ELECTROCHEMISTRY
·
2025
·
IF 1.7
Hongyu CHEN,Ru TIAN,Jianke LI,Beibei HAN,Guoku LIU,Shiyu YIN,Guiying XU,Kun WANG,Fukuan WANG,Baigang AN,Dongying JU,Weimin ZHOU
TiO2 as a semiconductor photocatalyst has been extensively utilized in the purifications of water and air. However, the wide band gap of TiO2 necessitates its activation by ultraviolet irradiation, when it is utilized as a photocatalyst. To enhance the photocatalyst performance of TiO2, constructing the heterojunction containing TiO2 is considered as a highly effective method. To unfold the actual application, iron metal oxides are firstly utilized to construct the heterojunction of TiO2/α-Fe2O3, and the synthesized TiO2/α-Fe2O3 heterojunction was successfully coated on the surface of coal tar pitch based spherical activated carbons (CTP-SACs). The structures of TiO2/α-Fe2O3/CTP-SACs are verified by the X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and transmission electron microscopy (TEM). The results of UV-vis absorption spectroscopy supports that TiO2/α-Fe2O3/CTP-SACs are promising candidates for the natural light photoncatalysis. It is believed that the exceptional conductivity of CTP-SACs enhances the activity of the photocatalyst, resulting in the TiO2/α-Fe2O3/CTP-SACs exhibiting remarkable sterilization effects under natural light. For instance, the TiO2/α-Fe2O3-60-CTP-SAC shows an excellent sterilization rate (89 %) for the fish culture water under the irradiation of natural light for 20 min. Associating with the excellent liquidity of CTP-SACs, it is considerable that TiO2/α-Fe2O3/CTP-SACs possess the captivating application prospects in a field of the feeding water treatment.
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高影响因子
Journal of Materials Chemistry A
·
2015
·Vol. 3
·期 31
·15905-15912
·
IF 7.443
Xiuwen Wang,Buhe Batter,Ying Xie,Kai Pan,Yongping Liao,Chunmei Lv,Mingxia Li,Siyu Sui,Honggang Fu
We report the synthesis of highly crystalline, small sized, α-NiS nanocrystal inks for the fabrication of a counter electrode for dye-sensitized solar cells. Monodisperse α-NiS nanocrystals (about 7 nm) are obtained via a noninjection, solution-phase chemical synthesis method. During the growth process of α-NiS nanocrystals, the Ni–oleate complex, which is generated in situ from the reaction of nickel chloride and sodium oleate, is decomposed and acts effectively as a growth source in synthesizing monodisperse nanocrystals. By controlling the reaction temperature, the resultant nanocrystal sizes and crystallinity can be well tuned. Compared to conventionally obtained NiS bulk materials, monodisperse α-NiS nanocrystals possess abundant catalytic reaction sites for dye-sensitized solar cells due to their small particle size and high crystallinity. First-principles calculations have been employed for the first time to investigate the adsorption energy of I3− molecules on the (111) surface of α-NiS with equilibrium shape. DSSCs based on monodisperse α-NiS nanocrystal ink with higher crystallinity display a power conversion efficiency of 7.33%, which is comparable to that based on the Pt cathode (7.53%), but significantly higher than that based on the bulk NiS (4.64%) and relatively low-crystalline α-NiS nanocrystals (6.32%). It can be attributed to more reaction catalytic sites due to the surface effect of small α-NiS nanocrystals, and the highest work function level (5.5 eV) that matched the redox shuttle potential. We believe that our method paves a promising way to design and synthesize advanced counter electrode materials for energy harvesting.
