FOOD CHEMISTRY
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2024
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IF 8.5
Linlin Li,Li Xia,Feng Xiao,Yewen Xiao,Wei Ji,Baocai Xu,Hualin Wang
Using novel active food packaging has gradually become a daily necessity in terms of impeding microbial contamination. Here, an antimicrobial photodynamic inactivation (PDI) pH-responsive film is developed by incorporating aloe-emodin (AE) into a vehicle of gelatin/chitosan (GC). Besides enhancement in hydrophobicity, the well-dispersed crystals of AE in the GC matrix by hydrogen bonding can upgrade the film's mechanical strength and barrier. The matrix is capable of regulating the release of AE in response to acidic stimuli by a combination mechanism of diffusion and polymer relaxation. Being benefitted from the inherent bioactivity of AE and the PDI activity under visible light irradiation (i.e., 456 nm), the target film of GC-AE2 has excellent antibacterial effect towards Staphylococcus aureus and Escherichia coli , showing bacterial viability of 9.93 ± 1.33 % and 14.85 ± 1.16 %, respectively. Furthermore, the film can effectively thwart Botrytis cinerea infection in cherry tomatoes, demonstrating its potential in preventing the microbial spoilage of postharvest fruits.
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Soft Matter
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2012
·Vol. 8
·期 16
·4382-4389
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IF 4.39
Yujia Su,Qian Zhao,Jianzhong Sun,Jingjun Wu
Biodegradable macroporous hydrogels were prepared using a biodegradable crosslinker based on chitosan derivatives. The chitosan crosslinker was synthesized through the amidating reaction of amino groups in the chitosan oligosaccharide (CSO) chains and carboxyl groups in acrylic acid (AA) under the catalysis of 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimidehydro-chloride (EDC) and N-hydroxysuccinimide (NHS). The amidating reaction is able to provide polymerizable carbon–carbon double bonds for CSO. The chemical structure of the resulting compound chitosan oligosaccharide-graft-acrylic acid (CSO-g-AA) was characterized by Fourier transform infrared spectroscopy (FTIR) and 1H nuclear magnetic resonance (1H NMR) spectroscopy. The content of double bonds was measured by titration analysis. The measurement showed a grafting ratio of AA on CSO of about 3.5% (on average two acryoyl groups per CSO-g-AA chain) when the applied molar ratio of AA to CSO was 1.0. Polyacrylamide (PAM) cryogels were synthesized by the free radical polymerization of acrylamide using a modified freezing polymerization method crosslinked by CSO-g-AA. The obtained cryogels were macroporous hydrogels which could be degraded into solutions of linear polymer chains when treated with appropriate enzymes. Then we used snailase as a model enzyme to study the biodegradation process. The degradation was monitored by morphological studies using a confocal laser scanning microscope (CLSM) and scanning electron microscope (SEM), mechanical strength, and swelling ratio. The duration of the degradation process was adjustable from one month to two months when using different concentrations of snailase solutions.
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COLLOIDS AND SURFACES B-BIOINTERFACES
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2012
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IF 3.456
Lulu Fan,Miao Li,Zhen Lv,Min Sun,Chuannan Luo,Fuguang Lu,Huamin Qiu
The adsorption characteristics of hydroquinol from aqueous solutions onto the β-cyclodextrin modified magnetic chitosan nanoparticles (CMCN) had been investigated. The characteristics results of FTIR , SEM and XRD showed that CMCN was successfully prepared. The influences of the pH of the solution and the contact time on the adsorption amounts had been discussed, and the appropriate process conditions for the adsorption of hydroquinol had been obtained. Equilibrium experiments fitted well with the Freundlich isotherm model, and the maximum adsorption capacity of the CMCN at 303 K was determined to be 1.75 mmol/g for hydroquinol at the concentration of 9.0 mmol/L, much higher than some conventional adsorbents. The CMCN was stable and easily recovered. Moreover, the adsorption capacity was about 90% of the initial saturation adsorption capacity after being used four times.
