CHEMICAL PAPERS
·
2023
·Vol. 77
·期 7
·3671-3678
·
IF 2.2
Zhou Qi,Zhou Ting,Tu Yifeng,Yan Jilin
Tyrosinase is an enzyme in the process of melanin formation and relates to the occurrence of freckles, brown spots, or excessive deposition of melanin in human body and other diseases. In this work, a turn-on fluorescence detection toward tyrosinase was developed. Manganese dioxide nanosheets were conveniently synthesized as an oxidizing agent. These nanosheets converted non-fluorescent o-phenylenediamine (OPD) into a fluorescent product. This reaction and the related fluorescence could be inhibited by reductive dopamine. When tyrosinase was introduced, it catalyzed the oxidation of dopamine and thus led to a recovery of the fluorescence. This signaling provided enhanced fluorescence responses toward tyrosinase in the range 0.006–0.08 U/mL, with a detection limit at 0.003 U/mL. The scheme was successfully applied onto practical samples. Graphical abstract
✓ 已验证
产品关联
DOI
高影响因子
IONICS
·
2023
·Vol. 29
·期 4
·1459-1468
·
IF 2.8
Yang Shuo,Xue Kui,Li Chen,Wang Hongbin,Shi Shaojun,Zhou Liujiang,Zhang Yongqi
The severe dendrite growth on Zn anode during the platting process is still a serious roadblock to the commercialization of rechargeable aqueous Zn-based energy storage devices. Introducing electrolyte additives is a facile and efficient strategy to suppress the formation of dendrites. In this work, we found that Na + cations can inhibit the growth of dendrites via the shielding effect during the Zn platting process, and F − can effectively inhibit the formation of Zn 4 (OH) 6 SO 4 ·nH 2 O during Zn stripping process. Benefiting from the synergetic effects of anion (F − ) and cation (Na + ), NaF delivers a stronger ability to suppress the formation of Zn dendrites than that of Na 2 SO 4 during stripping/platting processes. The systematic Zn//Zn cell with 0.1 M NaF as additive shows a 368 h stable cycling performance, significantly longer than those of Na 2 SO 4 (253 h) and blank sample (171 h). Our work provides a novel strategy to alleviate the growth of dendrite via optimizing the anion of additives. The excellent electrochemical performances of various Zn-based energy storage devices verify that the aqueous electrolyte with NaF additive has broad commercial prospects.
✓ 已验证
产品关联
DOI
高影响因子
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
·
2023
·Vol. 195
·期 11
·6537-6556
·
IF 3
Chen Xue-fang,Shen Zhi-jie,Ji Xu-ran,Yao Shi-miao,Wang Can,Li Hai-long,Zhang Hai-rong,Xiong Lian,Chen Xin-de
The efficient and economical removal of fermentation inhibitors from the complex system of biomass hydrolysate was one of the basics and keys in bio-chemical transformation. In this work, post-cross-linked hydrophilic-hydrophobic interpenetrating polymer networks (PMA/PS_pc IPNs and PAM/PS_pc IPNs) were proposed to remove fermentation inhibitors from sugarcane bagasse hydrolysate for the first time. PMA/PS_pc and PAM/PS_pc IPNs can obviously enhance the adsorption performance towards fermentation inhibitors due to their higher surface area and hydrophilic-hydrophobic synergetic surface properties, especially PMA/PS_pc IPNs has higher selectivity coefficients of 4.57, 4.63, 4.85, 16.0, 49.43, and 22.69, and higher adsorption capacity of 24.7 mg/g, 39.2 mg/g, 52.4 mg/g, 9.1 mg/g, 13.2 mg/g, and 144.9 mg/g towards formic acid, acetic acid, levulinic acid (LA), 5-hydroxymethylfurfural (HMF), furfural, and acid-soluble lignin (ASL), respectively, in a lower total sugar loss of 2.03%. The adsorption kinetics and isotherm of PMA/PS_pc IPNs were studied to elucidate its adsorption behavior towards fermentation inhibitors. In addition, the cyclic utilization property of PMA/PS_pc IPNs was stable. Synthesizing PMA/PS_pc IPNs is a new strategy to provide an efficient adsorbent for the removal of fermentation inhibitors from lignocellulosic hydrolysate.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nature Sustainability
·
2023
·Vol. 6
·期 6
·712-719
·
IF 27.6