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高影响因子
Food Chemistry-X
·
2026
·
IF 9.2
Changdong Lin,Juyuan Luo,Shuo Wang,Cheng Shen,Shucan Zhang,Yongling Liu,Zhibo Song,Yumei Ma,Tao Chen,Yulin Li
Affinity ultrafiltration is widely used for rapid, targeted screening of bioactive natural compounds, but high-abundance components in complex matrices often mask low-abundance yet potent inhibitors, reducing sensitivity. Here, barley seedling extracts were preprocessed via HPLC peak-area clustering before affinity ultrafiltration to identify α-glucosidase inhibitors. This “clustering-prior-to-ultrafiltration” strategy enabled the discovery of four additional low-abundance inhibitors overlooked by direct ultrafiltration. These compounds exhibited stronger inhibitory activity (IC 50 : 217.75–583.35 μg/mL) than the three high-abundance components (IC 50 : 707.05–1044.95 μg/mL). Enzyme kinetics, spectroscopy, molecular docking, and dynamic simulations revealed their binding mechanisms. This approach enhances screening sensitivity and provides a basis for developing functional foods.
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高影响因子
Journal of Cleaner Production
·
2026
·
IF 10.7
Xiaojun Hu,Yufeng Chen,Ziyao Mi,Bo Wang,Yanyan Du,Xinyu Wang,Jingxian Jiang
The remediation of polycyclic aromatic hydrocarbons (PAHs)-contaminated soil has attracted widespread attention these years, ascribed to PAHs are environmental persistent, carcinogenic, teratogenic, and mutagenic, posing serious threats to human beings and ecosystem. Existing advanced oxidation processes (AOPs) for PAHs remediation are always constrained by expensive cost, strong operating conditions dependence and incomplete decomposition. To overcome these limitations, this study proposed an innovative and effective α-Fe 2 O 3 /NaClO catalytic oxidation system to realize reinforced PAHs degradation in industrial site soil. Under the determined optimal mass ratio of α-Fe 2 O 3 /NaClO at 24:1, the combined system demonstrated an increase in PAHs degradation efficiency by 17.9% and 57.3% in comparison with NaClO or α-Fe 2 O 3 employed individually, with the NaClO concentration fixing at 2000 mg/L and initial solution pH setting at 5. The primary reactive free radicals responsible for PAHs degradation were identified as •OH and O 2 · − , while ClO · and Cl 2 · − were evidenced to make contributions as well. In addition, direct electron transfer between α-Fe 2 O 3 and PAHs also participated in PAHs oxidation. Phytotoxicity tests and T.E.S.T. results elucidated the alleviated toxicity of soil remediated by the α-Fe 2 O 3 /NaClO system, further manifesting the practical applicability of this remediation strategy. This research highlighted the great potential of α-Fe 2 O 3 /NaClO catalytic oxidation system in future remediation of PAHs-contaminated soil.
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高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.1
Jinxin Ma,Jieping Zheng,Jiangyao Chen
The rapid, on-site quantification of trivalent chromium (Cr(III)) is crucial for environmental risk assessment, yet conventional analytical methods are severely hampered by their reliance on bulky instrumentation. To address this challenge, we report a portable, dual-mode colorimetric sensing platform centered on the specific interaction between Cr(III) and α-sulfophenylacetic acid-functionalized silver nanoparticles (D-SFA-AgNPs). This interaction triggers the controlled aggregation of nanoparticles, resulting in a distinct yellow-to-gray color change and a significant red-shift in the localized surface plasmon resonance (LSPR) spectrum. To fully leverage this optical response, a low-cost, Arduino-based smart analyzer was engineered, integrating a Red-Green-Blue (RGB) colorimetric mode for rapid screening and a multi-channel spectral mode for trace analysis. Under optimized conditions, the platform achieved a rapid response (< 1 min) with a linear dynamic range of 0.033–100 μg L −1 . The limit of detection (LOD) was determined to be 4.60 μg L −1 , which is significantly lower than the World Health Organization (WHO) guideline for drinking water (50 μg L −1 ). Furthermore, analytical validation in real water samples demonstrated excellent spike recoveries (97.6%–107.6%) and high precision (RSD < 5.9%), showing high consistency with the gold-standard inductively coupled plasma-mass spectrometry (ICP-MS) method. Consequently, by synergizing the Arduino-based open-source hardware with dual-mode sensing, this work provides a cost-effective solution for the point-of-need monitoring of Cr(III), holding great potential for environmental surveillance even in resource-limited areas.
