APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Gangrong Chen,Yongtao Yuan,Ming Lang,Zeping Lv,Weilin Ma,Naiting Gu,Hong Liu,Jingzhong Fang,Haibin Zhang,Yuntao Cheng
Herein, we report a facile and straightforward synthetic strategy for preparing flexible NH 3 sensors with high performance and application prospects. Interestingly, core–shell Au@SiO 2 nanocrystals (NCs) doped polyaniline (PANI) were innovatively employed as the sensitive material and the NH 3 sensors were constructed via a simple droplet-evaporation self-assembly process on the polyimide substrates. Experimental results show that the well-designed NH 3 sensor with ∼ 20 wt% of Au@SiO 2 NCs doping PANI exhibited high sensitivity, flexibility and combined reproducibility at room temperature: the device’s detection limit of NH 3 reached a 10 ppb level; the device’s concentration deviation induced by large-angle and cycled bending could be kept within 0.6 ppm, and the maximum response variation was less than 2.7% through 30 days of monitoring; Additionally, the designed NH 3 sensor does have insusceptibility to the ambient relative humidity (from 48% to 66%). Indeed the sensing mechanism of our NH 3 sensor was discussed from the Au@SiO 2 NCs doped PANI structure, the crucial role of abundant hydroxyl (–OH) functional groups, and the catalytic activity of Au NPs. Overall, this study demonstrates an alternative and effective pathway to fabricate high-performance and applicable NH 3 sensors, which may be conducive to further application for environmental NH 3 detection and human kidney disease diagnosis.
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FOOD CHEMISTRY
·
2022
·
IF 9.231
Cheng Zhao,Jiabin Shen,Shanshan Xu,Jing Wei,Haiquan Liu,Siqi Xie,Yingjie Pan,Yong Zhao,Yongheng Zhu
Trimethylamine (TMA) is an organic amine gas used as an important index to assess the seafood freshness. In this work, an ultra-efficient trimethylamine gas sensor was constructed by ultrasonic treatment loading of Au nanoparticles (∼4 nm) on WO 3 nanosheets prepared by solvothermal self-assembly method. The response of the sensor to 25 ppm TMA was as high as 217.72 (R air /R gas ) at 300 ℃. In addition, the Au/WO 3 nanosheets sensor exhibited rapid response-recovery time (8 s/6 s), low detection limit (0.5 ppm), and high selective detection of TMA. Moreover, the composition of volatiles produced by decay of Larimichthys crocea (0–15 days) was examined, which proved that the detection of TMA by the Au/WO 3 sensor can evaluate the freshness of Larimichthys crocea . Such a magnificent gas sensing performance reveals that the Au/WO 3 sensor has remarkable application potential in rapid and non-destructive seafood freshness assessment on the spot.
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高影响因子
Food Chemistry-X
·
2022
·
IF 6.443
Chong Chen,Hong Lei,Nan Liu,Hui Yan
This paper reports a portable fluorescence resonance energy transfer (FRET) aptasensor for ampicillin (Amp) detection using upconversion particles (UCNPs) as energy donors and Au nanoparticles (AuNPs) as energy acceptors. The optimal parameters of the detection system were investigated. Under the optimal conditions, it had a good linear relationship between the fluorescence intensities and Amp concentrations, a high coefficient of determination (R 2 ) of 0.9939, a wide detection range of 10–100 ng/mL, and a low limit of detection (LOD) of 3.9 ng/mL; meanwhile, the aptasensor had high selectivity for Amp against the interference of other antibiotics, and had good recovery and repeatability. Also, its detection performance had been successfully validated by milk samples. Therefore, the developed aptasensor based on FRET between UCNPs and AuNPs has a good prospect for Amp on-site detection in milk with a portable upconversion detection instrument.