Sun Bo,Zhang Jie,Wang Maolin,Yu Shixiang,Xu Yao,Tian Shuheng,Gao Zirui,Xiao Dequan,Liu Guosheng,Zhou Wu,Wang Meng,Ma Ding
Biodegradable polyesters such as polylactic acid are promising alternatives to conventional plastics as they do not accumulate in the environment upon disposal. However, their biodegradation leads to CO 2 emissions. Alternatively, waste biodegradable polyesters could serve as a carbon source for the production of value-added chemicals. Valorization of waste biodegradable polyesters not only avoids CO 2 emissions during their biodegradation but also achieves sustainable carbon use. Here, we report a two-step catalytic process to convert polylactic acid waste into methyl methacrylate, a key building-block molecule. Polylactic acid is first transformed into methyl propionate with near-quantitative yields (conversion >99%, selectivity 98%) over the α-MoC catalyst in methanol solution, which is followed by reacting the obtained methyl propionate with formaldehyde to produce methyl methacrylate with a conversion of 81% and selectivity of 90%. This study opens up a new path for managing end-of-life biodegradable polyester plastics and contributing to a circular economy.
✓ 已验证
产品关联
DOI
高影响因子
IRANIAN POLYMER JOURNAL
·
2023
·Vol. 32
·期 6
·729-737
·
IF 3.1
Wang Meng,Li Xiaodong,Li Shaolong,Li Wenke,Stewart Callum,Yang Yike,Liu Feng
Abstract The interfacial de-wetting problem of fluoropolymer/nitramine energetic composites such as F2313/RDX severely restricts their potentially extensive application as high-energy polymer bonded explosives (PBXs). The matched neutral polymeric bonding agents (NPBAs) can bridge the gap between the composite components and play a critical role in strengthening the composite interface to inhibit de-wetting. In this contribution, following the typical NBPA design strategy, two novel NPBAs with trifluoromethyl and amino pendants were prepared from methyl acrylate (MA), hydroxyethyl acrylate (HEA), trifluoroethyl methacrylate (TFEMA) and acrylamide (AM) as raw materials, under the action of initiator AIBN, named NPBA-2 and NPBA-3, respectively. The structure, interfacial characteristics, and bonding properties of the synthesized NPBAs were investigated. The results showed that the additional functional groups reduced the surface tension for interface wetting and effectively enhanced the bonding effect of NPBAs on F2313/RDX according to the “like-dissolves-like” rule and the formation of hydrogen bonds. The bonding properties of both novel NPBAs out-performed the control NPBA-1 and provided at least 184% interfacial reinforcement for F2313/RDX. The NPBA-2 bonded F2313/RDX energetic composite exhibited the best mechanical properties with a maximum Brazilian strength of 6.88 ± 0.02 MPa and the corresponding modulus of 10.71 ± 0.02 GPa. We believe that these NPBAs will have great application potential in high-energy PBXs. Graphical abstract
✓ 已验证
产品关联
DOI
高影响因子
CELLULOSE
·
2023
·Vol. 30
·期 6
·3757-3771
·
IF 5.7
Ge Yue,Lin Ning,Du Chen,Amann Tobias,Feng Hao,Yuan Chengqing,Li Ke
As the thickener for fluorine greases, polytetrafluoroethylene (PTFE) powder performs insufficient load-carrying capacity and limited assistance for friction reduction and wear resistance in the boundary lubrication regime. The present work aims to explore novel nanoparticles with higher mechanical strength as an alternative to PTFE. Cellulose nanocrystals (CNCs) were surface modified by grafting (or partially adsorbing) fluoropolymer chains and introduced into perfluoropolyether PFPE base oil. The obtained polyhexafuorobutyl methacrylate grafted CNC (CNC-g-PHFMA) powder exhibited good compatibility with the PFPE oil. The friction test and wear analysis showed that CNC-g-PHFMA formed a more intensive and stable tribo-film than PTFE on the sliding surface, resulting in more effective friction reduction (11%) and wear resistance (19%). This study demonstrates that fluoropolymer-grafted CNCs have a good application prospect in fluorine greases.
