MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 11
·1-10
·
IF 5.3
Li Ming-Yan,Yu Yaqi,Zhang Rui-Qiao,Qiu Zhiwei,Li Xiang,Wang Ying-Hui,Qi JiaYi,Zeng Jingbin,Wen Cong-Ying
A label-free colorimetric biosensor based on Au@Ag@AgCl core-shell nanomaterials has been developed. The biosensor operated through a unique mechanism where Au@Ag@AgCl nanoparticles were progressively etched by ammonia produced during urease-catalyzed urea decomposition. This etching process induced a distinct color transition of the colloidal solution from orange to pink and ultimately to red, enabling quantitative determination of urease concentration. The multi-core-shell design of Au@Ag@AgCl provided highly enriched color gradients and significantly enhanced visual resolution, achieving a detection limit of 0.147 U/mL, which was 85 times lower than that of the commercial urease test strips. Notably, the assay required no complex surface modifications or separation procedures, offering high operational simplicity which could be accomplished within 15 min. All these advantages greatly facilitated in-situ and in-time detection of urease. Finally, this assay was applied to the detection of simulated saliva samples with recoveries ranging from 104.4% to 123.0%, thereby validating its robust anti-interference capability and potential application in practice. Thus, the proposed Au@Ag@AgCl core-shell nanostructure-based label-free biosensor might provide a rapid, quantitative, and user-friendly alternative approach for monitoring Heliobacter pylori infection. Graphical
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Chem Catalysis
·
2024
·
IF 11.5
Ji Wei Sun,Tingting Yu,Haoran Wu,Minghui Zhu,Aiping Chen,Cheng Lian,Hua Gui Yang,Peng Fei Liu
High cost of pure CO 2 feed constitutes a significant economic obstacle in industrial-scale CO 2 electrolysis. Direct CO 2 electrochemical conversion from flue gas has emerged as a promising strategy to reduce feed cost, while the O 2 in flue gas cannot be ignored due to its strong reactivity. Here, we achieved fast, selective CO electrosynthesis directly fed with simulated oxygen-containing flue gas (95% CO 2 +5% O 2 ) over the amine-confined Ag catalysts in a flow cell, among which dimethylamine-modified Ag exhibited 80.6% CO Faradaic efficiency with partial current density of 333.7 mA cm −2 . In situ spectroscopy demonstrated that dimethylamine confinement endows a robust CO 2 adsorption-conversion capacity. Theoretical calculations further elucidated that amine modification could not only mediate CO 2 adsorption and ∗COOH intermediate formation but could also block the ∗OOH intermediate pathway in the side reaction of oxygen reduction. These findings pave a new avenue for rational design of amine-confined electrocatalysts for direct flue gas conversion and utilization.
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CERAMICS INTERNATIONAL
·
2025
·
IF 5.6
Shuimiao Xia,Yang Quan,Zelong Chang,Davoud Dastan,Zhicheng Shi
High-performance polymer composites with excellent dielectric and energy storage capabilities are urgently needed for advanced electronic power systems, but traditional strategies have been challenging to balance high dielectric constant, low loss and breakdown strength. Herein, an innovative Au/Ag/BaTiO 3 composite skeleton is prepared by loading Au/Ag bimetallic nanoparticles onto BaTiO 3 . In which, Ag nanoparticles are loaded inside of BaTiO 3 by in-situ growth. The Au nanoparticles are loaded on the surface of BaTiO 3 via physical vapor deposition. The BaTiO 3 skeleton plays a dual role in high polarization and blocking the formation of conductive pathways by metal nanoparticles. The results show that the Au/Ag/BaTiO 3 /PVDF nanocomposites exhibit a high dielectric constant of 56.6 at 10 kHz, which is 590 % higher than that of pure PVDF ( 8.2@10 kHz) due to the micro-capacitors effect induced by Au/Ag bimetallic nanoparticles. Due to the Coulomb blockade effect of Au nanoparticles, the dielectric loss of the composites is only 0.037 at 10 kHz, which is 24.5 % lower than that of pure PVDF ( 0.049@10 kHz). Notably, the nanocomposite achieves simultaneously a breakdown strength of 294 kV/mm and an energy density of 6.9 J/cm 3 , which are 141 % and 578 % of pure PVDF, respectively. Mechanical tests show that the skeleton also improves the Young's modulus of the composites (1700 MPa compared to 520 MPa for PVDF). The results demonstrate the potential of Au/Ag/BaTiO 3 composite skeletons for high-performance dielectric applications and provide a new strategy for designing advanced polymer composites.