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高影响因子
ACS Applied Nano Materials
·
2022
·
IF 6.14
Jie Yang,Tianran Wang,Weiye Gao,Chushu Zhu,Xuyuan Yin,Peitao Dong,Xuezhong Wu
Surface acoustic wave (SAW) devices are extensively used to detect various gaseous chemicals, owing to their wireless passive potential and single-signal display. However, the sensitivity, selectivity, and long response time of the sensitive layers limit their use in detecting explosive gases. In this study, we developed a 2,4,6-trinitrotoluene (TNT) gas sensor based on the SAW device with GO/PDEA/AuNR/PATP nanocomposites. The GO/PDEA/AuNR/PATP-SAW sensor recorded a considerable negative frequency shift (−70.67 kHz) in detecting 80 ppm TNT at 25 °C/20 RH %, thus enabling the detection of 40 ppb to 80 ppm TNT with the limit of detection as low as 40 ppb (−3.02 kHz). Short response/recovery time (40 ppb: 6.2/11.8 s) with good cycling stability and selectivity were achieved. The high performance of the GO/PDEA/AuNR/PATP-SAW sensor is attributed to its large specific surface area, roughness, and porosity. The oxygen-containing and electron-rich amino groups of the GO/PDEA/AuNR/PATP provide many active sites for adsorbing TNT gas. The primary sensing mechanism is the mass and electrical load of the nanocomposite in TNT gas. It has an optimum thickness of 380 nm and room temperature as the optimum operating temperature. Therefore, this study would serve as a good basis for the research and development of next-generation acoustic gas-phase explosive sensors.
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Nanomaterials
·
2022
·Vol. 12
·期 14
·2359
·
IF 5.719
Hao Fu,Weiwei Liu,Junqing Li,Wenguang Wu,Qian Zhao,Haoming Bao,Le Zhou,Shuyi Zhu,Jinglin Kong,Hongwen Zhang,Weiping Cai
Surface-enhanced Raman scattering (SERS) provides an unprecedented opportunity for fingerprinting identification and trace-level detection in chemistry, biomedicine, materials, and so on. Although great efforts have been devoted to fabricating sensitive plasmonic nanomaterials, it is still challenging to batch-produce a SERS substrate with high sensitivity, good reproducibility, and perfect recyclability. Here, we describe a facile fabrication of three-dimensional (3D) hierarchical Au/CuS nanocomposites, in which high-density Au nanotips enable highly SERS-active sensing, and the well-defined microflower (MF) geometry produces perfect signal reproducibility (RSD < 5%) for large laser spot excitations (>50 μm2), which is particularly suitable for practical on-site detection with a handheld Raman spectrometer. In addition, a self-cleaning ability of this Au/CuS Schottky junction photocatalyst under sunlight irradiation allows complete removal of the adsorbed analytes, realizing perfect regeneration of the SERS substrates over many cycles. The mass-production, ultra-sensitive, high-reproducibility, and fast-recyclability features of hierarchical Au/CuS MFs greatly facilitate cost-effective and field SERS detection of trace analytes in practice.Keywords:Au/CuS hybrids;high-density nanotips;SERS;signal reproducible;substrate recyclable
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Chemosensors
·
2022
·Vol. 10
·期 9
·373
·
IF 4.229
Junfang Hao,Min He,Bin Liu,Jianhui Yang
The preparation and self-assembling of monodisperse gold nanoparticles (Au NPs) is of great significance for its SERS application. According to the oleylamine-reduced method, oleylamine (OAm) serves as the reducing agent and stabilizing agent, and the effects of different reaction parameters such as solvent and temperature on the size and dispersity of Au NPs have been evaluated. The Au NPs synthesized with toluene as the solvent have the best dispersity and narrowest particle size distribution with adjustable sizes. The particle size gradually increases with the increase in reaction temperature. The highly ordered self-assembly film of Au NPs was employed as surface-enhanced Raman scattering (SERS) substrate for the probing molecule of rhodamine 6G. The Au substrate exhibits excellent spatial uniformity and SERS reproducibility, which indicates its practicability as a substrate. This study provides a simple synthesis strategy of highly ordered monodispersed Au NPs, which can serve as a SERS substrate with excellent spatial uniformity and SERS re-producibility.Keywords:gold nanoparticles;solvent effect;monodispersity;surface-enhanced Raman scattering (SERS)
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ELECTROCHIMICA ACTA
·
2022
·
IF 7.336