✓ 已验证
产品关联
DOI
高影响因子
Nano Research
·
2023
·Vol. 16
·期 5
·7413-7421
·
IF 9.9
Jiang Xin-Chi,Wu Hong-Hui,Zhang Tianyuan,Dong Yun-Fei,Li Yao-Sheng,Huang Ting,Tian An-Hao,Chen Peng-Xiang,Lin Xian-Ming,Huang Ying-Zhi,Liu Chong,Zhang Xiang-Nan,Chen Zhong,Tabata Yasuhiko,Gao Jian-Qing
Exosomes make a significant contribution during stem cell-based therapy due to the abundant contents. Accumulating evidence implies exosomes can act as potential biological nano agents. We herein propose hypoxic preconditioning for neural stem cells (NSCs) that could produce hypoxic exosomes for efficient treatment of ischemic stroke. Hypoxic preconditioning on NSCs significantly altered the miRNAs encapsulated in exosomes. Notably, hypoxic exosomes could target the injured brain to regulate the microenvironment to inhibit neuroinflammation and promote blood-brain barrier permeability recovery. Additionally, the autologous NSCs in Nestin-CreER mice could be activated by hypoxic exosomes to facilitate nerve regeneration. After hypoxic preconditioning, exosomes further exerted therapeutic effects on both survival (25%) and behavioral outcomes in ischemic stroke mice. Overall, hypoxic preconditioning NSCs can produce effective nano agent and may represent a promising strategy for clinical neurorestorative therapy.
✓ 已验证
产品关联
DOI
高影响因子
Silicon
·
2023
·Vol. 15
·期 10
·4325-4334
·
IF 3.4
Shi Xu,Xu Weibing,Zhou Zhengfa,Ma Haihong,Ren Fengmei
In order to improve the smoke suppression of silicone oil, relatively high nitrogen content silicone oil was synthesized by the reaction of dicyandiamide (DCD) and epoxy-terminated silicone oil (ETSO) and named DCDSO. The molecular structure of DCDSO was characterized by Fourier transform infrared spectroscopy (FT-IR) and nuclear magnetic resonance spectroscopy (NMR). The flame ignition and cone calorimetry test (CCT) were used to investigate the smoke suppression effect of DCDSO. The results showed that the introduction of DCD significantly improved the smoke suppression performance of DCDSO. When the molar ratio of the epoxy group in ETSO and the primary amino group in DCD was 1:1.3, the flame height and the total smoke production were significantly reduced. Thermogravimetric analysis (TGA), thermogravimetric infrared analysis (TG-IR) and thermal field emission scanning electron microscopy (SEM) were used to explore the mechanism of smoke suppression. The mechanism of smoke suppression is that the introduction of DCD reduces the rearrangement decomposition, promotes the free radical oxidation decomposition and the formation of condensed phase, and thus reduces the generation and release of smoke.