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Biomaterials Advances
·
2025
·
IF 6
Pu Hou,Kun Lei,Zhishen Zhang,Pengchao Zhao,Jinghua Li,Guangda Li,Jianfeng Bao,Xin Li,Yun Xue,Chunshan Quan,Fangfang Fu
Hydrogels possessing appropriate adhesion and antibacterial properties have emerged as promising dressings for expediting wound healing, while also providing the convenience of visualizing the wound site to accurately monitor the healing process. In this study, we incorporated oxidized and degraded polydopamine nanoparticles into quaternized chitosan/oxidized dextran hydrogel QOP series, resulting in enhanced transmittance exceeding 95 % and adhesion strengths reaching up to 19.4 kPa. Moreover, these hydrogels exhibit a well-defined porous structure, rapid gelling ability (<50 s), exceptional self-healing capacity, and a swelling rate surpassing 760 %. Furthermore, the QOP hydrogels demonstrate outstanding hemocompatibility (hemolysis rate < 3 %) and cytocompatibility (cell viability >100 %). In addition, they display potent inhibition against Staphylococcus aureus , methicillin-resistant S. aureus (MRSA), Staphylococcus pasteuri and Escherichia coli , with bactericidal rates exceeded 90 %. The closure of MRSA-infected wounds along with H&E and Masson staining analysis revealed that QOP hydrogels can expedite wound healing by stimulating collagen deposition and facilitating angiogenesis.
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JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
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2025
·
IF 4.7
Jinzhao Shu,Zhiguo Hou,Yuqi Zhang,Xueyi Dong,Yue Zhang,Qiangwei Liu,Shijun Kang,Mingliang Liu,Sen Wang,Bin Yang,Jiasheng Qian
In this paper, PVA/CS/CuS-based antibacterial hydrogel was prepared by a simple method. The CuS-based particles were characterized using zeta potentiometers, X-ray diffraction, X-ray photoelectron spectroscopy, transmission electron microscopy, and scanning electron microscopy. These analyses verified the successful synthesis of CuS@PDA and CuS@PDA@Ag particles. The composite hydrogel exhibited good photothermal effect and antibacterial activity, with silver doping significantly improving its photocatalytic performance. Under 808 nm near-infrared light irradiation, the hydrogel exhibited excellent photothermal conversion ability, with the maximum temperatures of the three hydrogels being 59.2 °C, 61.5 °C, and 64.8 °C, respectively. After 10-minute irradiation, the composite hydrogel exhibited obvious antibacterial activity due to the synergistic effect of hyperthermia and reactive oxygen species, resulting in a bactericidal efficiency of 96.2 % against E. coli and 98.4 % against S. aureus.
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JOURNAL OF HAZARDOUS MATERIALS
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2017
·
IF 6.065
Chaoting Shi,Caizhi Lv,Lan Wu,Xiandeng Hou
The unique characteristics of Chitosan (CS) such as resource abundance, good biocompatibility, film-forming ability and sufficient sites ( NH 2 and OH) for adsorption of heavy metals or organic pollutants make CS-based membranes a promising membrane adsorbent. In this work, a porous Chitosan/Hydroxyapatite (CS/HA) membrane with a sponge-like surface and a three-dimensional interpenetrated porous structure of about mean pore size less than 10 μm was developed. The most striking advantage of the proposed membrane lies on the integration of appreciably high adsorption capacity (as compared with current CS-based membranes, also 2.5 times and 4 times higher than that of non-porous CS/HA membrane and the commercially available activate carbon) and the high-speed dynamic dye removal (98% or even better in less than 15 min). Besides, the synthesis protocol for the proposed membrane is also much simpler, environmental-friendly and economical. Moreover, the proposed membrane also featured repeated dye removal (above 80% after 5 cycles of dynamic adsorption at dye concentration of 150 mg L −1 ). All the above advantages indicated the intriguing potential of the porous membrane in practical wastewater treatment .