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高影响因子
EUROPEAN POLYMER JOURNAL
·
2019
·
IF 3.621
Xiaocen Lu,Congguang Zheng,Huiqi Zhang
Molecularly imprinted polymers (MIPs) compatible with complex biological samples hold much promise in many bioanalytical and biomedical applications and development of new strategies for obtaining such advanced synthetic receptors is thus of high interest. Herein, a facile and efficient new approach is presented for the preparation of MIP microspheres capable of selectively recognizing small organic analyte in the complex biological sample, which involves the simple surface modification of MIP particles bearing polyethylene glycol (PEG) brushes with α -cyclodextrin ( α -CD). The proof-of-principle was demonstrated by the first synthesis of propranolol-imprinted polymer microspheres bearing PEG brushes of different molecular weights ( M n = 2000 and 5000) via our previously developed reversible addition-fragmentation chain transfer (RAFT) coupling chemistry, their supramolecular inclusion complexation with α -CD, and subsequent chemical crosslinking. The chain length of the surface-grafted PEG brushes showed much influence on the water-compatibility of MIPs. Whereas the MIP particles bearing PEG brushes of M n = 2000 hardly showed specific template bindings in both pure water and pure milk, those bearing PEG brushes of M n = 5000 exhibited moderate specific template bindings in pure water. Nevertheless, the latter MIP particles still failed to show enough specific template bindings in pure milk. The inclusion of α -CD onto PEG brushes proved to largely enhance the surface hydrophilicity of MIPs and lead to their much improved water-compatibility. In particular, the MIP microspheres bearing α -CD-modified PEG brushes of M n = 5000 showed excellent specific template bindings in both pure water and pure milk. The above strategy not only paves the way for efficiently preparing biological sample-compatible MIPs, but also opens the possibility of generating many other advanced biomaterials with high antifouling properties.
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高影响因子
Asian Journal of Pharmaceutical Sciences
·
2016
·Vol. 11
·期 6
·735-743
·
IF 0
Jingwen Guo,Yan Wang,Jing Wang,Xin Zheng,Di Chang,Siling Wang,Tongying Jiang
To achieve GSH-responsive 5-Fluorouridine (5-FU) delivery, a novel family of nanogel drug carriers has been successfully prepared. The new class of PAHy-based nanogels was prepared by the crossing-link reaction of poly- α , β -polyasparthydrazide (PAHy) chains and 3,3′-dithiodipropionic acid (DTDPA) consisting of a redox-responsive chain network. This particle highlights recent efforts in introducing a disulfide bond to drug delivery nanogel by DTDPA, and the increased release properties of complex nanogels produced excellent glutathione (GSH)-sensitivity and significant anti-tumor therapeutic efficacy. The PAHy-based nanogels were characterized by Fourier transform infrared spectroscopy (FT-IR), dynamic light scattering (DLS) (nano-particle size ~200 nm), UV–vis spectrometry, X-ray diffraction (XRD) and differential scanning calorimetric (DSC). PAHy-based nanogels are promising controlled-release carriers for the tumor-targeting delivery of the anticancer agent 5-Fluorouridine.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
·
IF 8.7
Yuanbiao Ma,Xu Liu,Zhewen Deng,Jiaqi Li,Ruoxi Liu,Shanshan Li,Can Zhang,Yutong Chen,Senqiang Zhu,Qi Zhang,Rui Liu,Bo Ma
CMCSMA/F127/TPGS@α-MG hydrogel promotes infected diabetic wound healing. • F127/TPGS micelles improve the aqueous solubility and sustained release of α-MG. • The composite hydrogel disrupts biofilms and achieves 99.6% wound closure. • α-MG modulates PPAR-γ, attenuating inflammation and promoting angiogenesis. Diabetic wounds pose a major clinical challenge owing to their complex microenvironment and persistent inflammation. To address this issue, we engineered a multifunctional, in situ photocrosslinkable composite hydrogel (CMCSMA/F127/TPGS@α-MG) to promote wound healing. To overcome the hydrophobicity of the antimicrobial agent α-mangostin (α-MG), it was first encapsulated in F127/TPGS nanomicelles. These micelles were then integrated into a methacrylated carboxymethyl chitosan (CMCSMA) matrix, enabling rapid conformal gelation upon 405 nm light irradiation. The resulting hydrogel exhibited a biphasic sustained-release profile, excellent biocompatibility, and potent contact-killing and anti-biofilm activities against Staphylococcus aureus ( S. aureus ). In an S. aureus -infected diabetic wound model, the hydrogel significantly accelerated wound closure, achieving 99.6% closure by day 14, and facilitated high-quality tissue regeneration characterized by complete re-epithelialization and orderly collagen deposition. Furthermore, an integrated approach combining network pharmacology, molecular docking, molecular dynamics simulations, and experimental validation revealed that the therapeutic efficacy of sustained local α-MG delivery involves the modulation of the PPAR-γ pathway. This regulatory process suppresses the NF-κB/COX-2 inflammatory axis and upregulates pro-angiogenic markers, including VEGF, CD31, and α-SMA. Collectively, this dual-action platform, which synergizes physical barrier protection with targeted molecular modulation, represents a promising translational strategy for refractory diabetic wounds. Schematic illustration of the preparation process and functional attributes of the in situ forming CMCSMA/F127/TPGS@α-MG hydrogel. Download: Download high-res image (67KB) Download: Download full-size image
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高影响因子
CARBOHYDRATE POLYMERS
·
2026
·
IF 13.2
Hanghang Zhang,Longzhu Bao,Wei Wang,Manli Yu,Chong Cao,Pengyue Zhao,Qiliang Huang,Lidong Cao
The novel plant-derived biopesticide erucamide (Eru) holds promise for controlling plant bacterial diseases, yet its poor water solubility and formulation instability limit practical application. Here, supramolecular aggregate particles in aqueous solution via host-guest recognition between α-cyclodextrin (α-CD) and Eru were constructed. These particles serve as the sole stabilizer to emulsify a carvacrol (Car) oil phase pre-loaded with additional Eru, yielding a surfactant-free, all-natural Pickering emulsion (PE). Compared with a conventional suspension concentrate (SC), the PE exhibits superior wettability and adhesion on superhydrophobic rice leaves, improving pesticide utilization efficiency. In addition, the PE exhibited potent inhibitory activity against the mycelial growth of nine fungal pathogens, with EC 50 values ranging from 8.2 to 37.2 μg/mL. This antifungal activity is closely associated with the incorporated Car, as the SC formulation without Car showed no inhibition against these strains under the same conditions. Moreover, in a 14-day greenhouse trial on rice seedlings, the PE treatment resulted in a 17.2% increase in root length, 5.6% increase in shoot length, and 17.8% increase in aboveground fresh weight relative to the untreated control. This study provides a distinctive paradigm for developing eco-friendly multifunctional agrochemical formulations, particularly for hydrophobic, long-alkyl-chain active ingredients, to overcome solubility and utilization challenges. Download: Download high-res image (113KB) Download: Download full-size image
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Atmosphere
·
2026
·Vol. 17
·期 5
·451
·
IF 2.6
Hao Jiang,Quanfu He,Bin Jiang,Xiang Ding
Cross-reactions between peroxy radicals (RO2) derived from different volatile organic compound (VOC) precursors have been proposed as an important pathway during atmospheric oxidation. However, direct molecular evidence has been limited. In this study, α-pinene and fully deuterated toluene (d8-toluene) were oxidized separately and as a mixture in a potential aerosol mass (PAM) flow reactor, and the resulting secondary organic aerosol (SOA) was characterized by a high-resolution mass spectrometer (ESI FT-ICR-MS). A constrained chemical mass balance (CMB) model attributed 82.9% of the mixed-SOA signal to single-precursor sources (66.5% α-pinene, 16.4% d8-toluene), leaving a 17.1% signal-based residual fraction unexplained by linear mixing. Among 2450 residual molecular formulas exclusive to the mixed-SOA, 1858 were identified as cross-reaction candidates, with carbon, oxygen, and double bond equivalents (DBE) distributions consistent with RO2-RO2cross-reactions between toluene- and α-pinene-derived fragments. We also identified representative monomer-dimer pairs, where one monomer corresponded to a known α-pinene oxidation product, while the other matched a primary oxidation product of d8-toluene oxidation based on the Master Chemical Mechanism (MCM), providing strong molecular-level evidence for RO2-RO2cross-reactions. Our findings demonstrate that the mixed VOCs generate unique SOA products that extend beyond simple additive chemistry, with implications for SOA yield parameterizations and chemical transport models.