✓ 已验证
产品关联
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2023
·Vol. 30
·期 21
·60704-60716
·
IF 5.8
Zhang Nizi,Tang Chenliu,Bi Weixia,Sun Zhirong,Hu Xiang
Efficient removal of antibiotics from the aquatic environment is urgently needed due to their obstinate accumulation and non-biodegradability. In this study, a mesoporous carbon material (ZC-0.5) was successfully synthesized for the adsorption of sulfamethoxazole (SMX), one of the major antibiotics for the treatment of human and animal infections. ZIF-8 as the precursor of ZC-0.5, specifically, using cetyl trimethyl ammonium bromide (CTAB) and sodium laurate (SL) as dual templates and carbonizing at 800 ℃. This novel adsorbent exhibited a high proportion of mesopore (75.64%) and a large specific surface area (1459.73 m 2 ·g −1 ). The adsorption experiment examined the reusability of ZC-0.5 and that it could retain superior maximum adsorption capacities (167.45 mg∙L −1 ) after five cycles of adsorption and desorption. The adsorption process satisfied the pseudo-second-order kinetic (PSO) and mixed first- and second-order kinetic (MOE). It also satisfied the Freundlich and Sips isotherm models. Moreover, thermodynamic calculation indicated the adsorption process was spontaneous, endothermal, and entropy-increasing. Furthermore, plausible adsorption mechanisms were explained through van der Waals force, electrostatic interaction, hydrophobic force, π-π interaction, and hydrogen bond. This work offers a new efficient adsorbent for antibiotic elimination.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CELLULOSE
·
2023
·Vol. 30
·期 7
·4663-4681
·
IF 5.7
Wang Junjie,Chen Jinhao,Wang Wenwen,Lu Jing,Li Yingying,Bai Ting,Chen Jiahui,Zhu Zongmin,Wang Dong
A new boron-containing chitosan-based compound HBS was synthesized and used in combination with ammonium polyphosphate (APP) as an efficient flame retardant with good compatibility for epoxy resin. The modified EP composites were investigated by thermogravimetric analysis (TGA), UL-94 V (vertical burning), limited oxygen index (LOI) and cone calorimetry (CC) test. The sample labeled S3 with the total addition of HBS and APP was 10%, simultaneously the weight ratio of HBS and APP was 1:3, which passed the UL-94 V-0 rating. LOI value of sample S3 was 30.5%, which was higher than that of EP (S0, 22.6%) and EP modified with 10% APP (S5, 26.1%). CC tests results showed that PHRR (peak heat release rate), THR (total heat release), PSPR (peak smoke production rate) and TSP (total smoke production) values of sample S3 were 515.9 kW/m 2 , 50.6 MJ/m 2 , 0.14 m 2 /s and 10.9 m 2 , respectively, which were 51.5, 33.5, 74.5 and 84.7% lower than those of unmodified EP, respectively. What’s more, flame retardancy parameters such as fire index growth rate (FIGRA), maximum average rate of heat emission (MARHE) and average effective heat of combustion (av-EHC) also decreased. The char residue of sample S3 was 61.3%, which was 506.9% higher than that of EP. The introduction of HBS and APP was beneficial to form a sufficient, dense, homogeneous and high strength char layer on the EPs surface during combustion. Due to the effective protective layer, the transfer and diffusion of heat can be effectively inhibited, the production of combustible gases can be restricted, and the emission of smoke can be inhibited, thus reducing the release of heat and smoke.