Qianqing Wu,Zhenhui Li,Qianwei Liang,Rongkai Ye,Shuzhou Guo,Xiaobing Zeng,Jianqiang Hu,Aiqing Li
MicroRNAs (miRNAs) are considered as potential biomarkers for early diagnosis and prognostic assessment of diabetic nephropathy. In this work, an electrochemical biosensor for ultrasensitive detection of miRNA-377 was constructed based on MXene-Au nanocomposites and G-quadruplex nano-amplification strategy. As a promising nanocarrier, taking advantage of leveraging synergistic effects between Au nanoparticles (AuNPs) and MXene nanosheet, MXene-Au nanocomposites exhibited excellent electronic conductivity and provided massive active sites for DNA capture probe immobilization by Au-S bonds. AuNPs modified with Guanine-rich sequence DNA detection probes were designed as signal amplification nano-labels. Specifically, by inducing the transition of Guanine-rich detection probes to G-quadruplex, the strong affinity interaction between methylene blue and G-quadruplex could not only reflect trace concentration information of miRNA-377, but also lead to the further enhancement of electrochemical signal (2.7-fold). As a result, this newly designed biosensor exhibited superior sensing performance with a wide linear range from 10 aM to 100 pM and the limit of detection was as low as 1.35 aM. Compared with biosensors based on other nanocomposites and reported miRNA-377 biosensors, the proposed sensing platform did not require any thermal cycling or reverse transcription process, meeting the miRNA sensing requirements of convenient, sensitive, specific and stable. Furthermore, the as-constructed biosensor also displayed good selectivity, which was applied to accurate detection of miRNA-377 in human serum samples with satisfactory sensitivity, suggesting the biosensor system has promising applications in biological researches and early clinical diagnosis for diabetic nephropathy.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2022
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IF 4.831
Jian Zhu,Li-na Meng,Xin Li,Guo-jun Weng,Jian-jun Li,Jun-wu Zhao
In this paper, the fluorescence quenching characteristics of Au-Ag-Pt core–shell nanorods have been studied. Due to nonradiative energy transformation, the fluorescence emission intensity of bovine serum albumin (BSA) could be greatly quenched. It has been found that the quenching effect of Au-Ag-Pt core–shell nanorods could be optimized by adjusting the concentration of chloroplatinic acid. Based on the fluorescence quenching properties of Au-Ag-Pt core–shell nanorods, Au-Ag-Pt trimetal fluorescence quenching nanoprobe has been prepared, and the specificity of alpha-fetoprotein (AFP) detection has also been realized. In order to guarantee the sensing specificity, the surface modification including carboxyl replacement, carboxyl activation and antibody connection have been performed on Au-Ag-Pt core–shell nanorods. By using the principle of specific combination of antigen and antibody, the specific detection of AFP has been realized with a lower detection limit of 4.0 pg/mL, and the linear detection range spans a scope from 0.03 to 0.5 ng/mL. Interference experiments and the actual samples detection results show that the Au-Ag-Pt trimetal core–shell nanorod probes have good anti-interference and repeatability.
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ACS Omega
·
2021
·
IF 3.512
Linzhi Li,Xing Liu,Saijun He,Hongmei Cao,Benchao Su,Tianzeng Huang,Qi Chen,Minghuan Liu,Da-Peng Yang
A novel ultrasensitive electrochemiluminescence (ECL) immunoassay based on Au/CaCO3 was proposed for detecting ochratoxin A (OTA) in coffee. Au/CaCO3 nanocomposites synthesized using waste eggshells as the template with a large surface area and excellent electrochemical properties were applied for immobilizing a large amount of Ru(bpy)32+ and conjugating a high-affinity nanobody (prepared by the phage display technique). Coupling of the Au/CaCO3 nanocomposites and nanobody technologies provided an ultrasensitive and highly selective ECL immunosensor for OTA detection in the range of 10 pg/mL–100 ng/mL with a low detection limit of 5.7 pg/mL. Moreover, the as-prepared ECL immunosensor showed excellent performance and high stability. Finally, the proposed ECL sensor was applied to analyze OTA in coffee samples, confirming the desirable accuracy and practical applicability potential. Overall, this work presents a new nanomaterial for fabricating the sensing interface of immunosensors by harnessing natural waste as the source and a method for detecting toxic OTA in foods.