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高影响因子
Food Bioscience
·
2026
·
IF 6.2
Yongfu Li,Xiaoqiang Chen,Jinrong Huang,Feng Shi
Gastrodia elata is an edible plant whose phenolic compounds show α-glucosidase inhibitory activity. Through screening, it was found that 4-hydroxybenzyl alcohol (HBA) is the most potent inhibitor (IC 50 = 0.0406 mg/mL). However, HBA occurs at very low levels in native G. elata , making it difficult to acquire sufficient active components via routine approaches. Different from conventional organic solvent extraction and microbial fermentation, the β-glucosidase-catalyzed strategy developed here has the advantages of short processing time, mild reaction conditions and environmental friendliness. Compared with water extraction, this method increased HBA content by 9.76 fold and improved α-glucosidase inhibitory activity by 5.31 fold. Enzymolysis conditions were optimized via response surface methodology at 51.5°C, 6 U/mL and 4.7 h, yielding 832 μg/mL HBA with an inhibition rate of 71.4%. Pearson correlation confirmed HBA as an important contributor to the bioactivity (r = 0.6669). Mechanistic analyses via kinetics, spectroscopy, molecular docking, and 100 ns molecular dynamics simulations revealed HBA acts as a non-competitive inhibitor binding to the allosteric site at Ser236, Asn317, and His423. The optimized extract (5% v/v, 322 μM HBA) significantly promoted glucose consumption and glycogen synthesis in insulin-resistant HepG2 cells without cytotoxicity. It also dose-dependently reduced glucose, triglyceride, and total cholesterol in high-glucose-stimulated zebrafish larvae. This efficient catalytic approach achieves high HBA enrichment and clarifies the underlying inhibitory mechanism, supporting G. elata extract as a promising functional food for glycemic and lipid regulation.
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高影响因子
Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 3
·122374
·
IF 7.5
Feng Chen,Xiang Xia,Wei Chen,Wei Liu,Xinxin Liao,Lei Xiong,Yanqiao Jin
Refining lignin and its derivatives into biofuels and fine chemicals via catalytic transfer hydrogenation (CTH) has gained significant attention for its potential in utilizing renewable resources and reducing fossil fuel dependence. Herein, a series of bimetallic Cu-Co catalysts with varying metal ratios are synthesized via a facile hydrothermal method and successfully applied in the efficient CTH of the α-O−4 model compound benzyl phenyl ether (BPE) and corncob lignin. Cu 0.5 Co 1 @CN has the best performance among catalysts with different CuCo ratios due to the formation of the CuCo 2 O 4 phase which provides more acid sites and hydrogen adsorption/desorption sites. Under the reaction conditions of 190 °C in isopropanol, the Cu 0.5 Co 1 @CN catalyst achieves the complete conversion of BPE to cyclohexanol and toluene, and demonstrates excellent CTH performance towards other α-O−4 and β-O−4 model compounds. This catalyst simultaneously enables the demethoxylation and hydrogenation of phenolic compounds like guaiacol. Furthermore, Cu 0.5 Co 1 @CN efficiently converts corncob lignin, producing a high proportion of phenolic compounds in the resulting liquid (88.26%), while preventing the aromatic hydrocarbons from being hydrogenated. Overall, this work provides a novel and effective strategy for transforming lignin into high-value products.
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