✓ 已验证
产品关联
DOI
高影响因子
Biomaterials Research
·
2023
·Vol. 27
·期 1
·1-16
·
IF 11.3
Li Chengnan,Gan Yingying,Li Zongshao,Fu Mengjing,Li Yuzhen,Peng Xinran,Yang Yongqiang,Tian Guo-bao,Yang Yi Yan,Yuan Peiyan,Ding Xin
Background
P. aeruginosa , a highly virulent Gram-negative bacterium, can cause severe nosocomial infections, and it has developed resistance against most antibiotics. New therapeutic strategies are urgently needed to treat such bacterial infection and reduce its toxicity caused by endotoxin (lipopolysaccharide, LPS). Neutrophils have been proven to be able to target inflammation site and neutrophil membrane receptors such as Toll-like receptor-4 (TLR4) and CD14, and exhibit specific affinity to LPS. However, antibacterial delivery system based on the unique properties of neutrophils has not been reported. Methods A neutrophil-inspired antibacterial delivery system for targeted photothermal treatment, stimuli-responsive antibiotic release and endotoxin neutralization is reported in this study. Specifically, the photothermal reagent indocyanine green (ICG) and antibiotic rifampicin (RIF) are co-loaded into poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NP-ICG/RIF), followed by coating with neutrophil membrane to obtain antibacterial delivery system (NM-NP-ICG/RIF). The inflammation targeting properties, synergistic antibacterial activity of photothermal therapy and antibiotic treatment, and endotoxin neutralization have been studied in vitro. A P. aeruginosa -induced murine skin abscess infection model has been used to evaluate the therapeutic efficacy of the NM-NP-ICG/RIF. Results Once irradiated by near-infrared lasers, the heat generated by NP-ICG/RIF triggers the release of RIF and ICG, resulting in a synergistic chemo-photothermal antibacterial effect against P. aeruginosa (~ 99.99% killing efficiency in 5 min). After coating with neutrophil-like cell membrane vesicles (NMVs), the nanoparticles (NM-NP-ICG/RIF) specifically bind to inflammatory vascular endothelial cells in infectious site, endowing the nanoparticles with an infection microenvironment targeting function to enhance retention time. Importantly, it is discovered for the first time that NMVs-coated nanoparticles are able to neutralize endotoxins. The P. aeruginosa murine skin abscess infection model further demonstrates the in vivo therapeutic efficacy of NM-NP-ICG/RIF. Conclusion The neutrophil-inspired antibacterial delivery system (NM-NP-ICG/RIF) is capable of targeting infection microenvironment, neutralizing endotoxin, and eradicating bacteria through a synergistic effect of photothermal therapy and antibiotic treatment. This drug delivery system made from FDA-approved compounds provides a promising approach to fighting against hard-to-treat bacterial infections.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
·
2023
·Vol. 45
·期 7
·5053-5065
·
IF 4.2
Xu Lei,Lu Yu-ting,Wu Dong-feng,Li Xuan,Song Min,Hang Tai-jun,Su Meng-xiang
Wastewater-based epidemiology (WBE) is an objective approach for the estimation of population-level exposure to a wide range of substances, in which the use of a population biomarker (PB) could significantly reduce back-calculation errors. Although some endogenous or exogenous compounds such as cotinine and other hormones have been developed as PBs, more PBs still need to be identified and evaluated. This study aimed to propose a novel method to estimate population parameters from the mass load of metal ion biomarkers in wastewater, and estimate the consumption of tobacco in 24 cities in Southern China using the developed method. Daily wastewater samples were collected from 234 wastewater treatment plants (WWTPs) in 24 cities in Southern China. Atomic absorption spectroscopy (AAS) was applied to determine the concentrations of common health-related metal ions in wastewater, including sodium (Na), potassium (K), magnesium (Mg), calcium (Ca), iron (Fe), and zinc (Zn), and compared them with the daily mass load of cotinine corresponding to catchment populations. The concentrations of cotinine in wastewater samples were measured using liquid chromatography-tandem mass spectrometry. There were clear and strong correlations between the target metal ion equivalent population and census data. The correlation coefficients ( R ) were R K = 0.78, R Na = 0.66, R Ca = 0.81, R Mg = 0.77, and R Fe = 0.69, at p < 0.01 and R 2 > 0.6. Subsequently, the combination of WBE and metal ion PBs was used to estimate tobacco consumption. Daily consumption of nicotine was estimated to be approximately 1.76 ± 1.19 mg/d/capita, equivalent to an average of 13.0 ± 8.75 cigarettes/d being consumed by smokers. The data on tobacco consumption in this study were consistent with those in traditional surveys in Southern China. The metal ion potassium is an appropriate PB for reflecting the real-time population and could be used to evaluate the tobacco consumption in WBE study.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）