ANALYTICA CHIMICA ACTA
·
2016
·
IF 4.712
Hongliang Tan,Gonge Tang,Chanjiao Ma,Qian Li
In this work, we developed a simple and sensitive method for the detection of cysteine (Cys) by employing terbium ion (Tb 3+ )-promoted G-qudraplex (G4/Tb) as a luminescent probe, which is based on Ag + -mediated conformational change of G4/Tb. Due to Ag + is able to compete with Tb 3+ to bind guanine at G4, the presence of Ag + can lead to the formation of G4/Tb–Ag + complex and disrupt the structure of G4/Tb. Meanwhile, the binding of Ag + with G4/Tb will also cause the alteration of the excited state of G4 and more efficient energy transfer from G4 to Tb 3+ , enhancing the luminescence of G4/Tb. However, upon the addition of Cys, Ag + will be released from G4/Tb–Ag + complex because of the high affinity of Cys to Ag + . This results in the re-formation of the conformation of G4/Tb and the decrease of the luminescence of G4/Tb. So, Ag + -enhanced luminescence of G4/Tb is associated with its conformational transformation. As a luminescent probe for Cys, G4/Tb not only shows excellent selectivity and sensitivity with a detection limit of 20 nM, but also possesses the features of simple preparation, easy reproducibility, and eliminating the interferences from background fluorescence. We envision that the presented strategy might provide new insight into the biosensing applications of lanthanide complex.
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DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 8
·1-9
·
IF 6.232
Wei Yu-ping,Zhang Yi-wen,Chen Jing-Shuai,Mao Chang-jie,Jin Bao-Kang
An ultrasensitive electrochemiluminescence biosensor was established based on the Zn-MOF/GO nanocomposite. Ag(I)-embedded DNA complexes were used as a signal amplification reagent. In this work, 5,10,15,20-tetrakis(4-carboxyphenyl)porphyrin (TCPP) and Zn 2+ were integrated into a porphyrin paddlewheel framework (Zn-MOF) by a hydrothermal method. The synthesized Zn-MOF material has electrochemiluminescence property, and the luminescence intensity is improved after being composited with graphene oxide (GO). Based on the composite material, we constructed an ultrasensitive ECL biosensor for the p53 antibody detection. The composite material acted as an admirable substrate and then loaded plenty of p53 antigens to recognize the target (p53 antibody) accurately. Because of the bridging effect of streptavidin and biotin-conjugated goat anti-rabbit IgG (bio-ab2), the rich-C DNA with positive correlation with the target was modified on the electrode and then captured the co-reactant accelerator Ag + to amplify the signal. Therefore, the ECL biosensor response increases with increasing p53 antibody concentration. In the range 0.1 fg/mL–0.01 ng/mL, the response signal of the biosensor has a good linear relationship with the p53 antibody concentration. The detection limit is 0.03 fg/mL (S/ N = 3). Impressively, the biosensor not only featured high sensitivity, good stability, and excellent specificity for the detection of p53 antibody, but also provides a new way for early detection of cancer.
Schematic representation of the electrochemiluminescence sensor based on a Zn-MOF/GO nanocomposite, which can be applied to the determination of p53 antibody.
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DOI
PubMed
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2025
·Vol. 109
·期 1
·e70360
·
IF 3.8
Zhang Xiangzhao,Zhang Yinuo,Wang Chen,Guo Qinhan,Liu Guiwu,Qiao Guanjun
This study investigates the effect of SiC pre-oxidation on the air reactive wetting and brazing behavior of Ag–Nb 2 O 5 fillers. An obvious SiO 2 layer induced by the pre-oxidation can improve the wettability of the Ag–Nb 2 O 5 /SiC system as the contact angle decreases from ∼75° to ∼25° with increasing Nb 2 O 5 content, accompanied by localized AgNbO 3 formation at the interface and the triple line. Moreover, the Nb 2 O 5 addition promotes a progressive growth of AgNbO 3 , transforming the interfacial structure from Ag/SiO 2 /SiC to Ag/AgNbO 3 /SiO 2 /SiC. An optimal Nb 2 O 5 content effectively reduces the direct Ag/SiO 2 contact while avoiding excessive AgNbO 3 formation and associated thermal stresses, resulting in a maximum shear strength at 4% Nb 2 O 5 . First-principles calculations demonstrate that the AgNbO 3 /SiO 2 interface exhibits a higher bonding strength than the Ag/SiO 2 interface, showing a strong interfacial charge transfer between AgNbO 3 and SiO 2 , which is consistent with enhanced mechanical performance. The insights gained from SiC pre-oxidation offer a potential pathway for advancing the air brazing of other non-oxide ceramic systems.
