exhibited a high enhancement factor (EF) of 3.51 × 106 and a low detection limit of 1 × 10−7 mol L−1. Besides, the substrate material showed exceptional stability for up to 28 days at room temperature. The AuNPs@ZnCo-MOFs were used to detect thiram which displayed wide linearity (1 × 10−7 to 1 × 10−4 mol L−1) and high recoveries (83.45–99.61%). Moreover, the AuNPs@ZnCo-MOF SERS substrate exhibited excellent anti-interference ability and size selectivity for the target molecules. These indicate that the AuNPs@ZnCo-MOF substrate has great potential for the detection of thiram residues in practical applications.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）