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Advanced Healthcare Materials
·
2021
·Vol. 11
·期 10
·2102682
·
IF 9.933
Dongxu Ma,Baiqi Chen,Yuanfang Li,Xueyuan Pang,Quanying Fu,Zihan Xiao,Zhonghong Shi,Xiaolei Li,Chongdai Luo,Zhang-kai Zhou,Yin Chen,Jianhua Zhou
The development of easy-to-use, low-cost, and visualized detection platforms for screening human dental caries and periodontal diseases is in urgent demand. In this work, a Au@Ag nanorods-poly(dimethylsiloxane) (Au@Ag NRs-PDMS) wearable mouthguard, which can visualize the tooth lesion sites through the color change of it at the corresponding locations, is presented. The Au@Ag NRs-PDMS composite exhibits a distinct color response to hydrogen sulfide (H 2 S) gas generated by bacterial decay at the lesion sites. Moreover, the Au@Ag NRs-PDMS mouthguard is demonstrated to own desired mechanical properties, excellent chemical stability, as well as good biocompatibility, and can accurately locate the lesion sites in human oral cavity. These findings suggest that the mouthguard has the potential to be utilized on a large scale to help people self-monitor their oral health in daily life, and treat oral diseases locally.
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VIBRATIONAL SPECTROSCOPY
·
2021
·
IF 2.507
Yuqian Liu,Lei Lei,Yeyu Wu,Yuyun Chen,Jun Yan,Weiwei Zhu,Xuecai Tan,Qi Wang
The quantitative determination of malachite green (MG) is of great importance in aquatic product safety. Although it has been testifying that sea urchin-like gold nanoparticles (SGNPs) have good enhancement effect, the practical application remains challenging for surface-enhanced Raman spectroscopy (SERS) due to poor stability. Here, sea urchin-like Au@SiO 2 nanoparticles (SG@SiO 2 NPs) is designed and synthesized through a controllable and surfactant-free hydrothermal method to improve its stability. The morphology of SG@SiO 2 NPs and the SiO 2 shell thickness were adjusted to obtain good SERS performance. The SERS signal intensity was linear for MG, crystal violet (CV) and methylene blue (MB) at 1619 cm −1 , 1623 cm −1 and 1627 cm −1 over the concentration range of 10 −5 -10 −9 M, 10 −5 -10 −9 M and 10 −5 -10 −8 M, respectively. The substrate was easily used for MG detection with limit of detection (LOD) as low as 1.5 × 10 −9 M. The recovery of MG added to several tilapia fillets samples at different concentrations ranged from 90 % to 110 %. Results indicated that SERS substrate can be used for the determination of trace amounts of MG in tilapia and demonstrated the potential of SG@SiO 2 NPs SERS substrate in food analysis fields.
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PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
·
2021
·Vol. 38
·期 12
·2100160
·
IF 3.31
Zilun Tang,Jianyu Wu,Xiaochun Liu,Qiuping Su,Xingshan Yin,Zhiyi Huang,Xiaofeng Lin,Wenjing Lin,Guobin Yi
The fabrication of flexible surface-enhanced Raman scattering (SERS) substrates for sensitive detection on uneven or irregular surfaces is challenging. In this study, a flexible dual plasmonic SERS (FDPS) substrate rationally constructed using Au nanoparticle (AuNP) arrays/aligned Ag nanowires (AgNWs) and elastic polyurethane (PU) is demonstrated. It exhibits high sensitivity (detection limit of 10 −8 m for melamine and 10 −10 m for malachite green) and excellent reproducibility. The well-designed structure of AuNP arrays/aligned AgNWs fabricated using block copolymer self-assembly and oil–water–air interfacial self-assembly successfully enhances the electromagnetic field through plasmonic coupling. In addition, the FDPS substrate retains a high SERS sensitivity after exposure to air at room temperature for 30 days because of the high stability of AuNP arrays and antioxidation characteristic of the PU covered on the aligned AgNWs. Even after undergoing stretching, bending, and twisting for 100 cycles, the FDPS substrate maintains a stable SERS activity owing to the introduction of the elastic PU. This study demonstrates a potential application of SERS detection under practical conditions for irregular surfaces and may be helpful in the development of flexible sensors.
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