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产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2019
·
IF 5.155
Yu-Zhuang Gao,Tian-Xiao Chang,Yi-Xian Wu
Biomass sodium alginate (SA) and biomass-derived ether tetrahydrofuran (THF) have drawn considerable attention due to their sustainability and bio-renewability. In this paper, the novel acylated sodium alginate- g -polytetrahydrofuran graft copolymers (ASA- g -PTHF) with various PTHF branches ( M n,PTHF = 600–4800 g/mol, G N = 3–20 per 1000 SA monosaccharide) could be successfully synthesized by combination of THF living cationic ring-opening polymerization with grafting-onto method. The microphase separation of ASA- g -PTHF graft copolymer formed via self-assembly from two kinds of segments in backbone and side chains and was emphasized by thermal annealing, leading to a remarkable increase in water contact angle on polymer surface even by 38.4°. The hydrophilicity and crystallization behavior of ASA- g -PTHF can be decreased with increasing M n,PTHF and G N , which confine the crystallization of graft copolymer. ASA- g -PTHF microspheres (~1 μm) loaded with ibuprofen shows pH sensitivity and reach 100% of drug-release at pH = 7.4 within 30 h. ASA- g -PTHF exhibits resistance to bovine serum albumin adsorption and its composite with small-scaled silver nanoparticles (Ag-NPs, <2.6 wt%, 5–15 nm) generated in - situ behaves good antibacterial performance against E. coli and S. aureus . The ASA- g -PTHF would contribute to the better utilization of biomass and has promising for biomedical applications.
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高影响因子
APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Shixin Huang,Wei Liu,Zhicheng Wen,Chunjin Hang,Rong An,Yongfeng Li,Yanhong Tian
The design of a sensing material for detecting isopropanol gas with low operating temperature is extremely important for miniaturization and wearability of gas sensors. Herein, a novel gas sensor based on SnO 2 -Carbon nanosphere heterojunctions decorated with Ag nanoparticles (SCA) was fabricated and its gas sensing performance was evaluated and compared systematically. The measurement results indicated that the sensing performance was influenced by the ratio of Sn/C and the length of Ag plating, and the SCA sensor provided the best response. For 100 ppm isopropanol at 100 °C, the SCA sensor exhibited a response value of 50.51, a response time of 7 s and a recovery time of 60 s. The enhanced sensing performance and reduced operating temperature of the SCA could be attributed to the synergistic effect of the SnO 2 -Carbon nanosphere heterojunctions and the significant catalytic performance of the decorated Ag nanoparticles. In addition, the density functional theory calculation method based on the first-principles theory was used to study the adsorption performance and electronic behavior, as well as the influence of Ag decoration on SnO 2 for isopropanol detection. The calculated results were consistent with the experimental results.
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高影响因子
Materials Today Communications
·
2024
·
IF 3.7
Wenbin Li,Zhijian Zhou,Zhili Chen,Li Chen,Jin Tang,Lizhao Zhang
In this study, a new adsorbent denoted as nAg/nZVI/AC was developed using activated carbon (AC) loaded with nanosized zero-valent iron (nZVI) and nanosilver (nAg). Then, the adsorption and degradation of tetracycline hydrochloride (TCH) in aqueous solutions using nAg/nZVI/AC was examined. At pH 3.8, the adsorbed amount of TCH on nAg/nZVI/AC was 191.18 mg/g, which is 78.95 mg/g higher than that adsorbed on the pristine AC support. The adsorption process could be explained adequately using the Freundlich (R 2 = 0.9641) and pseudo-second-order kinetic models (R 2 = 0.9967). Thermodynamic analyses revealed that TCH removal is a spontaneous chemisorption-dominated process. Free-radical-quenching experiments and electron paramagnetic resonance spectroscopic studies revealed that hydroxyl (·OH) and superoxide (·O 2 − ) radicals are the main species involved in the degradation of TCH. Finally, the intermediates generated during the degradation were examined using liquid chromatography-mass spectrometry, and possible deterioration pathways are proposed.