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ENERGY & FUELS
·
2025
·
IF 5.3
Wenhui Ma,Li Li,Yan Lin,Fei Wang
The use of a fixed bed has emerged as an effective approach to enhance methane hydrate formation for energy storage. In this study, a novel fixed bed was developed by incorporating Ag nanoparticles, which could serve as hydrate nucleation sites to ultralight graphene aerogel (Ag@GA) and then evaluated in methane hydrate formation. The presence of Ag nanoparticles on the fixed bed enhanced the hydrate nucleation dramatically, which shortened the induction time from 775.3 ± 186.66 min without Ag nanoparticles to 0–15 min. With the increase in the initial pressure (5–8 MPa), the hydrate growth rate ascended gradually from 0.063 to 0.26 mol/min/L, while the mass storage capacity remained stable at a high level of 0.120–0.126 g/g. The temperature in the range 273.15–276.15 K did not produce an obvious influence on both the hydrate formation kinetics and methane storage efficiency. However, the concentration of the kinetic promoter (l-methionine) dominated the hydrate formation significantly, especially the hydrate growth rate and morphology. At a low l-Met concentration (1 g/L), hydrates formed majorly in the inner pores of the fixed bed with a high growth rate (0.27 mol/min/L), while with the l-Met concentration increased to 2, 3, and 4 g/L, hydrates tended to grow out of the fixed bed and accumulated on the top and lateral surface. The morphology of hydrates varied from acicular crystals to hydrate blocks, and the hydrate growth rate decreased to 0.099 mol/min/L and then increased to 0.17 and 0.25 mol/min/L. Moreover, the excellent cyclic performance of Ag@GA was confirmed in five cycles of hydrate formation and dissociation, in which the induction time was 0–8.3 min, the hydrate growth rate reached 0.254–0.263 mol/min/L, and the methane storage capacity was kept at 135–145 V/V. This study provides an effective pathway for the application of ultralight fixed beds in hydrate-based natural gas storage and transportation.
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Polymers
·
2025
·Vol. 17
·期 12
·1716
·
IF 4.9
Lili Kong,Xinna Yu,Qifang Sun,Meizhen Huang,Tianyuan Liu,Jie Chen
Polycyclic aromatic hydrocarbons (PAHs) have attracted significant attention due to their severe threats to both ecological systems and human health. In this paper, a high-performance surface-enhanced Raman spectroscopy (SERS) substrate based on NCF/GO/Au@Ag nanocomposites was developed, which enabled sensitive and stable detection of PAHs. The NCF/GO/Au@Ag substrate synergistic utilizes the localized surface plasmon resonance (LSPR) effect of Au@Ag core–shell nanorods and the additional interfacial charge transfer provided by graphene oxide (GO) to exhibit extremely high sensitivity. And the three-dimensional fibrous network of nanocellulose (NCF) improved nanoparticle dispersion uniformity. Combined finite element simulations and experimental studies verified that the dual plasmonic resonances (512 nm and 772 nm) of Au@Ag nanorods optimally match 785 nm excitation, yielding an enhancement factor of 5.21 × 10 5 . GO integration enhanced Raman signals by 1.68-fold through interfacial charge transfer, while the introduction of NCF reduced the signal relative standard deviation (RSD) from 36.88% to 4.29%. The NCF/GO/Au@Ag substrate achieved a detection limit of 10 μg/L for PAHs, demonstrating exceptional sensitivity and reproducibility.
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CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Songhao Luo,Zhifeng Liu,Yang Liu,Eydhah Almatrafi,Binbin Shao,Biao Song,Chengyun Zhou,Yukui Fu,Miao He,Zhuotong Zeng,Guangming Zeng
4-nitrophenol (4-NP) in industrial wastewater is harmful to both ecological environment and human health even in the very low concentration in the environment. Catalytic hydrogenation, which converts toxic pollutants from wastewater into high-value industrial feedstocks, is a coveted treatment option, but the design of suitable catalysts has been a challenge in the field. In this work, the functionalized conjugated microporous polymers (CMPs) anchored Ag nanocatalysts could effectively catalyze the hydrogenation of 4-NP in wastewater to 4-aminophenol (4-AP) with the rate constant k of 0.01544 s −1 . We further optimized the morphology of the CMP substrate to stabilize Ag nanocatalysts and integrated the composite into a modular unit for continuous flow wastewater treatment with an outstanding permeation flux of 1603 L m −2 h −1 (LMH). These findings provide an effective strategy to design noble metal catalysts for catalytic hydrogenation and could potentially be modularized for use in mountainous and isolated communities.