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
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IF 7.7
Fangcong Hua,Zonghui Zhang,Zhibo Zhao,Xiaohong Hou,Jianhua Qu,Chongning Lv,Qi Hu
Quaternary-ammonium chitosan (CT-CTA) is a popular water treatment agent, and its electropositivity and cation strength are improved compared with chitosan. The use of CT-CTA is widely advocated to remove suspended particles and organic matter from wastewater. However, the solubility of CT-CTA is an important factor affecting the performance of CT-CTA, which is a neglected problem in previous studies. In the study, CT-CTA with different solubilities were prepared by adjusting pH from 2 to 7 in preparation, and their applications were explored in wastewater. When the pH was 2, 2.5, or 3, the obtained CT-CTA was a dissolved state. The turbidity and color removal were 95 % - 98 % and 60 % - 74 %, respectively. When the pH was 4, 5, 6, or 7, the obtained CT-CTA was a solid state. The turbidity and color removal were 30 % - 63 % and 90 % - 97 %, respectively. For domestic-wastewater treatment, CT-CTA in a dissolved state removed 92 % of turbidity and 50 % of chemical oxygen demand (COD). CT-CTA in a solid state removed 86 % of turbidity and 64 % of COD with poly aluminum chloride (PAC). The results illustrated the performance of CT-CTA with different solubilities, which can broaden its application in wastewater treatment .
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FOOD CHEMISTRY
·
2024
·
IF 8.5
Kejin Yu,Lina Yang,Siyu Zhang,Ning Zhang,Danshi Zhu,Yutang He,Xuehui Cao,He Liu
This study focused on extracting nanocellulose from food processing waste to create a multi-functional edible coating for preserving grapes. Nanocellulose, in the form of short rods with diameters ranging from 30 to 130 nm, was extracted from soy hulls. Edible coatings were then prepared through an ion cross-linking method. Results revealed that the film surfaces and cross-sections were smooth, flat and pore-free, with monomers cross-linked through hydrogen bonding, ester bonds and electrostatic interactions. Further, the incorporation of soy-hull nanocellulose (2 g) effectively improved the mechanical strength (elongation = 281.03 % and tensile strength = 114.88 MPa), barrier properties and antifogging and antibacterial properties (95.55 %) of SCT composite films. Moreover, compared with the control, the SCT-3 coating can extend the shelf life of grapes to 10 d at 25 °C. This study offers a new perspective on the high-value use of agricultural by-products and development of edible films.
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THIN SOLID FILMS
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2024
·
IF 2
Tran Dung Hoang,Thuy Chinh Nguyen,Thanh Tung Doan,Thanh Dung Ngo,Thi Yen Nguyen,Ba Thanh Ngo,Thanh Thuy Tran,Trong Lu Le
Polyvinyl alcohol (PVA) is a widely used polymer in the electrospinning technique. It is water-soluble, which limits the application of electrospun PVA matrix. In this study, chitosan (CS) and biosynthesized TiO 2 @Ag nanoparticles were incorporated into PVA to enhance its antibacterial properties and photocatalysis. The PVA/CS/TiO 2 @Ag nanofiber mat was prepared using the electrospinning method with a voltage of 20 kV, a needle-collector distance of 15 cm, and a flow rate of 0.5 mL. h − 1 . The concentrations of the PVA and CS solutions were 10% and 2%, respectively. The TiO 2 @Ag nanoparticles were synthesized using AgNO 3 solution, TiO 2 nanoparticles as precursors, and Cleistocalyx operculatus leaf extract as a reducing agent. The morphology and structure of the PVA/CS/TiO 2 @Ag nanofiber mat were analyzed using scanning electron microscopy and infrared spectroscopy. The PVA/CS/TiO 2 @Ag nanofibers exhibited an average fibril diameter of 116.4 nm. Additionally, the antibacterial activity against Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ), as well as the photocatalytic properties of these mats, were assessed. The results indicated that the addition of CS and TiO 2 @Ag led to changes in the hydrophilic properties and antibacterial efficacy of PVA. The inhibition zones of the PVA/CS/TiO 2 @Ag nanofiber mat against E. coli and S. aureus were measured at 5 and 4 mm, respectively. The water contact angle of PVA/CS/TiO 2 @Ag nanofiber mat showed a significant increase. The PVA/CS/TiO 2 @Ag nanofibers were able to degrade 94.56 ± 0.57% and 98.17 ± 0.11% of methylene blue dye under sunlight irradiation after 10 and 20 min of exposure, respectively. These findings suggest that the PVA/CS/TiO 2 @Ag nanofiber mat has the potential for applications in the textile industry or medicinal field as antibacterial and photocatalytic coatings.