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DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2023
·
IF 6.2
Yucheng Li,Kuan Ren,Shuai Cheng,Yahua Hu,Xuechun Yang,Shutong Hao,Shenye Liu,Naixin Li,Zhan Xu,He Feng,Xing Zhang,Tao Xu,Xiaoyan Zhou,Yuji Wu,Zhenghua Yang,Pin Yang,Jianjun Dong,Yulong Li,Huiyue Wei,Xiaoshi Peng,Xiangming Liu,Zanyang Guan,Zhiwen Yang,Jin Li,Yunsong Dong,Dong Yang,Tao Yi,Jiamin Yang,Yongkun Ding,Zhixiang Sun,Xiaolin Liu,Mu Gu,Jingtai Zhao,Guang Yang,Qianli Li
The ultrastable encrypted storage of X-ray image with quantitative and ultrahigh-spatial resolution are crucial for a wide range of applications in radiation imaging, and it can be achieved by using the radio-photoluminescence (RPL) material, Ag-doped phosphate glass (Ag-PG), which was fabricated via the melt-quenching method. Under X-ray irradiation, Ag-PG produces a luminescence center, obvious 650 nm emission peak, which can be repeatedly excited by ultraviolet light without intensity attenuation. Quantitative X-ray image storage was realized based on the linear relationship between RPL intensity and X-ray irradiation time. X-ray image with a submicron spatial resolution of 0.7 µm was achieved, which could be stably stored without attenuation for more than 300 days. This submicron level X-ray image can be written into the Ag-PG as an encrypted information, and can only be visualized by an ultraviolet light. Additionally, heat treatment (400 °C for 2 h) could eliminate the influence of X-ray radiation on the Ag-PG, and restore the state of the Ag-PG before X-ray irradiation, which allows the recyclability and reusability of the Ag-PG. This research is of great significance for promoting the encrypted storage of X-ray images based on Ag-PG or other RPL materials.
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高影响因子
ARCHIVES OF ORAL BIOLOGY
·
2019
·
IF 1.663
Qiaomu Huang,Shilei Wang,Yujun Sun,Cheng Shi,Hao Yang,Zhong Lu
Objective Streptococcus mutans ( S. mutans ), the main pathogen of dental caries, could be well killed by Ag/ZnO nanocomposite. However, effects on virulence factors remain to be elucidated. This study investigated effects of Ag/ZnO at sub-minimum inhibitory concentrations (sub-MICs) on virulence factors of S. mutans and related genes expressions. Design Effects of Ag/ZnO on the growth of S. mutans was investigated by growth curves and MTT staining method. The influence of Ag/ZnO at sub-MICs on biofilm formation was measured by the crystal violet staining method and observed by a scanning electron microscopy. Adherence, cell-surface hydrophobicity, acidogenicity and extracellular polysaccharides (EPS) of S. mutans after treatment by Ag/ZnO at sub-MICs were also investigated. Virulence factors related genes expressions after treated by Ag/ZnO at 1/2 MIC was conducted by the quantitative real-time PCR (qRT-PCR) method. Results Sub-MICs of Ag/ZnO exhibited a dose-dependent inhibition on the virulence factors of S. mutans . Specially, Ag/ZnO at 1/2 MIC decreased 69.00 % biofilm formation, 31.78 % sucrose-independent and 48.08 % sucrose-dependent adherence, 69.44 % cell-surface hydrophobicity and 72.45 % water-soluble and 90.60 % water-insoluble EPS. Furthermore, the expression of virulence factors related genes was significantly suppressed by Ag/ZnO at 1/2 MIC. Conclusions Ag/ZnO at sub-MICs inhibited multiple virulence factors of S. mutans through downregulating the related genes. Ag/ZnO nanocomposite could be used for prevention of dental caries at low dosage.
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高影响因子
npj Flexible Electronics
·
2024
·Vol. 8
·期 1
·1-12
·
IF 12.3
Shi Wei,Li Hui,Xu Chengsheng,Wu Gaoyi,Chen Jing,Zhang Jinyong,Liang Lixin,Wu Qingyang,Liang Yongsheng,Li Guanglin,Tang Wei
Flexible sensors are promising candidates in personalized healthcare, while desired sensors that allow implantation for biomedical applications with optimal sensing and favorable biological properties remain challenges. Here, a multifunctional hydrogel sensor was developed with gallic acid-modified chitosan (CSGA) and 3-carboxyphenylboronic acid-modified chitosan (CSPBA) by encapsulating Ag-decorated polydopamine (Ag@PDA) nanoparticles, namely Ag@PDA-(CSPBA/CSGA). The optimized hydrogel sensor showed desired sensitivity (gauge factor = 2.49), a rapid response/recovery time of 263 ms and good durability. Due to the presence of abundant reactive groups within Ag@PDA-(CSPBA/CSGA), the hydrogel sensor exhibited a comprehensive performance of self-healing, tissue adhesiveness, antioxidative activity, and antibacterial effects against Escherichia coli (92.76%) and Staphylococcus aureus (98.08%). Moreover, the hydrogel sensor could be utilized as a wound dressing, facilitating accelerated wound closure and tissue regeneration. Both subtle activities and large-scale movements could be monitored and distinguished by the hydrogel sensor. This study provides a promising epidermal sensor that offers multifunctionality for health monitoring and wound management.