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2020
·Vol. 22
·期 1
·105
·
IF 4.556
Wanting Li,Zixuan Huang,Rui Cai,Wan Yang,Huawei He,Yejing Wang
Silver-based hybrid nanomaterials are receiving increasing attention as potential alternatives for traditional antimicrobial agents. Here, we proposed a simple and eco-friendly strategy to efficiently assemble zinc oxide nanoparticles (ZnO) and silver nanoparticles (AgNPs) on sericin-agarose composite film to impart superior antimicrobial activity. Based on a layer-by-layer self-assembly strategy, AgNPs and ZnO were immobilized on sericin-agarose films using the adhesion property of polydopamine. Scanning electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray powder diffraction spectroscopy were used to show the morphology of AgNPs and ZnO on the surface of the composite film and analyze the composition and structure of AgNPs and ZnO, respectively. Water contact angle, swelling ratio, and mechanical property were determined to characterize the hydrophilicity, water absorption ability, and mechanical properties of the composite films. In addition, the antibacterial activity of the composite film was evaluated against Gram-positive and Gram-negative bacteria. The results showed that the composite film not only has desirable hydrophilicity, high water absorption ability, and favorable mechanical properties but also exhibits excellent antimicrobial activity against both Gram-positive and Gram-negative bacteria. It has shown great potential as a novel antimicrobial biomaterial for wound dressing, artificial skin, and tissue engineering.Keywords:sericin;AgNPs;ZnO;antimicrobial activity;green synthesis
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2021
·
IF 5.316
Mengting Liu,Wanyu Zhang,Ping Xu,Wenlong Tu,Edison Huixiang Ang,Yue Zhang,Jie Cheng,Miao Wang,Rongrong Du,Xia Yang,Fu Yang,Dawei Yu,Aihua Yuan,Yiyan Song
The complexity of environmental pollution poses a severe threat to public health, attracting considerable interest in the search for functional nanomaterials for dye removal and direct disinfection together in wastewater. Herein, we present a deft synthetic strategy for constructing Ag functionalized hierarchically structured nanosilica (Ag modified mesoporous silica/Ag-ms) using micelle termination incorporating Ag ions as a functional metallomicelle template. The results showed that multiple active Ag cores were decorated into silica nanospheres . The resulting silica has ultrahigh porous properties (1370 m 2 g −1 , 1.583 m 3 g −1 ) which are much superior to those of reports, thereby could make it a superior catalyst and disinfector. The obtained nanocomposites were carefully characterized using various advanced techniques to identify their special configuration and status of silver nanospecies in the silica. In addition, the cell viability test via cell counting kit-8 (CCK-8) assay displayed good biocompatibility of obtained Ag-ms, suggesting its promising candidate possibility for biomedical applications. Furthermore, the rapid catalytic reduction of methylene blue (MB) was easily enabled by the optimized Ag ms (0.15 Ag ms) within 5 min, which exhibited great catalytic kinetic properties (4.059 min −1 mg −1 ). Our results also showed that 0.15 Ag-ms had superior antibacterial properties against gram-negative Pseudomonas aeruginosa , gram-positive Staphylococcus aureus , and even multidrug-resistant (MDR) strain of Mycobacterium tuberculosis compared to other counterparts (0.05 Ag-ms and 0.1 Ag ms), which affords great value for reducing antibiotic-resistant bacteria and nosocomial infections.
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Journal of Biomedical Nanotechnology
·
2022
·Vol. 18
·期 9
·2264-2277
·
IF 3.641
Du Lidong,Zhang Ruoyu,Zhao Lei,Tang Shaojian,Hou Zhaohua,Xue Peng
Aim: To assess the anticancer activity of nanoparticles synthesized via a green method using American ginseng (AG). Methods: Stem-leaf saponins from AG (SAG) and heat-transformed stem-leaf saponins from AG (TSAG) were used to synthesize different SAG nanoparticles (SAG-NPs)
and TSAG nanoparticles (TSAG-NPs). The NPs were characterized, and their anticancer activity was assessed in vitro. Results: The NPs, which differed in size (16.69 nm∼253.8 nm), were spherical or polyhedral with a low PDI and good stability. The TSAG-NPs inhibited cancer
cells by inhibiting proliferation, promoting cancer cell apoptosis and directly leading cancer cells to necrosis. The small cell lung cancer cell line (SCLC) NCI-H446 was the most sensitive to the TSAG-AgNPs, with an IC50 value of 20.71±2.38 μg/mL, and the TSAG-AgNPs
inhibited invasiveness and reduced the risk of metastasis. Conclusion: TSAG-AgNPs, selected from many SAG-NPs and TSAG-NPs, are sensitive to SCLC and provide a new approach to the currently limited treatment.