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CARBOHYDRATE RESEARCH
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2024
·
IF 2.4
Lin Wang,Meihua Xin,Mingchun Li,Tao Zhang,Yu Pang,Yangfan Mao
N -(4- N ′-pyridine-benzylcarbonyl chloride) chitosan (CBPyC), N - p -biguanidine benzoyl chitosan (CSBG), and N -( p -biguanidine -1-pyridine-4-benzylcarbonyl chloride) chitosan (CSQPG) were synthesized. The structures of prepared chitosan derivatives were characterized using nuclear magnetic resonance spectroscopy (NMR) and ultraviolet–visible (UV–vis) spectroscopy, and the degree of substitution was determined through elemental analysis (EA) and evaluated on the basis of the integral values in 1 H NMR. The antibacterial activities of chitosan derivatives against Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) were investigated in vitro using antibacterial rate, minimal inhibitory concentration and minimum bacterial concentration assays. The antibiofilm activity was also assessed using the crystal violet assay. CSQPC exhibited higher antibacterial and antibiofilm activities against E. coli and S. aureus compared to CBPyC and CSBG. The antibacterial rate of CSQPG against E. coli and S. aureus at a concentration of 0.5 mg/mL was 43.3% and 100%, respectively. The biofilm inhibition rate of CSQPG at 0.5 MIC against E. coli and S. aureus was 56.5% and 69.1%, respectively. At a concentration of 2.5 mg/mL, the biofilm removal rates of E. coli and S. aureus were 72.9% and 90.1%, respectively. The antibacterial and antibiofilm activities of CSQPG were better than CSBG and CBPyC, and the combination of guanidine and quaternary ammonium further improved the positive charge density of chitosan and enhanced its antibacterial activity.
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JOURNAL OF MOLECULAR LIQUIDS
·
2024
·
IF 5.3
Zhuoyu Yin,Likang Fu,Hongliang Liu,Na Xiong,Xingmei Wang,Shixing Wang,Yingbi Chen,Chen Wang
Cu(II) has garnered significant attention due to its adverse effects on the environment and human health. To address this issue, researchers developed a magnetic chitosan material (MnFe 2 O 4 -CS) as an adsorbent, exhibiting remarkable properties for effective Cu(II) capture and offering repeatability. MnFe 2 O 4 -CS features abundant nitrogen-containing functional groups that enhance its adsorption performance. Additionally, MnFe 2 O 4 -CS possesses excellent saturation magnetization, enabling easy removal from water. Experimental findings reveal that MnFe 2 O 4 -CS achieves an impressive Cu(II) removal rate of 99.8%. With an adsorption capacity of up to 103.6 mg/g. The fitting results demonstrated that the isothermal process followed the Redlich-Peterson model, indicating a complex adsorption behavior of Cu(II) by MnFe 2 O 4 -CS. The kinetic process followed a pseudo-second-order model, and the thermodynamic parameters prove that the present study is a heat-absorption reaction. The kinetics and thermodynamics prove that the adsorption of Cu(II) by MnFe 2 O 4 -CS is a chemisorption. MnFe 2 O 4 -CS maintains a high removal capacity for Cu(II) in aqueous solutions after six cycles. In summary, MnFe 2 O 4 -CS quickly and efficiently adsorbs Cu(II) ions, showing potential for practical application in heavy metals removal.
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FOOD HYDROCOLLOIDS
·
2025
·
IF 12.4
Fuyuan Ding,Lin Fu,Xiaowei Huang,Jiyong Shi,Megan Povey,Xiaobo Zou
Self-healing hydrogels prepared with biopolymers have been widely applied in various engineering fields. In this study, the carboxymethyl chitosan (CMC) hydrogels were fabricated through crosslinking with oxidized alginate (ADA), which can be applied in smart food packaging fields. The concentration of oxidized alginate has greatest impact on the physicochemical properties of the hydrogels. Due to the dynamic properties of Schiff base linkages and hydrogen bonds, the hydrogel demonstrated self-healing. Higher concentrations of oxidized alginate result in weaker self-healing ability of the hydrogels. The self-healing properties endowed the hydrogel with 3D printable capacity. The anthocyanin (An) in the hydrogel exhibited a color change when exposed to acidic and basic gases, making the hydrogel potentially useful for smart indicators. These intelligent indicators can be used to detect the freshness of chicken, pork and fish. In addition, the hydrogel showed excellent biodegradable properties and can be degraded in lake, soil and simulated seawater. The self-healing, biodegradable and pH sensitive hydrogels has the potential to be applied in smart food packaging.
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