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高影响因子
CHEMISTRY-A EUROPEAN JOURNAL
·
2019
·Vol. 25
·期 36
·8560-8569
·
IF 5.16
Xingwang Lan,Yiming Li,Cheng Du,Tiantian She,Qing Li,Guoyi Bai
Graphical Carboxylation catalysts : Porous carbon nitride frameworks with uniform and rich nitrogen dopants and abundant porosity were successfully fabricated through the carbonization of the covalent triazine frameworks at different pyrolysis temperatures, and used as supports to immobilize and stabilize Ag nanoparticles for catalytic CO 2 conversion (see picture). Porous carbon nitride frameworks (PCNFs) with uniform and rich nitrogen dopants and abundant porosity were successfully fabricated through the direct carbonization of the covalent triazine frameworks (CTFs) at different pyrolysis temperatures and used as supports to anchor and stabilize Ag nanoparticles (NPs) for catalytic CO 2 conversion. Importantly, the pyrolysis temperature plays a crucial role in the properties of porous carbon nitride frameworks. The material carbonized at 700 °C showed the highest surface area and micro- and mesoporous structure with a certain interlayer distance. Taking advantage of their unique surface characteristics, PCNF-supported Ag NP catalysts (Ag/PCNF- T , T =pyrolysis temperature) were prepared by a simple chemical method. A series of characterizations revealed that Ag NPs are embedded in the porous carbon nitride frameworks and confined to a relatively small size with high dispersion owing to the assistance of the abundant surface groups and porous structures. The as-obtained Ag/PCNF- T catalysts, especially Ag/PCNF-700, showed excellent catalytic activity, selectivity, and stability for the carboxylation of CO 2 with terminal alkynes under mild conditions. This can be due to the existence of abundant nitrogen atoms and diverse porosity, which resulted in highly efficient catalytic activity and stability.
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DOI
高影响因子
MICROCHIMICA ACTA
·
2023
·Vol. 191
·期 1
·1-10
·
IF 5.7
Wang Zedong,Zhang Liang,Sun Lian,Bao Siqi,Liu Dajun,Li Hongji,Liu Yuming
Silver nanocubes monolayer-modified polydimethylsiloxane (Ag NC/PDMS) flexible SERS substrates have been prepared by a three-phase interface self-assembly procedure. The combination of this method with membrane technology brings nanoparticles in close proximity, densely, and regularly arranged in monolayers over a large area, leading to excellent SERS properties. Considering the complexity of practical detection, molecular imprinted polymers (MIPs) were anchored on the surface of SERS substrate and applied to selective detection of microcystin-LR (MC-LR). It is worth mentioning that the SERS imprinted membranes (AP-MIMs) were still clearly detected at a concentration of 0.1 µg·L −1 of MC-LR in drinking water, and the detection limit was as low as 0.0067 µg·L −1 . The substrate exhibited excellent uniformity with a relative standard deviation (RSD) of 6.1%. In the presence of interference molecules, AP-MIMs exhibited excellent selectivity for MC-LR. Furthermore, in the spiking and recovery tests of practical lake water samples, the method showed excellent recoveries ranging from 96.47 to 105.31%. It has been demonstrated that the prepared AP-MIMs can be applied to sensitive and specific detection of trace amounts of MC-LR in drinking water. Graphical
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高影响因子
Micro & Nano Letters
·
2021
·Vol. 16
·期 4
·257-262
·
IF 1.102
Xiao Wang,Mei Wu,Chulei Zhao,Xiaochen Liao,Mengmeng Zhang,Lisha Mei,XiuWen Qiao,Chenglin Hong
Using Ag-CoFe 2 O 4 -GO nanocomposite as biosensor interface, a novel unlabelled electrochemical immunosensor was designed to detect tumour marker carcinoembryonic antigen. Here, Ag-CoFe2O4-GO was synthesized by one-pot method as an immunological probe. They have the following advantages: (1) Silver nanoparticles have a strong redox capacity under applied voltage and good biocompatibility, so they can bind more antibodies; (2) GO has a large specific surface area, which can load more Ag NPs and CoFe 2 O 4 nanoparticles, and has excellent conductivity; (3) CoFe 2 O 4 is widely favoured by researchers due to its advantages such as low production cost and simple preparation process, The prepared Ag-CoFe 2 O 4 -GO nanocomposite can amplify the electrochemical signal; (4) The presence of GO can effectively prevent the agglomeration of Ag NPs nanoparticles and CoFe 2 O 4 nanoparticles, promote the formation of electron transfer network, and contribute to the electron transfer of sensors. Under optimal condition, the current signal and the concentration of carcinoembryonic antigen were linear in the range of 1 pg mL < sp > −1 < /sp > ∼ 80 ng mL < sp > −1 < /sp , > and the detection limit was 0.3 pg mL < sp > −1 < /sp > (S/N = 3). Under certain conditions, the manufactured immunosensor has good reproducibility, selectivity and excellent stability. Thus it has certain clinical value for the detection of carcinoembryonic antigen.
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高影响因子
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