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CARBOHYDRATE POLYMERS
·
2021
·
IF 9.381
Feng Gao,Yifang Mi,Xinlei Wu,Jun Yao,Qi Qi,Wei Chen,Zhihai Cao
It is an urgent task to exploit effective antimicrobial agents due to the rise of drug-resistant pathogens. Herein, antimicrobial quaternized chitosan/Ag composite nanogels (QCS/Ag CNGs) with tunable properties were fabricated through inverse miniemulsion technique with a high encapsulation efficiency of NH 2 -Ag nanoparticles (NPs). The QCS/Ag CNGs possess superior broad-spectrum antimicrobial activity and low biotoxicity, via synergistic sterilization of Ag NPs and QCS. Furthermore, the NH 2 -Ag NPs were chemically linked to the QCS matrix through Schiff base reactions, and the QCS/Ag CNGs have reactive groups, making it possible to obtain durable antibacterial cotton fabrics. Thus, QCS/Ag CNGs modified cotton fabrics exhibited laundering durability of antimicrobial effect after 100 washing cycles without sacrificing other inherent properties of cotton fabrics. Our study provides a facile and controllable method to construct polymer/inorganic CNGs to address the urgent need for antibacterial agents/fabrics.
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Biomaterials Science
·
2022
·Vol. 10
·期 7
·1812-1820
·
IF 7.59
Yanping Xu,Dinghu Zhang,Jie Lin,Xiaoxia Wu,Xiawei Xu,Ozioma Udochukwu Akakuru,Hao Zhang,Zhewei Zhang,Yujiao Xie,Aiguo Wu,Guoliang Shao
Circulating tumor cells (CTCs) usually shed from primary and metastatic tumors serve as an important tumor marker, and easily cause fatal distant metastasis in cancer patients. Accurately and effectively detecting CTCs in a peripheral blood sample is of great significance in early tumor diagnosis, efficacy evaluation, and postoperative condition monitoring. In this work, a TiO2@Ag nanostructure is structured as a SERS substrate, rhodamine 6G (R6G) is used as a Raman signal molecule, the reduced bovine serum protein (rBSA) acts as a protective agent, and folic acid (FA) acts as a target molecule to specifically recognize cancer cells. A TiO2@Ag-based SERS bioprobe is successfully prepared with the feature of ultrahigh sensitivity, good specificity, low toxicity, and high accuracy in CTC detection. The remarkable SERS activity of the TiO2@Ag nanostructure is synergistically contributed by surface plasmon resonance and photon-induced charge transfer mechanism. The limit of detection for rhodamine 6G (R6G) molecules adsorbed on the TiO2@Ag SERS substrate is 5 × 10−14 M, and the corresponding SERS enhancement factor can reach 7.61 × 107. The designed TiO2@Ag–R6G–rBSA–FA SERS bioprobe is effectively utilized in detecting various cancer cells in rabbit blood, and the limit of detection (LOD) for the target cancer cell is 1 cell per mL. Notably, CTCs in peripheral blood of six clinical liver cancer patients are successfully recognized via the TiO2@Ag-based SERS bioprobe. Accurately recognizing CTCs in peripheral blood based on the TiO2@Ag–R6G–rBSA–FA SERS bioprobe is also carefully verified by in situ immunofluorescence staining experiments, which directly supports the CTC detection accuracy of the SERS strategy. These results demonstrate that the TiO2@Ag-based SERS bioprobe has great application potential in early screening and diagnosis of tumors.
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Small
·
2025
·
IF 12.1
Xiaohang Yang,Zhiqiang Sun,Panxin Wang,Qi Wang,Qiong Li,Xingbo Bian
Soil salinity is a critical abiotic stressor that disrupts plant growth by impairing redox balance, membrane stability, and metabolic coordination. While nanomaterials have emerged as promising abiotic stress modulators, the influence of nanoscale architecture on multi-level plant responses remains insufficiently understood. Here, we report the design and application of pinwheel-like α-Fe 2 O 3 @Ag nanohybrids, engineered through controlled hydrolysis, ball milling, and high-temperature calcination, to reprogram salt stress responses across physiological and molecular scales. These hybrids exhibit hierarchical anisotropic structures that promote leaf adhesion, cellular uptake, and redox interface activity. Integrated multi-omics analyses reveal that α-Fe 2 O 3 @Ag enhances stress tolerance by modulating antioxidant defense, preserving photosynthetic efficiency, and rebalancing osmotic and hormonal pathways. At the molecular level, the nanohybrids induce transcriptomic and metabolomic rewiring across key axes, including unsaturated fatty acid metabolism, sulfur assimilation, hormone signaling (ABA and JA), and protein turnover. This study presents a structure-function-response framework linking nanomaterial morphology to biological outcomes, and highlights the potential of hybrid nanoregulators as versatile tools for enhancing crop resilience under environmental stress. The findings offer conceptual and practical advances for developing next-generation nano-enabled strategies in sustainable agriculture.
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